Experiment set6IT002 for Methanococcus maripaludis S2

Compare to:

formate McAA biotin dropout

200 most important genes:

  gene name fitness t score description  
MMP_RS01020 -6.0 -1.7 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS08300 -5.3 -2.6 metal-sulfur cluster assembly factor compare
MMP_RS01175 -5.0 -11.3 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS06700 -4.8 -18.5 hypothetical protein compare
MMP_RS06680 -4.8 -16.6 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS06355 -4.7 -6.2 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS06685 -4.7 -23.5 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS06350 -4.2 -15.2 HesA/MoeB/ThiF family protein compare
MMP_RS03015 -3.9 -17.1 GTP 3' 8-cyclase MoaA compare
MMP_RS02010 -3.9 -18.6 PHP domain-containing protein compare
MMP_RS06345 -3.8 -15.6 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS05515 -3.8 -7.7 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS02280 -3.7 -2.0 DUF211 domain-containing protein compare
MMP_RS07635 -3.7 -10.6 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS00515 -3.5 -1.9 DUF655 domain-containing protein compare
MMP_RS01985 -3.5 -15.8 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS06715 -3.4 -23.5 cache domain-containing protein compare
MMP_RS04605 -3.3 -6.9 cobalt ECF transporter T component CbiQ compare
MMP_RS08715 -3.2 -2.6 formylmethanofuran dehydrogenase subunit B compare
MMP_RS08820 -3.1 -7.1 hypothetical protein compare
MMP_RS03600 -3.1 -4.4 triose-phosphate isomerase compare
MMP_RS06400 -3.1 -3.0 4Fe-4S binding protein compare
MMP_RS01500 -3.1 -3.7 CBS domain-containing protein compare
MMP_RS06720 -3.0 -14.0 response regulator transcription factor compare
MMP_RS06295 -3.0 -12.6 methanogenesis marker 14 protein compare
MMP_RS08460 -3.0 -4.4 proteasome-activating nucleotidase compare
MMP_RS07005 -2.9 -1.4 4Fe-4S binding protein compare
MMP_RS00040 -2.9 -6.9 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS09020 -2.9 -2.4 hypothetical protein compare
MMP_RS06630 -2.9 -2.2 UPF0058 family protein compare
MMP_RS00895 -2.8 -8.8 hypothetical protein compare
MMP_RS01005 -2.8 -2.8 riboflavin synthase compare
MMP_RS04500 -2.7 -18.1 adenosylmethionine--8-amino-7-oxononanoate transaminase compare
MMP_RS06625 -2.7 -3.9 DNA primase compare
MMP_RS04900 -2.7 -20.5 hypothetical protein compare
MMP_RS02195 -2.7 -6.6 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS03315 -2.7 -2.3 ferrous iron transport protein A compare
MMP_RS01220 -2.7 -13.1 hypothetical protein compare
MMP_RS00300 -2.6 -1.7 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS02240 -2.6 -5.1 methanogenesis marker 7 protein compare
MMP_RS03025 -2.6 -6.3 molybdenum cofactor guanylyltransferase compare
MMP_RS00695 -2.6 -2.4 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS08635 -2.6 -3.7 UbiA family prenyltransferase compare
MMP_RS03445 -2.6 -2.1 methanogenesis marker 17 protein compare
MMP_RS03435 -2.5 -3.5 ketol-acid reductoisomerase compare
MMP_RS04780 -2.5 -5.0 ribonuclease P compare
MMP_RS04585 -2.5 -12.1 AIR synthase related protein compare
MMP_RS06370 -2.5 -8.3 biotin synthase BioB compare
MMP_RS06705 -2.5 -9.7 formate/nitrite transporter family protein compare
MMP_RS07845 -2.5 -4.8 LL-diaminopimelate aminotransferase compare
MMP_RS07445 -2.5 -6.4 helix-turn-helix domain-containing protein compare
MMP_RS00115 -2.5 -16.5 radical SAM protein compare
MMP_RS04890 -2.4 -1.4 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS01545 -2.4 -2.2 CBS domain-containing protein compare
MMP_RS07630 -2.3 -2.7 ATP-binding cassette domain-containing protein compare
MMP_RS01225 -2.3 -8.4 DUF5379 domain-containing protein compare
MMP_RS00685 -2.3 -7.0 2-phospho-L-lactate guanylyltransferase compare
MMP_RS02340 -2.3 -3.5 DNA-directed RNA polymerase subunit E'' compare
MMP_RS07380 -2.3 -2.5 transcription elongation factor Spt5 compare
MMP_RS04775 -2.3 -5.6 adenosylhomocysteinase compare
MMP_RS08100 -2.3 -11.0 8-amino-7-oxononanoate synthase compare
MMP_RS04615 -2.3 -6.7 PDGLE domain-containing protein compare
MMP_RS08105 -2.2 -11.2 6-carboxyhexanoate--CoA ligase compare
MMP_RS01265 -2.2 -2.5 hypothetical protein compare
MMP_RS01800 -2.2 -4.5 TIGR00303 family protein compare
MMP_RS06885 -2.2 -4.9 50S ribosome-binding GTPase compare
MMP_RS04620 -2.2 -12.2 cobalt transporter CbiM compare
MMP_RS07600 -2.2 -5.4 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS02355 -2.2 -5.5 30S ribosomal protein S27ae compare
MMP_RS06285 -2.2 -4.8 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS08095 -2.2 -10.3 dethiobiotin synthase compare
MMP_RS07545 -2.2 -2.3 HTH domain-containing protein compare
MMP_RS08435 -2.1 -4.6 Era-like GTP-binding protein compare
MMP_RS07525 -2.1 -11.9 4Fe-4S binding protein compare
MMP_RS06105 -2.1 -9.8 hydrogenase maturation peptidase HycI compare
MMP_RS01610 -2.1 -6.1 hypothetical protein compare
MMP_RS01755 -2.1 -2.4 DUF2097 domain-containing protein compare
MMP_RS08720 -2.1 -2.0 4Fe-4S binding protein compare
MMP_RS08745 -2.1 -5.9 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS00110 -2.1 -5.3 hypothetical protein compare
MMP_RS02800 -2.0 -7.0 nucleotidyltransferase domain-containing protein compare
MMP_RS07605 -2.0 -3.8 diadenylate cyclase compare
MMP_RS01385 -2.0 -1.3 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS06975 -2.0 -3.9 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS07645 -2.0 -10.1 aldehyde dehydrogenase family protein compare
MMP_RS08210 -2.0 -3.6 phosphatidylglycerophosphatase A compare
MMP_RS06215 -2.0 -4.1 30S ribosomal protein S6e compare
MMP_RS00295 -2.0 -4.7 gamma carbonic anhydrase family protein compare
MMP_RS01980 -2.0 -13.9 trimeric intracellular cation channel family protein compare
MMP_RS08645 -1.9 -8.9 UPF0179 family protein compare
MMP_RS06230 -1.9 -3.0 helix-turn-helix domain-containing protein compare
MMP_RS01830 -1.8 -3.4 tRNA-Val compare
MMP_RS06475 -1.8 -6.5 FAD-dependent oxidoreductase compare
MMP_RS01795 -1.8 -1.6 methanogenesis marker 6 protein compare
MMP_RS07730 -1.8 -2.6 pyruvate synthase subunit beta compare
MMP_RS06270 -1.8 -7.4 TIGR00300 family protein compare
MMP_RS07195 -1.8 -10.4 M20 family metallo-hydrolase compare
MMP_RS03640 -1.8 -4.7 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS02165 -1.7 -9.4 tRNA-dihydrouridine synthase compare
MMP_RS06020 -1.7 -6.0 archaeoflavoprotein AfpA compare
MMP_RS07365 -1.7 -11.1 2-phosphoglycerate kinase compare
MMP_RS04685 -1.7 -3.8 DUF126 domain-containing protein compare
MMP_RS03035 -1.7 -4.8 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS03580 -1.7 -4.9 signal recognition particle-docking protein FtsY compare
MMP_RS05845 -1.6 -1.8 tRNA-intron lyase compare
MMP_RS04870 -1.6 -5.9 TIGR02253 family HAD-type hydrolase compare
MMP_RS00620 -1.6 -10.2 4Fe-4S binding protein compare
MMP_RS05245 -1.6 -9.6 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS05765 -1.6 -9.4 M42 family metallopeptidase compare
MMP_RS08650 -1.6 -3.7 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS05540 -1.6 -3.3 hypothetical protein compare
MMP_RS01380 -1.6 -5.8 PHP domain-containing protein compare
MMP_RS02235 -1.5 -8.6 CBS domain-containing protein compare
MMP_RS04710 -1.5 -2.7 hypothetical protein compare
MMP_RS06865 -1.5 -1.4 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS01725 -1.5 -4.6 class I SAM-dependent methyltransferase family protein compare
MMP_RS07735 -1.5 -1.5 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS05430 -1.4 -5.5 TIGR00288 family NYN domain-containing protein compare
MMP_RS03400 -1.4 -3.3 archease compare
MMP_RS02345 -1.4 -3.5 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS02190 -1.4 -3.1 sulfopyruvate decarboxylase subunit alpha compare
MMP_RS00060 -1.4 -2.8 3-dehydroquinate synthase II compare
MMP_RS06120 -1.4 -2.5 UPF0147 family protein compare
MMP_RS06200 -1.3 -8.6 M24 family metallopeptidase compare
MMP_RS06340 -1.3 -8.2 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS01700 -1.3 -1.5 dihydroxy-acid dehydratase compare
MMP_RS00305 -1.3 -2.4 phosphoribosyl-ATP diphosphatase compare
MMP_RS01325 -1.3 -3.2 dihydroneopterin aldolase family protein compare
MMP_RS02145 -1.3 -7.6 winged helix-turn-helix transcriptional regulator compare
MMP_RS06930 -1.3 -7.9 MBL fold metallo-hydrolase compare
MMP_RS07575 -1.3 -3.7 RNA ligase partner protein compare
MMP_RS07765 -1.3 -7.3 sodium:alanine symporter family protein compare
MMP_RS08320 -1.3 -6.7 molybdopterin molybdotransferase MoeA compare
MMP_RS05875 -1.3 -4.4 hydroxyethylthiazole kinase compare
MMP_RS01365 -1.3 -4.0 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS06175 -1.3 -6.5 winged helix-turn-helix transcriptional regulator compare
MMP_RS07200 -1.2 -5.5 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS03485 -1.2 -4.5 TIGR00267 family protein compare
MMP_RS00050 -1.2 -7.1 AarF/UbiB family protein compare
MMP_RS08790 -1.2 -2.7 translation initiation factor IF-2 subunit alpha compare
MMP_RS03960 -1.2 -1.5 hypothetical protein compare
MMP_RS07685 -1.2 -5.5 TIGR01212 family radical SAM protein compare
MMP_RS05920 -1.2 -0.8 50S ribosomal protein L37e compare
MMP_RS03205 -1.1 -2.1 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS07755 -1.1 -1.9 DUF555 domain-containing protein compare
MMP_RS07750 -1.1 -4.7 DUF357 domain-containing protein compare
MMP_RS02135 -1.1 -2.3 DUF5612 domain-containing protein compare
MMP_RS05345 -1.1 -5.0 hypothetical protein compare
MMP_RS06895 -1.1 -1.9 selenocysteine-specific translation elongation factor compare
MMP_RS05510 -1.1 -5.2 Rrf2 family transcriptional regulator compare
MMP_RS03475 -1.1 -0.8 hypothetical protein compare
MMP_RS02930 -1.1 -2.3 class I SAM-dependent methyltransferase compare
MMP_RS01250 -1.1 -3.4 tRNA (guanine(26)-N(2))-dimethyltransferase compare
MMP_RS07860 -1.0 -1.2 hypothetical protein compare
MMP_RS08165 -1.0 -2.4 phosphoglycerate dehydrogenase compare
MMP_RS07425 -1.0 -4.8 GTP-binding protein compare
MMP_RS01180 -1.0 -1.9 XTP/dITP diphosphatase compare
MMP_RS03465 -1.0 -1.7 adenine phosphoribosyltransferase compare
MMP_RS02245 -1.0 -3.1 hypothetical protein compare
MMP_RS07710 -1.0 -4.5 cell division protein FtsZ compare
MMP_RS05425 -1.0 -3.5 monovalent cation/H+ antiporter complex subunit F compare
MMP_RS03155 -1.0 -4.6 precorrin-6A reductase compare
MMP_RS06925 -0.9 -2.4 ribonuclease VapC4 compare
MMP_RS03520 -0.9 -1.6 YwbE family protein compare
MMP_RS03590 -0.9 -4.4 METTL5 family protein compare
MMP_RS03095 -0.9 -6.5 diphthine synthase compare
MMP_RS05250 -0.9 -1.0 NFYB/HAP3 family transcription factor subunit compare
MMP_RS08200 -0.9 -7.5 archaeosine synthase subunit alpha compare
MMP_RS04695 -0.9 -4.6 selenide water dikinase SelD compare
MMP_RS03305 -0.9 -3.8 winged helix-turn-helix domain-containing protein compare
MMP_RS07090 -0.9 -5.1 tRNA (adenine-N1)-methyltransferase compare
MMP_RS02175 -0.9 -0.9 DUF1611 domain-containing protein compare
MMP_RS00290 -0.8 -5.4 hypothetical protein compare
MMP_RS07435 -0.8 -1.3 GMP synthase subunit A compare
MMP_RS00985 -0.8 -4.2 CDC48 family AAA ATPase compare
MMP_RS01840 -0.8 -4.9 TIGR00289 family protein compare
MMP_RS03300 -0.8 -1.1 TOBE domain-containing protein compare
MMP_RS04720 -0.8 -2.1 DedA family protein compare
MMP_RS03250 -0.8 -3.0 MJ1244 family protein compare
MMP_RS07580 -0.8 -1.5 DUF356 domain-containing protein compare
MMP_RS00675 -0.8 -1.1 nitroreductase family protein compare
MMP_RS05815 -0.8 -1.5 NOL1/NOP2/sun family putative RNA methylase compare
MMP_RS08690 -0.8 -4.9 RNA-guided pseudouridylation complex pseudouridine synthase subunit Cbf5 compare
MMP_RS00915 -0.8 -3.9 DUF116 domain-containing protein compare
MMP_RS08445 -0.8 -2.7 DUF2099 family protein compare
MMP_RS02605 -0.8 -1.0 MotA/TolQ/ExbB proton channel family protein compare
MMP_RS02885 -0.8 -5.8 molybdopterin biosynthesis protein compare
MMP_RS00555 -0.7 -2.8 MFS transporter compare
MMP_RS06905 -0.7 -2.1 hypothetical protein compare
MMP_RS06730 -0.7 -0.9 phosphopantothenate/pantothenate synthetase compare
MMP_RS05500 -0.7 -4.9 2-isopropylmalate synthase compare
MMP_RS05800 -0.7 -4.6 B12-binding domain-containing radical SAM protein compare
MMP_RS03210 -0.7 -5.5 tRNA guanosine(15) transglycosylase TgtA compare
MMP_RS00850 -0.7 -3.9 TIGR01177 family methyltransferase compare
MMP_RS00810 -0.7 -3.8 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS07385 -0.7 -1.2 protein translocase SEC61 complex subunit gamma compare
MMP_RS06130 -0.7 -1.6 peptidylprolyl isomerase compare
MMP_RS03080 -0.7 -2.5 universal stress protein compare
MMP_RS07775 -0.7 -3.8 alanine dehydrogenase compare
MMP_RS03700 -0.7 -3.9 sodium:proton antiporter compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in nutrient t1 experiments