| | gene | name | fitness | t score | description | |
|---|
| Rv3570c | | -2.6 | -6.2 | Possible oxidoreductase. Possible 3-hydroxy-9,10-seconandrost-1,3,5(10)-triene-9,17-dione hydroxylase. | compare |
| Rv3249c | | -2.4 | -1.7 | Possible transcriptional regulatory protein (probably TetR-family) | compare |
| Rv3556c | | -2.3 | -3.3 | Probable acetyl-CoA acetyltransferase FadA6 (acetoacetyl-CoA thiolase) | compare |
| Rv3499c | | -2.2 | -9.1 | Mce-family protein Mce4A | compare |
| Rv2850c | | -2.2 | -0.8 | Possible magnesium chelatase | compare |
| Rv3495c | | -2.2 | -8.7 | Possible Mce-family lipoprotein LprN (Mce-family lipoprotein Mce4E) | compare |
| Rv0949 | | -2.1 | -1.0 | Probable ATP-dependent DNA helicase II UvrD1 | compare |
| Rv3496c | | -2.0 | -12.4 | Mce-family protein Mce4D | compare |
| Rv3571 | | -2.0 | -4.1 | Reductase component of 3-ketosteroid-9-alpha-hydroxylase KshB | compare |
| Rv3492c | | -2.0 | -2.5 | Conserved hypothetical Mce associated protein | compare |
| Rv0694 | | -1.9 | -5.1 | Possible L-lactate dehydrogenase (cytochrome) LldD1 | compare |
| Rv3537 | | -1.9 | -6.4 | Probable dehydrogenase | compare |
| Rv3494c | | -1.9 | -7.9 | Mce-family protein Mce4F | compare |
| Rv2702 | | -1.8 | -0.7 | Polyphosphate glucokinase PpgK (polyphosphate-glucose phosphotransferase) | compare |
| Rv0655 | | -1.8 | -4.5 | Possible ribonucleotide-transport ATP-binding protein ABC transporter Mkl | compare |
| Rv0761c | | -1.8 | -5.0 | Possible zinc-containing alcohol dehydrogenase NAD dependent AdhB | compare |
| Rv0696 | | -1.8 | -3.7 | Probable membrane sugar transferase | compare |
| Rv3498c | | -1.7 | -5.4 | Mce-family protein Mce4B | compare |
| Rv3500c | | -1.7 | -6.9 | Conserved integral membrane protein YrbE4B. Possible ABC transporter. | compare |
| Rv3716c | | -1.7 | -0.8 | Conserved protein | compare |
| Rv1259 | | -1.7 | -1.2 | Probable uracil DNA glycosylase, UdgB | compare |
| Rv1046c | | -1.6 | -1.0 | Hypothetical protein | compare |
| Rv3557c | | -1.6 | -4.6 | Transcriptional regulatory protein (probably TetR-family) | compare |
| Rv0695 | | -1.6 | -2.7 | Conserved hypothetical protein | compare |
| Rv0692 | | -1.6 | -4.6 | Conserved hypothetical protein | compare |
| Rv1062 | | -1.6 | -0.9 | Conserved hypothetical protein | compare |
| Rv0249c | | -1.6 | -4.2 | Probable succinate dehydrogenase [membrane anchor subunit] (succinic dehydrogenase) | compare |
| Rv3513c | | -1.5 | -1.2 | Probable fatty-acid-CoA ligase FadD18 (fragment) (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | compare |
| Rv3497c | | -1.5 | -6.6 | Mce-family protein Mce4C | compare |
| Rv0610c | | -1.5 | -0.7 | Hypothetical protein | compare |
| Rv3526 | | -1.5 | -4.9 | Oxygenase component of 3-ketosteroid-9-alpha-hydroxylase KshA | compare |
| Rv3544c | | -1.5 | -4.5 | Probable acyl-CoA dehydrogenase FadE28 | compare |
| Rv3150 | | -1.5 | -4.3 | Probable NADH dehydrogenase I (chain F) NuoF (NADH-ubiquinone oxidoreductase chain F) | compare |
| Rv3920c | | -1.5 | -1.1 | Conserved protein similar to jag protein | compare |
| Rv2799 | | -1.5 | -7.7 | Probable membrane protein | compare |
| Rv3564 | | -1.4 | -2.2 | Probable acyl-CoA dehydrogenase FadE33 | compare |
| Rv0157A | | -1.4 | -1.4 | Conserved protein | compare |
| Rv3550 | | -1.4 | -2.2 | Probable enoyl-CoA hydratase EchA20 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase) | compare |
| Rv0742 | | -1.4 | -1.5 | PE-PGRS family protein PE_PGRS8 | compare |
| Rv3569c | | -1.4 | -1.5 | 4,9-DHSA hydrolase | compare |
| Rv1131 | | -1.4 | -2.6 | Probable methylcitrate synthase PrpC | compare |
| Rv3501c | | -1.4 | -4.9 | Conserved integral membrane protein YrbE4A. Possible ABC transporter. | compare |
| Rv2206 | | -1.3 | -2.1 | Probable conserved transmembrane protein | compare |
| Rv1112 | | -1.3 | -1.4 | Probable GTP binding protein | compare |
| Rv2222c | | -1.3 | -2.5 | Probable glutamine synthetase GlnA2 (glutamine synthase) (GS-II) | compare |
| Rv2793c | | -1.3 | -1.1 | Probable tRNA pseudouridine synthase B TruB (tRNA pseudouridine 55 synthase) (PSI55 synthase) (pseudouridylate synthase) (uracil hydrolyase) | compare |
| Rv0248c | | -1.3 | -3.5 | Probable succinate dehydrogenase [iron-sulfur subunit] (succinic dehydrogenase) | compare |
| Rv2707 | | -1.3 | -8.3 | Probable conserved transmembrane alanine and leucine rich protein | compare |
| Rv3428c | | -1.2 | -0.9 | Possible transposase | compare |
| Rv0677c | | -1.2 | -1.6 | Possible conserved membrane protein MmpS5 | compare |
| Rv3338 | | -1.2 | -1.0 | Conserved hypothetical protein | compare |
| Rv3013 | | -1.2 | -1.0 | Conserved protein | compare |
| Rv3502c | | -1.2 | -3.9 | Probable short-chain type dehydrogenase/reductase. Possible 17-beta-hydroxysteroid dehydrogenase. | compare |
| Rv3493c | | -1.2 | -3.0 | Conserved hypothetical Mce associated alanine and valine rich protein | compare |
| Rv3527 | | -1.2 | -1.2 | Hypothetical protein | compare |
| Rv2635 | | -1.1 | -0.6 | Hypothetical protein | compare |
| Rv2796c | | -1.1 | -2.1 | Probable conserved lipoprotein LppV | compare |
| Rv2369c | | -1.1 | -0.9 | Hypothetical protein | compare |
| Rv3567c | | -1.1 | -2.5 | Possible oxidoreductase. Possible 3-hydroxy-9,10-seconandrost-1,3,5(10)-triene-9,17-dione hydroxylase. | compare |
| Rv3543c | | -1.1 | -2.8 | Probable acyl-CoA dehydrogenase FadE29 | compare |
| Rv3176c | | -1.1 | -2.6 | Probable epoxide hydrolase MesT (epoxide hydratase) (arene-oxide hydratase) | compare |
| Rv0247c | | -1.1 | -0.5 | Probable succinate dehydrogenase [iron-sulfur subunit] (succinic dehydrogenase) | compare |
| Rv3540c | | -1.1 | -3.0 | Probable lipid transfer protein or keto acyl-CoA thiolase Ltp2 | compare |
| Rv2862A | | -1.1 | -2.5 | Possible antitoxin VapB23 | compare |
| Rv1627c | | -1.1 | -3.6 | Probable nonspecific lipid-transfer protein | compare |
| Rv3193c | | -1.1 | -1.2 | Probable conserved transmembrane protein | compare |
| Rv0436c | | -1.1 | -1.6 | Probable CDP-diacylglycerol--serine O-phosphatidyltransferase PssA (PS synthase) (phosphatidylserine synthase) | compare |
| Rv0760c | | -1.0 | -1.4 | Conserved protein | compare |
| Rv0451c | | -1.0 | -1.2 | Probable conserved membrane protein MmpS4 | compare |
| Rv3747 | | -1.0 | -1.7 | Conserved protein | compare |
| Rv3553 | | -1.0 | -1.5 | Possible oxidoreductase | compare |
| Rv1130 | | -1.0 | -4.2 | Possible methylcitrate dehydratase PrpD | compare |
| Rv3672c | | -1.0 | -1.3 | Conserved hypothetical protein | compare |
| Rv3546 | | -1.0 | -2.2 | Probable acetyl-CoA acetyltransferase FadA5 (acetoacetyl-CoA thiolase) | compare |
| Rv0201c | | -1.0 | -1.3 | Conserved protein | compare |
| Rv3148 | | -1.0 | -2.8 | Probable NADH dehydrogenase I (chain D) NuoD (NADH-ubiquinone oxidoreductase chain D) | compare |
| Rv3198c | | -1.0 | -0.8 | Probable ATP-dependent DNA helicase II UvrD2 | compare |
| Rv3552 | | -1.0 | -2.0 | Possible CoA-transferase (beta subunit) | compare |
| Rv2462c | | -1.0 | -3.1 | Probable trigger factor (TF) protein Tig | compare |
| Rv0346c | | -0.9 | -6.1 | Possible L-asparagine permease AnsP2 (L-asparagine transport protein) | compare |
| Rv3180c | | -0.9 | -2.9 | Hypothetical alanine rich protein | compare |
| Rv2055c | | -0.9 | -1.0 | 30S ribosomal protein S18 RpsR2 | compare |
| Rv0470c | | -0.9 | -1.5 | Mycolic acid synthase PcaA (cyclopropane synthase) | compare |
| Rv3563 | | -0.9 | -0.9 | Probable acyl-CoA dehydrogenase FadE32 | compare |
| Rv1908c | | -0.9 | -1.3 | Catalase-peroxidase-peroxynitritase T KatG | compare |
| Rv1356c | | -0.9 | -3.4 | Hypothetical protein | compare |
| Rv2021c | | -0.9 | -1.7 | Transcriptional regulatory protein | compare |
| Rv1322 | | -0.9 | -1.9 | Conserved hypothetical protein | compare |
| Rv3171c | | -0.9 | -0.8 | Possible non-heme haloperoxidase Hpx | compare |
| Rv1628c | | -0.9 | -3.1 | Conserved protein | compare |
| Rv3561 | | -0.9 | -3.0 | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | compare |
| Rv3545c | | -0.9 | -3.4 | Probable cytochrome P450 125 Cyp125 | compare |
| Rv0693 | | -0.9 | -1.5 | Probable coenzyme PQQ synthesis protein E PqqE (coenzyme PQQ synthesis protein III) | compare |
| Rv1129c | | -0.9 | -1.5 | Probable transcriptional regulator protein | compare |
| Rv3033 | | -0.9 | -0.5 | Unknown protein | compare |
| Rv3549c | | -0.9 | -1.8 | Probable short-chain type dehydrogenase/reductase | compare |
| Rv3316 | | -0.9 | -1.6 | Probable succinate dehydrogenase (cytochrome B-556 subunit) SdhC (succinic dehydrogenase) (fumarate reductase) (fumarate dehydrogenase) (fumaric hydrogenase) | compare |
| Rv3723 | | -0.9 | -2.0 | Probable conserved transmembrane protein | compare |
| Rv3286c | | -0.8 | -1.4 | Alternative RNA polymerase sigma factor SigF | compare |
| Rv0033 | | -0.8 | -2.0 | Probable acyl carrier protein AcpA (ACP) | compare |
| Rv1831 | | -0.8 | -2.4 | Hypothetical protein | compare |
| Rv0955 | | -0.8 | -1.0 | Probable conserved integral membrane protein | compare |
| Rv2321c | | -0.8 | -1.0 | Probable ornithine aminotransferase (C-terminus part) RocD2 (ornithine--oxo-acid aminotransferase) | compare |
| Rv2102 | | -0.8 | -2.2 | Conserved hypothetical protein | compare |
| Rv2250c | | -0.8 | -2.6 | Possible transcriptional regulatory protein | compare |
| Rv2782c | | -0.8 | -1.8 | Probable zinc protease PepR | compare |
| Rv2281 | | -0.8 | -1.7 | Putative phosphate-transport permease PitB | compare |
| Rv3157 | | -0.8 | -4.1 | Probable NADH dehydrogenase I (chain M) NUOK (NADH-ubiquinone oxidoreductase chain M) | compare |
| Rv3346c | | -0.8 | -1.0 | Conserved transmembrane protein | compare |
| Rv1691 | | -0.8 | -1.3 | Conserved hypothetical protein | compare |
| Rv3771c | | -0.8 | -1.1 | Conserved hypothetical protein | compare |
| Rv2849c | | -0.8 | -2.7 | Probable cob(I)alamin adenosyltransferase CobO (corrinoid adenosyltransferase) (corrinoid adotransferase activity) | compare |
| Rv2049c | | -0.8 | -0.8 | Conserved hypothetical protein | compare |
| Rv2232 | | -0.8 | -1.2 | Protein tyrosine kinase transcriptional regulatory protein PtkA | compare |
| Rv3147 | | -0.8 | -1.6 | Probable NADH dehydrogenase I (chain C) NuoC (NADH-ubiquinone oxidoreductase chain C) | compare |
| Rv1798 | | -0.8 | -0.7 | ESX conserved component EccA5. ESX-5 type VII secretion system protein. | compare |
| Rv3371 | | -0.8 | -1.7 | Possible triacylglycerol synthase (diacylglycerol acyltransferase) | compare |
| Rv3149 | | -0.7 | -2.8 | Probable NADH dehydrogenase I (chain E) NuoE (NADH-ubiquinone oxidoreductase chain E) | compare |
| Rv1897c | | -0.7 | -1.3 | Conserved hypothetical protein | compare |
| Rv0038 | | -0.7 | -2.5 | Conserved protein | compare |
| Rv1422 | | -0.7 | -0.8 | Conserved hypothetical protein | compare |
| Rv1072 | | -0.7 | -0.6 | Probable conserved transmembrane protein | compare |
| Rv1507c | | -0.7 | -1.0 | Conserved protein | compare |
| Rv1010 | | -0.7 | -1.0 | Probable dimethyladenosine transferase KsgA (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase) (16S rRNA dimethylase) (high level kasugamycin resistance protein KsgA) (kasugamycin dimethyltransferase) | compare |
| Rv2383c | | -0.7 | -1.5 | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | compare |
| Rv0280 | | -0.7 | -4.7 | PPE family protein PPE3 | compare |
| Rv0392c | | -0.7 | -0.4 | Probable membrane NADH dehydrogenase NdhA | compare |
| Rv3803c | | -0.7 | -3.9 | Secreted MPT51/MPB51 antigen protein FbpD (MPT51/MPB51 antigen 85 complex C) (AG58C) (mycolyl transferase 85C) (fibronectin-binding protein C) (85C) | compare |
| Rv0494 | | -0.7 | -2.5 | Probable transcriptional regulatory protein (probably GntR-family) | compare |
| Rv2127 | | -0.7 | -3.9 | L-asparagine permease AnsP1 | compare |
| Rv0199 | | -0.7 | -1.6 | Probable conserved membrane protein | compare |
| Rv2154c | | -0.7 | -1.3 | FtsW-like protein FtsW | compare |
| Rv0458 | | -0.7 | -3.6 | Probable aldehyde dehydrogenase | compare |
| Rv0408 | | -0.7 | -2.4 | Probable phosphate acetyltransferase Pta (phosphotransacetylase) | compare |
| Rv3073c | | -0.7 | -0.9 | Conserved hypothetical protein | compare |
| Rv3261 | | -0.7 | -1.2 | Probable F420 biosynthesis protein FbiA | compare |
| Rv2014 | | -0.7 | -0.8 | Transposase | compare |
| Rv2328 | | -0.7 | -1.7 | PE family protein PE23 | compare |
| Rv3891c | | -0.7 | -1.6 | Possible ESAT-6 like protein EsxD | compare |
| Rv2444c | | -0.7 | -1.5 | Possible ribonuclease E Rne | compare |
| Rv2848c | | -0.7 | -2.2 | Probable cobyrinic acid A,C-diamide synthase CobB | compare |
| Rv0396 | | -0.7 | -1.1 | Hypothetical protein | compare |
| Rv2919c | | -0.7 | -1.0 | Probable nitrogen regulatory protein P-II GlnB | compare |
| Rv2733c | | -0.7 | -0.8 | Conserved hypothetical alanine, arginine-rich protein | compare |
| Rv2897c | | -0.7 | -1.0 | Conserved hypothetical protein | compare |
| Rv2949c | | -0.7 | -0.8 | Chorismate pyruvate lyase | compare |
| Rv3693 | | -0.7 | -1.0 | Possible conserved membrane protein | compare |
| Rv1127c | | -0.7 | -0.8 | Probable pyruvate, phosphate dikinase PpdK | compare |
| Rv2224c | | -0.6 | -4.8 | Probable carboxylesterase CaeA | compare |
| Rv3720 | | -0.6 | -2.6 | Possible fatty acid synthase | compare |
| Rv1021 | | -0.6 | -1.4 | Conserved protein | compare |
| Rv3559c | | -0.6 | -0.4 | Probable oxidoreductase | compare |
| Rv0050 | | -0.6 | -1.1 | Probable bifunctional penicillin-binding protein 1A/1B PonA1 (murein polymerase) (PBP1): penicillin-insensitive transglycosylase (peptidoglycan TGASE) + penicillin-sensitive transpeptidase (DD-transpeptidase) | compare |
| Rv2268c | | -0.6 | -1.6 | Probable cytochrome P450 128 Cyp128 | compare |
| Rv3182 | | -0.6 | -0.5 | Conserved hypothetical protein | compare |
| Rv3536c | | -0.6 | -3.0 | Probable hydratase | compare |
| Rv2588c | | -0.6 | -1.1 | Probable conserved membrane protein secretion factor YajC | compare |
| Rv3152 | | -0.6 | -3.3 | Probable NADH dehydrogenase I (chain H) NuoH (NADH-ubiquinone oxidoreductase chain H) | compare |
| Rv2331A | | -0.6 | -0.5 | Hypothetical protein | compare |
| Rv3208A | | -0.6 | -0.5 | Conserved protein TB9.4 | compare |
| Rv3140 | | -0.6 | -2.4 | Probable acyl-CoA dehydrogenase FadE23 | compare |
| Rv3759c | | -0.6 | -1.4 | Possible osmoprotectant (glycine betaine/carnitine/choline/L-proline) binding lipoprotein ProX | compare |
| Rv3897c | | -0.6 | -0.4 | Conserved hypothetical protein | compare |
| Rv3200c | | -0.6 | -1.8 | Possible transmembrane cation transporter | compare |
| Rv3156 | | -0.6 | -2.5 | Probable NADH dehydrogenase I (chain L) NuoL (NADH-ubiquinone oxidoreductase chain L) | compare |
| Rv3335c | | -0.6 | -1.1 | Probable conserved integral membrane protein | compare |
| Rv1139c | | -0.6 | -2.3 | Conserved hypothetical membrane protein | compare |
| Rv1455 | | -0.6 | -4.2 | Conserved protein | compare |
| Rv3874 | | -0.6 | -0.3 | 10 kDa culture filtrate antigen EsxB (LHP) (CFP10) | compare |
| Rv3642c | | -0.6 | -0.8 | Hypothetical protein | compare |
| Rv2437 | | -0.6 | -1.3 | Conserved transmembrane protein | compare |
| Rv1059 | | -0.6 | -0.8 | Conserved protein | compare |
| Rv1044 | | -0.6 | -1.2 | Conserved hypothetical protein | compare |
| Rv2975c | | -0.6 | -0.4 | Conserved hypothetical protein | compare |
| Rv2722 | | -0.6 | -1.4 | Conserved hypothetical protein | compare |
| Rv1106c | | -0.6 | -3.2 | 3-beta-hydroxysteroid dehydrogenase | compare |
| Rv3272 | | -0.6 | -3.3 | Conserved hypothetical protein | compare |
| Rv0765c | | -0.6 | -1.0 | Probable oxidoreductase | compare |
| Rv1176c | | -0.6 | -2.3 | Conserved hypothetical protein | compare |
| Rv2208 | | -0.6 | -1.6 | Probable cobalamin 5'-phosphate synthase CobS | compare |
| Rv2679 | | -0.6 | -1.2 | Probable enoyl-CoA hydratase EchA15 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase) | compare |
| Rv2866 | | -0.6 | -2.1 | Toxin RelG | compare |
| Rv2671 | | -0.6 | -1.7 | Possible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reductase (HTP reductase) | compare |
| Rv0019c | | -0.6 | -1.9 | Conserved protein with FHA domain, FhaB | compare |
| Rv2632c | | -0.6 | -0.5 | Conserved protein | compare |
| Rv0311 | | -0.6 | -1.0 | Unknown protein | compare |
| Rv2721c | | -0.6 | -3.4 | Possible conserved transmembrane alanine and glycine rich protein | compare |
| Rv1715 | | -0.6 | -1.9 | Probable 3-hydroxybutyryl-CoA dehydrogenase FadB3 (beta-hydroxybutyryl-CoA dehydrogenase) (BHBD) | compare |
| Rv3145 | | -0.6 | -2.1 | Probable NADH dehydrogenase I (chain A) NuoA (NADH-ubiquinone oxidoreductase chain A) | compare |
| Rv2668 | | -0.6 | -1.6 | Possible exported alanine and valine rich protein | compare |
| Rv2624c | | -0.6 | -0.4 | Universal stress protein family protein | compare |
| Rv0381c | | -0.6 | -3.1 | Hypothetical protein | compare |
| Rv2717c | | -0.6 | -2.1 | Conserved protein | compare |
| Rv2564 | | -0.6 | -2.4 | Probable glutamine-transport ATP-binding protein ABC transporter GlnQ | compare |
| Rv0905 | | -0.6 | -1.3 | Possible enoyl-CoA hydratase EchA6 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase) | compare |
| Rv1657 | | -0.6 | -1.5 | Probable arginine repressor ArgR (AHRC) | compare |
| Rv2618 | | -0.6 | -2.0 | Conserved hypothetical protein | compare |
| Rv3158 | | -0.6 | -3.0 | Probable NADH dehydrogenase I (chain N) NuoN (NADH-ubiquinone oxidoreductase chain N) | compare |
| Rv1013 | | -0.6 | -2.9 | Putative polyketide synthase Pks16 | compare |
| Rv0037c | | -0.6 | -3.6 | Probable conserved integral membrane protein | compare |