Experiment set5IT089 for Pseudomonas fluorescens FW300-N2E2

Compare to:

LB with Nickel (II) chloride hexahydrate 0.0025 M

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_5237 -4.7 -3.2 Hypoxanthine-guanine phosphoribosyltransferase (EC 2.4.2.8) compare
Pf6N2E2_5027 -4.6 -10.3 AMP nucleosidase (EC 3.2.2.4) compare
Pf6N2E2_5679 -4.6 -4.5 hypothetical protein compare
Pf6N2E2_3948 -4.3 -10.3 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) compare
Pf6N2E2_3782 -4.2 -2.9 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_4206 -4.1 -2.8 Chromosome (plasmid) partitioning protein ParB compare
Pf6N2E2_2127 -4.1 -4.0 Transcriptional regulator, GntR family domain / Aspartate aminotransferase (EC 2.6.1.1) compare
Pf6N2E2_2258 -4.1 -7.3 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_4071 -3.9 -4.7 Phosphate transport system regulatory protein PhoU compare
Pf6N2E2_5430 -3.9 -6.9 Transglycosylase, Slt family compare
Pf6N2E2_5014 -3.8 -1.8 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_2447 -3.7 -6.2 Probable protease htpX homolog (EC 3.4.24.-) compare
Pf6N2E2_4453 -3.5 -16.0 Polyphosphate kinase (EC 2.7.4.1) compare
Pf6N2E2_3941 -3.4 -2.4 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
Pf6N2E2_37 -3.4 -4.0 6-carboxytetrahydropterin synthase (EC 4.1.2.50) @ Queuosine biosynthesis QueD, PTPS-I compare
Pf6N2E2_4075 -3.4 -4.0 Phosphate ABC transporter, periplasmic phosphate-binding protein PstS (TC 3.A.1.7.1) compare
Pf6N2E2_3574 -3.3 -12.3 Mannose-6-phosphate isomerase (EC 5.3.1.8) conserved
Pf6N2E2_563 -3.3 -7.6 Serine transporter compare
Pf6N2E2_2574 -3.2 -2.2 Flagellar synthesis regulator FleN compare
Pf6N2E2_4372 -3.1 -4.3 FIG00460773: hypothetical protein compare
Pf6N2E2_4999 -3.1 -6.6 Membrane-bound lytic murein transglycosylase B precursor (EC 3.2.1.-) compare
Pf6N2E2_3908 -3.1 -3.7 Glutamate--cysteine ligase (EC 6.3.2.2) compare
Pf6N2E2_4155 -3.1 -9.8 N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) compare
Pf6N2E2_4612 -3.1 -5.1 Glutathione synthetase (EC 6.3.2.3) compare
Pf6N2E2_6140 -3.0 -1.4 Large Subunit Ribosomal RNA; lsuRNA; LSU rRNA compare
Pf6N2E2_3460 -2.9 -2.0 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) compare
Pf6N2E2_3505 -2.9 -1.8 Translation initiation factor SUI1-related protein compare
Pf6N2E2_3534 -2.9 -2.9 Cobalamin biosynthesis protein CobG compare
Pf6N2E2_3060 -2.9 -3.6 Outer membrane protein H precursor compare
Pf6N2E2_4611 -2.9 -2.8 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_2274 -2.8 -5.4 Soluble pyridine nucleotide transhydrogenase (EC 1.6.1.1) compare
Pf6N2E2_5006 -2.8 -6.4 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_3351 -2.8 -4.2 tRNA pseudouridine synthase B (EC 4.2.1.70) compare
Pf6N2E2_4447 -2.8 -13.2 Cytochrome c family protein conserved
Pf6N2E2_5943 -2.7 -2.6 hypothetical protein compare
Pf6N2E2_3876 -2.7 -4.1 Agmatine deiminase (EC 3.5.3.12) compare
Pf6N2E2_344 -2.7 -3.7 hypothetical protein compare
Pf6N2E2_4072 -2.7 -4.9 Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1) compare
Pf6N2E2_760 -2.7 -11.3 Na+/H+ antiporter NhaB compare
Pf6N2E2_2218 -2.7 -3.6 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_3461 -2.7 -2.5 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
Pf6N2E2_4908 -2.6 -6.0 UDP-glucose 4-epimerase (EC 5.1.3.2) compare
Pf6N2E2_3199 -2.6 -6.0 S-adenosylmethionine:tRNA ribosyltransferase-isomerase (EC 5.-.-.-) compare
Pf6N2E2_3253 -2.6 -5.7 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_3258 -2.5 -2.4 Uncharacterized ABC transporter, periplasmic component YrbD compare
Pf6N2E2_4276 -2.5 -4.5 Phosphogluconate repressor HexR, RpiR family compare
Pf6N2E2_1625 -2.5 -3.3 Ferric reductase (1.6.99.14) compare
Pf6N2E2_1545 -2.5 -4.4 N-carbamoylputrescine amidase (EC 3.5.1.53) compare
Pf6N2E2_2252 -2.5 -4.1 NreA-like protein compare
Pf6N2E2_3661 -2.5 -3.3 hypothetical protein compare
Pf6N2E2_5668 -2.4 -4.3 Succinylglutamic semialdehyde dehydrogenase (EC 1.2.1.71) compare
Pf6N2E2_6063 -2.4 -6.9 2-methylcitrate dehydratase FeS dependent (EC 4.2.1.79) compare
Pf6N2E2_2967 -2.4 -2.3 Cold shock protein CspA compare
Pf6N2E2_5671 -2.4 -3.2 Succinylglutamate desuccinylase (EC 3.5.1.96) compare
Pf6N2E2_5746 -2.3 -2.8 Cobalamin synthase compare
Pf6N2E2_2181 -2.3 -2.2 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf6N2E2_4418 -2.3 -1.1 Diaminopimelate epimerase (EC 5.1.1.7) compare
Pf6N2E2_4369 -2.3 -1.6 Exodeoxyribonuclease III (EC 3.1.11.2) compare
Pf6N2E2_3612 -2.3 -2.2 HflK protein compare
Pf6N2E2_1635 -2.3 -4.7 ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components compare
Pf6N2E2_3607 -2.3 -7.2 3'-to-5' exoribonuclease RNase R compare
Pf6N2E2_624 -2.3 -4.6 hypothetical protein PA3071 compare
Pf6N2E2_4614 -2.3 -3.4 twitching motility protein PilH compare
Pf6N2E2_634 -2.3 -8.7 NAD-specific glutamate dehydrogenase (EC 1.4.1.2), large form compare
Pf6N2E2_5342 -2.3 -3.0 21 kDa hemolysin precursor compare
Pf6N2E2_5219 -2.2 -6.9 FIG140336: TPR domain protein compare
Pf6N2E2_4476 -2.2 -3.8 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) compare
Pf6N2E2_5546 -2.2 -5.6 Queuosine Biosynthesis QueC ATPase conserved
Pf6N2E2_4067 -2.2 -6.9 Phosphate regulon sensor protein PhoR (SphS) (EC 2.7.13.3) compare
Pf6N2E2_3617 -2.2 -4.5 N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) compare
Pf6N2E2_2675 -2.1 -1.4 ATP-dependent RNA helicase SrmB compare
Pf6N2E2_5742 -2.1 -5.2 Cobyric acid synthase (EC 6.3.5.10) compare
Pf6N2E2_3611 -2.1 -1.4 HflC protein compare
Pf6N2E2_5520 -2.1 -4.8 Sensory box histidine kinase compare
Pf6N2E2_2261 -2.0 -4.8 VacJ-like lipoprotein precursor compare
Pf6N2E2_625 -2.0 -4.4 MoxR-like ATPase in aerotolerance operon compare
Pf6N2E2_1652 -2.0 -2.9 Transcriptional regulator, TetR family compare
Pf6N2E2_2277 -2.0 -1.9 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf6N2E2_3842 -2.0 -3.2 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_4797 -2.0 -1.5 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
Pf6N2E2_1935 -2.0 -2.8 Enoyl-CoA hydratase (EC 4.2.1.17) compare
Pf6N2E2_2825 -2.0 -3.3 RND efflux system, outer membrane lipoprotein CmeC compare
Pf6N2E2_3770 -2.0 -2.2 ATP-dependent hsl protease ATP-binding subunit HslU compare
Pf6N2E2_5740 -2.0 -4.2 Adenosylcobinamide-phosphate synthase (EC 6.3.1.10) compare
Pf6N2E2_1632 -2.0 -4.1 Iron(III) dicitrate transport system, periplasmic iron-binding protein FecB (TC 3.A.1.14.1) compare
Pf6N2E2_5793 -2.0 -5.8 Aspartyl aminopeptidase compare
Pf6N2E2_3610 -2.0 -3.0 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_5780 -2.0 -7.4 Periplasmic protease compare
Pf6N2E2_1660 -2.0 -2.6 RND efflux system, membrane fusion protein CmeA compare
Pf6N2E2_5527 -1.9 -1.9 Cold shock protein CspC compare
Pf6N2E2_2074 -1.9 -1.6 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_3834 -1.9 -5.9 Lipoprotein NlpD compare
Pf6N2E2_1636 -1.9 -6.7 Ferrichrome-iron receptor compare
Pf6N2E2_5178 -1.9 -2.2 CDP-diacylglycerol--serine O-phosphatidyltransferase (EC 2.7.8.8) compare
Pf6N2E2_4153 -1.9 -1.3 Sensory box histidine kinase compare
Pf6N2E2_4352 -1.9 -2.5 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
Pf6N2E2_3040 -1.9 -5.8 5-nucleotidase SurE (EC 3.1.3.5) compare
Pf6N2E2_2752 -1.9 -6.5 Exported zinc metalloprotease YfgC precursor compare
Pf6N2E2_2253 -1.9 -3.4 hypothetical protein compare
Pf6N2E2_4416 -1.9 -2.2 Tyrosine recombinase XerC compare
Pf6N2E2_4391 -1.9 -4.4 D-amino acid dehydrogenase small subunit (EC 1.4.99.1) compare
Pf6N2E2_3260 -1.9 -3.5 Uncharacterized ABC transporter, ATP-binding protein YrbF compare
Pf6N2E2_4074 -1.9 -8.8 Phosphate transport system permease protein PstC (TC 3.A.1.7.1) compare
Pf6N2E2_5242 -1.9 -2.1 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
Pf6N2E2_2714 -1.8 -1.8 transcriptional regulator, Crp/Fnr family compare
Pf6N2E2_3835 -1.8 -3.3 Carboxyl-terminal protease (EC 3.4.21.102) compare
Pf6N2E2_5544 -1.8 -4.9 TPR repeat containing exported protein; Putative periplasmic protein contains a protein prenylyltransferase domain compare
Pf6N2E2_302 -1.8 -5.3 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_4084 -1.8 -4.6 Transcriptional regulator compare
Pf6N2E2_5669 -1.8 -5.1 Succinylarginine dihydrolase (EC 3.5.3.23) compare
Pf6N2E2_4187 -1.8 -3.6 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
Pf6N2E2_3535 -1.8 -4.8 Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-) compare
Pf6N2E2_3271 -1.8 -2.0 Phosphocarrier protein, nitrogen regulation associated compare
Pf6N2E2_1116 -1.8 -1.7 Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) compare
Pf6N2E2_3720 -1.8 -2.9 FIG027190: Putative transmembrane protein compare
Pf6N2E2_4172 -1.8 -4.2 Methionine ABC transporter ATP-binding protein compare
Pf6N2E2_2217 -1.8 -3.8 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_3074 -1.8 -1.8 FIG00960973: hypothetical protein compare
Pf6N2E2_2473 -1.7 -1.4 Major outer membrane lipoprotein I compare
Pf6N2E2_5567 -1.7 -1.9 Glutamate Aspartate transport ATP-binding protein GltL (TC 3.A.1.3.4) compare
Pf6N2E2_5245 -1.7 -5.8 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_6087 -1.7 -2.8 Short-chain dehydrogenase/reductase SDR compare
Pf6N2E2_3833 -1.7 -3.4 hypothetical protein compare
Pf6N2E2_1056 -1.7 -1.0 Quinone oxidoreductase (EC 1.6.5.5) compare
Pf6N2E2_4181 -1.7 -1.1 Organic hydroperoxide resistance protein compare
Pf6N2E2_1110 -1.7 -4.0 FIG00964414: hypothetical protein compare
Pf6N2E2_1634 -1.7 -3.8 ABC-type Fe3+-siderophore transport system, permease component compare
Pf6N2E2_2514 -1.7 -4.1 regulator of length of O-antigen component of lipopolysaccharide chains compare
Pf6N2E2_2282 -1.7 -2.9 Predicted transcriptional regulator for fatty acid degradation FadQ, TetR family compare
Pf6N2E2_2126 -1.7 -3.9 4Fe-4S ferredoxin, iron-sulfur binding compare
Pf6N2E2_3252 -1.7 -5.1 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_4585 -1.7 -8.4 Cell division protein FtsX compare
Pf6N2E2_6061 -1.6 -4.9 Methylisocitrate lyase (EC 4.1.3.30) (from data) compare
Pf6N2E2_2852 -1.6 -5.6 GGDEF domain/EAL domain protein compare
Pf6N2E2_2474 -1.6 -6.4 ErfK/YbiS/YcfS/YnhG family protein compare
Pf6N2E2_1626 -1.6 -4.6 Putative ATP-binding component of a transport system compare
Pf6N2E2_2340 -1.6 -3.8 Transcriptional regulator, GntR family compare
Pf6N2E2_3844 -1.6 -2.2 hypothetical protein compare
Pf6N2E2_6064 -1.6 -3.6 2-methylaconitate isomerase compare
Pf6N2E2_469 -1.6 -1.6 lipoprotein, putative compare
Pf6N2E2_600 -1.6 -2.1 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases compare
Pf6N2E2_3839 -1.6 -2.5 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_648 -1.6 -2.0 General secretion pathway protein K compare
Pf6N2E2_5727 -1.6 -4.9 FIG00955360: hypothetical protein compare
Pf6N2E2_4918 -1.6 -2.1 Ribonucleotide reductase transcriptional regulator NrdR compare
Pf6N2E2_4615 -1.6 -1.5 type IV pili signal transduction protein PilI compare
Pf6N2E2_4173 -1.6 -3.6 Methionine ABC transporter permease protein compare
Pf6N2E2_2755 -1.6 -1.4 Sigma factor RpoE negative regulatory protein RseA compare
Pf6N2E2_2788 -1.5 -2.4 Transcriptional regulator, AsnC family compare
Pf6N2E2_55 -1.5 -2.2 Probable hydrolase compare
Pf6N2E2_3533 -1.5 -2.3 Cobalt-precorrin-8x methylmutase (EC 5.4.1.2) compare
Pf6N2E2_443 -1.5 -2.2 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_1633 -1.5 -2.4 Iron(III) dicitrate transport system permease protein FecD (TC 3.A.1.14.1) compare
Pf6N2E2_2499 -1.5 -2.2 Competence protein ComEA helix-hairpin-helix region precursor compare
Pf6N2E2_5711 -1.5 -4.5 tRNA(Cytosine32)-2-thiocytidine synthetase compare
Pf6N2E2_2189 -1.5 -3.0 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) compare
Pf6N2E2_3847 -1.5 -2.8 FIG001341: Probable Fe(2+)-trafficking protein YggX compare
Pf6N2E2_5331 -1.4 -4.9 ATPase, AFG1 family compare
Pf6N2E2_5160 -1.4 -1.1 C4-type zinc finger protein, DksA/TraR family compare
Pf6N2E2_3783 -1.4 -2.7 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_5111 -1.4 -2.3 FKBP-type peptidyl-prolyl cis-trans isomerase SlpA (EC 5.2.1.8) compare
Pf6N2E2_4120 -1.4 -6.8 Trk system potassium uptake protein TrkA compare
Pf6N2E2_2477 -1.4 -1.6 ABC transporter ATP-binding protein YvcR compare
Pf6N2E2_2344 -1.4 -5.6 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) compare
Pf6N2E2_2138 -1.4 -3.2 Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) compare
Pf6N2E2_178 -1.4 -1.1 Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) compare
Pf6N2E2_339 -1.4 -2.3 Glutathione-regulated potassium-efflux system protein KefC compare
Pf6N2E2_3920 -1.4 -7.1 Cystine ABC transporter, permease protein compare
Pf6N2E2_2064 -1.4 -2.6 Cobalt-precorrin-3b C17-methyltransferase compare
Pf6N2E2_5987 -1.4 -3.6 OmpA family protein compare
Pf6N2E2_3251 -1.4 -5.5 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_2264 -1.4 -2.4 NADPH dependent preQ0 reductase (EC 1.7.1.13) compare
Pf6N2E2_5155 -1.4 -2.2 Poly(A) polymerase (EC 2.7.7.19) compare
Pf6N2E2_3666 -1.4 -2.7 InaA protein compare
Pf6N2E2_5573 -1.4 -3.2 Glycerol-3-phosphate regulon repressor, DeoR family compare
Pf6N2E2_622 -1.4 -2.5 BatA (Bacteroides aerotolerance operon) compare
Pf6N2E2_1932 -1.3 -3.7 Transcriptional regulator, IclR family compare
Pf6N2E2_620 -1.3 -5.1 BatD compare
Pf6N2E2_2388 -1.3 -3.2 Esterase/lipase/thioesterase family protein compare
Pf6N2E2_1431 -1.3 -1.8 Branched-chain amino acid transport system permease protein LivM (TC 3.A.1.4.1) compare
Pf6N2E2_961 -1.3 -1.6 FIG00954712: hypothetical protein compare
Pf6N2E2_5494 -1.3 -3.2 Pyruvate kinase (EC 2.7.1.40) compare
Pf6N2E2_4417 -1.3 -2.4 Protein of unknown function DUF484 compare
Pf6N2E2_3524 -1.3 -2.8 hypothetical protein compare
Pf6N2E2_3226 -1.3 -2.3 Predicted D-glucarate or D-galactorate regulator, GntR family compare
Pf6N2E2_5068 -1.3 -6.2 putative Cytochrome bd2, subunit I compare
Pf6N2E2_42 -1.3 -3.6 Sensor protein PhoQ (EC 2.7.13.3) compare
Pf6N2E2_525 -1.3 -3.7 C4-type zinc finger protein, DksA/TraR family compare
Pf6N2E2_5738 -1.3 -4.4 Cobyrinic acid A,C-diamide synthase compare
Pf6N2E2_4451 -1.3 -3.2 FIG139438: lipoprotein B compare
Pf6N2E2_4584 -1.3 -1.5 Cell division transporter, ATP-binding protein FtsE (TC 3.A.5.1.1) compare
Pf6N2E2_3134 -1.3 -0.8 hypothetical protein compare
Pf6N2E2_2073 -1.3 -4.8 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_895 -1.3 -3.4 Transcriptional regulator, HxlR family compare
Pf6N2E2_4423 -1.3 -1.4 FIG00953342: hypothetical protein compare
Pf6N2E2_1087 -1.3 -4.8 Iron siderophore sensor protein compare
Pf6N2E2_3546 -1.3 -2.5 ABC transporter (iron.B12.siderophore.hemin) , permease component compare
Pf6N2E2_5986 -1.3 -2.1 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_1312 -1.3 -1.5 4-hydroxyphenylacetate symporter, major facilitator superfamily (MFS) compare
Pf6N2E2_2746 -1.3 -3.5 Outer membrane protein NlpB, lipoprotein component of the protein assembly complex (forms a complex with YaeT, YfiO, and YfgL); Lipoprotein-34 precursor compare


Specific Phenotypes

For 16 genes in this experiment

For stress Nickel (II) chloride hexahydrate in Pseudomonas fluorescens FW300-N2E2

For stress Nickel (II) chloride hexahydrate across organisms