Experiment set6IT004 for Methanococcus maripaludis S2

Compare to:

formate McAA folic acid dropout

200 most important genes:

  gene name fitness t score description  
MMP_RS06355 -6.3 -3.4 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS01175 -6.0 -7.9 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS06700 -5.0 -18.2 hypothetical protein compare
MMP_RS06350 -4.7 -10.2 HesA/MoeB/ThiF family protein compare
MMP_RS06685 -4.3 -18.3 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS06680 -4.3 -20.7 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS03015 -4.2 -16.4 GTP 3' 8-cyclase MoaA compare
MMP_RS01005 -4.2 -2.4 riboflavin synthase compare
MMP_RS08820 -4.0 -8.4 hypothetical protein compare
MMP_RS05515 -4.0 -11.2 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS06345 -3.7 -20.2 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS02010 -3.7 -16.3 PHP domain-containing protein compare
MMP_RS01755 -3.6 -3.0 DUF2097 domain-containing protein compare
MMP_RS01985 -3.6 -11.1 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS07005 -3.5 -1.4 4Fe-4S binding protein compare
MMP_RS08300 -3.4 -3.1 metal-sulfur cluster assembly factor compare
MMP_RS06720 -3.4 -16.0 response regulator transcription factor compare
MMP_RS08460 -3.4 -3.9 proteasome-activating nucleotidase compare
MMP_RS04605 -3.4 -7.7 cobalt ECF transporter T component CbiQ compare
MMP_RS06715 -3.2 -18.9 cache domain-containing protein compare
MMP_RS07635 -3.2 -10.5 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS07380 -3.1 -4.0 transcription elongation factor Spt5 compare
MMP_RS03600 -3.1 -4.7 triose-phosphate isomerase compare
MMP_RS06975 -3.0 -4.6 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS04900 -3.0 -23.7 hypothetical protein compare
MMP_RS07845 -3.0 -5.3 LL-diaminopimelate aminotransferase compare
MMP_RS03315 -3.0 -2.0 ferrous iron transport protein A compare
MMP_RS04890 -2.9 -2.0 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS01020 -2.8 -2.3 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS00300 -2.8 -1.8 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS08210 -2.8 -4.7 phosphatidylglycerophosphatase A compare
MMP_RS06295 -2.7 -10.7 methanogenesis marker 14 protein compare
MMP_RS04585 -2.7 -13.7 AIR synthase related protein compare
MMP_RS00040 -2.7 -5.6 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS00895 -2.6 -6.5 hypothetical protein compare
MMP_RS08745 -2.6 -11.7 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS07755 -2.6 -2.7 DUF555 domain-containing protein compare
MMP_RS06705 -2.5 -8.7 formate/nitrite transporter family protein compare
MMP_RS08720 -2.5 -3.0 4Fe-4S binding protein compare
MMP_RS07525 -2.5 -12.4 4Fe-4S binding protein compare
MMP_RS07605 -2.4 -5.4 diadenylate cyclase compare
MMP_RS03445 -2.4 -2.1 methanogenesis marker 17 protein compare
MMP_RS01220 -2.4 -11.3 hypothetical protein compare
MMP_RS01500 -2.4 -4.6 CBS domain-containing protein compare
MMP_RS00115 -2.3 -14.4 radical SAM protein compare
MMP_RS07445 -2.3 -6.2 helix-turn-helix domain-containing protein compare
MMP_RS02800 -2.2 -8.8 nucleotidyltransferase domain-containing protein compare
MMP_RS06285 -2.2 -4.3 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS01800 -2.2 -4.6 TIGR00303 family protein compare
MMP_RS01325 -2.2 -4.5 dihydroneopterin aldolase family protein compare
MMP_RS08790 -2.1 -4.5 translation initiation factor IF-2 subunit alpha compare
MMP_RS00515 -2.1 -2.0 DUF655 domain-containing protein compare
MMP_RS08715 -2.1 -2.5 formylmethanofuran dehydrogenase subunit B compare
MMP_RS02340 -2.1 -4.1 DNA-directed RNA polymerase subunit E'' compare
MMP_RS04615 -2.1 -4.7 PDGLE domain-containing protein compare
MMP_RS04775 -2.1 -4.8 adenosylhomocysteinase compare
MMP_RS01225 -2.1 -7.7 DUF5379 domain-containing protein compare
MMP_RS03025 -2.1 -6.6 molybdenum cofactor guanylyltransferase compare
MMP_RS02355 -2.1 -5.1 30S ribosomal protein S27ae compare
MMP_RS06400 -2.0 -2.4 4Fe-4S binding protein compare
MMP_RS06105 -2.0 -8.2 hydrogenase maturation peptidase HycI compare
MMP_RS04620 -2.0 -11.9 cobalt transporter CbiM compare
MMP_RS08435 -2.0 -3.1 Era-like GTP-binding protein compare
MMP_RS01265 -2.0 -3.1 hypothetical protein compare
MMP_RS03435 -2.0 -2.4 ketol-acid reductoisomerase compare
MMP_RS06475 -1.9 -6.4 FAD-dependent oxidoreductase compare
MMP_RS01795 -1.9 -2.4 methanogenesis marker 6 protein compare
MMP_RS09020 -1.9 -3.3 hypothetical protein compare
MMP_RS02195 -1.9 -4.6 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS01980 -1.9 -13.4 trimeric intracellular cation channel family protein compare
MMP_RS00695 -1.9 -2.3 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS00110 -1.9 -3.7 hypothetical protein compare
MMP_RS02280 -1.9 -1.8 DUF211 domain-containing protein compare
MMP_RS07365 -1.9 -11.2 2-phosphoglycerate kinase compare
MMP_RS03960 -1.8 -2.0 hypothetical protein compare
MMP_RS08635 -1.8 -2.5 UbiA family prenyltransferase compare
MMP_RS02240 -1.8 -4.3 methanogenesis marker 7 protein compare
MMP_RS00685 -1.8 -5.6 2-phospho-L-lactate guanylyltransferase compare
MMP_RS00620 -1.8 -7.9 4Fe-4S binding protein compare
MMP_RS08645 -1.8 -10.5 UPF0179 family protein compare
MMP_RS05245 -1.8 -10.4 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS02235 -1.8 -8.3 CBS domain-containing protein compare
MMP_RS03640 -1.7 -4.8 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS05550 -1.7 -1.3 cation:proton antiporter compare
MMP_RS01385 -1.7 -1.2 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS06925 -1.7 -3.7 ribonuclease VapC4 compare
MMP_RS07630 -1.7 -2.6 ATP-binding cassette domain-containing protein compare
MMP_RS07730 -1.7 -3.2 pyruvate synthase subunit beta compare
MMP_RS05920 -1.7 -1.1 50S ribosomal protein L37e compare
MMP_RS06270 -1.7 -6.0 TIGR00300 family protein compare
MMP_RS06120 -1.7 -2.8 UPF0147 family protein compare
MMP_RS06895 -1.6 -2.6 selenocysteine-specific translation elongation factor compare
MMP_RS03035 -1.6 -3.9 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS05765 -1.6 -5.7 M42 family metallopeptidase compare
MMP_RS07600 -1.6 -4.6 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS03580 -1.6 -4.5 signal recognition particle-docking protein FtsY compare
MMP_RS06885 -1.6 -3.5 50S ribosome-binding GTPase compare
MMP_RS01545 -1.6 -1.9 CBS domain-containing protein compare
MMP_RS07545 -1.6 -2.1 HTH domain-containing protein compare
MMP_RS06020 -1.6 -6.7 archaeoflavoprotein AfpA compare
MMP_RS01365 -1.5 -3.4 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS06625 -1.5 -2.9 DNA primase compare
MMP_RS04870 -1.5 -5.0 TIGR02253 family HAD-type hydrolase compare
MMP_RS03205 -1.5 -2.5 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS07575 -1.5 -4.0 RNA ligase partner protein compare
MMP_RS06175 -1.5 -5.2 winged helix-turn-helix transcriptional regulator compare
MMP_RS04780 -1.5 -3.6 ribonuclease P compare
MMP_RS02345 -1.5 -4.4 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS06200 -1.4 -8.9 M24 family metallopeptidase compare
MMP_RS07435 -1.4 -3.1 GMP synthase subunit A compare
MMP_RS04710 -1.4 -2.9 hypothetical protein compare
MMP_RS01380 -1.4 -5.5 PHP domain-containing protein compare
MMP_RS00060 -1.3 -2.8 3-dehydroquinate synthase II compare
MMP_RS01610 -1.3 -3.8 hypothetical protein compare
MMP_RS02165 -1.3 -5.9 tRNA-dihydrouridine synthase compare
MMP_RS08165 -1.3 -2.5 phosphoglycerate dehydrogenase compare
MMP_RS06215 -1.3 -4.4 30S ribosomal protein S6e compare
MMP_RS07765 -1.3 -7.9 sodium:alanine symporter family protein compare
MMP_RS06230 -1.3 -3.0 helix-turn-helix domain-containing protein compare
MMP_RS06340 -1.3 -7.0 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS06865 -1.2 -1.6 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS05540 -1.2 -2.7 hypothetical protein compare
MMP_RS03485 -1.2 -3.3 TIGR00267 family protein compare
MMP_RS00305 -1.2 -1.9 phosphoribosyl-ATP diphosphatase compare
MMP_RS01250 -1.2 -4.0 tRNA (guanine(26)-N(2))-dimethyltransferase compare
MMP_RS08320 -1.2 -5.9 molybdopterin molybdotransferase MoeA compare
MMP_RS00295 -1.2 -3.3 gamma carbonic anhydrase family protein compare
MMP_RS07685 -1.1 -5.5 TIGR01212 family radical SAM protein compare
MMP_RS06930 -1.1 -6.9 MBL fold metallo-hydrolase compare
MMP_RS03475 -1.1 -0.9 hypothetical protein compare
MMP_RS08200 -1.1 -8.9 archaeosine synthase subunit alpha compare
MMP_RS04685 -1.1 -2.5 DUF126 domain-containing protein compare
MMP_RS02190 -1.1 -4.3 sulfopyruvate decarboxylase subunit alpha compare
MMP_RS03095 -1.1 -5.7 diphthine synthase compare
MMP_RS07750 -1.1 -4.5 DUF357 domain-containing protein compare
MMP_RS08095 -1.1 -6.2 dethiobiotin synthase compare
MMP_RS03400 -1.1 -2.9 archease compare
MMP_RS00050 -1.1 -5.6 AarF/UbiB family protein compare
MMP_RS05430 -1.1 -4.3 TIGR00288 family NYN domain-containing protein compare
MMP_RS05510 -1.1 -4.0 Rrf2 family transcriptional regulator compare
MMP_RS05815 -1.1 -1.6 NOL1/NOP2/sun family putative RNA methylase compare
MMP_RS06370 -1.1 -3.3 biotin synthase BioB compare
MMP_RS05545 -1.1 -4.3 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS08940 -1.0 -1.8 MetS family NSS transporter small subunit compare
MMP_RS05875 -1.0 -5.0 hydroxyethylthiazole kinase compare
MMP_RS02135 -1.0 -3.3 DUF5612 domain-containing protein compare
MMP_RS04720 -1.0 -2.6 DedA family protein compare
MMP_RS08100 -1.0 -6.7 8-amino-7-oxononanoate synthase compare
MMP_RS06730 -1.0 -2.0 phosphopantothenate/pantothenate synthetase compare
MMP_RS01745 -1.0 -3.6 AMP phosphorylase compare
MMP_RS01725 -1.0 -2.9 class I SAM-dependent methyltransferase family protein compare
MMP_RS01180 -1.0 -1.2 XTP/dITP diphosphatase compare
MMP_RS07200 -1.0 -5.1 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS04500 -1.0 -7.3 adenosylmethionine--8-amino-7-oxononanoate transaminase compare
MMP_RS06940 -1.0 -2.5 polyprenyl diphosphate synthase compare
MMP_RS03080 -0.9 -1.8 universal stress protein compare
MMP_RS07425 -0.9 -4.2 GTP-binding protein compare
MMP_RS01830 -0.9 -2.2 tRNA-Val compare
MMP_RS04695 -0.9 -4.3 selenide water dikinase SelD compare
MMP_RS02145 -0.9 -4.9 winged helix-turn-helix transcriptional regulator compare
MMP_RS03590 -0.9 -3.9 METTL5 family protein compare
MMP_RS02930 -0.9 -1.6 class I SAM-dependent methyltransferase compare
MMP_RS02245 -0.9 -2.4 hypothetical protein compare
MMP_RS06315 -0.9 -1.1 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS05555 -0.9 -1.7 DUF4040 domain-containing protein compare
MMP_RS03250 -0.9 -3.2 MJ1244 family protein compare
MMP_RS05345 -0.9 -4.2 hypothetical protein compare
MMP_RS03155 -0.8 -5.3 precorrin-6A reductase compare
MMP_RS05500 -0.8 -5.1 2-isopropylmalate synthase compare
MMP_RS08690 -0.8 -3.8 RNA-guided pseudouridylation complex pseudouridine synthase subunit Cbf5 compare
MMP_RS01840 -0.8 -4.3 TIGR00289 family protein compare
MMP_RS07580 -0.8 -2.0 DUF356 domain-containing protein compare
MMP_RS07710 -0.8 -3.5 cell division protein FtsZ compare
MMP_RS03700 -0.8 -4.7 sodium:proton antiporter compare
MMP_RS04955 -0.8 -3.2 DNA topoisomerase I compare
MMP_RS00555 -0.8 -3.2 MFS transporter compare
MMP_RS03305 -0.7 -4.4 winged helix-turn-helix domain-containing protein compare
MMP_RS05845 -0.7 -1.7 tRNA-intron lyase compare
MMP_RS05800 -0.7 -4.5 B12-binding domain-containing radical SAM protein compare
MMP_RS02605 -0.7 -1.0 MotA/TolQ/ExbB proton channel family protein compare
MMP_RS00290 -0.7 -3.3 hypothetical protein compare
MMP_RS02885 -0.7 -6.1 molybdopterin biosynthesis protein compare
MMP_RS01575 -0.7 -3.8 aldolase compare
MMP_RS08105 -0.7 -3.4 6-carboxyhexanoate--CoA ligase compare
MMP_RS00130 -0.7 -1.2 nickel-responsive transcriptional regulator NikR compare
MMP_RS05440 -0.7 -5.0 winged helix-turn-helix transcriptional regulator compare
MMP_RS03120 -0.7 -2.4 hypothetical protein compare
MMP_RS03470 -0.7 -4.8 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS05250 -0.7 -1.4 NFYB/HAP3 family transcription factor subunit compare
MMP_RS06980 -0.7 -4.2 tRNA 2-thiocytidine biosynthesis TtcA family protein compare
MMP_RS00985 -0.7 -3.1 CDC48 family AAA ATPase compare
MMP_RS07390 -0.7 -1.6 cell division protein FtsZ compare
MMP_RS03210 -0.7 -5.0 tRNA guanosine(15) transglycosylase TgtA compare
MMP_RS01700 -0.7 -0.9 dihydroxy-acid dehydratase compare
MMP_RS05795 -0.7 -2.4 redox-regulated ATPase YchF compare
MMP_RS05925 -0.7 -2.8 small nuclear ribonucleoprotein compare
MMP_RS07090 -0.7 -3.6 tRNA (adenine-N1)-methyltransferase compare
MMP_RS04090 -0.6 -1.4 hypothetical protein compare
MMP_RS08595 -0.6 -1.0 flagellar protein C compare
MMP_RS05425 -0.6 -2.2 monovalent cation/H+ antiporter complex subunit F compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in nutrient t1 experiments