Experiment set6H31 for Pseudomonas stutzeri RCH2

Compare to:

RCH2 defined media with sodium fluoride 25 mM

200 most detrimental genes:

  gene name fitness t score description  
Psest_0401 +3.2 3.4 isopentenyl-diphosphate delta-isomerase, type 2 compare
Psest_1840 +2.8 26.3 Undecaprenyl-phosphate glucose phosphotransferase compare
Psest_2066 +1.8 1.7 ABC-type uncharacterized transport system, permease component compare
Psest_2232 +1.8 14.6 UTP-glucose-1-phosphate uridylyltransferase compare
Psest_1635 +1.7 15.8 Signal transduction histidine kinase compare
Psest_2260 +1.6 14.9 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain compare
Psest_1805 +1.5 4.1 integration host factor, beta subunit compare
Psest_3697 +1.4 2.1 Outer membrane lipoprotein carrier protein LolA. compare
Psest_0164 +1.4 1.6 Glutaredoxin, GrxC family compare
Psest_0089 +1.3 3.1 phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN compare
Psest_3904 +1.3 1.4 hypothetical protein compare
Psest_1457 +1.2 2.4 FOG: Ankyrin repeat compare
Psest_3447 +1.2 1.0 Uncharacterized MobA-related protein compare
Psest_2136 +1.1 7.2 Predicted homoserine dehydrogenase compare
Psest_0717 +1.1 9.5 Protein of unknown function (DUF1631). compare
Psest_3937 +1.1 1.6 ATP-dependent protease HslVU, ATPase subunit compare
Psest_1819 +1.1 10.1 Nucleoside-diphosphate-sugar epimerases compare
Psest_2775 +1.0 4.6 Glycerol-3-phosphate dehydrogenase compare
Psest_1424 +1.0 2.3 Lipoate-protein ligase A compare
Psest_0999 +1.0 3.2 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_4142 +1.0 1.7 hypothetical protein compare
Psest_1602 +1.0 1.3 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_0993 +1.0 6.9 Glucose-6-phosphate isomerase compare
Psest_0367 +1.0 1.9 Predicted branched-chain amino acid permease (azaleucine resistance) compare
Psest_1817 +1.0 4.4 hypothetical protein compare
Psest_2243 +0.9 1.7 glyceraldehyde-3-phosphate dehydrogenase, type I compare
Psest_1923 +0.9 4.4 adhesin-associated BNR repeat protein (from data) compare
Psest_1813 +0.9 7.1 pseudaminic acid biosynthesis-associated protein PseG compare
Psest_4008 +0.8 6.7 PAS domain S-box compare
Psest_1814 +0.8 7.7 pseudaminic acid biosynthesis N-acetyl transferase compare
Psest_3008 +0.8 2.4 cobyric acid synthase CobQ compare
Psest_2762 +0.8 2.3 hypothetical protein compare
Psest_4325 +0.8 2.8 hypothetical protein compare
Psest_0538 +0.8 7.8 Signal transduction histidine kinase compare
Psest_1888 +0.8 1.2 Sua5/YciO/YrdC/YwlC family protein compare
Psest_1206 +0.8 2.5 ABC-type Mn2+/Zn2+ transport systems, permease components compare
Psest_0031 +0.8 1.3 Uncharacterized conserved protein compare
Psest_0368 +0.8 0.6 Transcriptional regulator compare
Psest_3129 +0.8 1.4 tyrosine recombinase XerD compare
Psest_3664 +0.8 1.4 Predicted phosphotransferase related to Ser/Thr protein kinases compare
Psest_1122 +0.8 6.6 putative adhesin (DUF1302) (from data) compare
Psest_3816 +0.7 1.4 DNA-directed RNA polymerase, omega subunit compare
Psest_4315 +0.7 1.5 ABC-type metal ion transport system, permease component compare
Psest_3174 +0.7 6.5 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase compare
Psest_2370 +0.7 2.7 Protein of unknown function (DUF1652). compare
Psest_3550 +0.7 1.5 3,4-dihydroxy-2-butanone 4-phosphate synthase compare
Psest_3699 +0.7 2.7 Dehydrogenases (flavoproteins) compare
Psest_1974 +0.7 2.8 integration host factor, alpha subunit compare
Psest_0487 +0.7 2.9 Uncharacterized protein conserved in bacteria compare
Psest_1071 +0.7 2.8 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains compare
Psest_0095 +0.7 2.0 phosphonate C-P lyase system protein PhnH compare
Psest_2072 +0.7 5.0 Methyltransferase domain. compare
Psest_0091 +0.7 2.2 phosphonate C-P lyase system protein PhnL compare
Psest_2551 +0.7 4.5 1-aminocyclopropane-1-carboxylate deaminase compare
Psest_1625 +0.7 2.6 hypothetical protein compare
Psest_3216 +0.7 6.5 diguanylate cyclase (GGDEF) domain compare
Psest_0355 +0.7 1.7 Glycine cleavage system regulatory protein compare
Psest_4258 +0.7 1.8 ABC-type uncharacterized transport system, auxiliary component compare
Psest_2333 +0.7 1.4 Protein of unknown function (DUF3359). compare
Psest_2538 +0.7 1.8 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases compare
Psest_3306 +0.7 2.9 conserved hypothetical integral membrane protein compare
Psest_3449 +0.7 0.9 DJ-1 family protein compare
Psest_1804 +0.6 2.1 Superfamily II DNA and RNA helicases compare
Psest_4273 +0.6 4.5 Lysophospholipase compare
Psest_1065 +0.6 1.5 hypothetical protein compare
Psest_3988 +0.6 3.6 phosphoenolpyruvate carboxykinase (ATP) compare
Psest_0662 +0.6 1.2 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain compare
Psest_2950 +0.6 3.0 putative NAD(P)H quinone oxidoreductase, PIG3 family compare
Psest_2268 +0.6 2.7 Alcohol dehydrogenase, class IV compare
Psest_3707 +0.6 2.2 Transcriptional regulator compare
Psest_3480 +0.6 1.1 molybdenum cofactor biosynthesis protein B, proteobacterial compare
Psest_3476 +0.6 0.8 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_2101 +0.6 1.5 hypothetical protein compare
Psest_3304 +0.6 2.8 ABC-type transport system involved in resistance to organic solvents, auxiliary component compare
Psest_3954 +0.6 2.1 Small protein A (tmRNA-binding) compare
Psest_3698 +0.6 2.0 Predicted exporter compare
Psest_2446 +0.6 1.5 acetyl-CoA acetyltransferases compare
Psest_0737 +0.6 0.7 Cu(I)-responsive transcriptional regulator compare
Psest_0066 +0.6 0.9 Protein of unknown function (DUF3060). compare
Psest_0446 +0.6 4.3 hypothetical protein compare
Psest_1167 +0.6 1.0 hypothetical protein compare
Psest_3884 +0.6 0.5 Signal transduction histidine kinase compare
Psest_3395 +0.6 1.2 hypothetical protein compare
Psest_3080 +0.6 1.6 AraC-type DNA-binding domain-containing proteins compare
Psest_2647 +0.6 2.3 SOS-response cell division inhibitor, blocks FtsZ ring formation compare
Psest_2565 +0.6 1.6 Transcriptional regulator compare
Psest_3307 +0.6 3.3 ABC-type transport system involved in resistance to organic solvents, ATPase component compare
Psest_1837 +0.6 3.3 Endoglucanase compare
Psest_0457 +0.6 2.0 Lipopolysaccharide kinase (Kdo/WaaP) family. compare
Psest_3895 +0.6 1.3 hypothetical protein compare
Psest_3217 +0.6 5.4 PAS domain S-box compare
Psest_3803 +0.6 0.8 DNA repair protein radc compare
Psest_3907 +0.5 2.5 Uncharacterized conserved protein compare
Psest_3731 +0.5 4.4 exopolyphosphatase compare
Psest_2637 +0.5 1.2 putative methyltransferase, YaeB/AF_0241 family compare
Psest_1997 +0.5 1.9 6-phosphogluconolactonase compare
Psest_0853 +0.5 1.4 6-phosphogluconolactonase compare
Psest_4219 +0.5 1.3 DNA polymerase I compare
Psest_3044 +0.5 3.0 deoxycytidine triphosphate deaminase compare
Psest_3343 +0.5 1.5 Predicted periplasmic protein compare
Psest_4323 +0.5 4.2 Predicted acyltransferases compare
Psest_1774 +0.5 0.8 Glutathione peroxidase compare
Psest_1824 +0.5 1.7 Sugar transferases involved in lipopolysaccharide synthesis compare
Psest_3177 +0.5 0.9 hypothetical protein compare
Psest_1001 +0.5 1.3 hypothetical protein compare
Psest_1016 +0.5 1.9 putative TIM-barrel protein, nifR3 family compare
Psest_0498 +0.5 0.8 ribosome small subunit-dependent GTPase A compare
Psest_3389 +0.5 1.3 hypothetical protein compare
Psest_2447 +0.5 0.9 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) compare
Psest_3370 +0.5 3.3 prepilin-type N-terminal cleavage/methylation domain compare
Psest_0020 +0.5 2.1 K+ transport systems, NAD-binding component compare
Psest_3467 +0.5 2.5 PAP2 (acid phosphatase) superfamily protein compare
Psest_0716 +0.5 1.4 Protein of unknown function (DUF3094). compare
Psest_4054 +0.5 1.5 alkanesulfonate monooxygenase, FMNH(2)-dependent compare
Psest_0225 +0.5 0.8 Predicted permease, DMT superfamily compare
Psest_3064 +0.5 1.2 hypothetical protein compare
Psest_2887 +0.5 1.4 Uncharacterized protein conserved in bacteria compare
Psest_1408 +0.5 2.1 Predicted unusual protein kinase compare
Psest_2429 +0.5 1.8 Predicted branched-chain amino acid permease (azaleucine resistance) compare
Psest_0119 +0.5 1.2 hypothetical protein compare
Psest_4265 +0.5 3.0 dTDP-4-dehydrorhamnose reductase compare
Psest_0851 +0.5 3.5 Transcriptional regulators compare
Psest_0814 +0.5 1.3 MoxR-like ATPases compare
Psest_1924 +0.5 4.0 adhesin-associated MmpL efflux pump (from data) compare
Psest_1162 +0.5 1.5 Spermidine synthase compare
Psest_0122 +0.5 2.4 hypothetical protein compare
Psest_3711 +0.5 3.8 Glutamate synthase domain 2 compare
Psest_1809 +0.5 3.7 Membrane protein involved in the export of O-antigen and teichoic acid compare
Psest_2248 +0.5 1.4 Predicted transcriptional regulators compare
Psest_1741 +0.5 1.8 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_0959 +0.5 2.0 Uncharacterized protein conserved in bacteria compare
Psest_0298 +0.5 2.2 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_4370 +0.5 1.2 Multisubunit Na+/H+ antiporter, MnhC subunit compare
Psest_0886 +0.5 2.2 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain compare
Psest_1428 +0.5 1.4 Threonine dehydrogenase and related Zn-dependent dehydrogenases compare
Psest_3201 +0.5 2.5 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases compare
Psest_0087 +0.5 1.2 hypothetical protein compare
Psest_0141 +0.5 2.4 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain compare
Psest_2907 +0.5 0.7 Protein of unknown function (DUF3618). compare
Psest_2017 +0.5 1.9 Predicted acyltransferase compare
Psest_3749 +0.4 3.0 Response regulator of the LytR/AlgR family compare
Psest_4113 +0.4 2.8 hypothetical protein compare
Psest_2634 +0.4 2.1 glycine betaine aldehyde dehydrogenase compare
Psest_4003 +0.4 2.5 TIGR00153 family protein compare
Psest_1215 +0.4 1.0 Short-chain dehydrogenase involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) compare
Psest_2405 +0.4 1.1 NAD-dependent protein deacetylases, SIR2 family compare
Psest_4145 +0.4 1.1 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) compare
Psest_0044 +0.4 2.5 Nuclease-related domain. compare
Psest_0093 +0.4 1.0 Uncharacterized enzyme of phosphonate metabolism compare
Psest_2768 +0.4 1.5 Kef-type K+ transport systems, predicted NAD-binding component compare
Psest_3150 +0.4 2.7 hypothetical protein compare
Psest_4147 +0.4 1.7 Flagellar basal body L-ring protein compare
Psest_3100 +0.4 3.4 RNA polymerase sigma factor RpoE compare
Psest_0584 +0.4 2.3 hypothetical protein compare
Psest_0226 +0.4 1.4 Domain of unknown function (DUF3482)./GTPase of unknown function. compare
Psest_0045 +0.4 2.2 hypothetical protein compare
Psest_1434 +0.4 1.8 NADPH:quinone reductase and related Zn-dependent oxidoreductases compare
Psest_3893 +0.4 1.3 Multisubunit Na+/H+ antiporter, MnhE subunit compare
Psest_1049 +0.4 2.4 Uncharacterized paraquat-inducible protein A compare
Psest_0405 +0.4 2.1 Phytoene/squalene synthetase compare
Psest_0858 +0.4 2.1 Maltose operon periplasmic protein precursor (MalM). compare
Psest_3841 +0.4 2.7 D-lactate/glycolate dehydrogenase, FAD-linked subunit GlcD (EC 1.1.99.6; EC 1.1.99.14) (from data) compare
Psest_0041 +0.4 1.6 Uncharacterized protein conserved in bacteria compare
Psest_1395 +0.4 1.3 Short-chain alcohol dehydrogenase of unknown specificity compare
Psest_0193 +0.4 0.8 conserved hypothetical protein compare
Psest_3482 +0.4 1.4 Parvulin-like peptidyl-prolyl isomerase compare
Psest_0504 +0.4 1.6 Putative effector of murein hydrolase LrgA compare
Psest_2360 +0.4 1.0 Uncharacterized protein, putative amidase compare
Psest_4009 +0.4 1.8 conserverd hypothetical protein compare
Psest_0637 +0.4 1.9 Short-chain dehydrogenases of various substrate specificities compare
Psest_3883 +0.4 1.9 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_1980 +0.4 1.4 Uncharacterized conserved protein compare
Psest_1532 +0.4 1.3 DNA recombination-dependent growth factor C compare
Psest_0725 +0.4 1.4 Negative regulator of beta-lactamase expression compare
Psest_4330 +0.4 1.5 Protein of unknown function (DUF2909). compare
Psest_3371 +0.4 2.5 type IV pilus modification protein PilV compare
Psest_0094 +0.4 0.8 Uncharacterized enzyme of phosphonate metabolism compare
Psest_0501 +0.4 1.5 Predicted nucleoside-diphosphate-sugar epimerases compare
Psest_0402 +0.4 0.6 glycosyltransferase, MGT family compare
Psest_2773 +0.4 2.6 glycerol kinase compare
Psest_3955 +0.4 1.1 Uncharacterized protein conserved in bacteria compare
Psest_1070 +0.4 0.8 Predicted membrane protein compare
Psest_2134 +0.4 3.4 amino acid carrier protein compare
Psest_1810 +0.4 3.5 UDP-N-acetylglucosamine 4,6-dehydratase compare
Psest_1073 +0.4 1.2 TRAP-type mannitol/chloroaromatic compound transport system, small permease component compare
Psest_3794 +0.4 2.9 Transcriptional regulators compare
Psest_1305 +0.4 1.3 Heat shock protein compare
Psest_0276 +0.4 1.6 putative oxygen-independent coproporphyrinogen III oxidase compare
Psest_1752 +0.4 1.0 Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB compare
Psest_2358 +0.4 0.7 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) compare
Psest_3757 +0.4 1.5 TIGR02647 family protein compare
Psest_2668 +0.4 1.3 Lactoylglutathione lyase and related lyases compare
Psest_2919 +0.4 1.6 hypothetical protein compare
Psest_1904 +0.4 1.2 Arabinose efflux permease compare
Psest_0083 +0.4 1.2 Uncharacterized conserved protein compare
Psest_3832 +0.4 0.6 hypothetical protein compare
Psest_0194 +0.4 2.8 hypothetical protein compare
Psest_0204 +0.4 1.5 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_1812 +0.4 2.8 pseudaminic acid CMP-transferase compare
Psest_2798 +0.4 1.1 Truncated hemoglobins compare


Specific Phenotypes

For 2 genes in this experiment

For stress sodium fluoride in Pseudomonas stutzeri RCH2

For stress sodium fluoride across organisms