Experiment set6H41 for Pseudomonas stutzeri RCH2

Compare to:

RCH2 defined media with Sodium Chlorate 40 mM

200 most detrimental genes:

  gene name fitness t score description  
Psest_3168 +8.7 37.0 Molybdopterin converting factor, large subunit compare
Psest_3484 +8.4 28.5 nitrate reductase molybdenum cofactor assembly chaperone compare
Psest_3170 +8.4 49.3 molybdenum cofactor biosynthesis protein MoaC compare
Psest_1961 +8.3 66.9 molybdopterin-guanine dinucleotide biosynthesis protein A, proteobacterial compare
Psest_3480 +8.3 8.6 molybdenum cofactor biosynthesis protein B, proteobacterial compare
Psest_3486 +8.2 74.1 respiratory nitrate reductase, alpha subunit compare
Psest_3485 +8.2 60.9 nitrate reductase, beta subunit compare
Psest_3479 +7.7 29.8 molybdenum cofactor synthesis domain compare
Psest_3483 +7.5 33.5 respiratory nitrate reductase, gamma subunit compare
Psest_1805 +6.6 18.5 integration host factor, beta subunit compare
Psest_1974 +6.4 28.8 integration host factor, alpha subunit compare
Psest_3000 +4.8 27.1 molybdate ABC transporter, permease protein compare
Psest_2999 +4.7 20.9 molybdenum ABC transporter, periplasmic molybdate-binding protein compare
Psest_1292 +4.6 36.4 monothiol glutaredoxin, Grx4 family compare
Psest_0959 +4.5 23.4 Uncharacterized protein conserved in bacteria compare
Psest_0296 +4.5 32.0 glutathione synthetase, prokaryotic compare
Psest_3489 +4.5 10.2 hypothetical protein compare
Psest_3001 +4.4 14.4 molybdenum ABC transporter, ATP-binding protein compare
Psest_3301 +4.4 13.2 Predicted transcriptional regulator, BolA superfamily compare
Psest_3490 +4.4 5.5 Signal transduction histidine kinase, nitrate/nitrite-specific compare
Psest_3487 +3.8 13.6 Nitrate/nitrite transporter compare
Psest_3117 +3.8 20.8 electron transport complex, RnfABCDGE type, E subunit compare
Psest_1840 +3.7 32.5 Undecaprenyl-phosphate glucose phosphotransferase compare
Psest_3115 +3.7 29.3 electron transport complex, RnfABCDGE type, D subunit compare
Psest_3114 +3.6 23.0 electron transport complex, RnfABCDGE type, C subunit compare
Psest_3113 +3.6 17.4 electron transport complex, RnfABCDGE type, B subunit compare
Psest_2232 +3.5 29.6 UTP-glucose-1-phosphate uridylyltransferase compare
Psest_3112 +3.5 19.8 electron transport complex, RnfABCDGE type, A subunit compare
Psest_2358 +3.3 2.6 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) compare
Psest_2538 +3.2 8.3 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases compare
Psest_3174 +2.8 25.2 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase compare
Psest_3488 +2.7 10.5 Universal stress protein UspA and related nucleotide-binding proteins compare
Psest_2066 +2.7 2.5 ABC-type uncharacterized transport system, permease component compare
Psest_0401 +2.4 2.0 isopentenyl-diphosphate delta-isomerase, type 2 compare
Psest_1837 +2.4 16.9 Endoglucanase compare
Psest_0089 +2.3 7.9 phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN compare
Psest_0999 +2.2 8.2 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_1204 +2.1 5.2 Transcriptional regulators compare
Psest_0993 +2.1 15.6 Glucose-6-phosphate isomerase compare
Psest_2712 +2.0 9.9 Surface lipoprotein compare
Psest_3998 +2.0 11.7 glutamate--cysteine ligase compare
Psest_3116 +1.8 5.0 electron transport complex, RnfABCDGE type, G subunit compare
Psest_2104 +1.8 8.3 IscR-regulated protein YhgI compare
Psest_1518 +1.8 4.1 tRNA_Ser_CGA compare
Psest_4239 +1.7 10.9 Cytochrome b compare
Psest_3910 +1.7 2.3 Uncharacterized protein conserved in bacteria compare
Psest_3304 +1.7 9.4 ABC-type transport system involved in resistance to organic solvents, auxiliary component compare
Psest_3481 +1.7 5.7 molybdenum cofactor biosynthesis protein A, bacterial conserved
Psest_0417 +1.7 5.8 Acyl-CoA dehydrogenases compare
Psest_0144 +1.7 9.0 Fe-S cluster protector protein compare
Psest_3306 +1.6 7.1 conserved hypothetical integral membrane protein compare
Psest_0498 +1.6 2.9 ribosome small subunit-dependent GTPase A compare
Psest_3303 +1.6 7.0 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) compare
Psest_4303 +1.6 1.9 HEAT repeat. compare
Psest_3883 +1.6 6.9 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_1819 +1.6 14.1 Nucleoside-diphosphate-sugar epimerases compare
Psest_3307 +1.6 10.1 ABC-type transport system involved in resistance to organic solvents, ATPase component compare
Psest_3216 +1.5 14.1 diguanylate cyclase (GGDEF) domain compare
Psest_3877 +1.5 8.2 Predicted membrane protein compare
Psest_3938 +1.5 3.7 Uncharacterized protein conserved in bacteria compare
Psest_3762 +1.5 5.7 iron donor protein CyaY compare
Psest_2447 +1.5 1.9 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) compare
Psest_1313 +1.4 3.4 Uncharacterized conserved small protein compare
Psest_3697 +1.4 1.3 Outer membrane lipoprotein carrier protein LolA. compare
Psest_0461 +1.4 10.1 Glycosyltransferase involved in LPS biosynthesis compare
Psest_3305 +1.4 10.5 ABC-type transport system involved in resistance to organic solvents, periplasmic component compare
Psest_1810 +1.4 12.3 UDP-N-acetylglucosamine 4,6-dehydratase compare
Psest_0462 +1.4 13.6 Lipid A core - O-antigen ligase and related enzymes compare
Psest_2015 +1.4 2.2 Type II secretory pathway, component PulD compare
Psest_0717 +1.4 10.9 Protein of unknown function (DUF1631). compare
Psest_4008 +1.4 11.1 PAS domain S-box compare
Psest_0368 +1.4 1.5 Transcriptional regulator compare
Psest_3664 +1.3 1.4 Predicted phosphotransferase related to Ser/Thr protein kinases compare
Psest_0309 +1.3 1.7 RND family efflux transporter, MFP subunit compare
Psest_0378 +1.3 1.7 Lactate dehydrogenase and related dehydrogenases compare
Psest_4315 +1.3 2.4 ABC-type metal ion transport system, permease component compare
Psest_3217 +1.3 12.2 PAS domain S-box compare
Psest_1079 +1.3 3.8 Isopropylmalate/homocitrate/citramalate synthases compare
Psest_3482 +1.3 4.1 Parvulin-like peptidyl-prolyl isomerase compare
Psest_3492 +1.3 3.1 hypothetical protein compare
Psest_3881 +1.2 1.8 hypothetical protein compare
Psest_1817 +1.2 7.7 hypothetical protein compare
Psest_1910 +1.2 2.7 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase compare
Psest_3447 +1.2 1.1 Uncharacterized MobA-related protein compare
Psest_0091 +1.1 3.5 phosphonate C-P lyase system protein PhnL compare
Psest_0243 +1.1 1.0 hypothetical protein compare
Psest_1825 +1.1 8.3 Predicted nucleoside-diphosphate sugar epimerases compare
Psest_1818 +1.1 8.7 GDP-mannose 4,6-dehydratase compare
Psest_1816 +1.1 5.4 hypothetical protein compare
Psest_0355 +1.1 2.5 Glycine cleavage system regulatory protein compare
Psest_1206 +1.1 2.0 ABC-type Mn2+/Zn2+ transport systems, permease components compare
Psest_2434 +1.1 1.6 Protein of unknown function (DUF2892). compare
Psest_3064 +1.1 1.6 hypothetical protein compare
Psest_0094 +1.1 1.7 Uncharacterized enzyme of phosphonate metabolism compare
Psest_1053 +1.1 2.2 hypothetical protein compare
Psest_1823 +1.1 8.1 Nucleoside-diphosphate-sugar epimerases compare
Psest_3990 +1.1 6.4 PAP2 superfamily. compare
Psest_0568 +1.1 2.8 pseudouridine synthase compare
Psest_4211 +1.1 2.2 conserverd hypothetical protein compare
Psest_0212 +1.1 1.3 exodeoxyribonuclease V, gamma subunit compare
Psest_3780 +1.0 2.6 Transcriptional regulator compare
Psest_2911 +1.0 1.6 Protein of unknown function (DUF2945). compare
Psest_3731 +1.0 8.6 exopolyphosphatase compare
Psest_3413 +1.0 3.3 hypothetical protein compare
Psest_2645 +1.0 5.9 Transcriptional regulator compare
Psest_3012 +1.0 2.3 cob(II)yrinic acid a,c-diamide reductase compare
Psest_1511 +1.0 3.5 Predicted redox protein, regulator of disulfide bond formation compare
Psest_2621 +1.0 3.3 TadE-like protein. compare
Psest_4258 +1.0 2.6 ABC-type uncharacterized transport system, auxiliary component compare
Psest_3637 +1.0 2.7 Predicted molecular chaperone distantly related to HSP70-fold metalloproteases compare
Psest_4276 +1.0 2.1 hypothetical protein compare
Psest_4201 +1.0 1.4 general secretion pathway protein F compare
Psest_0459 +1.0 7.3 Predicted carbamoyl transferase, NodU family compare
Psest_1249 +1.0 5.7 serine O-acetyltransferase compare
Psest_2134 +1.0 7.7 amino acid carrier protein compare
Psest_3893 +1.0 2.9 Multisubunit Na+/H+ antiporter, MnhE subunit compare
Psest_0716 +1.0 2.3 Protein of unknown function (DUF3094). compare
Psest_3670 +0.9 7.2 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) compare
Psest_1227 +0.9 1.8 Predicted SAM-dependent methyltransferase compare
Psest_4128 +0.9 1.6 Universal stress protein UspA and related nucleotide-binding proteins compare
Psest_1994 +0.9 3.4 Amidases related to nicotinamidase compare
Psest_3458 +0.9 1.7 hypothetical protein compare
Psest_0103 +0.9 1.8 triphosphoribosyl-dephospho-CoA synthase MdcB compare
Psest_1849 +0.9 2.7 Predicted glutamine amidotransferase compare
Psest_3827 +0.9 2.1 Transcriptional regulator compare
Psest_1230 +0.9 1.8 Uncharacterized protein conserved in bacteria compare
Psest_0532 +0.9 4.9 tRNA-N(6)-(isopentenyl)adenosine-37 thiotransferase enzyme MiaB compare
Psest_1986 +0.9 2.1 3-phosphoshikimate 1-carboxyvinyltransferase compare
Psest_0851 +0.9 6.1 Transcriptional regulators compare
Psest_3555 +0.9 1.8 Predicted methyltransferase compare
Psest_0204 +0.9 2.9 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_4168 +0.9 2.6 Flagellar FliJ protein. compare
Psest_1000 +0.9 6.3 PAS domain S-box compare
Psest_0661 +0.9 2.3 PAS domain S-box compare
Psest_3882 +0.8 5.5 Opacity protein and related surface antigens compare
Psest_4314 +0.8 2.7 ABC-type metal ion transport system, ATPase component compare
Psest_2945 +0.8 1.4 septum site-determining protein MinC compare
Psest_2980 +0.8 6.6 oxaloacetate decarboxylase alpha subunit compare
Psest_1809 +0.8 6.5 Membrane protein involved in the export of O-antigen and teichoic acid compare
Psest_0310 +0.8 2.5 The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family compare
Psest_0093 +0.8 1.4 Uncharacterized enzyme of phosphonate metabolism compare
Psest_3991 +0.8 1.9 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) compare
Psest_0678 +0.8 1.7 yjeF C-terminal region, hydroxyethylthiazole kinase-related/yjeF N-terminal region compare
Psest_3832 +0.8 1.3 hypothetical protein compare
Psest_3995 +0.8 1.3 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_4137 +0.8 3.5 Uncharacterized iron-regulated membrane protein compare
Psest_1489 +0.8 2.8 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases compare
Psest_4309 +0.8 2.8 ABC-type Mn/Zn transport systems, ATPase component compare
Psest_4364 +0.8 3.1 16S rRNA (guanine(527)-N(7))-methyltransferase GidB compare
Psest_2407 +0.8 2.0 nitrite reductase [NAD(P)H], small subunit compare
Psest_1187 +0.8 5.1 exodeoxyribonuclease III compare
Psest_2976 +0.8 1.6 hypothetical protein compare
Psest_0675 +0.8 1.9 Predicted periplasmic lipoprotein compare
Psest_0215 +0.8 2.7 hypothetical protein compare
Psest_1822 +0.8 5.1 Glycosyltransferases involved in cell wall biogenesis compare
Psest_4293 +0.8 5.6 PAS domain S-box/diguanylate cyclase (GGDEF) domain compare
Psest_1741 +0.8 2.3 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_1457 +0.8 1.7 FOG: Ankyrin repeat compare
Psest_0119 +0.8 1.7 hypothetical protein compare
Psest_4371 +0.8 2.4 Multisubunit Na+/H+ antiporter, MnhB subunit compare
Psest_3146 +0.8 1.7 hypothetical protein compare
Psest_3275 +0.8 3.8 Stringent starvation protein B compare
Psest_1248 +0.8 3.9 RNA methyltransferase, TrmH family, group 1 compare
Psest_3884 +0.8 0.6 Signal transduction histidine kinase compare
Psest_3787 +0.8 2.9 Domain of Unknown Function (DUF1080). compare
Psest_2551 +0.8 5.2 1-aminocyclopropane-1-carboxylate deaminase compare
Psest_3692 +0.8 1.5 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases compare
Psest_3712 +0.7 3.8 Type II secretory pathway, component ExeA (predicted ATPase) compare
Psest_2489 +0.7 4.8 branched-chain amino acid uptake carrier compare
Psest_4134 +0.7 1.4 Uncharacterized protein conserved in bacteria compare
Psest_0100 +0.7 1.5 phosphonate ABC transporter, ATP-binding protein compare
Psest_2950 +0.7 1.6 putative NAD(P)H quinone oxidoreductase, PIG3 family compare
Psest_2849 +0.7 4.5 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit compare
Psest_3926 +0.7 5.4 GTP-binding protein TypA/BipA compare
Psest_1506 +0.7 3.1 queuosine biosynthesis protein QueC compare
Psest_2878 +0.7 3.4 conserved hypothetical protein compare
Psest_2072 +0.7 3.7 Methyltransferase domain. compare
Psest_2964 +0.7 2.7 flagellar basal-body rod protein FlgF compare
Psest_3236 +0.7 1.3 hypothetical protein compare
Psest_2962 +0.7 4.5 Flagellar basal body L-ring protein compare
Psest_2764 +0.7 1.1 hypothetical protein compare
Psest_3143 +0.7 3.5 Uncharacterized protein conserved in bacteria compare
Psest_4405 +0.7 1.5 hypothetical protein compare
Psest_1428 +0.7 1.3 Threonine dehydrogenase and related Zn-dependent dehydrogenases compare
Psest_3698 +0.7 1.8 Predicted exporter compare
Psest_4004 +0.7 1.0 Uncharacterized conserved protein compare
Psest_3185 +0.7 1.5 MoxR-like ATPases compare
Psest_0198 +0.7 3.8 TRAP transporter solute receptor, TAXI family compare
Psest_3699 +0.7 2.4 Dehydrogenases (flavoproteins) compare
Psest_2285 +0.7 2.1 ATP-dependent protease La compare
Psest_0402 +0.7 1.0 glycosyltransferase, MGT family compare
Psest_4135 +0.7 2.6 Ketosteroid isomerase homolog compare
Psest_2963 +0.7 4.8 flagellar basal-body rod protein FlgG, Gram-negative bacteria compare
Psest_2720 +0.7 2.1 Enoyl-CoA hydratase/carnithine racemase compare
Psest_3865 +0.7 2.4 Predicted integral membrane protein (DUF2269). compare
Psest_2971 +0.7 3.2 flagella basal body P-ring formation protein FlgA compare
Psest_0382 +0.7 4.5 Uncharacterized iron-regulated membrane protein compare
Psest_0584 +0.7 2.9 hypothetical protein compare
Psest_3996 +0.7 3.3 Transcriptional accessory protein compare
Psest_2966 +0.7 4.1 Flagellar hook capping protein compare


Specific Phenotypes

For 12 genes in this experiment

For stress Sodium Chlorate in Pseudomonas stutzeri RCH2

For stress Sodium Chlorate across organisms