Experiment set5IT091 for Methanococcus maripaludis S2

Compare to:

Formate with Nitrofurantoin 0.25 mM

200 most important genes:

  gene name fitness t score description  
MMP_RS08720 -3.6 -1.7 4Fe-4S binding protein compare
MMP_RS05920 -3.5 -0.8 50S ribosomal protein L37e compare
MMP_RS01795 -3.1 -1.8 methanogenesis marker 6 protein compare
MMP_RS02235 -2.9 -16.6 CBS domain-containing protein compare
MMP_RS02240 -2.8 -4.0 methanogenesis marker 7 protein compare
MMP_RS06350 -2.6 -8.3 HesA/MoeB/ThiF family protein compare
MMP_RS07845 -2.5 -3.0 LL-diaminopimelate aminotransferase compare
MMP_RS00130 -2.5 -1.0 nickel-responsive transcriptional regulator NikR compare
MMP_RS08000 -2.3 -13.1 methyl coenzyme M reductase-arginine methyltransferase Mmp10 compare
MMP_RS03250 -2.3 -4.2 MJ1244 family protein compare
MMP_RS01665 -2.2 -5.0 DUF2111 domain-containing protein compare
MMP_RS08820 -2.2 -7.2 hypothetical protein compare
MMP_RS07635 -2.0 -6.6 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS07630 -2.0 -1.3 ATP-binding cassette domain-containing protein compare
MMP_RS04605 -1.9 -3.3 cobalt ECF transporter T component CbiQ compare
MMP_RS09020 -1.9 -1.6 hypothetical protein compare
MMP_RS06170 -1.9 -9.4 ABC transporter ATP-binding protein compare
MMP_RS08195 -1.8 -8.6 hypothetical protein compare
MMP_RS06400 -1.8 -1.4 4Fe-4S binding protein compare
MMP_RS05515 -1.8 -6.7 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS08210 -1.8 -2.3 phosphatidylglycerophosphatase A compare
MMP_RS01175 -1.7 -3.5 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS08165 -1.7 -2.4 phosphoglycerate dehydrogenase compare
MMP_RS06105 -1.7 -6.1 hydrogenase maturation peptidase HycI compare
MMP_RS04900 -1.7 -11.6 hypothetical protein compare
MMP_RS04615 -1.7 -3.0 PDGLE domain-containing protein compare
MMP_RS01610 -1.7 -2.5 hypothetical protein compare
MMP_RS07445 -1.7 -5.9 helix-turn-helix domain-containing protein compare
MMP_RS06355 -1.6 -2.6 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS06865 -1.6 -2.5 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS06295 -1.6 -5.8 methanogenesis marker 14 protein compare
MMP_RS03445 -1.6 -0.9 methanogenesis marker 17 protein compare
MMP_RS03015 -1.6 -7.3 GTP 3' 8-cyclase MoaA compare
MMP_RS06680 -1.6 -9.6 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS07730 -1.6 -1.5 pyruvate synthase subunit beta compare
MMP_RS00685 -1.6 -3.1 2-phospho-L-lactate guanylyltransferase compare
MMP_RS08200 -1.6 -10.6 archaeosine synthase subunit alpha compare
MMP_RS08745 -1.6 -5.7 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS05540 -1.6 -4.1 hypothetical protein compare
MMP_RS03600 -1.5 -1.7 triose-phosphate isomerase compare
MMP_RS05875 -1.5 -3.0 hydroxyethylthiazole kinase compare
MMP_RS06165 -1.5 -7.3 ABC transporter permease compare
MMP_RS08320 -1.5 -5.7 molybdopterin molybdotransferase MoeA compare
MMP_RS03775 -1.5 -3.6 4Fe-4S dicluster domain-containing protein compare
MMP_RS06345 -1.5 -8.1 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS04620 -1.5 -6.8 cobalt transporter CbiM compare
MMP_RS08725 -1.4 -1.6 Ni/Fe hydrogenase subunit alpha compare
MMP_RS06480 -1.4 -5.8 ABC transporter substrate-binding protein compare
MMP_RS05845 -1.4 -1.4 tRNA-intron lyase compare
MMP_RS08570 -1.4 -7.8 coenzyme F420-0:L-glutamate ligase compare
MMP_RS02355 -1.4 -2.4 30S ribosomal protein S27ae compare
MMP_RS04055 -1.4 -1.4 hypothetical protein compare
MMP_RS01800 -1.3 -2.4 TIGR00303 family protein compare
MMP_RS05355 -1.3 -0.7 hypothetical protein compare
MMP_RS00320 -1.3 -1.5 class I SAM-dependent methyltransferase compare
MMP_RS01100 -1.3 -1.4 ABC transporter ATP-binding protein compare
MMP_RS01005 -1.3 -1.0 riboflavin synthase compare
MMP_RS08225 -1.3 -5.6 RimK family alpha-L-glutamate ligase compare
MMP_RS01675 -1.3 -1.3 hypothetical protein compare
MMP_RS03580 -1.3 -2.6 signal recognition particle-docking protein FtsY compare
MMP_RS05865 -1.3 -2.8 hypothetical protein compare
MMP_RS04775 -1.3 -3.0 adenosylhomocysteinase compare
MMP_RS06340 -1.2 -5.3 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS00895 -1.2 -2.8 hypothetical protein compare
MMP_RS06175 -1.2 -3.9 winged helix-turn-helix transcriptional regulator compare
MMP_RS03440 -1.2 -0.9 MoaD/ThiS family protein compare
MMP_RS07525 -1.2 -6.3 4Fe-4S binding protein compare
MMP_RS03305 -1.2 -5.0 winged helix-turn-helix domain-containing protein compare
MMP_RS02170 -1.2 -3.4 CBS domain-containing protein compare
MMP_RS05430 -1.2 -5.2 TIGR00288 family NYN domain-containing protein compare
MMP_RS04305 -1.2 -1.9 hypothetical protein compare
MMP_RS03315 -1.1 -0.9 ferrous iron transport protein A compare
MMP_RS03770 -1.1 -4.0 hydroxylamine reductase compare
MMP_RS02470 -1.1 -1.1 helix-turn-helix transcriptional regulator compare
MMP_RS01325 -1.1 -1.4 dihydroneopterin aldolase family protein compare
MMP_RS07350 -1.1 -1.4 preprotein translocase subunit Sec61beta compare
MMP_RS01575 -1.1 -2.7 aldolase compare
MMP_RS08460 -1.1 -1.9 proteasome-activating nucleotidase compare
MMP_RS05415 -1.1 -2.4 DUF22 domain-containing protein compare
MMP_RS06525 -1.1 -1.0 YciI family protein compare
MMP_RS06710 -1.1 -2.1 selenium-binding protein compare
MMP_RS07115 -1.1 -3.7 MBL fold metallo-hydrolase compare
MMP_RS07540 -1.1 -2.4 CBS domain-containing protein compare
MMP_RS06020 -1.1 -3.2 archaeoflavoprotein AfpA compare
MMP_RS06700 -1.0 -5.9 hypothetical protein compare
MMP_RS03780 -1.0 -4.4 4Fe-4S binding protein compare
MMP_RS03025 -1.0 -3.7 molybdenum cofactor guanylyltransferase compare
MMP_RS08645 -1.0 -3.1 UPF0179 family protein compare
MMP_RS06200 -1.0 -4.6 M24 family metallopeptidase compare
MMP_RS01265 -1.0 -1.5 hypothetical protein compare
MMP_RS04890 -1.0 -0.5 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS03555 -1.0 -3.2 transcriptional regulator compare
MMP_RS02790 -1.0 -0.7 class III signal peptide-containing protein compare
MMP_RS03470 -1.0 -4.4 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS06675 -1.0 -3.9 ADP-specific phosphofructokinase compare
MMP_RS06280 -1.0 -3.2 alpha-glucan family phosphorylase compare
MMP_RS01985 -1.0 -2.5 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS06475 -1.0 -3.0 FAD-dependent oxidoreductase compare
MMP_RS00695 -0.9 -0.6 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS02975 -0.9 -2.8 DUF2124 domain-containing protein compare
MMP_RS01220 -0.9 -2.9 hypothetical protein compare
MMP_RS06855 -0.9 -5.0 hypothetical protein compare
MMP_RS08715 -0.9 -0.9 formylmethanofuran dehydrogenase subunit B compare
MMP_RS00115 -0.9 -4.1 radical SAM protein compare
MMP_RS01020 -0.9 -0.6 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS05925 -0.9 -2.1 small nuclear ribonucleoprotein compare
MMP_RS02110 -0.9 -1.2 hypothetical protein compare
MMP_RS03965 -0.9 -1.4 hypothetical protein compare
MMP_RS07600 -0.9 -0.9 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS05765 -0.8 -3.3 M42 family metallopeptidase compare
MMP_RS04090 -0.8 -1.7 hypothetical protein compare
MMP_RS06315 -0.8 -0.5 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS08415 -0.8 -2.1 radical SAM protein compare
MMP_RS08280 -0.8 -1.6 proteasome assembly chaperone family protein compare
MMP_RS02175 -0.8 -0.5 DUF1611 domain-containing protein compare
MMP_RS02165 -0.8 -3.2 tRNA-dihydrouridine synthase compare
MMP_RS02345 -0.8 -1.8 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS01195 -0.8 -0.7 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS04685 -0.8 -1.1 DUF126 domain-containing protein compare
MMP_RS06730 -0.8 -0.8 phosphopantothenate/pantothenate synthetase compare
MMP_RS00035 -0.8 -3.8 DUF2098 family protein compare
MMP_RS06285 -0.8 -1.4 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS03960 -0.8 -0.4 hypothetical protein compare
MMP_RS05545 -0.8 -1.6 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS02495 -0.8 -1.5 hypothetical protein compare
MMP_RS08435 -0.8 -0.9 Era-like GTP-binding protein compare
MMP_RS04585 -0.8 -3.3 AIR synthase related protein compare
MMP_RS08240 -0.8 -2.2 methanogenesis marker 16 metalloprotein compare
MMP_RS00290 -0.7 -2.6 hypothetical protein compare
MMP_RS05955 -0.7 -1.3 CoB--CoM heterodisulfide reductase subunit C compare
MMP_RS02595 -0.7 -0.8 putative zinc-binding protein compare
MMP_RS06685 -0.7 -4.2 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS01750 -0.7 -3.4 DUF63 family protein compare
MMP_RS08915 -0.7 -1.8 2 5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase compare
MMP_RS04870 -0.7 -1.7 TIGR02253 family HAD-type hydrolase compare
MMP_RS02885 -0.7 -3.9 molybdopterin biosynthesis protein compare
MMP_RS02780 -0.7 -3.5 hypothetical protein compare
MMP_RS00720 -0.7 -3.0 metal-dependent hydrolase compare
MMP_RS01140 -0.7 -1.7 molybdate ABC transporter permease subunit compare
MMP_RS07895 -0.7 -1.6 cytochrome c compare
MMP_RS00395 -0.7 -0.8 MGMT family protein compare
MMP_RS01085 -0.7 -0.8 hypothetical protein compare
MMP_RS06870 -0.7 -1.5 DedA family protein compare
MMP_RS03210 -0.6 -4.0 tRNA guanosine(15) transglycosylase TgtA compare
MMP_RS02835 -0.6 -1.4 CGGC domain-containing protein compare
MMP_RS04955 -0.6 -2.2 DNA topoisomerase I compare
MMP_RS08830 -0.6 -2.0 GTP-binding protein compare
MMP_RS02800 -0.6 -2.7 nucleotidyltransferase domain-containing protein compare
MMP_RS06925 -0.6 -0.8 ribonuclease VapC4 compare
MMP_RS04325 -0.6 -2.4 MtaA/CmuA family methyltransferase compare
MMP_RS06365 -0.6 -1.0 hypothetical protein compare
MMP_RS02805 -0.6 -0.6 HEPN domain-containing protein compare
MMP_RS03090 -0.6 -3.0 cation:proton antiporter compare
MMP_RS02280 -0.6 -0.4 DUF211 domain-containing protein compare
MMP_RS08215 -0.6 -1.1 DUF483 domain-containing protein compare
MMP_RS04610 -0.6 -1.4 Dabb family protein compare
MMP_RS09050 -0.6 -1.6 CAP domain-containing protein compare
MMP_RS02875 -0.6 -2.8 chorismate pyruvate-lyase family protein compare
MMP_RS01365 -0.6 -1.4 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS00950 -0.6 -1.5 site-2 protease family protein compare
MMP_RS07575 -0.6 -1.2 RNA ligase partner protein compare
MMP_RS00670 -0.6 -1.7 TIM barrel protein compare
MMP_RS04780 -0.6 -0.8 ribonuclease P compare
MMP_RS01470 -0.6 -1.4 ATP-binding cassette domain-containing protein compare
MMP_RS00110 -0.6 -1.0 hypothetical protein compare
MMP_RS06435 -0.6 -1.9 CBS domain-containing protein compare
MMP_RS00570 -0.5 -0.9 protein-L-isoaspartate O-methyltransferase compare
MMP_RS05420 -0.5 -1.0 DUF61 family protein compare
MMP_RS03760 -0.5 -2.4 hypothetical protein compare
MMP_RS07840 -0.5 -0.7 ribonuclease III compare
MMP_RS07735 -0.5 -0.4 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS07645 -0.5 -2.6 aldehyde dehydrogenase family protein compare
MMP_RS03350 -0.5 -1.4 winged helix-turn-helix domain-containing protein compare
MMP_RS02785 -0.5 -2.0 MarR family transcriptional regulator compare
MMP_RS00515 -0.5 -0.4 DUF655 domain-containing protein compare
MMP_RS01095 -0.5 -1.1 iron ABC transporter permease compare
MMP_RS03400 -0.5 -1.1 archease compare
MMP_RS02935 -0.5 -1.7 A24 family peptidase compare
MMP_RS04485 -0.5 -3.4 putative beta-lysine N-acetyltransferase compare
MMP_RS00960 -0.5 -1.0 iron export ABC transporter permease subunit FetB compare
MMP_RS08845 -0.5 -2.5 archaellum operon transcriptional activator EarA family protein compare
MMP_RS01030 -0.5 -1.0 MTAP family purine nucleoside phosphorylase compare
MMP_RS03155 -0.5 -2.0 precorrin-6A reductase compare
MMP_RS01835 -0.5 -1.9 hypothetical protein compare
MMP_RS07380 -0.5 -0.6 transcription elongation factor Spt5 compare
MMP_RS07535 -0.5 -2.3 4Fe-4S binding protein compare
MMP_RS07385 -0.5 -0.9 protein translocase SEC61 complex subunit gamma compare
MMP_RS03020 -0.5 -1.7 peptidylprolyl isomerase compare
MMP_RS07420 -0.5 -1.7 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS05460 -0.5 -2.4 YcaO-related McrA-glycine thioamidation protein compare
MMP_RS05315 -0.5 -0.7 hypothetical protein compare
MMP_RS00810 -0.5 -1.8 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS06485 -0.5 -0.4 zinc ribbon domain-containing protein compare
MMP_RS01385 -0.5 -0.2 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS00050 -0.5 -1.6 AarF/UbiB family protein compare
MMP_RS03740 -0.5 -1.2 indolepyruvate oxidoreductase subunit beta compare
MMP_RS07200 -0.5 -1.3 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS05245 -0.5 -2.8 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS05990 -0.5 -0.9 DsrE family protein compare
MMP_RS00400 -0.5 -1.7 tributyrin esterase compare


Specific Phenotypes

For 3 genes in this experiment

For stress Nitrofurantoin in Methanococcus maripaludis S2

For stress Nitrofurantoin across organisms