Experiment set6H31 for Pseudomonas stutzeri RCH2

Compare to:

RCH2 defined media with sodium fluoride 25 mM

200 most important genes:

  gene name fitness t score description  
Psest_2035 -8.1 -6.6 crcB protein conserved
Psest_3647 -5.7 -7.9 Indole-3-glycerol phosphate synthase compare
Psest_2584 -5.7 -6.8 Phosphoribosylanthranilate isomerase compare
Psest_0279 -5.6 -5.5 methionine biosynthesis protein MetW compare
Psest_2579 -5.6 -5.4 amidophosphoribosyltransferase compare
Psest_3650 -5.6 -11.9 anthranilate synthase component I, non-proteobacterial lineages compare
Psest_0153 -5.5 -11.7 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit compare
Psest_2578 -5.2 -16.7 O-succinylhomoserine sulfhydrylase compare
Psest_2591 -5.2 -5.1 3-isopropylmalate dehydratase, large subunit compare
Psest_0152 -5.1 -6.0 Imidazoleglycerol-phosphate dehydratase compare
Psest_0508 -5.0 -9.6 gamma-glutamyl phosphate reductase compare
Psest_3866 -5.0 -16.6 threonine ammonia-lyase, biosynthetic, long form compare
Psest_3648 -5.0 -11.1 anthranilate phosphoribosyltransferase compare
Psest_3384 -5.0 -10.1 glutamate 5-kinase compare
Psest_3298 -4.7 -10.9 histidinol dehydrogenase compare
Psest_0155 -4.6 -7.7 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Psest_0326 -4.6 -18.0 Taurine catabolism dioxygenase TauD, TfdA family. compare
Psest_1295 -4.5 -11.2 Aspartate/tyrosine/aromatic aminotransferase compare
Psest_3299 -4.5 -15.7 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Psest_2590 -4.4 -2.5 3-isopropylmalate dehydratase, small subunit compare
Psest_0062 -4.3 -8.8 tryptophan synthase, alpha subunit compare
Psest_3864 -4.3 -16.0 Histidinol-phosphatase (EC:3.1.3.15) (from data) compare
Psest_0280 -4.3 -17.0 homoserine O-acetyltransferase compare
Psest_2589 -4.3 -16.3 3-isopropylmalate dehydrogenase compare
Psest_1474 -4.2 -4.1 phosphoribosylaminoimidazole synthetase compare
Psest_1013 -4.1 -2.9 phosphoribosylamine--glycine ligase compare
Psest_0325 -4.0 -14.9 Putative threonine efflux protein compare
Psest_0687 -4.0 -11.9 ATP phosphoribosyltransferase, regulatory subunit compare
Psest_3226 -4.0 -2.3 Predicted membrane protein compare
Psest_3649 -3.9 -12.8 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase compare
Psest_0954 -3.8 -10.6 Fe-S oxidoreductase compare
Psest_1473 -3.8 -7.2 phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent compare
Psest_0063 -3.8 -7.7 tryptophan synthase, beta subunit compare
Psest_0953 -3.8 -11.7 iron-sulfur cluster-binding protein compare
Psest_3159 -3.7 -11.6 phosphoribosylformylglycinamidine synthase, single chain form compare
Psest_1452 -3.7 -9.1 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase compare
Psest_3944 -3.6 -4.2 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Psest_0952 -3.5 -5.7 Uncharacterized conserved protein compare
Psest_2988 -3.4 -10.5 aspartate kinase, monofunctional class compare
Psest_1772 -3.3 -8.0 Aspartate/tyrosine/aromatic aminotransferase compare
Psest_0313 -3.3 -5.0 5,10-methylenetetrahydrofolate reductase, prokaryotic form compare
Psest_1037 -3.3 -5.3 acetolactate synthase, small subunit compare
Psest_1947 -3.1 -3.0 dihydroorotate dehydrogenase, subfamily 2 compare
Psest_3810 -3.1 -2.9 orotate phosphoribosyltransferase compare
Psest_1509 -3.0 -12.0 quinolinate synthetase complex, A subunit compare
Psest_2945 -2.9 -2.7 septum site-determining protein MinC compare
Psest_0489 -2.8 -3.3 phosphoserine phosphatase SerB compare
Psest_2034 -2.8 -8.9 ATPase related to the helicase subunit of the Holliday junction resolvase conserved
Psest_1686 -2.7 -7.5 fatty acid/phospholipid synthesis protein PlsX compare
Psest_3818 -2.6 -9.4 endoribonuclease L-PSP, putative compare
Psest_0718 -2.5 -6.8 nicotinate-nucleotide pyrophosphorylase compare
Psest_0411 -2.5 -10.8 biotin synthetase compare
Psest_2329 -2.3 -15.2 Transcriptional regulator compare
Psest_2104 -2.2 -3.6 IscR-regulated protein YhgI compare
Psest_3123 -2.2 -4.1 dihydroorotase, homodimeric type compare
Psest_0958 -1.9 -11.3 Oligoketide cyclase/lipid transport protein compare
Psest_2585 -1.9 -1.6 pseudouridylate synthase I compare
Psest_2527 -1.9 -9.1 cytochrome c oxidase, cbb3-type, subunit I compare
Psest_3721 -1.9 -7.1 Malic enzyme compare
Psest_2532 -1.8 -4.6 Uncharacterized protein conserved in bacteria compare
Psest_3943 -1.8 -3.8 Phosphoribosyl-AMP cyclohydrolase compare
Psest_3297 -1.8 -8.4 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Psest_0267 -1.8 -10.8 Uncharacterized enzyme of thiazole biosynthesis compare
Psest_3862 -1.7 -11.8 phosphoenolpyruvate-protein phosphotransferase compare
Psest_0266 -1.7 -7.1 thiamine biosynthesis protein ThiS compare
Psest_1115 -1.7 -4.0 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 compare
Psest_1704 -1.7 -3.5 Dehydrogenases (flavoproteins) compare
Psest_2531 -1.7 -12.2 cytochrome c oxidase accessory protein FixG compare
Psest_2088 -1.6 -3.2 Uncharacterized protein conserved in bacteria compare
Psest_3317 -1.6 -5.7 Phosphotransferase System HPr (HPr) Family compare
Psest_0212 -1.6 -1.4 exodeoxyribonuclease V, gamma subunit compare
Psest_0536 -1.5 -3.1 thiamine-phosphate pyrophosphorylase compare
Psest_0537 -1.5 -1.7 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase compare
Psest_4084 -1.5 -10.6 oxaloacetate decarboxylase alpha subunit compare
Psest_0207 -1.5 -3.0 hypothetical protein compare
Psest_0477 -1.5 -9.5 thiamine biosynthesis protein ThiC compare
Psest_2923 -1.5 -2.3 hypothetical protein compare
Psest_0175 -1.4 -5.9 Xaa-Pro aminopeptidase compare
Psest_3732 -1.4 -7.0 polyphosphate kinase 1 compare
Psest_3092 -1.4 -2.4 ribonuclease III, bacterial compare
Psest_4406 -1.4 -1.9 hypothetical protein compare
Psest_0955 -1.4 -4.6 D,L-lactate:H+ symporter (from data) compare
Psest_4085 -1.4 -9.4 Biotin carboxylase compare
Psest_2530 -1.4 -6.8 cytochrome c oxidase, cbb3-type, subunit III compare
Psest_3338 -1.4 -2.1 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain compare
Psest_0511 -1.4 -1.8 rRNA large subunit m3Psi methyltransferase RlmH compare
Psest_4051 -1.4 -2.9 molybdenum-pterin binding domain compare
Psest_3790 -1.4 -7.3 Cytochrome c5 compare
Psest_2864 -1.3 -4.1 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain compare
Psest_4256 -1.3 -2.1 ABC-type transport system involved in resistance to organic solvents, ATPase component compare
Psest_1640 -1.3 -9.9 (p)ppGpp synthetase, RelA/SpoT family compare
Psest_1012 -1.3 -4.0 Signal transduction histidine kinase compare
Psest_0060 -1.3 -1.7 Predicted Fe-S protein compare
Psest_1527 -1.3 -8.9 Na+/proline symporter compare
Psest_0951 -1.3 -7.6 FAD/FMN-containing dehydrogenases compare
Psest_0191 -1.3 -1.1 PAS domain S-box compare
Psest_0209 -1.3 -0.9 membrane protein AbrB duplication compare
Psest_3908 -1.2 -1.2 Cytochrome c553 compare
Psest_4086 -1.2 -7.3 Transcriptional regulator compare
Psest_0415 -1.2 -3.3 dethiobiotin synthase compare
Psest_0867 -1.2 -1.7 hypothetical protein compare
Psest_0644 -1.2 -2.3 siderophore ferric iron reductase, AHA_1954 family compare
Psest_4191 -1.2 -2.4 Transcriptional regulator compare
Psest_0097 -1.2 -1.2 phosphonates metabolism transcriptional regulator PhnF compare
Psest_0413 -1.2 -5.2 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) compare
Psest_3828 -1.2 -0.8 zinc-binding alcohol dehydrogenase family protein compare
Psest_1679 -1.2 -2.3 ribonuclease, Rne/Rng family compare
Psest_1511 -1.1 -3.6 Predicted redox protein, regulator of disulfide bond formation compare
Psest_0412 -1.1 -7.0 8-amino-7-oxononanoate synthase compare
Psest_1656 -1.1 -2.5 NADH:ubiquinone oxidoreductase, Na(+)-translocating, B subunit compare
Psest_0520 -1.1 -1.1 hypothetical protein compare
Psest_0442 -1.1 -4.3 ATPases of the AAA+ class compare
Psest_0414 -1.1 -3.5 biotin biosynthesis protein BioC compare
Psest_3700 -1.1 -0.4 hypothetical protein compare
Psest_3896 -1.1 -1.4 arsenite-activated ATPase ArsA compare
Psest_4049 -1.1 -2.1 hypothetical protein compare
Psest_0722 -1.0 -5.5 Predicted ATPase compare
Psest_0154 -1.0 -4.0 Uncharacterized conserved protein compare
Psest_1388 -1.0 -1.2 Uncharacterized protein conserved in bacteria compare
Psest_3766 -1.0 -2.1 Uncharacterized protein conserved in bacteria compare
Psest_0359 -1.0 -1.7 Transcriptional regulators compare
Psest_3554 -1.0 -1.3 Uncharacterized protein conserved in bacteria compare
Psest_3031 -1.0 -1.1 hypothetical protein compare
Psest_0192 -0.9 -4.5 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_0292 -0.9 -1.5 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase compare
Psest_1076 -0.9 -2.3 acetyl-CoA acetyltransferases compare
Psest_0820 -0.9 -2.5 hypothetical protein compare
Psest_1242 -0.9 -3.0 tRNA-guanine transglycosylase, queuosine-34-forming compare
Psest_0306 -0.9 -6.8 adenosylmethionine-8-amino-7-oxononanoate transaminase compare
Psest_4303 -0.9 -0.8 HEAT repeat. compare
Psest_3014 -0.9 -1.5 cob(I)alamin adenosyltransferase compare
Psest_2357 -0.9 -1.5 Short-chain dehydrogenases of various substrate specificities compare
Psest_0828 -0.9 -3.4 Nitric oxide reductase activation protein compare
Psest_1661 -0.9 -1.8 Membrane-associated lipoprotein involved in thiamine biosynthesis compare
Psest_4044 -0.8 -3.7 type I site-specific deoxyribonuclease, HsdR family compare
Psest_1176 -0.8 -2.1 Urea transporter compare
Psest_0086 -0.8 -2.0 hypothetical protein compare
Psest_3458 -0.8 -1.2 hypothetical protein compare
Psest_0064 -0.8 -0.7 Transcriptional regulator compare
Psest_0174 -0.8 -3.8 Uncharacterized protein conserved in bacteria compare
Psest_3448 -0.8 -2.7 Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family compare
Psest_1238 -0.8 -5.0 Predicted membrane protein/domain compare
Psest_0309 -0.8 -0.7 RND family efflux transporter, MFP subunit compare
Psest_3767 -0.8 -2.4 tyrosine recombinase XerC compare
Psest_0327 -0.8 -3.5 Transcriptional regulator compare
Psest_3479 -0.8 -1.8 molybdenum cofactor synthesis domain compare
Psest_0294 -0.8 -2.3 Putative transcriptional regulator compare
Psest_2119 -0.8 -1.8 Glycine/D-amino acid oxidases (deaminating) compare
Psest_2566 -0.8 -0.8 Uncharacterized protein conserved in bacteria compare
Psest_0334 -0.8 -2.4 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_1496 -0.8 -1.4 Holliday junction DNA helicase, RuvA subunit compare
Psest_3518 -0.8 -1.1 Transcriptional regulators compare
Psest_1612 -0.8 -2.2 ABC-type multidrug transport system, ATPase component compare
Psest_1221 -0.8 -4.1 Uncharacterized conserved protein compare
Psest_2946 -0.8 -2.6 septum site-determining protein MinD compare
Psest_3178 -0.8 -2.3 formyltetrahydrofolate deformylase compare
Psest_3795 -0.8 -4.2 Glycine/D-amino acid oxidases (deaminating) compare
Psest_1284 -0.8 -3.2 exodeoxyribonuclease VII, large subunit compare
Psest_1144 -0.8 -1.6 AmpG-related permease compare
Psest_2955 -0.7 -1.7 Predicted transcriptional regulator with C-terminal CBS domains compare
Psest_0734 -0.7 -1.2 RND family efflux transporter, MFP subunit compare
Psest_1022 -0.7 -4.2 Thiol:disulfide interchange protein compare
Psest_2645 -0.7 -3.8 Transcriptional regulator compare
Psest_0078 -0.7 -0.5 hypothetical protein compare
Psest_0661 -0.7 -3.3 PAS domain S-box compare
Psest_1367 -0.7 -3.3 hypothetical protein compare
Psest_4301 -0.7 -1.8 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_0216 -0.7 -2.4 Predicted permeases compare
Psest_3998 -0.7 -3.0 glutamate--cysteine ligase compare
Psest_2758 -0.7 -1.7 Predicted transcriptional regulators compare
Psest_3932 -0.7 -2.8 nitrogen regulation protein NR(I) compare
Psest_3962 -0.7 -1.3 haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED compare
Psest_2460 -0.7 -0.8 hypothetical protein compare
Psest_1139 -0.7 -2.2 PAS domain S-box compare
Psest_0785 -0.7 -1.7 Thioredoxin reductase compare
Psest_2630 -0.7 -1.7 hypothetical protein compare
Psest_3963 -0.7 -4.7 PAS domain S-box compare
Psest_4341 -0.7 -2.7 hypothetical protein compare
Psest_0227 -0.6 -1.1 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific compare
Psest_4098 -0.6 -1.6 Superfamily I DNA and RNA helicases compare
Psest_4221 -0.6 -1.8 homoserine kinase, Neisseria type compare
Psest_2348 -0.6 -2.1 urea carboxylase-associated protein 2 compare
Psest_2177 -0.6 -1.9 Protein of unknown function (DUF1652). compare
Psest_0450 -0.6 -3.4 Branched-chain amino acid aminotransferase (EC 2.6.1.42) (from data) compare
Psest_1563 -0.6 -1.6 Protein of unknown function (DUF548). compare
Psest_0316 -0.6 -1.5 Cytochrome c556 compare
Psest_0471 -0.6 -3.0 hypothetical protein compare
Psest_2744 -0.6 -0.9 Uncharacterized conserved protein compare
Psest_2872 -0.6 -1.3 protein RecA compare
Psest_2525 -0.6 -2.2 cytochrome c oxidase, cbb3-type, subunit II compare
Psest_2067 -0.6 -1.4 ABC-type oligopeptide transport system, periplasmic component compare
Psest_1498 -0.6 -1.6 tol-pal system-associated acyl-CoA thioesterase compare
Psest_4005 -0.6 -2.7 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB compare
Psest_3735 -0.6 -1.7 uncharacterized domain 1 compare
Psest_0218 -0.6 -1.8 Acyl-CoA hydrolase compare
Psest_0476 -0.6 -3.4 type I secretion outer membrane protein, TolC family compare
Psest_2667 -0.6 -1.6 Uncharacterized protein involved in propionate catabolism compare
Psest_3543 -0.6 -2.0 hypothetical protein compare
Psest_3112 -0.6 -3.3 electron transport complex, RnfABCDGE type, A subunit compare
Psest_1565 -0.6 -2.3 RND family efflux transporter, MFP subunit compare


Specific Phenotypes

For 2 genes in this experiment

For stress sodium fluoride in Pseudomonas stutzeri RCH2

For stress sodium fluoride across organisms