Experiment set6IT006 for Phaeobacter inhibens DSM 17395

Compare to:

marine broth with Thallium(I) acetate 0.002 mg/ml

200 most detrimental genes:

  gene name fitness t score description  
PGA1_c08590 +1.8 12.1 heme NO binding domain-containing protein compare
PGA1_c06280 +1.8 4.2 cytochrome c oxidase assembly protein CtaG compare
PGA1_c08600 +1.7 13.8 diguanylate cyclase (GGDEF) domain-containing protein compare
PGA1_c20140 +1.6 9.1 putative arginine-tRNA-protein transferase compare
PGA1_65p00450 +1.6 3.6 UDP-glucose 6-dehydrogenase Ugd compare
PGA1_c34880 +1.6 12.9 putative response regulator compare
PGA1_c33190 +1.6 7.6 putative anti-sigma-B factor antagonist compare
PGA1_c34890 +1.4 11.2 putative histidine-containing phosphotransfer protein compare
PGA1_262p01600 +1.2 2.2 putative ABC transporter, ATP binding protein compare
PGA1_c02460 +1.1 9.7 hypothetical protein compare
PGA1_65p00390 +1.1 3.5 UDP-galactopyranose mutase Glf compare
PGA1_262p01410 +1.1 2.4 malate/L-lactate dehydrogenase-like protein compare
PGA1_262p01165 +1.1 2.3 hypothetical protein compare
PGA1_c34480 +1.1 3.7 UTP--glucose-1-phosphate uridylyltransferase CelA compare
PGA1_c02440 +1.0 8.4 putative ATP-binding/permease fusion ABC transporter compare
PGA1_c19200 +1.0 2.5 Predicted Fe-S protein compare
PGA1_c11540 +1.0 1.6 gamma-glutamylputrescine synthetase PuuA compare
PGA1_65p00180 +1.0 1.7 putative sugar transferase compare
PGA1_65p00280 +1.0 2.2 Protein of unknown function (DUF2793)./Domain of unknown function (DUF3476). compare
PGA1_c15380 +1.0 1.5 Uncharacterized conserved protein compare
PGA1_c02450 +1.0 7.4 putative outer membrane efflux protein compare
PGA1_c10200 +1.0 2.3 molybdenum cofactor biosynthesis protein A compare
PGA1_c14800 +1.0 1.8 nitrogen regulation protein NtrY compare
PGA1_c14190 +0.9 5.7 putative transcriptional regulator, AraC family compare
PGA1_c14970 +0.9 1.4 hypothetical protein compare
PGA1_c01830 +0.9 2.2 Uncharacterized conserved small protein compare
PGA1_78p00170 +0.9 1.5 putative sn-glycerol-3-phosphate transport system permease protein UgpA compare
PGA1_c02430 +0.9 5.5 type I secretion membrane fusion protein, HlyD family compare
PGA1_c17680 +0.9 2.1 hypothetical protein compare
PGA1_c12770 +0.8 1.7 hypothetical protein compare
PGA1_262p00660 +0.8 1.7 Predicted periplasmic protein compare
PGA1_c13510 +0.8 1.7 hypothetical protein compare
PGA1_c26780 +0.8 2.2 cold shock protein CspA compare
PGA1_c06590 +0.8 2.1 putative transcriptional regulator, AsnC family compare
PGA1_c31270 +0.8 7.3 putative glycosyltransferase / polysaccharide deacetylase compare
PGA1_c33490 +0.8 1.4 inositol-1-monophosphatase SuhB compare
PGA1_c31260 +0.8 7.0 Protein of unknown function (DUF3131). compare
PGA1_c18580 +0.8 2.4 hypothetical protein compare
PGA1_c29060 +0.8 2.0 HTH-type transcriptional regulator PecS compare
PGA1_78p00490 +0.8 1.0 putative HTH-type transcriptional regulator compare
PGA1_c35920 +0.7 1.1 thiamine kinase ThiK-like protein compare
PGA1_c12550 +0.7 2.2 hypothetical protein compare
PGA1_c23540 +0.7 4.2 O-succinylhomoserine sulfhydrylase MetZ compare
PGA1_c16190 +0.7 2.0 hypothetical protein compare
PGA1_c27240 +0.7 1.7 hypothetical protein compare
PGA1_262p00470 +0.7 1.3 Plasmid stabilization system protein compare
PGA1_c26560 +0.7 2.5 Predicted dioxygenase of extradiol dioxygenase family compare
PGA1_c14560 +0.7 1.3 homoserine O-succinyltransferase MetA compare
PGA1_c30000 +0.7 2.7 ATP-dependent Clp protease adaptor protein ClpS compare
PGA1_c18380 +0.7 1.1 Phage Head-Tail Attachment. compare
PGA1_c19090 +0.7 1.9 Protein required for attachment to host cells compare
PGA1_c11710 +0.7 3.1 transcriptional regulator, LysR family compare
PGA1_78p00060 +0.7 1.1 Uncharacterized protein conserved in bacteria compare
PGA1_c11470 +0.7 2.0 acetyltransferase domain-containing protein compare
PGA1_c08450 +0.6 0.9 Predicted membrane protein (DUF2061). compare
PGA1_65p00170 +0.6 2.2 putative capsular polysaccharide biosynthesis protein compare
PGA1_c08500 +0.6 2.2 hypothetical protein compare
PGA1_c15200 +0.6 1.5 ATP-dependent reduction of co(II)balamin (RamA-like) (EC:2.1.1.13) (from data) compare
PGA1_c15950 +0.6 4.7 putative branched-chain amino acid transport system, permease protein compare
PGA1_c31880 +0.6 5.6 signal transduction histidine kinase compare
PGA1_262p02110 +0.6 1.8 putative chemotaxis protein CheW compare
PGA1_262p01490 +0.6 1.6 putative sarcosine oxidase, gamma subunit compare
PGA1_c15420 +0.6 2.2 Yip1 domain. compare
PGA1_c24110 +0.6 2.5 hypothetical protein compare
PGA1_65p00030 +0.6 2.0 putative type I secretion system ATPase compare
PGA1_c35410 +0.6 2.6 hypothetical protein compare
PGA1_c19910 +0.6 1.9 Protein of unknown function (DUF1499). compare
PGA1_78p00140 +0.6 0.8 Sugar phosphate isomerases/epimerases compare
PGA1_c23210 +0.6 2.2 hypothetical protein compare
PGA1_c04010 +0.6 1.1 putative universal stress protein compare
PGA1_262p01270 +0.6 1.7 Uncharacterized conserved protein compare
PGA1_262p00930 +0.6 1.7 hypothetical protein compare
PGA1_c06480 +0.6 1.5 hypothetical protein compare
PGA1_c16180 +0.6 2.7 TRAP transporter solute receptor, TAXI family compare
PGA1_c05390 +0.6 2.3 glycosyl transferase compare
PGA1_c25130 +0.6 2.4 Methylase involved in ubiquinone/menaquinone biosynthesis compare
PGA1_78p00270 +0.6 1.2 lipoyl synthase LipA compare
PGA1_c15660 +0.6 2.5 enoyl-CoA hydratase/isomerase family protein compare
PGA1_65p00040 +0.6 2.2 RTX toxins and related Ca2+-binding proteins compare
PGA1_262p00760 +0.6 1.7 transcriptional regulator, AsnC family compare
PGA1_c19790 +0.6 1.8 putative DNA polymerase III chi subunit, holC compare
PGA1_262p01580 +0.6 1.1 putative metal ion uptake regulator compare
PGA1_c20530 +0.5 2.5 putative transcriptional regulator compare
PGA1_262p00880 +0.5 1.6 ABC transporter, integral inner membrane component compare
PGA1_c12750 +0.5 2.4 Predicted transporter component compare
PGA1_c13100 +0.5 2.6 aldo / keto reductase compare
PGA1_c13430 +0.5 1.7 C4-dicarboxylate transport sensor protein DctB compare
PGA1_c34940 +0.5 1.4 Putative sterol carrier protein compare
PGA1_65p00350 +0.5 3.0 hemolysin-like protein compare
PGA1_c02130 +0.5 1.9 conserved hypothetical protein YidD compare
PGA1_c10970 +0.5 2.4 ribosome small subunit-dependent GTPase A compare
PGA1_c13540 +0.5 3.1 Uncharacterized protein conserved in bacteria compare
PGA1_c14760 +0.5 0.9 bifunctional enzyme IspDF compare
PGA1_c12310 +0.5 3.7 glucans biosynthesis protein G compare
PGA1_c15940 +0.5 3.5 putative branched-chain amino acid transport system, permease protein compare
PGA1_c08920 +0.5 3.0 3,4-dihydroxy-2-butanone 4-phosphate synthase RibB compare
PGA1_c28320 +0.5 2.3 ABC transporter, ATP-binding protein compare
PGA1_c27450 +0.5 2.6 Demethylmenaquinone methyltransferase compare
PGA1_262p00750 +0.5 1.6 Threonine dehydratase compare
PGA1_c16420 +0.5 1.5 putative phospholipase / carboxylesterase compare
PGA1_c06980 +0.5 1.0 hypothetical protein compare
PGA1_c15060 +0.5 2.7 carbohydrate kinase, PfkB family compare
PGA1_c18560 +0.5 1.5 hypothetical protein compare
PGA1_c06370 +0.5 1.9 adenine phosphoribosyltransferase Apt compare
PGA1_262p01010 +0.5 1.4 dipeptide transport ATP-binding protein DppD compare
PGA1_c11480 +0.5 1.6 Uncharacterized conserved protein compare
PGA1_262p00950 +0.5 1.0 thioesterase superfamily protein TdaD compare
PGA1_c32130 +0.5 3.1 nicotinate phosphoribosyltransferase PncB compare
PGA1_c06000 +0.5 1.4 chorismate mutase-like protein compare
PGA1_c27900 +0.5 1.5 ligand-binding UTRA domain-containing protein compare
PGA1_c29040 +0.5 2.2 endonuclease III compare
PGA1_c24970 +0.5 2.6 putative hydrolase, HAD superfamily compare
PGA1_c29590 +0.5 2.2 hypothetical protein compare
PGA1_c08670 +0.5 2.1 transcriptional regulator, TetR family compare
PGA1_c10690 +0.5 1.4 hypothetical protein compare
PGA1_262p02350 +0.5 1.9 histidine transport ATP-binding protein HisP compare
PGA1_c01960 +0.5 1.6 putative hydrolase compare
PGA1_262p00060 +0.5 1.2 putative glycosyl transferase compare
PGA1_c33170 +0.5 2.3 putative sensor protein compare
PGA1_c29440 +0.4 2.6 hypothetical protein compare
PGA1_c17830 +0.4 1.2 putative gene transfer agent prohead protease compare
PGA1_c27660 +0.4 1.2 hypothetical protein compare
PGA1_c10270 +0.4 2.5 hypothetical protein compare
PGA1_c09990 +0.4 2.0 Uncharacterized protein conserved in bacteria compare
PGA1_c02990 +0.4 2.3 hypothetical protein compare
PGA1_c12930 +0.4 1.7 hypothetical protein compare
PGA1_c25070 +0.4 1.7 H-type lectin domain. compare
PGA1_c03940 +0.4 1.7 putative permease protein compare
PGA1_c34120 +0.4 1.1 HTH-type transcriptional regulator PetP compare
PGA1_c18510 +0.4 2.0 Protein of unknown function (DUF1064). compare
PGA1_c05180 +0.4 1.7 Predicted small integral membrane protein compare
PGA1_c33220 +0.4 1.4 hemimethylated DNA-binding protein, YccV-like compare
PGA1_c12320 +0.4 2.2 Uncharacterized protein conserved in bacteria compare
PGA1_c14140 +0.4 1.1 hypothetical protein compare
PGA1_c10680 +0.4 1.5 helix-turn-helix domain-containing protein compare
PGA1_262p00270 +0.4 1.4 transcriptional regulator, GntR family compare
PGA1_c04730 +0.4 1.6 hypothetical protein compare
PGA1_c04430 +0.4 3.0 putative peptide permease protein compare
PGA1_c08930 +0.4 2.1 6,7-dimethyl-8-ribityllumazine synthase RibH compare
PGA1_c36270 +0.4 1.2 hypothetical protein compare
PGA1_c01060 +0.4 1.1 ribonuclease 3 compare
PGA1_c25960 +0.4 1.5 putative biopolymer transport protein compare
PGA1_c11620 +0.4 1.8 Uncharacterized conserved protein compare
PGA1_c18570 +0.4 1.3 hypothetical protein compare
PGA1_c04090 +0.4 2.4 beta-ketoadipyl-CoA thiolase PaaJ compare
PGA1_c08300 +0.4 1.6 hypothetical protein compare
PGA1_262p01250 +0.4 0.8 transcriptional regulator, crp family compare
PGA1_c21670 +0.4 2.1 betaine aldehyde dehydrogenase BetB compare
PGA1_c13080 +0.4 1.4 transcriptional regulator, GntR family compare
PGA1_c07020 +0.4 2.2 Poly(3-hydroxybutyrate) depolymerase compare
PGA1_c05140 +0.4 2.2 D-amino acid dehydrogenase small subunit compare
PGA1_c08690 +0.4 1.6 hypothetical protein compare
PGA1_c08780 +0.4 0.8 hypothetical protein compare
PGA1_262p01750 +0.4 1.9 putative amidohydrolase compare
PGA1_262p00900 +0.4 0.7 ABC transporter, ATP-binding protein compare
PGA1_c26950 +0.4 1.5 putative exopolysaccharide synthesis protein ExoD compare
PGA1_c19030 +0.4 2.3 putative efflux transporter, RND family, MFP subunit compare
PGA1_262p01120 +0.4 0.7 hypothetical protein compare
PGA1_c28710 +0.4 2.1 allophanate hydrolase, subunit 2 compare
PGA1_262p01400 +0.4 1.7 dimethylglycine dehydrogenase DmgdH compare
PGA1_c09260 +0.4 1.2 Uncharacterized conserved protein compare
PGA1_c00950 +0.4 2.1 Protein of unknown function (DUF3429). compare
PGA1_c21580 +0.4 1.3 hypothetical protein compare
PGA1_c26850 +0.4 0.8 Predicted metal-binding protein compare
PGA1_c05230 +0.4 2.8 ABC transporter, extracellular solute-binding protein compare
PGA1_c08220 +0.4 1.6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily. compare
PGA1_262p00730 +0.4 0.5 putative signal transduction histidine kinase compare
PGA1_c24220 +0.4 0.9 ornithine carbamoyltransferase ArgF compare
PGA1_c03460 +0.4 2.3 hypothetical protein compare
PGA1_c04220 +0.4 1.3 putative phosphonate metabolism compare
PGA1_c20370 +0.4 1.4 tRNA-Asp compare
PGA1_c15890 +0.4 2.6 extracellular ligand-binding receptor compare
PGA1_c11460 +0.4 1.3 hypothetical protein compare
PGA1_c15100 +0.4 1.3 tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ compare
PGA1_c13990 +0.4 1.6 Novel Xylose regulator from LacI family (from data) compare
PGA1_c22620 +0.3 2.0 signal transduction protein, FIST domain compare
PGA1_c18530 +0.3 1.4 hypothetical protein compare
PGA1_c09160 +0.3 1.9 Uncharacterized protein conserved in bacteria compare
PGA1_c05250 +0.3 2.1 2-keto-3-deoxy-galactonokinase compare
PGA1_c32280 +0.3 1.5 Uncharacterized protein conserved in bacteria compare
PGA1_c20660 +0.3 1.4 TRAP transporter for fumarate, succinate, L-malate, and 2-oxogulatarate, large permease component (from data) compare
PGA1_c20910 +0.3 1.2 PHA synthesis repressor protein PhaR compare
PGA1_c08850 +0.3 1.4 secondary thiamine-phosphate synthase enzyme compare
PGA1_78p00030 +0.3 0.6 putative multicopper oxidase compare
PGA1_c15040 +0.3 1.3 Uncharacterized conserved protein compare
PGA1_c34230 +0.3 1.9 putative HTH-type transcriptional regulator, AraC family compare
PGA1_c13530 +0.3 1.5 hypothetical protein compare
PGA1_c19180 +0.3 0.8 cytochrome c-type biogenesis protein CycH compare
PGA1_c11820 +0.3 2.2 putative esterase compare
PGA1_c14730 +0.3 2.2 ammonia channel compare
PGA1_c05260 +0.3 2.5 exopolysaccharide production protein ExoY-like protein compare
PGA1_c12630 +0.3 1.7 putative high-affinity branched-chain amino acid transport ATP-binding protein compare
PGA1_262p02180 +0.3 1.3 molybdate-binding periplasmic protein ModA compare
PGA1_c10020 +0.3 1.5 Putative protein-S-isoprenylcysteine methyltransferase compare
PGA1_c20120 +0.3 1.6 Protein of unknown function (DUF2852). compare
PGA1_c05630 +0.3 1.7 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF compare
PGA1_262p00290 +0.3 1.4 putative transcriptional regulator compare
PGA1_c34770 +0.3 2.1 Uncharacterized protein conserved in bacteria compare
PGA1_c01940 +0.3 1.2 crcB-like protein compare
PGA1_c13060 +0.3 0.6 sensor histidine kinase compare


Specific Phenotypes

For 12 genes in this experiment

For stress Thallium(I) acetate in Phaeobacter inhibens DSM 17395

For stress Thallium(I) acetate across organisms