Experiment set5IT092 for Methanococcus maripaludis S2

Compare to:

Formate with Nitrofurantoin 0.25 mM

200 most important genes:

  gene name fitness t score description  
MMP_RS02235 -4.1 -13.8 CBS domain-containing protein compare
MMP_RS01020 -3.5 -1.1 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS01005 -3.4 -1.3 riboflavin synthase compare
MMP_RS03445 -3.4 -1.0 methanogenesis marker 17 protein compare
MMP_RS09020 -3.3 -1.6 hypothetical protein compare
MMP_RS01175 -3.3 -4.6 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS01755 -3.2 -1.0 DUF2097 domain-containing protein compare
MMP_RS06350 -3.2 -8.1 HesA/MoeB/ThiF family protein compare
MMP_RS08820 -3.1 -6.8 hypothetical protein compare
MMP_RS02240 -3.1 -3.5 methanogenesis marker 7 protein compare
MMP_RS01665 -2.9 -5.4 DUF2111 domain-containing protein compare
MMP_RS08000 -2.9 -12.8 methyl coenzyme M reductase-arginine methyltransferase Mmp10 compare
MMP_RS01795 -2.8 -1.6 methanogenesis marker 6 protein compare
MMP_RS06355 -2.8 -2.5 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS00300 -2.7 -0.6 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS03250 -2.6 -3.6 MJ1244 family protein compare
MMP_RS04890 -2.6 -0.7 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS04605 -2.6 -4.2 cobalt ECF transporter T component CbiQ compare
MMP_RS06680 -2.6 -12.9 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS06700 -2.5 -12.6 hypothetical protein compare
MMP_RS07845 -2.5 -2.7 LL-diaminopimelate aminotransferase compare
MMP_RS08745 -2.3 -4.9 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS06105 -2.3 -7.7 hydrogenase maturation peptidase HycI compare
MMP_RS04900 -2.3 -13.0 hypothetical protein compare
MMP_RS06170 -2.3 -10.3 ABC transporter ATP-binding protein compare
MMP_RS07635 -2.2 -5.4 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS00685 -2.2 -4.2 2-phospho-L-lactate guanylyltransferase compare
MMP_RS05415 -2.1 -4.7 DUF22 domain-containing protein compare
MMP_RS08460 -2.1 -2.2 proteasome-activating nucleotidase compare
MMP_RS07445 -2.1 -6.2 helix-turn-helix domain-containing protein compare
MMP_RS08790 -2.1 -1.8 translation initiation factor IF-2 subunit alpha compare
MMP_RS05515 -2.1 -7.9 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS00130 -2.0 -0.9 nickel-responsive transcriptional regulator NikR compare
MMP_RS01575 -2.0 -4.9 aldolase compare
MMP_RS06480 -2.0 -7.0 ABC transporter substrate-binding protein compare
MMP_RS02280 -2.0 -0.9 DUF211 domain-containing protein compare
MMP_RS05550 -2.0 -0.7 cation:proton antiporter compare
MMP_RS06120 -2.0 -2.0 UPF0147 family protein compare
MMP_RS06345 -2.0 -8.1 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS03960 -2.0 -0.7 hypothetical protein compare
MMP_RS00695 -2.0 -0.8 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS04710 -2.0 -1.4 hypothetical protein compare
MMP_RS08200 -1.9 -12.9 archaeosine synthase subunit alpha compare
MMP_RS08320 -1.9 -5.6 molybdopterin molybdotransferase MoeA compare
MMP_RS01610 -1.9 -2.6 hypothetical protein compare
MMP_RS08715 -1.9 -1.7 formylmethanofuran dehydrogenase subunit B compare
MMP_RS08195 -1.9 -8.4 hypothetical protein compare
MMP_RS06165 -1.9 -7.6 ABC transporter permease compare
MMP_RS07525 -1.9 -7.0 4Fe-4S binding protein compare
MMP_RS07005 -1.9 -0.5 4Fe-4S binding protein compare
MMP_RS00115 -1.9 -9.4 radical SAM protein compare
MMP_RS03035 -1.8 -3.8 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS06865 -1.8 -2.3 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS06295 -1.8 -5.1 methanogenesis marker 14 protein compare
MMP_RS05920 -1.8 -0.6 50S ribosomal protein L37e compare
MMP_RS06400 -1.8 -1.5 4Fe-4S binding protein compare
MMP_RS00515 -1.8 -0.8 DUF655 domain-containing protein compare
MMP_RS03015 -1.8 -6.7 GTP 3' 8-cyclase MoaA compare
MMP_RS05355 -1.7 -0.8 hypothetical protein compare
MMP_RS04615 -1.7 -3.2 PDGLE domain-containing protein compare
MMP_RS06485 -1.7 -0.9 zinc ribbon domain-containing protein compare
MMP_RS06285 -1.7 -2.2 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS04620 -1.7 -6.8 cobalt transporter CbiM compare
MMP_RS05875 -1.7 -3.3 hydroxyethylthiazole kinase compare
MMP_RS08210 -1.7 -1.7 phosphatidylglycerophosphatase A compare
MMP_RS05430 -1.6 -4.2 TIGR00288 family NYN domain-containing protein compare
MMP_RS06685 -1.6 -8.3 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS07575 -1.6 -3.9 RNA ligase partner protein compare
MMP_RS01985 -1.6 -3.9 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS02355 -1.6 -2.5 30S ribosomal protein S27ae compare
MMP_RS02175 -1.5 -0.7 DUF1611 domain-containing protein compare
MMP_RS08570 -1.5 -6.6 coenzyme F420-0:L-glutamate ligase compare
MMP_RS03580 -1.5 -2.6 signal recognition particle-docking protein FtsY compare
MMP_RS06315 -1.5 -0.8 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS07630 -1.5 -1.3 ATP-binding cassette domain-containing protein compare
MMP_RS04585 -1.5 -6.4 AIR synthase related protein compare
MMP_RS01800 -1.5 -2.5 TIGR00303 family protein compare
MMP_RS06730 -1.5 -1.5 phosphopantothenate/pantothenate synthetase compare
MMP_RS07600 -1.5 -1.4 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS05765 -1.5 -4.0 M42 family metallopeptidase compare
MMP_RS05245 -1.5 -7.1 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS06020 -1.5 -3.1 archaeoflavoprotein AfpA compare
MMP_RS06895 -1.5 -1.3 selenocysteine-specific translation elongation factor compare
MMP_RS03305 -1.4 -6.3 winged helix-turn-helix domain-containing protein compare
MMP_RS07735 -1.4 -0.7 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS01500 -1.4 -1.7 CBS domain-containing protein compare
MMP_RS06715 -1.4 -9.7 cache domain-containing protein compare
MMP_RS07380 -1.4 -1.6 transcription elongation factor Spt5 compare
MMP_RS02170 -1.3 -2.6 CBS domain-containing protein compare
MMP_RS06230 -1.3 -1.8 helix-turn-helix domain-containing protein compare
MMP_RS05540 -1.3 -3.3 hypothetical protein compare
MMP_RS02110 -1.3 -1.6 hypothetical protein compare
MMP_RS02345 -1.3 -2.5 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS06720 -1.3 -4.7 response regulator transcription factor compare
MMP_RS06525 -1.3 -1.0 YciI family protein compare
MMP_RS06925 -1.3 -1.4 ribonuclease VapC4 compare
MMP_RS08720 -1.2 -1.0 4Fe-4S binding protein compare
MMP_RS06475 -1.2 -3.4 FAD-dependent oxidoreductase compare
MMP_RS08225 -1.2 -4.8 RimK family alpha-L-glutamate ligase compare
MMP_RS06340 -1.2 -4.5 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS06270 -1.1 -3.0 TIGR00300 family protein compare
MMP_RS00320 -1.1 -1.2 class I SAM-dependent methyltransferase compare
MMP_RS07355 -1.1 -0.7 transcription factor S compare
MMP_RS03770 -1.1 -3.5 hydroxylamine reductase compare
MMP_RS03440 -1.1 -0.8 MoaD/ThiS family protein compare
MMP_RS08645 -1.1 -4.1 UPF0179 family protein compare
MMP_RS01750 -1.1 -4.6 DUF63 family protein compare
MMP_RS07730 -1.1 -1.2 pyruvate synthase subunit beta compare
MMP_RS06675 -1.1 -2.3 ADP-specific phosphofructokinase compare
MMP_RS03840 -1.1 -2.7 hypothetical protein compare
MMP_RS01265 -1.1 -1.2 hypothetical protein compare
MMP_RS02195 -1.1 -2.0 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS01830 -1.1 -1.1 tRNA-Val compare
MMP_RS01030 -1.1 -3.9 MTAP family purine nucleoside phosphorylase compare
MMP_RS00290 -1.1 -3.4 hypothetical protein compare
MMP_RS02165 -1.1 -3.8 tRNA-dihydrouridine synthase compare
MMP_RS03555 -1.1 -3.1 transcriptional regulator compare
MMP_RS00915 -1.1 -4.1 DUF116 domain-containing protein compare
MMP_RS00050 -1.0 -3.5 AarF/UbiB family protein compare
MMP_RS05420 -1.0 -2.8 DUF61 family protein compare
MMP_RS03470 -1.0 -3.6 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS01335 -1.0 -1.0 prefoldin subunit beta compare
MMP_RS00315 -1.0 -3.9 Nif3-like dinuclear metal center hexameric protein compare
MMP_RS04780 -1.0 -1.2 ribonuclease P compare
MMP_RS07765 -1.0 -4.8 sodium:alanine symporter family protein compare
MMP_RS00720 -1.0 -4.0 metal-dependent hydrolase compare
MMP_RS01385 -1.0 -0.4 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS03155 -1.0 -2.4 precorrin-6A reductase compare
MMP_RS00620 -1.0 -3.1 4Fe-4S binding protein compare
MMP_RS07200 -1.0 -2.4 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS01225 -1.0 -2.8 DUF5379 domain-containing protein compare
MMP_RS06855 -0.9 -3.0 hypothetical protein compare
MMP_RS03385 -0.9 -0.6 cation diffusion facilitator family transporter compare
MMP_RS01745 -0.9 -2.5 AMP phosphorylase compare
MMP_RS02875 -0.9 -4.4 chorismate pyruvate-lyase family protein compare
MMP_RS06870 -0.9 -2.8 DedA family protein compare
MMP_RS03400 -0.9 -1.4 archease compare
MMP_RS00895 -0.9 -1.6 hypothetical protein compare
MMP_RS01365 -0.9 -2.0 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS01220 -0.9 -2.6 hypothetical protein compare
MMP_RS06110 -0.9 -1.7 ATP-dependent protease LonB compare
MMP_RS04360 -0.9 -2.5 hypothetical protein compare
MMP_RS05460 -0.9 -3.4 YcaO-related McrA-glycine thioamidation protein compare
MMP_RS04870 -0.9 -2.0 TIGR02253 family HAD-type hydrolase compare
MMP_RS03025 -0.9 -2.1 molybdenum cofactor guanylyltransferase compare
MMP_RS01980 -0.9 -5.7 trimeric intracellular cation channel family protein compare
MMP_RS08165 -0.9 -1.3 phosphoglycerate dehydrogenase compare
MMP_RS04100 -0.9 -1.7 hypothetical protein compare
MMP_RS08300 -0.9 -0.7 metal-sulfur cluster assembly factor compare
MMP_RS00295 -0.9 -1.3 gamma carbonic anhydrase family protein compare
MMP_RS01325 -0.8 -0.8 dihydroneopterin aldolase family protein compare
MMP_RS02470 -0.8 -0.8 helix-turn-helix transcriptional regulator compare
MMP_RS06200 -0.8 -3.3 M24 family metallopeptidase compare
MMP_RS08725 -0.8 -1.2 Ni/Fe hydrogenase subunit alpha compare
MMP_RS01890 -0.8 -2.1 nucleotide sugar dehydrogenase compare
MMP_RS03780 -0.8 -2.5 4Fe-4S binding protein compare
MMP_RS04015 -0.8 -1.6 hypothetical protein compare
MMP_RS05925 -0.8 -1.3 small nuclear ribonucleoprotein compare
MMP_RS07640 -0.8 -2.0 mechanosensitive ion channel family protein compare
MMP_RS02480 -0.8 -1.1 hypothetical protein compare
MMP_RS04685 -0.8 -1.0 DUF126 domain-containing protein compare
MMP_RS08380 -0.8 -1.5 phosphatase PAP2 family protein compare
MMP_RS07420 -0.8 -2.5 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS05250 -0.7 -0.6 NFYB/HAP3 family transcription factor subunit compare
MMP_RS07365 -0.7 -3.6 2-phosphoglycerate kinase compare
MMP_RS08635 -0.7 -0.7 UbiA family prenyltransferase compare
MMP_RS03315 -0.7 -0.5 ferrous iron transport protein A compare
MMP_RS02975 -0.7 -2.5 DUF2124 domain-containing protein compare
MMP_RS00950 -0.7 -2.0 site-2 protease family protein compare
MMP_RS00035 -0.7 -3.6 DUF2098 family protein compare
MMP_RS06515 -0.7 -1.1 UPF0489 family protein compare
MMP_RS07540 -0.7 -1.4 CBS domain-containing protein compare
MMP_RS02780 -0.7 -3.4 hypothetical protein compare
MMP_RS02885 -0.7 -3.8 molybdopterin biosynthesis protein compare
MMP_RS05545 -0.7 -1.6 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS01470 -0.7 -1.5 ATP-binding cassette domain-containing protein compare
MMP_RS08280 -0.7 -1.3 proteasome assembly chaperone family protein compare
MMP_RS00810 -0.7 -2.2 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS06705 -0.7 -2.2 formate/nitrite transporter family protein compare
MMP_RS05505 -0.7 -3.1 class IV adenylate cyclase compare
MMP_RS08785 -0.7 -0.4 RNA-protein complex protein Nop10 compare
MMP_RS08930 -0.7 -0.9 hypothetical protein compare
MMP_RS02805 -0.7 -0.6 HEPN domain-containing protein compare
MMP_RS08830 -0.7 -2.0 GTP-binding protein compare
MMP_RS01720 -0.7 -0.8 replication factor C large subunit compare
MMP_RS07350 -0.7 -0.9 preprotein translocase subunit Sec61beta compare
MMP_RS06175 -0.7 -1.9 winged helix-turn-helix transcriptional regulator compare
MMP_RS00955 -0.7 -3.2 coenzyme gamma-F420-2:alpha-L-glutamate ligase compare
MMP_RS03205 -0.6 -0.5 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS00395 -0.6 -0.7 MGMT family protein compare
MMP_RS01685 -0.6 -1.3 indolepyruvate oxidoreductase subunit beta compare
MMP_RS02800 -0.6 -1.7 nucleotidyltransferase domain-containing protein compare
MMP_RS02380 -0.6 -1.8 ATP-binding protein compare
MMP_RS04335 -0.6 -3.3 GTP-binding protein compare
MMP_RS01155 -0.6 -2.6 XRE family transcriptional regulator compare
MMP_RS02500 -0.6 -2.6 minichromosome maintenance protein MCM compare
MMP_RS02595 -0.6 -0.6 putative zinc-binding protein compare
MMP_RS07535 -0.6 -2.2 4Fe-4S binding protein compare
MMP_RS03760 -0.6 -2.9 hypothetical protein compare
MMP_RS06710 -0.6 -1.4 selenium-binding protein compare


Specific Phenotypes

For 4 genes in this experiment

For stress Nitrofurantoin in Methanococcus maripaludis S2

For stress Nitrofurantoin across organisms