Experiment set6IT003 for Methanococcus maripaludis S2

200 most important genes:

gene	name	fitness	t score	description
MMP_RS08300		-5.2	-2.3	metal-sulfur cluster assembly factor
MMP_RS00300		-5.1	-1.4	6 7-dimethyl-8-ribityllumazine synthase
MMP_RS01175		-5.1	-6.2	triphosphoribosyl-dephospho-CoA synthase
MMP_RS06355		-5.1	-4.3	molybdenum cofactor biosynthesis protein MoaE
MMP_RS06680		-4.9	-19.5	Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain
MMP_RS06700		-4.7	-14.9	hypothetical protein
MMP_RS02280		-4.5	-1.7	DUF211 domain-containing protein
MMP_RS06685		-4.4	-20.4	formate dehydrogenase H subunit alpha selenocysteine-containing
MMP_RS06350		-4.4	-9.6	HesA/MoeB/ThiF family protein
MMP_RS06345		-4.1	-21.1	formate dehydrogenase accessory sulfurtransferase FdhD
MMP_RS01005		-4.0	-2.1	riboflavin synthase
MMP_RS05515		-4.0	-12.3	cyclic pyranopterin monophosphate synthase MoaC
MMP_RS06400		-4.0	-2.9	4Fe-4S binding protein
MMP_RS03015		-3.8	-17.2	GTP 3' 8-cyclase MoaA
MMP_RS07635		-3.7	-13.8	MogA/MoaB family molybdenum cofactor biosynthesis protein
MMP_RS01020		-3.7	-1.9	3 4-dihydroxy-2-butanone-4-phosphate synthase
MMP_RS02010		-3.5	-12.5	PHP domain-containing protein
MMP_RS08635		-3.5	-3.3	UbiA family prenyltransferase
MMP_RS07005		-3.4	-1.2	4Fe-4S binding protein
MMP_RS03315		-3.2	-2.4	ferrous iron transport protein A
MMP_RS08745		-3.2	-10.6	CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase
MMP_RS06715		-3.2	-19.1	cache domain-containing protein
MMP_RS07630		-3.1	-2.7	ATP-binding cassette domain-containing protein
MMP_RS01985		-3.0	-9.2	F420-dependent methylenetetrahydromethanopterin dehydrogenase
MMP_RS06720		-3.0	-13.5	response regulator transcription factor
MMP_RS00305		-2.9	-3.7	phosphoribosyl-ATP diphosphatase
MMP_RS01500		-2.9	-3.2	CBS domain-containing protein
MMP_RS06705		-2.8	-12.9	formate/nitrite transporter family protein
MMP_RS06975		-2.8	-5.1	sulfide-dependent adenosine diphosphate thiazole synthase
MMP_RS04605		-2.7	-9.8	cobalt ECF transporter T component CbiQ
MMP_RS04900		-2.6	-20.1	hypothetical protein
MMP_RS00040		-2.6	-5.3	TIGR03576 family pyridoxal phosphate-dependent enzyme
MMP_RS01980		-2.6	-17.1	trimeric intracellular cation channel family protein
MMP_RS03960		-2.6	-1.9	hypothetical protein
MMP_RS04585		-2.6	-12.3	AIR synthase related protein
MMP_RS08820		-2.6	-9.2	hypothetical protein
MMP_RS07845		-2.6	-3.9	LL-diaminopimelate aminotransferase
MMP_RS07445		-2.5	-5.8	helix-turn-helix domain-containing protein
MMP_RS01220		-2.5	-7.4	hypothetical protein
MMP_RS03025		-2.5	-8.5	molybdenum cofactor guanylyltransferase
MMP_RS06285		-2.5	-4.4	precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT
MMP_RS07730		-2.5	-3.7	pyruvate synthase subunit beta
MMP_RS06625		-2.5	-3.1	DNA primase
MMP_RS06630		-2.4	-1.9	UPF0058 family protein
MMP_RS04780		-2.4	-3.6	ribonuclease P
MMP_RS07525		-2.4	-9.4	4Fe-4S binding protein
MMP_RS08720		-2.3	-2.7	4Fe-4S binding protein
MMP_RS06295		-2.3	-8.1	methanogenesis marker 14 protein
MMP_RS03600		-2.3	-3.8	triose-phosphate isomerase
MMP_RS04775		-2.3	-4.8	adenosylhomocysteinase
MMP_RS06370		-2.3	-7.7	biotin synthase BioB
MMP_RS01225		-2.3	-10.2	DUF5379 domain-containing protein
MMP_RS01755		-2.2	-2.2	DUF2097 domain-containing protein
MMP_RS08460		-2.2	-3.3	proteasome-activating nucleotidase
MMP_RS08210		-2.1	-3.4	phosphatidylglycerophosphatase A
MMP_RS04615		-2.1	-6.0	PDGLE domain-containing protein
MMP_RS08645		-2.1	-9.4	UPF0179 family protein
MMP_RS07765		-2.1	-8.0	sodium:alanine symporter family protein
MMP_RS00110		-2.0	-3.2	hypothetical protein
MMP_RS06105		-2.0	-9.1	hydrogenase maturation peptidase HycI
MMP_RS01265		-2.0	-2.5	hypothetical protein
MMP_RS08105		-2.0	-9.4	6-carboxyhexanoate--CoA ligase
MMP_RS08100		-2.0	-8.0	8-amino-7-oxononanoate synthase
MMP_RS00115		-2.0	-13.5	radical SAM protein
MMP_RS04500		-2.0	-12.7	adenosylmethionine--8-amino-7-oxononanoate transaminase
MMP_RS05550		-2.0	-1.2	cation:proton antiporter
MMP_RS06270		-1.9	-7.0	TIGR00300 family protein
MMP_RS08095		-1.9	-8.8	dethiobiotin synthase
MMP_RS07380		-1.9	-3.7	transcription elongation factor Spt5
MMP_RS07645		-1.9	-9.3	aldehyde dehydrogenase family protein
MMP_RS07735		-1.9	-1.7	2-ketoisovalerate ferredoxin oxidoreductase subunit alpha
MMP_RS07600		-1.9	-3.8	Ni-sirohydrochlorin a c-diamide synthase
MMP_RS03640		-1.9	-6.0	archaeal proteasome endopeptidase complex subunit beta
MMP_RS02340		-1.9	-3.7	DNA-directed RNA polymerase subunit E''
MMP_RS07605		-1.9	-3.8	diadenylate cyclase
MMP_RS04620		-1.9	-11.1	cobalt transporter CbiM
MMP_RS08790		-1.8	-2.8	translation initiation factor IF-2 subunit alpha
MMP_RS03435		-1.8	-2.2	ketol-acid reductoisomerase
MMP_RS02195		-1.8	-4.1	tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
MMP_RS02240		-1.8	-4.2	methanogenesis marker 7 protein
MMP_RS03580		-1.8	-5.5	signal recognition particle-docking protein FtsY
MMP_RS00620		-1.7	-6.8	4Fe-4S binding protein
MMP_RS09020		-1.7	-2.2	hypothetical protein
MMP_RS00895		-1.7	-6.4	hypothetical protein
MMP_RS02800		-1.7	-5.3	nucleotidyltransferase domain-containing protein
MMP_RS02355		-1.7	-4.0	30S ribosomal protein S27ae
MMP_RS01795		-1.7	-2.2	methanogenesis marker 6 protein
MMP_RS00295		-1.7	-3.5	gamma carbonic anhydrase family protein
MMP_RS07555		-1.7	-1.1	monovalent cation/H+ antiporter subunit E
MMP_RS00685		-1.6	-4.7	2-phospho-L-lactate guanylyltransferase
MMP_RS06215		-1.6	-3.8	30S ribosomal protein S6e
MMP_RS07195		-1.6	-8.6	M20 family metallo-hydrolase
MMP_RS00695		-1.6	-1.7	biotin--[acetyl-CoA-carboxylase] ligase
MMP_RS06895		-1.6	-2.1	selenocysteine-specific translation elongation factor
MMP_RS01325		-1.5	-2.6	dihydroneopterin aldolase family protein
MMP_RS01830		-1.5	-2.1	tRNA-Val
MMP_RS01700		-1.5	-1.4	dihydroxy-acid dehydratase
MMP_RS01610		-1.5	-4.2	hypothetical protein
MMP_RS06930		-1.5	-9.1	MBL fold metallo-hydrolase
MMP_RS04685		-1.5	-3.2	DUF126 domain-containing protein
MMP_RS06730		-1.5	-1.6	phosphopantothenate/pantothenate synthetase
MMP_RS05510		-1.5	-5.0	Rrf2 family transcriptional regulator
MMP_RS01545		-1.5	-1.5	CBS domain-containing protein
MMP_RS05430		-1.4	-4.7	TIGR00288 family NYN domain-containing protein
MMP_RS02135		-1.4	-4.4	DUF5612 domain-containing protein
MMP_RS07545		-1.4	-1.8	HTH domain-containing protein
MMP_RS02165		-1.4	-6.6	tRNA-dihydrouridine synthase
MMP_RS04890		-1.4	-1.1	adenylyltransferase/cytidyltransferase family protein
MMP_RS06200		-1.4	-9.4	M24 family metallopeptidase
MMP_RS06475		-1.4	-3.8	FAD-dependent oxidoreductase
MMP_RS01380		-1.4	-4.5	PHP domain-containing protein
MMP_RS01800		-1.4	-3.1	TIGR00303 family protein
MMP_RS07575		-1.4	-3.4	RNA ligase partner protein
MMP_RS05765		-1.4	-5.7	M42 family metallopeptidase
MMP_RS05540		-1.4	-2.8	hypothetical protein
MMP_RS06340		-1.4	-6.7	phosphoadenosine phosphosulfate reductase family protein
MMP_RS03035		-1.4	-4.3	4-hydroxy-tetrahydrodipicolinate synthase
MMP_RS02900		-1.4	-0.8	imidazoleglycerol-phosphate dehydratase HisB
MMP_RS06175		-1.4	-7.2	winged helix-turn-helix transcriptional regulator
MMP_RS08165		-1.3	-3.5	phosphoglycerate dehydrogenase
MMP_RS00675		-1.3	-1.5	nitroreductase family protein
MMP_RS01385		-1.3	-0.9	imidazole glycerol phosphate synthase subunit HisH
MMP_RS05875		-1.3	-4.7	hydroxyethylthiazole kinase
MMP_RS05815		-1.3	-2.1	NOL1/NOP2/sun family putative RNA methylase
MMP_RS07200		-1.2	-6.0	[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
MMP_RS07365		-1.2	-8.6	2-phosphoglycerate kinase
MMP_RS01075		-1.2	-2.4	hypothetical protein
MMP_RS02190		-1.2	-2.5	sulfopyruvate decarboxylase subunit alpha
MMP_RS04870		-1.2	-5.1	TIGR02253 family HAD-type hydrolase
MMP_RS06925		-1.2	-3.0	ribonuclease VapC4
MMP_RS06230		-1.2	-1.9	helix-turn-helix domain-containing protein
MMP_RS01250		-1.2	-4.8	tRNA (guanine(26)-N(2))-dimethyltransferase
MMP_RS05245		-1.2	-7.1	archaeosine biosynthesis radical SAM protein RaSEA
MMP_RS03205		-1.2	-2.0	peptidyl-tRNA hydrolase Pth2
MMP_RS07685		-1.2	-6.0	TIGR01212 family radical SAM protein
MMP_RS07755		-1.2	-1.7	DUF555 domain-containing protein
MMP_RS08715		-1.2	-1.3	formylmethanofuran dehydrogenase subunit B
MMP_RS02235		-1.1	-5.5	CBS domain-containing protein
MMP_RS01365		-1.1	-2.5	archaeal proteasome endopeptidase complex subunit alpha
MMP_RS06885		-1.1	-2.3	50S ribosome-binding GTPase
MMP_RS00555		-1.1	-3.9	MFS transporter
MMP_RS03475		-1.1	-0.8	hypothetical protein
MMP_RS00290		-1.1	-6.9	hypothetical protein
MMP_RS00050		-1.1	-6.2	AarF/UbiB family protein
MMP_RS00035		-1.1	-6.9	DUF2098 family protein
MMP_RS05500		-1.1	-5.8	2-isopropylmalate synthase
MMP_RS01195		-1.0	-1.3	metalloregulator ArsR/SmtB family transcription factor
MMP_RS06020		-1.0	-4.0	archaeoflavoprotein AfpA
MMP_RS08435		-1.0	-2.3	Era-like GTP-binding protein
MMP_RS05845		-1.0	-2.1	tRNA-intron lyase
MMP_RS00060		-1.0	-2.3	3-dehydroquinate synthase II
MMP_RS07775		-1.0	-3.1	alanine dehydrogenase
MMP_RS07425		-1.0	-5.0	GTP-binding protein
MMP_RS01745		-1.0	-4.5	AMP phosphorylase
MMP_RS04710		-1.0	-1.5	hypothetical protein
MMP_RS01725		-1.0	-3.5	class I SAM-dependent methyltransferase family protein
MMP_RS01720		-1.0	-1.2	replication factor C large subunit
MMP_RS02345		-1.0	-2.4	GTP-dependent dephospho-CoA kinase family protein
MMP_RS02170		-0.9	-3.7	CBS domain-containing protein
MMP_RS03250		-0.9	-2.7	MJ1244 family protein
MMP_RS06865		-0.9	-1.5	HypC/HybG/HupF family hydrogenase formation chaperone
MMP_RS05425		-0.9	-3.5	monovalent cation/H+ antiporter complex subunit F
MMP_RS03400		-0.9	-2.2	archease
MMP_RS05800		-0.9	-5.6	B12-binding domain-containing radical SAM protein
MMP_RS08200		-0.9	-7.2	archaeosine synthase subunit alpha
MMP_RS06120		-0.9	-2.0	UPF0147 family protein
MMP_RS08690		-0.9	-4.1	RNA-guided pseudouridylation complex pseudouridine synthase subunit Cbf5
MMP_RS08940		-0.9	-1.3	MetS family NSS transporter small subunit
MMP_RS03095		-0.9	-5.4	diphthine synthase
MMP_RS07710		-0.8	-3.9	cell division protein FtsZ
MMP_RS08650		-0.8	-2.5	glutamine--fructose-6-phosphate transaminase (isomerizing)
MMP_RS08615		-0.8	-2.1	flagellar protein G
MMP_RS05095		-0.8	-3.3	CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon
MMP_RS08240		-0.8	-3.0	methanogenesis marker 16 metalloprotein
MMP_RS03590		-0.8	-3.2	METTL5 family protein
MMP_RS05345		-0.8	-3.5	hypothetical protein
MMP_RS01665		-0.8	-2.0	DUF2111 domain-containing protein
MMP_RS08320		-0.8	-3.9	molybdopterin molybdotransferase MoeA
MMP_RS03445		-0.8	-0.9	methanogenesis marker 17 protein
MMP_RS05555		-0.7	-0.9	DUF4040 domain-containing protein
MMP_RS00130		-0.7	-1.1	nickel-responsive transcriptional regulator NikR
MMP_RS08675		-0.7	-1.9	class III signal peptide-containing protein
MMP_RS01440		-0.7	-3.3	NAAT family transporter
MMP_RS06870		-0.7	-2.9	DedA family protein
MMP_RS05440		-0.7	-3.9	winged helix-turn-helix transcriptional regulator
MMP_RS05060		-0.7	-5.1	AAA family ATPase
MMP_RS00515		-0.7	-0.8	DUF655 domain-containing protein
MMP_RS05285		-0.7	-2.7	MMPL family transporter
MMP_RS07790		-0.7	-2.9	segregation/condensation protein A
MMP_RS07180		-0.7	-3.7	DEAD/DEAH box helicase
MMP_RS07535		-0.7	-3.8	4Fe-4S binding protein
MMP_RS05545		-0.7	-2.1	pyridoxal phosphate-dependent aminotransferase
MMP_RS03520		-0.7	-1.0	YwbE family protein
MMP_RS00535		-0.7	-2.0	TIGR00375 family protein
MMP_RS06920		-0.7	-4.7	AAA family ATPase
MMP_RS03485		-0.6	-2.2	TIGR00267 family protein
MMP_RS00320		-0.6	-1.4	class I SAM-dependent methyltransferase
MMP_RS01790		-0.6	-2.8	restriction endonuclease
MMP_RS06035		-0.6	-4.8	glycosyltransferase family 2 protein
MMP_RS02605		-0.6	-0.7	MotA/TolQ/ExbB proton channel family protein

Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in nutrient t1 experiments