Experiment set6IT005 for Methanococcus maripaludis S2

200 most important genes:

gene	name	fitness	t score	description
MMP_RS01175		-5.3	-8.2	triphosphoribosyl-dephospho-CoA synthase
MMP_RS06355		-4.6	-6.2	molybdenum cofactor biosynthesis protein MoaE
MMP_RS03015		-4.5	-13.5	GTP 3' 8-cyclase MoaA
MMP_RS06685		-4.5	-18.2	formate dehydrogenase H subunit alpha selenocysteine-containing
MMP_RS06700		-4.4	-20.5	hypothetical protein
MMP_RS06680		-4.4	-18.6	Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain
MMP_RS06350		-4.2	-13.6	HesA/MoeB/ThiF family protein
MMP_RS01020		-4.2	-2.1	3 4-dihydroxy-2-butanone-4-phosphate synthase
MMP_RS03315		-4.1	-2.8	ferrous iron transport protein A
MMP_RS05515		-4.0	-10.2	cyclic pyranopterin monophosphate synthase MoaC
MMP_RS08300		-3.8	-3.1	metal-sulfur cluster assembly factor
MMP_RS08635		-3.8	-3.9	UbiA family prenyltransferase
MMP_RS06345		-3.8	-16.3	formate dehydrogenase accessory sulfurtransferase FdhD
MMP_RS07635		-3.7	-10.7	MogA/MoaB family molybdenum cofactor biosynthesis protein
MMP_RS02010		-3.7	-15.8	PHP domain-containing protein
MMP_RS01985		-3.5	-12.2	F420-dependent methylenetetrahydromethanopterin dehydrogenase
MMP_RS00300		-3.5	-1.7	6 7-dimethyl-8-ribityllumazine synthase
MMP_RS01500		-3.4	-4.6	CBS domain-containing protein
MMP_RS06715		-3.3	-21.0	cache domain-containing protein
MMP_RS06720		-3.3	-12.8	response regulator transcription factor
MMP_RS08720		-3.2	-3.1	4Fe-4S binding protein
MMP_RS08820		-3.1	-7.4	hypothetical protein
MMP_RS08745		-3.0	-11.7	CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase
MMP_RS06630		-3.0	-2.0	UPF0058 family protein
MMP_RS00040		-2.9	-5.8	TIGR03576 family pyridoxal phosphate-dependent enzyme
MMP_RS06400		-2.9	-3.6	4Fe-4S binding protein
MMP_RS04780		-2.8	-5.2	ribonuclease P
MMP_RS08460		-2.8	-3.7	proteasome-activating nucleotidase
MMP_RS04605		-2.8	-6.5	cobalt ECF transporter T component CbiQ
MMP_RS04900		-2.7	-21.0	hypothetical protein
MMP_RS07445		-2.7	-7.3	helix-turn-helix domain-containing protein
MMP_RS02195		-2.7	-6.1	tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
MMP_RS04775		-2.7	-6.1	adenosylhomocysteinase
MMP_RS01755		-2.6	-2.3	DUF2097 domain-containing protein
MMP_RS04585		-2.6	-12.3	AIR synthase related protein
MMP_RS06705		-2.6	-10.0	formate/nitrite transporter family protein
MMP_RS00115		-2.5	-15.4	radical SAM protein
MMP_RS01220		-2.5	-13.9	hypothetical protein
MMP_RS06295		-2.5	-11.6	methanogenesis marker 14 protein
MMP_RS02280		-2.5	-1.9	DUF211 domain-containing protein
MMP_RS06285		-2.5	-3.1	precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT
MMP_RS01005		-2.5	-2.6	riboflavin synthase
MMP_RS03600		-2.5	-4.3	triose-phosphate isomerase
MMP_RS03025		-2.5	-7.7	molybdenum cofactor guanylyltransferase
MMP_RS00895		-2.4	-7.2	hypothetical protein
MMP_RS07525		-2.4	-11.6	4Fe-4S binding protein
MMP_RS07845		-2.4	-4.5	LL-diaminopimelate aminotransferase
MMP_RS04615		-2.4	-5.7	PDGLE domain-containing protein
MMP_RS07630		-2.4	-2.4	ATP-binding cassette domain-containing protein
MMP_RS04620		-2.3	-13.3	cobalt transporter CbiM
MMP_RS00515		-2.3	-1.9	DUF655 domain-containing protein
MMP_RS02240		-2.2	-4.6	methanogenesis marker 7 protein
MMP_RS07600		-2.2	-3.2	Ni-sirohydrochlorin a c-diamide synthase
MMP_RS06120		-2.2	-3.2	UPF0147 family protein
MMP_RS03445		-2.2	-1.9	methanogenesis marker 17 protein
MMP_RS06975		-2.2	-3.3	sulfide-dependent adenosine diphosphate thiazole synthase
MMP_RS02800		-2.1	-8.3	nucleotidyltransferase domain-containing protein
MMP_RS01980		-2.1	-17.5	trimeric intracellular cation channel family protein
MMP_RS07005		-2.1	-1.2	4Fe-4S binding protein
MMP_RS02340		-2.1	-3.6	DNA-directed RNA polymerase subunit E''
MMP_RS04890		-2.1	-1.6	adenylyltransferase/cytidyltransferase family protein
MMP_RS07860		-2.1	-1.8	hypothetical protein
MMP_RS01610		-2.0	-5.2	hypothetical protein
MMP_RS06270		-2.0	-7.8	TIGR00300 family protein
MMP_RS08210		-2.0	-3.1	phosphatidylglycerophosphatase A
MMP_RS01795		-2.0	-3.4	methanogenesis marker 6 protein
MMP_RS06885		-2.0	-3.5	50S ribosome-binding GTPase
MMP_RS06105		-2.0	-9.4	hydrogenase maturation peptidase HycI
MMP_RS00110		-2.0	-3.6	hypothetical protein
MMP_RS00695		-1.9	-2.1	biotin--[acetyl-CoA-carboxylase] ligase
MMP_RS01225		-1.9	-8.9	DUF5379 domain-containing protein
MMP_RS06925		-1.9	-4.4	ribonuclease VapC4
MMP_RS03435		-1.9	-2.9	ketol-acid reductoisomerase
MMP_RS05920		-1.9	-1.1	50S ribosomal protein L37e
MMP_RS08645		-1.9	-9.8	UPF0179 family protein
MMP_RS03640		-1.8	-5.6	archaeal proteasome endopeptidase complex subunit beta
MMP_RS05765		-1.8	-6.8	M42 family metallopeptidase
MMP_RS06475		-1.8	-5.4	FAD-dependent oxidoreductase
MMP_RS01545		-1.8	-1.9	CBS domain-containing protein
MMP_RS07365		-1.8	-12.5	2-phosphoglycerate kinase
MMP_RS03035		-1.8	-4.4	4-hydroxy-tetrahydrodipicolinate synthase
MMP_RS01700		-1.8	-1.4	dihydroxy-acid dehydratase
MMP_RS03400		-1.8	-4.6	archease
MMP_RS02165		-1.8	-7.2	tRNA-dihydrouridine synthase
MMP_RS06895		-1.8	-2.7	selenocysteine-specific translation elongation factor
MMP_RS01265		-1.7	-2.5	hypothetical protein
MMP_RS05245		-1.7	-11.2	archaeosine biosynthesis radical SAM protein RaSEA
MMP_RS07605		-1.7	-5.3	diadenylate cyclase
MMP_RS02235		-1.7	-10.1	CBS domain-containing protein
MMP_RS03960		-1.7	-1.8	hypothetical protein
MMP_RS00685		-1.7	-4.1	2-phospho-L-lactate guanylyltransferase
MMP_RS01325		-1.7	-2.9	dihydroneopterin aldolase family protein
MMP_RS09020		-1.6	-2.4	hypothetical protein
MMP_RS06625		-1.6	-2.9	DNA primase
MMP_RS00305		-1.6	-2.9	phosphoribosyl-ATP diphosphatase
MMP_RS08435		-1.6	-4.0	Era-like GTP-binding protein
MMP_RS02355		-1.6	-4.0	30S ribosomal protein S27ae
MMP_RS04710		-1.6	-2.5	hypothetical protein
MMP_RS00620		-1.6	-6.9	4Fe-4S binding protein
MMP_RS00295		-1.6	-4.1	gamma carbonic anhydrase family protein
MMP_RS06175		-1.5	-5.2	winged helix-turn-helix transcriptional regulator
MMP_RS06230		-1.5	-3.4	helix-turn-helix domain-containing protein
MMP_RS02345		-1.5	-4.5	GTP-dependent dephospho-CoA kinase family protein
MMP_RS01380		-1.5	-5.7	PHP domain-containing protein
MMP_RS07735		-1.5	-1.6	2-ketoisovalerate ferredoxin oxidoreductase subunit alpha
MMP_RS06940		-1.5	-2.8	polyprenyl diphosphate synthase
MMP_RS08715		-1.5	-3.1	formylmethanofuran dehydrogenase subunit B
MMP_RS07435		-1.5	-2.8	GMP synthase subunit A
MMP_RS04870		-1.5	-5.9	TIGR02253 family HAD-type hydrolase
MMP_RS05540		-1.5	-3.8	hypothetical protein
MMP_RS07380		-1.5	-2.6	transcription elongation factor Spt5
MMP_RS01725		-1.5	-4.1	class I SAM-dependent methyltransferase family protein
MMP_RS01385		-1.4	-1.0	imidazole glycerol phosphate synthase subunit HisH
MMP_RS01250		-1.4	-5.7	tRNA (guanine(26)-N(2))-dimethyltransferase
MMP_RS07575		-1.4	-6.9	RNA ligase partner protein
MMP_RS08790		-1.4	-3.4	translation initiation factor IF-2 subunit alpha
MMP_RS01365		-1.4	-4.2	archaeal proteasome endopeptidase complex subunit alpha
MMP_RS07545		-1.4	-1.5	HTH domain-containing protein
MMP_RS03580		-1.4	-3.6	signal recognition particle-docking protein FtsY
MMP_RS07765		-1.4	-6.1	sodium:alanine symporter family protein
MMP_RS05430		-1.3	-4.5	TIGR00288 family NYN domain-containing protein
MMP_RS06200		-1.3	-7.7	M24 family metallopeptidase
MMP_RS06020		-1.3	-6.2	archaeoflavoprotein AfpA
MMP_RS07755		-1.3	-1.1	DUF555 domain-containing protein
MMP_RS06930		-1.3	-8.0	MBL fold metallo-hydrolase
MMP_RS07685		-1.2	-5.9	TIGR01212 family radical SAM protein
MMP_RS02190		-1.2	-3.4	sulfopyruvate decarboxylase subunit alpha
MMP_RS05510		-1.2	-5.8	Rrf2 family transcriptional regulator
MMP_RS01800		-1.2	-3.8	TIGR00303 family protein
MMP_RS04685		-1.2	-2.9	DUF126 domain-containing protein
MMP_RS01830		-1.2	-2.4	tRNA-Val
MMP_RS06315		-1.2	-1.3	cobalt-precorrin-7 (C(5))-methyltransferase
MMP_RS06370		-1.2	-4.1	biotin synthase BioB
MMP_RS06865		-1.2	-1.4	HypC/HybG/HupF family hydrogenase formation chaperone
MMP_RS07390		-1.1	-3.6	cell division protein FtsZ
MMP_RS08165		-1.1	-2.3	phosphoglycerate dehydrogenase
MMP_RS07730		-1.1	-2.3	pyruvate synthase subunit beta
MMP_RS03485		-1.1	-5.1	TIGR00267 family protein
MMP_RS03475		-1.1	-0.8	hypothetical protein
MMP_RS08320		-1.1	-6.0	molybdopterin molybdotransferase MoeA
MMP_RS05815		-1.1	-1.4	NOL1/NOP2/sun family putative RNA methylase
MMP_RS06215		-1.1	-3.3	30S ribosomal protein S6e
MMP_RS06730		-1.1	-1.9	phosphopantothenate/pantothenate synthetase
MMP_RS06340		-1.1	-5.3	phosphoadenosine phosphosulfate reductase family protein
MMP_RS01180		-1.0	-2.3	XTP/dITP diphosphatase
MMP_RS03095		-1.0	-6.7	diphthine synthase
MMP_RS00050		-1.0	-6.3	AarF/UbiB family protein
MMP_RS02145		-1.0	-4.7	winged helix-turn-helix transcriptional regulator
MMP_RS08445		-1.0	-3.9	DUF2099 family protein
MMP_RS02245		-1.0	-2.9	hypothetical protein
MMP_RS04695		-1.0	-4.5	selenide water dikinase SelD
MMP_RS05345		-1.0	-5.5	hypothetical protein
MMP_RS08615		-1.0	-2.8	flagellar protein G
MMP_RS07710		-1.0	-5.3	cell division protein FtsZ
MMP_RS00060		-1.0	-1.7	3-dehydroquinate synthase II
MMP_RS05875		-1.0	-6.2	hydroxyethylthiazole kinase
MMP_RS08200		-1.0	-8.1	archaeosine synthase subunit alpha
MMP_RS03250		-1.0	-2.7	MJ1244 family protein
MMP_RS03155		-1.0	-4.8	precorrin-6A reductase
MMP_RS08095		-1.0	-3.4	dethiobiotin synthase
MMP_RS05315		-1.0	-1.6	hypothetical protein
MMP_RS00985		-1.0	-3.9	CDC48 family AAA ATPase
MMP_RS07580		-0.9	-1.8	DUF356 domain-containing protein
MMP_RS05425		-0.9	-3.9	monovalent cation/H+ antiporter complex subunit F
MMP_RS04500		-0.9	-7.3	adenosylmethionine--8-amino-7-oxononanoate transaminase
MMP_RS03700		-0.9	-5.3	sodium:proton antiporter
MMP_RS02135		-0.9	-3.1	DUF5612 domain-containing protein
MMP_RS01840		-0.9	-5.6	TIGR00289 family protein
MMP_RS05845		-0.9	-1.8	tRNA-intron lyase
MMP_RS05545		-0.9	-3.9	pyridoxal phosphate-dependent aminotransferase
MMP_RS01075		-0.9	-2.4	hypothetical protein
MMP_RS07775		-0.9	-5.3	alanine dehydrogenase
MMP_RS08690		-0.9	-5.3	RNA-guided pseudouridylation complex pseudouridine synthase subunit Cbf5
MMP_RS03590		-0.9	-3.8	METTL5 family protein
MMP_RS08595		-0.9	-1.2	flagellar protein C
MMP_RS08100		-0.9	-4.6	8-amino-7-oxononanoate synthase
MMP_RS00555		-0.8	-3.9	MFS transporter
MMP_RS05250		-0.8	-1.4	NFYB/HAP3 family transcription factor subunit
MMP_RS05440		-0.8	-5.3	winged helix-turn-helix transcriptional regulator
MMP_RS02930		-0.8	-1.8	class I SAM-dependent methyltransferase
MMP_RS01745		-0.8	-3.2	AMP phosphorylase
MMP_RS00915		-0.8	-3.8	DUF116 domain-containing protein
MMP_RS04875		-0.8	-4.2	energy-converting hydrogenase B subunit P
MMP_RS06980		-0.8	-3.9	tRNA 2-thiocytidine biosynthesis TtcA family protein
MMP_RS07090		-0.8	-4.7	tRNA (adenine-N1)-methyltransferase
MMP_RS07200		-0.8	-3.3	[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
MMP_RS03205		-0.8	-1.4	peptidyl-tRNA hydrolase Pth2
MMP_RS05500		-0.8	-5.9	2-isopropylmalate synthase
MMP_RS09055		-0.8	-1.1	CAP domain-containing protein
MMP_RS08240		-0.8	-3.3	methanogenesis marker 16 metalloprotein
MMP_RS07385		-0.8	-1.1	protein translocase SEC61 complex subunit gamma
MMP_RS03305		-0.8	-3.3	winged helix-turn-helix domain-containing protein
MMP_RS00290		-0.8	-3.9	hypothetical protein
MMP_RS08105		-0.8	-4.3	6-carboxyhexanoate--CoA ligase
MMP_RS01045		-0.7	-3.9	diphthamide biosynthesis enzyme Dph2
MMP_RS03120		-0.7	-3.2	hypothetical protein
MMP_RS08330		-0.7	-3.3	NADH-quinone oxidoreductase subunit H
MMP_RS02955		-0.7	-2.1	DJ-1/PfpI family protein
MMP_RS05925		-0.7	-3.3	small nuclear ribonucleoprotein
MMP_RS02885		-0.7	-5.9	molybdopterin biosynthesis protein

Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in nutrient t1 experiments