Experiment set5IT090 for Rhodospirillum rubrum S1H

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L-Malic Acid acid carbon source with ammonium chloride; no light

200 most important genes:

  gene name fitness t score description  
Rru_A3594 -3.5 -6.0 Histidine biosynthesis protein HisF (NCBI) compare
Rru_A3267 -2.9 -7.3 Methionine biosynthesis MetW (NCBI) compare
Rru_A3571 -2.7 -3.6 Glycerol-3-phosphate dehydrogenase (NAD(P)+) (NCBI) compare
Rru_A0432 -2.6 -5.9 4-hydroxythreonine-4-phosphate dehydrogenase (NCBI) compare
Rru_A3427 -2.6 -13.0 Tryptophan synthase, beta chain (NCBI) compare
Rru_A2885 -2.5 -11.6 Carbamoyl-phosphate synthase, small subunit (NCBI) compare
Rru_A3428 -2.5 -9.8 Tryptophan synthase (NCBI) compare
Rru_A1530 -2.5 -15.3 5,10-methylenetetrahydrofolate reductase (NCBI) compare
Rru_A2886 -2.4 -14.1 Carbamoyl-phosphate synthase, large subunit, glutamine-dependent (NCBI) compare
Rru_A1239 -2.4 -3.8 Glutamate 5-kinase, ProB-related (NCBI) compare
Rru_A1897 -2.4 -4.1 Indole-3-glycerol-phosphate synthase (NCBI) compare
Rru_A1189 -2.3 -9.3 3-isopropylmalate dehydratase large subunit region (NCBI) compare
Rru_A1854 -2.3 -6.2 Pyridoxal phosphate biosynthetic protein PdxJ (NCBI) compare
Rru_A0468 -2.3 -2.3 Acetolactate synthase, small subunit (NCBI) compare
Rru_A3642 -2.3 -3.5 Negative regulator of class I heat shock protein (NCBI) compare
Rru_A0469 -2.3 -8.1 Ketol-acid reductoisomerase (NCBI) compare
Rru_A1620 -2.3 -3.9 hypothetical protein (NCBI) compare
Rru_A1105 -2.2 -4.0 tRNA synthetase, class II (G, H, P and S) (NCBI) compare
Rru_A1771 -2.2 -0.6 Sec-independent periplasmic protein translocase (NCBI) compare
Rru_A2574 -2.2 -1.1 Transcriptional Regulator, BadM/Rrf2 family (NCBI) compare
Rru_A3276 -2.1 -3.2 Ornithine carbamoyltransferase (NCBI) compare
Rru_A0467 -2.1 -8.5 Acetolactate synthase, large subunit, biosynthetic type (NCBI) compare
Rru_A1827 -2.0 -7.8 Glycine hydroxymethyltransferase (NCBI) compare
Rru_A3162 -2.0 -7.7 Prephenate dehydratase (NCBI) compare
Rru_A2771 -2.0 -3.7 Histidinol dehydrogenase (NCBI) compare
Rru_A0644 -2.0 -7.8 hypothetical protein (NCBI) compare
Rru_A3214 -1.9 -7.0 O-succinylhomoserine sulfhydrylase (NCBI) compare
Rru_A0058 -1.9 -2.4 Dihydrokaempferol 4-reductase (NCBI) compare
Rru_A3380 -1.9 -2.4 hypothetical protein (NCBI) compare
Rru_A1593 -1.9 -6.2 Peptidase M50, putative membrane-associated zinc metallopeptidase (NCBI) compare
Rru_A1786 -1.9 -9.7 Dihydroxy-acid dehydratase (NCBI) compare
Rru_A0397 -1.9 -3.1 Argininosuccinate lyase (NCBI) compare
Rru_A3202 -1.8 -11.7 DNA topoisomerase (NCBI) compare
Rru_A3751 -1.8 -5.1 Argininosuccinate synthase (NCBI) compare
Rru_A3165 -1.7 -3.2 Histidinol-phosphate phosphatase, putative, inositol monophosphatase (NCBI) compare
Rru_A2772 -1.7 -1.3 ATP phosphoribosyltransferase (NCBI) compare
Rru_B0040 -1.7 -12.7 Type I secretion membrane fusion protein, HlyD (NCBI) compare
Rru_A3277 -1.7 -3.4 Acetylornithine and succinylornithine aminotransferase (NCBI) compare
Rru_A2656 -1.7 -1.8 ATP12 ATPase (NCBI) compare
Rru_A1675 -1.7 -7.6 Cytochrome c assembly protein (NCBI) compare
Rru_A1798 -1.6 -7.0 Type I secretion outer membrane protein, TolC (NCBI) compare
Rru_A3240 -1.6 -1.5 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain (NCBI) compare
Rru_A3190 -1.6 -2.4 Aspartate carbamoyltransferase (NCBI) compare
Rru_A2285 -1.6 -1.5 Nitrogenase molybdenum-iron cofactor biosynthesis protein (NCBI) compare
Rru_A1258 -1.5 -1.8 hypothetical protein (NCBI) compare
Rru_A0514 -1.5 -5.7 Dihydroorotate dehydrogenase 2 (NCBI) compare
Rru_A0963 -1.5 -1.7 MifU-like protein, Fe-S cluster formation (NCBI) compare
Rru_A3266 -1.5 -4.8 Homoserine O-acetyltransferase (NCBI) compare
Rru_A1445 -1.5 -5.3 Ribonucleoside-diphosphate reductase (NCBI) compare
Rru_A1928 -1.5 -5.0 Yeast 2-isopropylmalate synthase (NCBI) compare
Rru_A0329 -1.5 -1.8 hypothetical protein (NCBI) compare
Rru_A1839 -1.4 -2.2 TRAP-type C4-dicarboxylate transport system periplasmic component-like (NCBI) compare
Rru_A1865 -1.4 -4.0 Dihydrodipicolinate synthase subfamily (NCBI) compare
Rru_A1718 -1.4 -8.9 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase (NCBI) compare
Rru_A3596 -1.4 -2.2 Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit (NCBI) compare
Rru_B0005 -1.4 -2.6 Glycosyl transferase (NCBI) compare
Rru_B0039 -1.4 -11.3 Type I secretion system ATPase, PrtD (NCBI) compare
Rru_B0022 -1.4 -0.6 Resolvase-like (NCBI) compare
Rru_B0037 -1.3 -11.9 Hemolysin-type calcium-binding region (NCBI) compare
Rru_A1194 -1.3 -1.8 Protein of unknown function DUF134 (NCBI) compare
Rru_A2507 -1.3 -6.9 Orotate phosphoribosyl transferase (NCBI) compare
Rru_A2936 -1.3 -4.0 Dihydroorotase multifunctional complex type (NCBI) compare
Rru_A2201 -1.3 -1.9 Peptidase S1C, Do (NCBI) compare
Rru_A1310 -1.3 -4.8 Acetyl-CoA C-acyltransferase (NCBI) compare
Rru_A2715 -1.3 -6.7 Acyltransferase 3 (NCBI) compare
Rru_A3378 -1.3 -3.0 hypothetical protein (NCBI) compare
Rru_A3614 -1.2 -2.4 Maf-like protein (NCBI) compare
Rru_B0028 -1.2 -1.8 ABC transporter related (NCBI) compare
Rru_A3783 -1.2 -5.7 tRNA pseudouridine synthase B (NCBI) compare
Rru_A3191 -1.2 -6.2 Dihydroorotase multifunctional complex type (NCBI) compare
Rru_A1191 -1.2 -3.7 3-isopropylmalate dehydrogenase (NCBI) compare
Rru_A3393 -1.2 -3.2 Penicillin-binding protein 1A (NCBI) compare
Rru_A0574 -1.2 -2.8 Carboxylyase-related protein (NCBI) compare
Rru_A1837 -1.2 -3.4 Porphobilinogen synthase (NCBI) compare
Rru_A1896 -1.1 -2.2 Anthranilate phosphoribosyl transferase (NCBI) compare
Rru_A0667 -1.1 -2.9 Nicotinate-nucleotide-dimethylbenzimidazolephosphoribosyltransferase (NCBI) compare
Rru_A1444 -1.1 -3.4 Ribonucleoside-diphosphate reductase (NCBI) compare
Rru_A1435 -1.1 -3.5 Two Component, Sigma54 Specific, Transcriptional Regulator, Fis family (NCBI) compare
Rru_A3398 -1.0 -1.3 Transcriptional Regulator, XRE family (NCBI) compare
Rru_A1308 -1.0 -7.1 Acyl-CoA dehydrogenase (NCBI) compare
Rru_B0043 -1.0 -2.7 hypothetical protein (NCBI) compare
Rru_A1021 -1.0 -2.9 Sigma 32 (RpoH) (NCBI) compare
Rru_A3424 -1.0 -1.5 Orotidine-5'-phosphate decarboxylase (NCBI) compare
Rru_A3626 -1.0 -0.9 Glucose inhibited division protein (NCBI) compare
Rru_A1436 -1.0 -4.1 Histidine Kinase (NCBI) compare
Rru_A0909 -1.0 -2.3 Propanediol utilization protein (NCBI) compare
Rru_A3256 -1.0 -3.0 Protein of unknown function DUF218 (NCBI) compare
Rru_A3627 -1.0 -2.7 Cobyrinic acid a,c-diamide synthase (NCBI) compare
Rru_A3766 -0.9 -3.1 Transcriptional Regulator, MucR family (NCBI) compare
Rru_A1527 -0.9 -2.5 ABC transporter component (NCBI) compare
Rru_A1085 -0.9 -1.9 Metallophosphoesterase (NCBI) compare
Rru_A1797 -0.9 -4.2 hypothetical protein (NCBI) compare
Rru_A0847 -0.9 -1.3 PepSY-associated TM helix (NCBI) compare
Rru_A3640 -0.9 -0.5 Ham1-like protein (NCBI) compare
Rru_A0296 -0.9 -1.5 hypothetical protein (NCBI) compare
Rru_A3264 -0.9 -3.0 Histidinol-phosphate aminotransferase (NCBI) compare
Rru_A0852 -0.9 -3.9 hypothetical protein (NCBI) compare
Rru_A2351 -0.9 -4.6 Macrocin-O-methyltransferase (NCBI) compare
Rru_A3003 -0.9 -3.0 Transcriptional Regulator, GntR family (NCBI) compare
Rru_A2866 -0.9 -2.9 Ribosomal protein L11 methyltransferase (NCBI) compare
Rru_A2549 -0.9 -2.3 HAD-superfamily hydrolase subfamily IIB (NCBI) compare
Rru_A1883 -0.8 -1.3 Magnesium and cobalt transport protein CorA (NCBI) compare
Rru_A1309 -0.8 -5.3 acetoacetyl-CoA reductase (NCBI) compare
Rru_A3693 -0.8 -2.3 Protein of unknown function UPF0011 (NCBI) compare
Rru_A3268 -0.8 -1.7 hypothetical protein (NCBI) compare
Rru_A1434 -0.8 -4.1 Quinolinate synthetase A (NCBI) compare
Rru_A2085 -0.8 -1.6 Nitrogen regulatory protein P-II (GlnB, GlnK) (NCBI) compare
Rru_A2411 -0.8 -3.6 Aminotransferase, class I and II (NCBI) compare
Rru_A0521 -0.8 -4.1 CheA Signal Transduction Histidine Kinases (STHK) (NCBI) compare
Rru_A0702 -0.8 -2.7 Molybdate ABC transporter, ATP-binding protein (NCBI) compare
Rru_A1432 -0.8 -4.4 Nicotinate-nucleotide pyrophosphorylase (NCBI) compare
Rru_A2396 -0.8 -1.5 Putative FecR (NCBI) compare
Rru_A3532 -0.8 -2.8 UspA (NCBI) compare
Rru_A0556 -0.8 -3.8 Formyltetrahydrofolate deformylase (NCBI) compare
Rru_A1016 -0.8 -4.3 Binding-protein-dependent transport systems inner membrane component (NCBI) compare
Rru_A3755 -0.8 -4.0 Heat shock protein Hsp20 (NCBI) compare
Rru_A2184 -0.8 -0.3 Pyridoxamine 5'-phosphate oxidase-related, FMN-binding (NCBI) compare
Rru_A2800 -0.8 -1.4 hypothetical protein (NCBI) compare
Rru_A2199 -0.8 -2.9 hypothetical protein (NCBI) compare
Rru_A3512 -0.8 -3.7 Glutamine amidotransferase class-I (NCBI) compare
Rru_A1348 -0.8 -1.2 Protein of unknown function DUF81 (NCBI) compare
Rru_A2345 -0.8 -4.8 Glycosyl transferase, group 1 (NCBI) compare
Rru_A1911 -0.8 -2.3 Ferric uptake regulator (FUR) family (NCBI) compare
Rru_A2424 -0.8 -2.6 Gamma-glutamyltranspeptidase (NCBI) compare
Rru_A3623 -0.8 -1.1 hypothetical protein (NCBI) compare
Rru_A1265 -0.8 -2.7 Transcriptional Regulator, DeoR family (NCBI) compare
Rru_A3020 -0.7 -0.3 hypothetical protein (NCBI) compare
Rru_B0042 -0.7 -2.0 hypothetical protein (NCBI) compare
Rru_A3023 -0.7 -3.4 hypothetical protein (NCBI) compare
Rru_A0643 -0.7 -4.0 Protein of unknown function DUF152 (NCBI) compare
Rru_A0737 -0.7 -2.0 Phosphoribosyltransferase (NCBI) compare
Rru_A0657 -0.7 -2.4 Lysine exporter protein (LYSE/YGGA) (NCBI) compare
Rru_A2140 -0.7 -3.3 Transcriptional Regulator, XRE family (NCBI) compare
Rru_A1055 -0.7 -1.5 Protein of unknown function DUF1013 (NCBI) compare
Rru_A2455 -0.7 -1.2 hypothetical protein (NCBI) compare
Rru_A2749 -0.7 -2.4 Protein of unknown function DUF214 (NCBI) compare
Rru_A2190 -0.7 -1.4 TRm3 transposase (NCBI) compare
Rru_A0585 -0.7 -1.1 ABC transporter component (NCBI) compare
Rru_A2761 -0.7 -1.4 Acyltransferase 3 (NCBI) compare
Rru_A3797 -0.7 -3.3 2-polyprenylphenol 6-hydroxylase (NCBI) compare
Rru_A3383 -0.7 -2.4 Cobalamin (vitamin B12) biosynthesis CbiG protein (NCBI) compare
Rru_A1015 -0.7 -1.1 Binding-protein-dependent transport systems inner membrane component (NCBI) compare
Rru_A0740 -0.7 -2.0 Protein of unknown function DUF1178 (NCBI) compare
Rru_A1687 -0.7 -1.0 Inositol monophosphatase (NCBI) compare
Rru_A2703 -0.7 -2.4 RNA methyltransferase TrmH, group 3 (NCBI) compare
Rru_A3552 -0.7 -0.7 hypothetical protein (NCBI) compare
Rru_A2303 -0.7 -2.4 Deoxyribose-phosphate aldolase (NCBI) compare
Rru_A1627 -0.7 -1.4 hypothetical protein (NCBI) compare
Rru_A2349 -0.7 -4.0 hypothetical protein (NCBI) compare
Rru_A3338 -0.7 -2.4 Protein of unknown function DUF37 (NCBI) compare
Rru_A0236 -0.7 -2.0 Camphor resistance CrcB protein (NCBI) compare
Rru_A2347 -0.7 -4.3 hypothetical protein (NCBI) compare
Rru_A0448 -0.7 -3.4 Protein of unknown function DUF52 (NCBI) compare
Rru_A0986 -0.7 -2.6 hypothetical protein (NCBI) compare
Rru_A0213 -0.6 -1.3 hypothetical protein (NCBI) compare
Rru_A0902 -0.6 -2.8 Peptidase C56, PfpI (NCBI) compare
Rru_A0325 -0.6 -1.5 Molybdenum cofactor biosynthesis protein (NCBI) compare
Rru_A2141 -0.6 -3.4 Protein of unknown function DUF6, transmembrane (NCBI) compare
Rru_A2538 -0.6 -1.8 hypothetical protein (NCBI) compare
Rru_A2603 -0.6 -2.3 Two Component Transcriptional Regulator, LuxR family (NCBI) compare
Rru_A0010 -0.6 -1.0 Sigma-54 (RpoN) (NCBI) compare
Rru_A0089 -0.6 -4.0 ATP-dependent DNA helicase RecQ (NCBI) compare
Rru_A3197 -0.6 -2.7 HicB (NCBI) compare
Rru_A1413 -0.6 -1.5 Protein of unknown function DUF224, cysteine-rich region (NCBI) compare
Rru_A1334 -0.6 -2.5 Ribose 5-phosphate isomerase B (NCBI) compare
Rru_A1437 -0.6 -2.2 Sodium:dicarboxylate symporter (NCBI) compare
Rru_A2118 -0.6 -2.8 ATPase (NCBI) compare
Rru_A1014 -0.6 -1.0 hypothetical protein (NCBI) compare
Rru_A1855 -0.6 -3.0 hypothetical protein (NCBI) compare
Rru_A1959 -0.6 -2.1 Radical SAM (NCBI) compare
Rru_A1111 -0.6 -3.3 Pseudouridine synthase, RluD (NCBI) compare
Rru_A2137 -0.6 -1.6 Protein of unknown function DUF847 (NCBI) compare
Rru_A3188 -0.6 -2.4 Histidine Kinase (NCBI) compare
Rru_A0073 -0.6 -1.9 ribosomal subunit interface protein, putative (NCBI) compare
Rru_A2519 -0.6 -1.4 Protein of unknown function UPF0057 (NCBI) compare
Rru_A3782 -0.6 -1.3 Ribosome-binding factor A (NCBI) compare
Rru_A1649 -0.6 -1.2 hypothetical protein (NCBI) compare
Rru_A2242 -0.6 -1.0 Glutathione-dependent formaldehyde-activating, GFA (NCBI) compare
Rru_A2348 -0.6 -3.7 Glycosyl transferase (NCBI) compare
Rru_A2161 -0.6 -4.6 Polyphosphate kinase (NCBI) compare
Rru_A2493 -0.6 -2.3 Glycosyl transferase, group 1 (NCBI) compare
Rru_A1507 -0.6 -2.3 short-chain dehydrogenase/reductase SDR (NCBI) compare
Rru_A1776 -0.6 -1.3 Peptidase M50 (NCBI) compare
Rru_A2194 -0.6 -1.1 MaoC-like dehydratase (NCBI) compare
Rru_A1454 -0.6 -2.0 Phage Tail Collar (NCBI) compare
Rru_A3173 -0.6 -1.0 Transcriptional Regulator, TetR family (NCBI) compare
Rru_A2193 -0.6 -3.9 Abc1 protein (NCBI) compare
Rru_A1170 -0.6 -1.1 Two Component, Sigma54 Specific, Transcriptional Regulator, Fis family (NCBI) compare
Rru_A0253 -0.6 -3.2 GDP-mannose 4,6-dehydratase (NCBI) compare
Rru_A1829 -0.6 -3.9 Transcriptional Regulator, MucR family (NCBI) compare
Rru_A1501 -0.6 -2.0 Transport-associated (NCBI) compare
Rru_A0162 -0.6 -2.3 Chaperonin Cpn60/TCP-1 (NCBI) compare
Rru_A3119 -0.5 -1.9 ATPases involved in chromosome partitioning-like (NCBI) compare
Rru_A2512 -0.5 -1.0 3-oxoacyl-(acyl-carrier-protein) reductase (NCBI) compare
Rru_A2503 -0.5 -3.4 Hydroxypyruvate isomerase (NCBI) compare
Rru_A3010 -0.5 -2.4 Transcriptional Regulator, DeoR family (NCBI) compare
Rru_A1209 -0.5 -1.3 Chromate transporter (NCBI) compare
Rru_A2224 -0.5 -0.7 Transcriptional Regulator, MarR family (NCBI) compare
Rru_A2826 -0.5 -2.6 Flagellar basal-body rod protein FlgB (NCBI) compare
Rru_A0617 -0.5 -2.3 Photosynthetic reaction center, H-chain (NCBI) compare


Specific Phenotypes

For 8 genes in this experiment

For anaerboic nitrogen source Ammonium chloride in Rhodospirillum rubrum S1H

For anaerboic nitrogen source Ammonium chloride across organisms