Experiment set6H35 for Pseudomonas stutzeri RCH2

Compare to:

RCH2 defined media with Cisplatin 0.0002 mg/ml

200 most detrimental genes:

  gene name fitness t score description  
Psest_0401 +3.0 3.2 isopentenyl-diphosphate delta-isomerase, type 2 compare
Psest_0538 +2.3 22.4 Signal transduction histidine kinase compare
Psest_1635 +2.2 20.8 Signal transduction histidine kinase compare
Psest_3884 +2.1 2.6 Signal transduction histidine kinase compare
Psest_1840 +1.6 15.0 Undecaprenyl-phosphate glucose phosphotransferase compare
Psest_1122 +1.5 13.2 putative adhesin (DUF1302) (from data) compare
Psest_3372 +1.4 10.4 Tfp pilus assembly protein PilW compare
Psest_2260 +1.4 9.3 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain compare
Psest_1923 +1.4 5.4 adhesin-associated BNR repeat protein (from data) compare
Psest_1924 +1.4 11.9 adhesin-associated MmpL efflux pump (from data) compare
Psest_3371 +1.3 8.3 type IV pilus modification protein PilV compare
Psest_1567 +1.3 6.8 Transcriptional regulator compare
Psest_3100 +1.2 10.3 RNA polymerase sigma factor RpoE compare
Psest_3816 +1.2 2.7 DNA-directed RNA polymerase, omega subunit compare
Psest_3373 +1.2 7.0 Tfp pilus assembly protein PilX compare
Psest_1725 +1.2 9.1 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_4201 +1.2 2.4 general secretion pathway protein F compare
Psest_2066 +1.1 1.2 ABC-type uncharacterized transport system, permease component compare
Psest_1313 +1.1 2.9 Uncharacterized conserved small protein compare
Psest_2865 +1.1 7.9 Predicted permease, DMT superfamily conserved
Psest_0487 +1.1 4.1 Uncharacterized protein conserved in bacteria compare
Psest_2775 +1.1 6.4 Glycerol-3-phosphate dehydrogenase compare
Psest_0717 +1.0 9.3 Protein of unknown function (DUF1631). compare
Psest_3370 +1.0 5.6 prepilin-type N-terminal cleavage/methylation domain compare
Psest_1888 +1.0 1.6 Sua5/YciO/YrdC/YwlC family protein compare
Psest_3374 +1.0 7.8 Tfp pilus assembly protein, tip-associated adhesin PilY1 compare
Psest_3749 +1.0 7.5 Response regulator of the LytR/AlgR family compare
Psest_2415 +1.0 3.4 TolQ protein compare
Psest_1657 +1.0 2.8 NADH:ubiquinone oxidoreductase, Na(+)-translocating, C subunit compare
Psest_0368 +1.0 1.4 Transcriptional regulator compare
Psest_3296 +1.0 4.3 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain compare
Psest_2136 +1.0 8.1 Predicted homoserine dehydrogenase compare
Psest_3317 +1.0 4.8 Phosphotransferase System HPr (HPr) Family compare
Psest_1602 +0.9 1.3 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_4103 +0.9 1.8 AraC-type DNA-binding domain-containing proteins compare
Psest_0693 +0.9 8.4 His Kinase A (phosphoacceptor) domain./PAS fold./Response regulator receiver domain./Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. compare
Psest_1819 +0.9 8.2 Nucleoside-diphosphate-sugar epimerases compare
Psest_3480 +0.9 1.0 molybdenum cofactor biosynthesis protein B, proteobacterial compare
Psest_0164 +0.9 1.0 Glutaredoxin, GrxC family compare
Psest_3216 +0.9 8.3 diguanylate cyclase (GGDEF) domain compare
Psest_3217 +0.9 8.3 PAS domain S-box compare
Psest_4273 +0.8 6.1 Lysophospholipase compare
Psest_1910 +0.8 2.4 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase compare
Psest_0089 +0.8 2.5 phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN compare
Psest_4052 +0.8 2.3 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component compare
Psest_1457 +0.8 2.3 FOG: Ankyrin repeat compare
Psest_3377 +0.8 1.4 FKBP-type peptidyl-prolyl cis-trans isomerases 2 compare
Psest_3862 +0.8 7.0 phosphoenolpyruvate-protein phosphotransferase compare
Psest_0779 +0.8 2.4 tyrosine aminotransferase (EC 2.6.1.57) (from data) compare
Psest_4072 +0.8 6.1 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II compare
Psest_3481 +0.8 3.8 molybdenum cofactor biosynthesis protein A, bacterial compare
Psest_4008 +0.8 6.4 PAS domain S-box compare
Psest_2344 +0.7 1.9 Methyl-accepting chemotaxis protein compare
Psest_3883 +0.7 4.3 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_2855 +0.7 1.8 Outer membrane protein and related peptidoglycan-associated (lipo)proteins compare
Psest_1741 +0.7 2.1 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_3881 +0.7 1.2 hypothetical protein compare
Psest_0740 +0.7 1.8 Transcriptional regulator compare
Psest_1656 +0.7 2.1 NADH:ubiquinone oxidoreductase, Na(+)-translocating, B subunit compare
Psest_1734 +0.7 3.8 flagellar biosynthetic protein FliR compare
Psest_0031 +0.7 1.2 Uncharacterized conserved protein compare
Psest_3002 +0.7 1.1 Putative translation initiation inhibitor, yjgF family compare
Psest_3839 +0.7 2.8 D-lactate/glycolate dehydrogenase, iron-sulfur subunit GlcF (EC 1.1.99.6; EC 1.1.99.14) (from data) compare
Psest_0417 +0.7 2.8 Acyl-CoA dehydrogenases compare
Psest_0655 +0.6 1.5 Chemotaxis signal transduction protein compare
Psest_4241 +0.6 2.3 hypothetical protein compare
Psest_0346 +0.6 2.0 small component of pyruvate/D-alanine transporter (TIGR03647) (from data) compare
Psest_4293 +0.6 4.7 PAS domain S-box/diguanylate cyclase (GGDEF) domain compare
Psest_4145 +0.6 1.7 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) compare
Psest_2383 +0.6 3.7 Predicted transcriptional regulators compare
Psest_2764 +0.6 1.0 hypothetical protein compare
Psest_0853 +0.6 1.6 6-phosphogluconolactonase compare
Psest_4071 +0.6 4.2 4-hydroxyphenylpyruvate dioxygenase and related hemolysins compare
Psest_1303 +0.6 2.5 hypothetical protein compare
Psest_2551 +0.6 4.3 1-aminocyclopropane-1-carboxylate deaminase compare
Psest_2293 +0.6 1.5 hypothetical protein compare
Psest_3895 +0.6 1.6 hypothetical protein compare
Psest_1317 +0.6 2.4 phosphonate ABC transporter, permease protein PhnE compare
Psest_2798 +0.6 2.0 Truncated hemoglobins compare
Psest_1123 +0.6 5.0 adhesin-associated sorting protein (DUF1329) (from data) compare
Psest_2950 +0.6 3.7 putative NAD(P)H quinone oxidoreductase, PIG3 family compare
Psest_0799 +0.6 2.0 Uncharacterized protein involved in response to NO compare
Psest_2980 +0.6 5.0 oxaloacetate decarboxylase alpha subunit compare
Psest_2025 +0.6 1.3 cold shock domain protein CspD compare
Psest_2793 +0.6 2.5 hypothetical protein compare
Psest_2911 +0.6 1.6 Protein of unknown function (DUF2945). compare
Psest_1731 +0.6 2.0 flagellar biosynthetic protein FliO compare
Psest_0355 +0.6 1.0 Glycine cleavage system regulatory protein compare
Psest_1659 +0.6 2.3 NADH:ubiquinone oxidoreductase, Na(+)-translocating, E subunit compare
Psest_1661 +0.6 2.0 Membrane-associated lipoprotein involved in thiamine biosynthesis compare
Psest_0446 +0.6 3.4 hypothetical protein compare
Psest_3938 +0.6 1.6 Uncharacterized protein conserved in bacteria compare
Psest_4335 +0.5 1.4 Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems compare
Psest_2101 +0.5 1.1 hypothetical protein compare
Psest_3664 +0.5 0.9 Predicted phosphotransferase related to Ser/Thr protein kinases compare
Psest_1986 +0.5 0.9 3-phosphoshikimate 1-carboxyvinyltransferase compare
Psest_1718 +0.5 2.7 flagellar hook-basal body complex protein FliE compare
Psest_3304 +0.5 2.8 ABC-type transport system involved in resistance to organic solvents, auxiliary component compare
Psest_2961 +0.5 3.2 Flagellar basal-body P-ring protein compare
Psest_3389 +0.5 1.5 hypothetical protein compare
Psest_3784 +0.5 1.3 glyceraldehyde-3-phosphate dehydrogenase, type I compare
Psest_4323 +0.5 4.3 Predicted acyltransferases compare
Psest_4258 +0.5 1.6 ABC-type uncharacterized transport system, auxiliary component compare
Psest_3013 +0.5 1.0 cobyrinic acid a,c-diamide synthase compare
Psest_1655 +0.5 3.1 NADH:ubiquinone oxidoreductase, Na(+)-translocating, A subunit compare
Psest_4406 +0.5 1.1 hypothetical protein compare
Psest_3395 +0.5 0.6 hypothetical protein compare
Psest_3113 +0.5 1.6 electron transport complex, RnfABCDGE type, B subunit compare
Psest_0457 +0.5 1.9 Lipopolysaccharide kinase (Kdo/WaaP) family. compare
Psest_1377 +0.5 2.0 hypothetical protein compare
Psest_0078 +0.5 0.9 hypothetical protein compare
Psest_0601 +0.5 2.3 hypothetical protein compare
Psest_2944 +0.5 1.5 lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase compare
Psest_0309 +0.5 1.1 RND family efflux transporter, MFP subunit compare
Psest_0082 +0.5 1.2 Domain of unknown function (DUF892). compare
Psest_3914 +0.5 2.6 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) compare
Psest_2067 +0.5 1.5 ABC-type oligopeptide transport system, periplasmic component compare
Psest_0376 +0.5 1.8 glucarate dehydratase compare
Psest_2229 +0.5 2.0 Uncharacterized protein conserved in bacteria compare
Psest_2083 +0.5 3.2 Putative sterol carrier protein compare
Psest_0367 +0.5 0.8 Predicted branched-chain amino acid permease (azaleucine resistance) compare
Psest_3812 +0.5 1.5 Uncharacterized protein conserved in bacteria compare
Psest_0379 +0.5 1.9 Galactose mutarotase and related enzymes compare
Psest_4382 +0.5 4.4 hypothetical protein compare
Psest_2135 +0.5 1.9 Peroxiredoxin compare
Psest_3910 +0.5 0.8 Uncharacterized protein conserved in bacteria compare
Psest_3502 +0.5 1.3 flavoprotein, HI0933 family/uncharacterized flavoprotein, PP_4765 family compare
Psest_2671 +0.5 1.4 Transcriptional regulator compare
Psest_2458 +0.5 1.7 MoxR-like ATPases compare
Psest_0993 +0.5 3.3 Glucose-6-phosphate isomerase compare
Psest_3841 +0.5 3.2 D-lactate/glycolate dehydrogenase, FAD-linked subunit GlcD (EC 1.1.99.6; EC 1.1.99.14) (from data) compare
Psest_1951 +0.5 1.2 Uncharacterized protein conserved in bacteria compare
Psest_1087 +0.5 1.1 uncharacterized peroxidase-related enzyme compare
Psest_3482 +0.5 1.6 Parvulin-like peptidyl-prolyl isomerase compare
Psest_1837 +0.5 3.4 Endoglucanase compare
Psest_0161 +0.5 1.3 Membrane-bound metallopeptidase compare
Psest_3990 +0.5 3.1 PAP2 superfamily. compare
Psest_3907 +0.5 2.6 Uncharacterized conserved protein compare
Psest_1912 +0.5 1.8 Protein of unknown function (DUF1260). compare
Psest_2134 +0.5 3.8 amino acid carrier protein compare
Psest_4371 +0.5 1.4 Multisubunit Na+/H+ antiporter, MnhB subunit compare
Psest_3005 +0.5 0.8 Fructose-2,6-bisphosphatase compare
Psest_0181 +0.5 3.0 glycine cleavage system T protein compare
Psest_2899 +0.5 0.8 hypothetical protein compare
Psest_0224 +0.5 2.6 Transcriptional regulator compare
Psest_1805 +0.5 1.1 integration host factor, beta subunit compare
Psest_1632 +0.4 1.4 Predicted permeases compare
Psest_2282 +0.4 1.7 Dihydroorotate dehydrogenase compare
Psest_2963 +0.4 2.9 flagellar basal-body rod protein FlgG, Gram-negative bacteria compare
Psest_0402 +0.4 0.8 glycosyltransferase, MGT family compare
Psest_1574 +0.4 1.4 phenazine biosynthesis protein PhzF family compare
Psest_0227 +0.4 1.0 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific compare
Psest_3307 +0.4 2.9 ABC-type transport system involved in resistance to organic solvents, ATPase component compare
Psest_3467 +0.4 2.2 PAP2 (acid phosphatase) superfamily protein compare
Psest_3803 +0.4 0.8 DNA repair protein radc compare
Psest_0064 +0.4 0.7 Transcriptional regulator compare
Psest_1613 +0.4 2.2 hypothetical protein compare
Psest_2455 +0.4 2.2 Acyl-CoA thioesterase compare
Psest_2969 +0.4 2.8 Methylase of chemotaxis methyl-accepting proteins compare
Psest_2894 +0.4 1.7 addiction module antidote protein, HigA family compare
Psest_1864 +0.4 2.4 diguanylate cyclase (GGDEF) domain compare
Psest_4055 +0.4 2.2 ABC transporter, substrate-binding protein, aliphatic sulfonates family compare
Psest_0013 +0.4 2.7 Lauroyl/myristoyl acyltransferase compare
Psest_4403 +0.4 2.7 hypothetical protein compare
Psest_0669 +0.4 2.3 Ethanolamine ammonia-lyase, large subunit compare
Psest_3546 +0.4 0.5 Phosphatidylglycerophosphatase A and related proteins compare
Psest_2724 +0.4 1.3 hypothetical protein compare
Psest_3789 +0.4 1.6 Uncharacterized protein containing double-stranded beta helix domain compare
Psest_1187 +0.4 2.5 exodeoxyribonuclease III compare
Psest_3934 +0.4 1.6 rRNA methylase, putative, group 2 compare
Psest_3516 +0.4 2.0 Leucine dehydrogenase (EC 1.4.1.9) (from data) compare
Psest_2405 +0.4 0.8 NAD-dependent protein deacetylases, SIR2 family compare
Psest_1636 +0.4 1.5 putative transporter, required for glycine utilization (from data) compare
Psest_2041 +0.4 1.8 ABC transporter, ATP-binding subunit, PQQ-dependent alcohol dehydrogenase system compare
Psest_2965 +0.4 3.6 fagellar hook-basal body proteins compare
Psest_0364 +0.4 2.3 Gluconolactonase compare
Psest_0240 +0.4 2.0 hypothetical protein compare
Psest_0215 +0.4 1.7 hypothetical protein compare
Psest_4009 +0.4 2.0 conserverd hypothetical protein compare
Psest_1625 +0.4 0.8 hypothetical protein compare
Psest_0305 +0.4 2.1 RNA methyltransferase, RsmE family compare
Psest_3361 +0.4 1.5 Uncharacterized protein conserved in bacteria compare
Psest_2277 +0.4 1.4 coenzyme PQQ biosynthesis protein A compare
Psest_1974 +0.4 1.1 integration host factor, alpha subunit compare
Psest_1765 +0.4 2.1 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_2586 +0.4 3.5 FimV N-terminal domain compare
Psest_1639 +0.4 1.6 23S rRNA (uracil-5-)-methyltransferase RumA compare
Psest_3699 +0.4 1.6 Dehydrogenases (flavoproteins) compare
Psest_1870 +0.4 0.6 Transcriptional regulators compare
Psest_0765 +0.4 1.4 hypothetical protein compare
Psest_0856 +0.4 1.6 Predicted oxidoreductase compare
Psest_3303 +0.4 2.0 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) compare
Psest_3757 +0.4 1.1 TIGR02647 family protein compare
Psest_1204 +0.4 0.9 Transcriptional regulators compare
Psest_1368 +0.4 2.4 Putative threonine efflux protein compare
Psest_3447 +0.4 0.4 Uncharacterized MobA-related protein compare
Psest_0204 +0.4 1.4 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_2762 +0.4 1.0 hypothetical protein compare
Psest_2964 +0.4 2.4 flagellar basal-body rod protein FlgF compare
Psest_4209 +0.4 0.9 Uncharacterized conserved small protein compare


Specific Phenotypes

For 10 genes in this experiment

For stress Cisplatin in Pseudomonas stutzeri RCH2

For stress Cisplatin across organisms