Experiment set5IT090 for Methanococcus maripaludis S2

Compare to:

Formate with Nalidixic acid 12.5 mM

200 most detrimental genes:

  gene name fitness t score description  
MMP_RS01775 +1.0 3.3 TIGR00297 family protein compare
MMP_RS02310 +0.6 2.2 RimK-like ATPgrasp N-terminal domain-containing protein compare
MMP_RS00945 +0.5 1.3 PadR family transcriptional regulator compare
MMP_RS01370 +0.5 3.7 acetate--CoA ligase family protein compare
MMP_RS00825 +0.5 3.0 fumarylacetoacetate hydrolase family protein compare
MMP_RS08370 +0.5 0.7 cation:proton antiporter subunit C compare
MMP_RS07820 +0.5 1.8 UPF0104 family protein compare
MMP_RS07130 +0.5 3.7 coenzyme F420 hydrogenase subunit gamma compare
MMP_RS09035 +0.4 1.7 hypothetical protein compare
MMP_RS07125 +0.4 2.5 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS07875 +0.4 2.7 hypothetical protein compare
MMP_RS06535 +0.4 1.9 2-oxoacid:acceptor oxidoreductase family protein compare
MMP_RS05580 +0.4 3.7 glycosyltransferase compare
MMP_RS03465 +0.4 1.0 adenine phosphoribosyltransferase compare
MMP_RS08310 +0.4 1.6 TMEM165/GDT1 family protein compare
MMP_RS06530 +0.4 2.4 bifunctional hexulose-6-phosphate synthase/ribonuclease regulator compare
MMP_RS06600 +0.4 1.2 class III signal peptide-containing protein compare
MMP_RS00530 +0.4 2.8 tRNA pseudouridine(54/55) synthase Pus10 compare
MMP_RS06460 +0.4 2.2 pyrimidine dimer DNA glycosylase/endonuclease V compare
MMP_RS06485 +0.3 0.8 zinc ribbon domain-containing protein compare
MMP_RS05345 +0.3 1.9 hypothetical protein compare
MMP_RS07115 +0.3 2.6 MBL fold metallo-hydrolase compare
MMP_RS06435 +0.3 2.1 CBS domain-containing protein compare
MMP_RS06545 +0.3 2.2 ferredoxin family protein compare
MMP_RS05990 +0.3 2.3 DsrE family protein compare
MMP_RS07925 +0.3 1.4 haloacid dehalogenase compare
MMP_RS02790 +0.3 0.8 class III signal peptide-containing protein compare
MMP_RS01570 +0.3 1.0 hypothetical protein compare
MMP_RS02675 +0.3 0.8 hypothetical protein compare
MMP_RS08620 +0.3 1.7 flagellar accessory protein FlaH compare
MMP_RS01575 +0.3 2.0 aldolase compare
MMP_RS01745 +0.3 1.9 AMP phosphorylase compare
MMP_RS00140 +0.3 1.6 DUF192 domain-containing protein compare
MMP_RS01525 +0.3 1.1 nucleoside-diphosphate kinase compare
MMP_RS04520 +0.3 1.5 nucleoside deaminase compare
MMP_RS03800 +0.3 1.9 hypothetical protein compare
MMP_RS07120 +0.3 2.1 coenzyme F420 hydrogenase subunit alpha compare
MMP_RS01650 +0.3 0.7 sulfurtransferase TusA family protein compare
MMP_RS07345 +0.3 1.4 glycine synthesis protein GlyXL (from data) compare
MMP_RS04790 +0.3 2.2 4-hydroxy-tetrahydrodipicolinate reductase compare
MMP_RS07890 +0.3 0.7 OB-fold nucleic acid binding domain-containing protein compare
MMP_RS01620 +0.3 1.7 hypothetical protein compare
MMP_RS02590 +0.3 2.2 low molecular weight phosphatase family protein compare
MMP_RS02455 +0.3 2.1 hypothetical protein compare
MMP_RS07540 +0.3 1.4 CBS domain-containing protein compare
MMP_RS05715 +0.3 1.8 hypothetical protein compare
MMP_RS01605 +0.3 1.8 hypothetical protein compare
MMP_RS07135 +0.3 1.9 coenzyme F420 hydrogenase subunit beta compare
MMP_RS01470 +0.2 1.5 ATP-binding cassette domain-containing protein compare
MMP_RS08600 +0.2 1.0 flagellar protein D compare
MMP_RS08470 +0.2 1.9 ATP-binding cassette domain-containing protein compare
MMP_RS05720 +0.2 1.4 signal recognition particle subunit SRP19/SEC65 family protein compare
MMP_RS08760 +0.2 1.0 hypothetical protein compare
MMP_RS04265 +0.2 1.2 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS06725 +0.2 1.6 hypothetical protein compare
MMP_RS06480 +0.2 1.9 ABC transporter substrate-binding protein compare
MMP_RS06660 +0.2 1.8 glycosyltransferase family 4 protein compare
MMP_RS02360 +0.2 1.6 hypothetical protein compare
MMP_RS00450 +0.2 0.6 4Fe-4S binding protein compare
MMP_RS04740 +0.2 1.6 DUF473 domain-containing protein compare
MMP_RS08775 +0.2 1.3 methanogenesis marker 9 domain-containing protein compare
MMP_RS08945 +0.2 1.8 hypothetical protein compare
MMP_RS08265 +0.2 1.1 rubrerythrin compare
MMP_RS02550 +0.2 1.1 helix-turn-helix transcriptional regulator compare
MMP_RS06495 +0.2 0.7 YkgJ family cysteine cluster protein compare
MMP_RS06165 +0.2 1.6 ABC transporter permease compare
MMP_RS05665 +0.2 1.4 phosphate ABC transporter permease subunit PstC compare
MMP_RS04145 +0.2 0.8 hypothetical protein compare
MMP_RS08315 +0.2 0.8 S-methyl-5-thioribose-1-phosphate isomerase compare
MMP_RS03300 +0.2 0.4 TOBE domain-containing protein compare
MMP_RS08705 +0.2 1.2 sulfopyruvate decarboxylase subunit beta compare
MMP_RS07410 +0.2 1.8 4-demethylwyosine synthase TYW1 compare
MMP_RS08215 +0.2 0.9 DUF483 domain-containing protein compare
MMP_RS03150 +0.2 1.7 phosphoglycerate mutase compare
MMP_RS03130 +0.2 1.2 hypothetical protein compare
MMP_RS02320 +0.2 1.6 glutamate-cysteine ligase family protein compare
MMP_RS02775 +0.2 1.7 hypothetical protein compare
MMP_RS00740 +0.2 0.8 cyclase family protein compare
MMP_RS06430 +0.2 1.3 6-carboxytetrahydropterin synthase QueD compare
MMP_RS01145 +0.2 1.5 ABC transporter ATP-binding protein compare
MMP_RS01540 +0.2 1.0 DUF504 domain-containing protein compare
MMP_RS06745 +0.2 1.4 DUF2119 domain-containing protein compare
MMP_RS05285 +0.2 1.3 MMPL family transporter compare
MMP_RS04785 +0.2 1.8 hypothetical protein compare
MMP_RS05695 +0.2 1.6 phospholipase D-like domain-containing protein compare
MMP_RS03520 +0.2 0.7 YwbE family protein compare
MMP_RS03895 +0.2 1.1 hypothetical protein compare
MMP_RS05640 +0.2 1.3 UTP--glucose-1-phosphate uridylyltransferase GalU compare
MMP_RS00325 +0.2 0.6 RNA-binding protein compare
MMP_RS01110 +0.2 1.3 FmdE family protein compare
MMP_RS02895 +0.2 1.3 DHH family phosphoesterase compare
MMP_RS05660 +0.2 1.3 phosphate ABC transporter substrate-binding protein compare
MMP_RS01320 +0.2 1.0 hypothetical protein compare
MMP_RS06560 +0.2 1.6 hypothetical protein compare
MMP_RS01785 +0.2 1.5 hypothetical protein compare
MMP_RS06570 +0.2 1.1 DUF190 domain-containing protein compare
MMP_RS02725 +0.2 1.4 molybdate ABC transporter permease subunit compare
MMP_RS05995 +0.2 1.3 FprA family A-type flavoprotein compare
MMP_RS07330 +0.2 1.7 membrane protein compare
MMP_RS06490 +0.2 1.3 hypothetical protein compare
MMP_RS02770 +0.2 1.2 hypothetical protein compare
MMP_RS03225 +0.2 1.2 acetolactate decarboxylase compare
MMP_RS00185 +0.2 1.5 potassium channel protein compare
MMP_RS06520 +0.2 1.2 DUF1786 domain-containing protein compare
MMP_RS08855 +0.2 1.2 hypothetical protein compare
MMP_RS02480 +0.2 0.7 hypothetical protein compare
MMP_RS02815 +0.2 0.8 hypothetical protein compare
MMP_RS00130 +0.2 0.4 nickel-responsive transcriptional regulator NikR compare
MMP_RS03585 +0.2 0.7 Hsp20/alpha crystallin family protein compare
MMP_RS00940 +0.2 1.3 daunorubicin resistance protein DrrA family ABC transporter ATP-binding protein compare
MMP_RS02690 +0.2 1.1 FmdE family protein compare
MMP_RS01960 +0.2 0.2 hypothetical protein compare
MMP_RS08555 +0.2 0.6 hypothetical protein compare
MMP_RS01185 +0.2 1.2 hypothetical protein compare
MMP_RS06155 +0.2 0.7 DUF4186 domain-containing protein compare
MMP_RS03215 +0.2 1.4 MBL fold metallo-hydrolase compare
MMP_RS07725 +0.2 0.9 4Fe-4S dicluster domain-containing protein compare
MMP_RS01630 +0.2 1.2 N-glycosylase/DNA lyase compare
MMP_RS02720 +0.2 0.9 molybdate ABC transporter substrate-binding protein compare
MMP_RS03790 +0.2 1.4 hypothetical protein compare
MMP_RS00385 +0.2 1.3 P-II family nitrogen regulator compare
MMP_RS01450 +0.2 1.3 tRNA pseudouridine(38-40) synthase TruA compare
MMP_RS06575 +0.2 1.1 fluoride efflux transporter CrcB compare
MMP_RS02225 +0.2 1.0 carbohydrate kinase family protein compare
MMP_RS03405 +0.2 1.0 RNA 3'-terminal phosphate cyclase compare
MMP_RS07800 +0.2 1.2 ATP-binding cassette domain-containing protein compare
MMP_RS04035 +0.2 0.6 hypothetical protein compare
MMP_RS00710 +0.2 0.9 hypothetical protein compare
MMP_RS00795 +0.2 1.2 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS09050 +0.2 1.0 CAP domain-containing protein compare
MMP_RS03535 +0.2 0.9 helix-turn-helix transcriptional regulator compare
MMP_RS08990 +0.2 0.7 hypothetical protein compare
MMP_RS00930 +0.2 0.9 ABC transporter permease compare
MMP_RS04105 +0.2 0.7 MarR family transcriptional regulator compare
MMP_RS06325 +0.1 0.5 hypothetical protein compare
MMP_RS01580 +0.1 1.2 PQQ-binding-like beta-propeller repeat protein compare
MMP_RS02510 +0.1 1.2 site-specific integrase compare
MMP_RS04205 +0.1 0.9 carboxymuconolactone decarboxylase family protein compare
MMP_RS02645 +0.1 1.0 ArsR family transcriptional regulator compare
MMP_RS07145 +0.1 1.1 AmmeMemoRadiSam system protein B compare
MMP_RS05980 +0.1 1.0 ferritin compare
MMP_RS02375 +0.1 1.2 hypothetical protein compare
MMP_RS03615 +0.1 1.1 4Fe-4S binding protein compare
MMP_RS02960 +0.1 1.2 class I SAM-dependent methyltransferase family protein compare
MMP_RS08700 +0.1 1.1 hypothetical protein compare
MMP_RS07095 +0.1 0.4 PspC domain-containing protein compare
MMP_RS06550 +0.1 0.9 AMP-binding protein compare
MMP_RS06875 +0.1 1.1 FAD-dependent oxidoreductase compare
MMP_RS08850 +0.1 1.3 hypothetical protein compare
MMP_RS05940 +0.1 1.1 corrinoid protein compare
MMP_RS05960 +0.1 1.3 CoB--CoM heterodisulfide reductase subunit B compare
MMP_RS07805 +0.1 0.9 ABC transporter permease compare
MMP_RS05175 +0.1 0.9 hypothetical protein compare
MMP_RS06000 +0.1 0.8 divalent-cation tolerance protein CutA compare
MMP_RS07840 +0.1 0.7 ribonuclease III compare
MMP_RS02915 +0.1 0.7 amino acid ABC transporter permease compare
MMP_RS05235 +0.1 1.1 exodeoxyribonuclease III compare
MMP_RS04280 +0.1 0.9 coenzyme F420-non-reducing hydrogenase subunit gamma compare
MMP_RS03910 +0.1 0.5 hypothetical protein compare
MMP_RS08835 +0.1 1.1 H(2)-dependent methylenetetrahydromethanopterin dehydrogenase-related protein compare
MMP_RS03890 +0.1 0.9 DUF2540 domain-containing protein compare
MMP_RS01270 +0.1 1.2 prepilin peptidase compare
MMP_RS05415 +0.1 0.6 DUF22 domain-containing protein compare
MMP_RS03840 +0.1 0.9 hypothetical protein compare
MMP_RS01515 +0.1 1.0 PINc/VapC family ATPase compare
MMP_RS02955 +0.1 0.9 DJ-1/PfpI family protein compare
MMP_RS06300 +0.1 1.0 ABC transporter substrate-binding protein compare
MMP_RS05905 +0.1 0.8 undecaprenyl-diphosphate phosphatase compare
MMP_RS01440 +0.1 1.0 NAAT family transporter compare
MMP_RS00800 +0.1 1.1 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS00645 +0.1 1.1 iron ABC transporter permease compare
MMP_RS04340 +0.1 1.1 uroporphyrinogen decarboxylase compare
MMP_RS00660 +0.1 1.1 alkaline phosphatase family protein compare
MMP_RS08275 +0.1 1.1 hypothetical protein compare
MMP_RS04020 +0.1 0.8 hypothetical protein compare
MMP_RS04050 +0.1 0.5 hypothetical protein compare
MMP_RS06675 +0.1 1.1 ADP-specific phosphofructokinase compare
MMP_RS06375 +0.1 0.9 ATP-dependent sacrificial sulfur transferase LarE compare
MMP_RS08845 +0.1 0.9 archaellum operon transcriptional activator EarA family protein compare
MMP_RS01435 +0.1 0.6 DMT family transporter compare
MMP_RS00690 +0.1 0.9 MBL fold metallo-hydrolase compare
MMP_RS05275 +0.1 1.0 AI-2E family transporter compare
MMP_RS06395 +0.1 0.5 ThiF family adenylyltransferase compare
MMP_RS02700 +0.1 0.8 formylmethanofuran dehydrogenase subunit C compare
MMP_RS06465 +0.1 1.1 NERD domain-containing protein compare
MMP_RS05550 +0.1 0.2 cation:proton antiporter compare
MMP_RS01685 +0.1 0.7 indolepyruvate oxidoreductase subunit beta compare
MMP_RS07590 +0.1 1.0 hypothetical protein compare
MMP_RS08280 +0.1 0.6 proteasome assembly chaperone family protein compare
MMP_RS06115 +0.1 1.0 class II aldolase/adducin family protein compare
MMP_RS01315 +0.1 1.1 DUF2341 domain-containing protein compare
MMP_RS02545 +0.1 0.6 hypothetical protein compare
MMP_RS01300 +0.1 1.0 hypothetical protein compare
MMP_RS07640 +0.1 0.9 mechanosensitive ion channel family protein compare
MMP_RS08175 +0.1 0.9 7-cyano-7-deazaguanine synthase compare
MMP_RS05900 +0.1 0.9 tetratricopeptide repeat protein compare
MMP_RS08155 +0.1 0.8 hypothetical protein compare
MMP_RS02565 +0.1 0.9 hypothetical protein compare
MMP_RS02290 +0.1 0.8 MBL fold metallo-hydrolase compare
MMP_RS03395 +0.1 0.8 hypothetical protein compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments

For stress Nalidixic acid sodium salt across organisms