Experiment set5IT086 for Pseudomonas fluorescens FW300-N2E2

Compare to:

LB with dimethyl sulfone 0.25 M

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_4584 -5.2 -3.6 Cell division transporter, ATP-binding protein FtsE (TC 3.A.5.1.1) compare
Pf6N2E2_5069 -4.6 -6.2 putative Cytochrome bd2, subunit II compare
Pf6N2E2_5342 -4.2 -2.9 21 kDa hemolysin precursor compare
Pf6N2E2_5150 -4.2 -4.0 Glucose-6-phosphate isomerase (EC 5.3.1.9) compare
Pf6N2E2_156 -4.0 -2.7 Carbon storage regulator compare
Pf6N2E2_5014 -4.0 -1.8 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_2201 -3.8 -3.7 Transmembrane regulator protein PrtR compare
Pf6N2E2_5807 -3.8 -5.2 5-Hydroxyisourate Hydrolase (HIUase) (EC 3.5.2.17) compare
Pf6N2E2_3658 -3.7 -5.6 Lipid A core - O-antigen ligase and related enzymes compare
Pf6N2E2_2219 -3.6 -2.5 Cell division trigger factor (EC 5.2.1.8) compare
Pf6N2E2_3941 -3.6 -2.5 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
Pf6N2E2_2506 -3.6 -13.0 nucleotide sugar epimerase/dehydratase WbpM compare
Pf6N2E2_2938 -3.5 -4.8 Outer membrane lipoprotein compare
Pf6N2E2_2752 -3.5 -7.2 Exported zinc metalloprotease YfgC precursor compare
Pf6N2E2_3617 -3.5 -5.3 N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) compare
Pf6N2E2_3521 -3.5 -9.7 Sensor histidine kinase/response regulator compare
Pf6N2E2_2574 -3.4 -2.3 Flagellar synthesis regulator FleN compare
Pf6N2E2_5132 -3.3 -9.8 NADH dehydrogenase (EC 1.6.99.3) compare
Pf6N2E2_2510 -3.2 -3.8 Lipid carrier : UDP-N-acetylgalactosaminyltransferase (EC 2.4.1.-) / Alpha-1,3-N-acetylgalactosamine transferase PglA (EC 2.4.1.-); Putative glycosyltransferase compare
Pf6N2E2_3134 -3.2 -1.4 hypothetical protein compare
Pf6N2E2_2344 -3.2 -10.0 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) compare
Pf6N2E2_5006 -3.1 -7.2 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_4803 -3.1 -2.1 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
Pf6N2E2_5321 -3.1 -9.1 Heme O synthase, protoheme IX farnesyltransferase (EC 2.5.1.-) COX10-CtaB compare
Pf6N2E2_2274 -3.1 -5.1 Soluble pyridine nucleotide transhydrogenase (EC 1.6.1.1) compare
Pf6N2E2_2754 -3.1 -4.5 Sigma factor RpoE negative regulatory protein RseB precursor compare
Pf6N2E2_5245 -3.0 -6.2 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_3461 -3.0 -2.9 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
Pf6N2E2_3665 -3.0 -1.3 serine/threonine protein kinase compare
Pf6N2E2_5647 -3.0 -5.3 Transcriptional regulator, TetR family compare
Pf6N2E2_4072 -3.0 -5.3 Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1) compare
Pf6N2E2_160 -2.9 -2.4 hypothetical protein compare
Pf6N2E2_4585 -2.9 -11.8 Cell division protein FtsX compare
Pf6N2E2_3534 -2.9 -3.6 Cobalamin biosynthesis protein CobG compare
Pf6N2E2_4204 -2.8 -1.9 rRNA small subunit 7-methylguanosine (m7G) methyltransferase GidB compare
Pf6N2E2_5544 -2.8 -7.6 TPR repeat containing exported protein; Putative periplasmic protein contains a protein prenylyltransferase domain compare
Pf6N2E2_5172 -2.8 -3.3 FOG: TPR repeat compare
Pf6N2E2_5068 -2.7 -10.5 putative Cytochrome bd2, subunit I compare
Pf6N2E2_2447 -2.7 -7.9 Probable protease htpX homolog (EC 3.4.24.-) compare
Pf6N2E2_5242 -2.7 -2.6 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
Pf6N2E2_2507 -2.6 -5.8 Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase (EC 2.7.8.-) compare
Pf6N2E2_6082 -2.6 -4.3 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_4454 -2.6 -5.5 Exopolyphosphatase (EC 3.6.1.11) compare
Pf6N2E2_3661 -2.6 -3.5 hypothetical protein compare
Pf6N2E2_5733 -2.6 -4.9 NLP/P60 family protein compare
Pf6N2E2_3908 -2.6 -5.4 Glutamate--cysteine ligase (EC 6.3.2.2) compare
Pf6N2E2_4369 -2.5 -1.7 Exodeoxyribonuclease III (EC 3.1.11.2) compare
Pf6N2E2_5178 -2.5 -2.4 CDP-diacylglycerol--serine O-phosphatidyltransferase (EC 2.7.8.8) compare
Pf6N2E2_4451 -2.5 -5.9 FIG139438: lipoprotein B compare
Pf6N2E2_445 -2.5 -5.2 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) compare
Pf6N2E2_5319 -2.5 -5.9 Cytochrome O ubiquinol oxidase subunit III (EC 1.10.3.-) compare
Pf6N2E2_2513 -2.4 -4.7 UDP-glucose dehydrogenase (EC 1.1.1.22) compare
Pf6N2E2_5155 -2.4 -3.2 Poly(A) polymerase (EC 2.7.7.19) compare
Pf6N2E2_3834 -2.4 -6.5 Lipoprotein NlpD compare
Pf6N2E2_5677 -2.4 -1.4 Carbon storage regulator compare
Pf6N2E2_4614 -2.3 -3.9 twitching motility protein PilH compare
Pf6N2E2_5318 -2.3 -13.4 Cytochrome O ubiquinol oxidase subunit I (EC 1.10.3.-) compare
Pf6N2E2_5740 -2.3 -5.3 Adenosylcobinamide-phosphate synthase (EC 6.3.1.10) compare
Pf6N2E2_5555 -2.3 -1.4 Cold shock protein CspA compare
Pf6N2E2_4999 -2.3 -6.0 Membrane-bound lytic murein transglycosylase B precursor (EC 3.2.1.-) compare
Pf6N2E2_3252 -2.3 -6.3 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_2822 -2.3 -6.8 Transcription repressor of multidrug efflux pump acrAB operon, TetR (AcrR) family compare
Pf6N2E2_2586 -2.3 -1.7 Hpt domain protein compare
Pf6N2E2_2487 -2.3 -1.4 FIG00956090: hypothetical protein compare
Pf6N2E2_5320 -2.3 -6.6 Cytochrome O ubiquinol oxidase subunit IV (EC 1.10.3.-) compare
Pf6N2E2_5494 -2.2 -5.1 Pyruvate kinase (EC 2.7.1.40) compare
Pf6N2E2_2088 -2.2 -2.2 SOS-response repressor and protease LexA (EC 3.4.21.88) compare
Pf6N2E2_3610 -2.2 -5.5 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_5520 -2.2 -6.1 Sensory box histidine kinase compare
Pf6N2E2_3258 -2.2 -3.6 Uncharacterized ABC transporter, periplasmic component YrbD compare
Pf6N2E2_1299 -2.2 -3.7 Transcriptional regulator, TetR family compare
Pf6N2E2_3839 -2.2 -4.4 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_5316 -2.2 -1.5 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf6N2E2_4601 -2.2 -2.2 Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC compare
Pf6N2E2_3659 -2.2 -5.2 Protein fixF compare
Pf6N2E2_2218 -2.2 -4.5 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_2391 -2.2 -9.6 FIG137360: hypothetical protein compare
Pf6N2E2_2261 -2.2 -5.9 VacJ-like lipoprotein precursor compare
Pf6N2E2_3842 -2.1 -3.3 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_4153 -2.1 -1.4 Sensory box histidine kinase compare
Pf6N2E2_2572 -2.1 -2.5 Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY compare
Pf6N2E2_4611 -2.1 -3.7 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_144 -2.1 -12.7 Uncharacterized protein YtfM precursor compare
Pf6N2E2_3460 -2.1 -2.0 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) compare
Pf6N2E2_2509 -2.1 -1.4 UDP-glucose 4-epimerase (EC 5.1.3.2) compare
Pf6N2E2_4047 -2.1 -5.3 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_4764 -2.1 -4.6 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf6N2E2_1110 -2.1 -2.8 FIG00964414: hypothetical protein compare
Pf6N2E2_4160 -2.0 -1.3 Cytochrome c5 compare
Pf6N2E2_2674 -2.0 -1.5 FIG00953856: hypothetical protein compare
Pf6N2E2_3253 -2.0 -5.6 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_3607 -2.0 -7.9 3'-to-5' exoribonuclease RNase R compare
Pf6N2E2_2514 -2.0 -4.4 regulator of length of O-antigen component of lipopolysaccharide chains compare
Pf6N2E2_3847 -2.0 -3.7 FIG001341: Probable Fe(2+)-trafficking protein YggX compare
Pf6N2E2_2384 -2.0 -3.9 CmpX compare
Pf6N2E2_5133 -1.9 -1.9 FIG00953980: hypothetical protein compare
Pf6N2E2_3260 -1.9 -4.1 Uncharacterized ABC transporter, ATP-binding protein YrbF compare
Pf6N2E2_5007 -1.9 -7.1 Membrane-bound lytic murein transglycosylase B precursor (EC 3.2.1.-) compare
Pf6N2E2_6063 -1.9 -6.5 2-methylcitrate dehydratase FeS dependent (EC 4.2.1.79) compare
Pf6N2E2_2065 -1.9 -3.0 Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) compare
Pf6N2E2_3270 -1.9 -3.5 Hypothetical ATP-binding protein UPF0042, contains P-loop compare
Pf6N2E2_2825 -1.9 -3.5 RND efflux system, outer membrane lipoprotein CmeC compare
Pf6N2E2_5742 -1.8 -5.2 Cobyric acid synthase (EC 6.3.5.10) compare
Pf6N2E2_4889 -1.8 -4.9 Putative transport protein compare
Pf6N2E2_1056 -1.8 -1.0 Quinone oxidoreductase (EC 1.6.5.5) compare
Pf6N2E2_43 -1.8 -5.2 Histidine permease YuiF compare
Pf6N2E2_2459 -1.8 -2.9 Organic hydroperoxide resistance protein compare
Pf6N2E2_3475 -1.8 -1.8 hypothetical protein compare
Pf6N2E2_3257 -1.8 -2.9 Uncharacterized ABC transporter, auxiliary component YrbC compare
Pf6N2E2_3783 -1.8 -4.3 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_3535 -1.8 -4.4 Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-) compare
Pf6N2E2_1404 -1.8 -3.2 Nitrous oxide reductase maturation transmembrane protein NosY compare
Pf6N2E2_133 -1.8 -2.1 hypothetical protein compare
Pf6N2E2_5944 -1.7 -4.8 Ribosomal large subunit pseudouridine synthase C (EC 4.2.1.70) compare
Pf6N2E2_1243 -1.7 -6.5 FIG00953437: hypothetical protein compare
Pf6N2E2_1078 -1.7 -7.3 Glycogen synthase, ADP-glucose transglucosylase (EC 2.4.1.21) compare
Pf6N2E2_5743 -1.7 -5.1 Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) compare
Pf6N2E2_3940 -1.7 -6.1 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_178 -1.7 -1.3 Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) compare
Pf6N2E2_3271 -1.7 -2.2 Phosphocarrier protein, nitrogen regulation associated compare
Pf6N2E2_4155 -1.7 -6.2 N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) compare
Pf6N2E2_1984 -1.7 -2.9 probable exported protein STY4558 compare
Pf6N2E2_2320 -1.7 -2.4 Heavy-metal-associated domain (N-terminus) and membrane-bounded cytochrome biogenesis cycZ-like domain, possible membrane copper tolerance protein compare
Pf6N2E2_4969 -1.6 -1.2 hypothetical protein compare
Pf6N2E2_5317 -1.6 -8.4 Cytochrome O ubiquinol oxidase subunit II (EC 1.10.3.-) compare
Pf6N2E2_4907 -1.6 -6.4 dTDP-4-dehydrorhamnose reductase (EC 1.1.1.133) compare
Pf6N2E2_290 -1.6 -3.1 Cold shock protein CspD compare
Pf6N2E2_4706 -1.6 -2.0 Electron transfer flavoprotein, beta subunit compare
Pf6N2E2_3791 -1.6 -6.7 Glucans biosynthesis glucosyltransferase H (EC 2.4.1.-) compare
Pf6N2E2_2127 -1.6 -3.6 Transcriptional regulator, GntR family domain / Aspartate aminotransferase (EC 2.6.1.1) compare
Pf6N2E2_3251 -1.6 -7.5 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_828 -1.6 -3.8 Transcriptional regulator, TetR family compare
Pf6N2E2_3782 -1.6 -2.5 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_420 -1.6 -1.5 Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY compare
Pf6N2E2_5001 -1.6 -1.5 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) compare
Pf6N2E2_5523 -1.6 -3.2 Small-conductance mechanosensitive channel compare
Pf6N2E2_4638 -1.6 -2.7 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_3537 -1.6 -2.5 Cobalt-precorrin-6x reductase (EC 1.3.1.54) compare
Pf6N2E2_4678 -1.6 -1.2 hypothetical protein compare
Pf6N2E2_2294 -1.6 -7.6 Soluble lytic murein transglycosylase precursor (EC 3.2.1.-) compare
Pf6N2E2_5574 -1.6 -6.7 Glycerol kinase (EC 2.7.1.30) compare
Pf6N2E2_2824 -1.5 -7.2 RND efflux system, inner membrane transporter CmeB compare
Pf6N2E2_16 -1.5 -1.3 hypothetical protein compare
Pf6N2E2_4433 -1.5 -5.4 Uncharacterized protein EC-HemY, likely associated with heme metabolism based on gene clustering with hemC, hemD in Proteobacteria (unrelated to HemY-type PPO in GramPositives) compare
Pf6N2E2_1283 -1.5 -2.4 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_3969 -1.5 -1.4 Membrane-fusion protein compare
Pf6N2E2_2340 -1.5 -3.6 Transcriptional regulator, GntR family compare
Pf6N2E2_2189 -1.5 -3.6 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) compare
Pf6N2E2_3829 -1.5 -3.4 Protein export cytoplasm chaperone protein (SecB, maintains protein to be exported in unfolded state) compare
Pf6N2E2_4352 -1.5 -2.7 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
Pf6N2E2_2753 -1.5 -2.1 HtrA protease/chaperone protein compare
Pf6N2E2_6140 -1.5 -0.9 Large Subunit Ribosomal RNA; lsuRNA; LSU rRNA compare
Pf6N2E2_1298 -1.4 -2.6 Xanthine transporter,putative compare
Pf6N2E2_145 -1.4 -5.3 putative exported protein compare
Pf6N2E2_2285 -1.4 -1.2 FIG00954079: hypothetical protein compare
Pf6N2E2_5956 -1.4 -4.6 FIG004453: protein YceG like compare
Pf6N2E2_5950 -1.4 -2.6 Phosphate:acyl-ACP acyltransferase PlsX compare
Pf6N2E2_2465 -1.4 -6.1 Cys regulon transcriptional activator CysB compare
Pf6N2E2_3841 -1.4 -4.2 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_4092 -1.4 -2.2 FIG00954395: hypothetical protein compare
Pf6N2E2_1435 -1.4 -2.1 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; sulfonate monooxygenase compare
Pf6N2E2_2264 -1.4 -3.1 NADPH dependent preQ0 reductase (EC 1.7.1.13) compare
Pf6N2E2_292 -1.4 -5.4 ATP-dependent Clp protease ATP-binding subunit ClpA compare
Pf6N2E2_3243 -1.4 -8.1 FIG067310: hypothetical protein compare
Pf6N2E2_5761 -1.4 -1.1 Transcriptional regulator, TetR family compare
Pf6N2E2_2258 -1.4 -5.7 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_431 -1.4 -4.1 Molybdenum transport system permease protein ModB (TC 3.A.1.8.1) compare
Pf6N2E2_4162 -1.4 -2.4 DNA polymerase I (EC 2.7.7.7) compare
Pf6N2E2_3301 -1.4 -7.4 ABC transporter, ATP-binding protein compare
Pf6N2E2_2098 -1.3 -3.2 heme uptake regulator compare
Pf6N2E2_3285 -1.3 -2.2 Rod shape-determining protein MreD compare
Pf6N2E2_572 -1.3 -2.1 hypothetical protein compare
Pf6N2E2_5156 -1.3 -1.5 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_2117 -1.3 -7.6 1,4-alpha-glucan (glycogen) branching enzyme, GH-13-type (EC 2.4.1.18) compare
Pf6N2E2_3696 -1.3 -1.0 hypothetical protein compare
Pf6N2E2_2899 -1.3 -3.0 NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) compare
Pf6N2E2_1116 -1.3 -1.3 Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) compare
Pf6N2E2_3792 -1.3 -3.9 Glucans biosynthesis protein G precursor compare
Pf6N2E2_2010 -1.3 -1.4 hypothetical protein compare
Pf6N2E2_2278 -1.3 -8.1 Transcription-repair coupling factor compare
Pf6N2E2_2472 -1.3 -2.9 hypothetical protein compare
Pf6N2E2_2488 -1.3 -1.5 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_1632 -1.3 -3.2 Iron(III) dicitrate transport system, periplasmic iron-binding protein FecB (TC 3.A.1.14.1) compare
Pf6N2E2_4074 -1.3 -5.8 Phosphate transport system permease protein PstC (TC 3.A.1.7.1) compare
Pf6N2E2_280 -1.3 -2.9 hypothetical protein compare
Pf6N2E2_2060 -1.3 -6.2 CobN component of cobalt chelatase involved in B12 biosynthesis compare
Pf6N2E2_3282 -1.3 -1.9 FIG005080: Possible exported protein compare
Pf6N2E2_1660 -1.3 -2.5 RND efflux system, membrane fusion protein CmeA compare
Pf6N2E2_358 -1.3 -3.0 Haloacid dehalogenase, type II compare
Pf6N2E2_5820 -1.3 -2.4 FIG00957914: hypothetical protein compare
Pf6N2E2_3095 -1.2 -0.9 hypothetical protein compare
Pf6N2E2_2211 -1.2 -4.5 Hydrolase, carbon-nitrogen family compare
Pf6N2E2_2335 -1.2 -3.7 Transcriptional regulator, GntR family compare
Pf6N2E2_350 -1.2 -1.8 Gfa-like protein compare
Pf6N2E2_3003 -1.2 -1.7 Bacteriophage protein GP46 compare
Pf6N2E2_5522 -1.2 -1.9 FIG001943: hypothetical protein YajQ compare
Pf6N2E2_2389 -1.2 -5.6 Phosphoenolpyruvate synthase (EC 2.7.9.2) compare
Pf6N2E2_3833 -1.2 -2.4 hypothetical protein compare
Pf6N2E2_1838 -1.2 -2.4 6-hexanolactone hydrolase compare
Pf6N2E2_3325 -1.2 -2.1 ABC transporter, ATP-binding protein compare


Specific Phenotypes

For 18 genes in this experiment

For stress dimethyl sulfone in Pseudomonas fluorescens FW300-N2E2

For stress dimethyl sulfone across organisms