Experiment set5IT086 for Methanococcus maripaludis S2

Compare to:

Formate with sodium chlorite 1.6 mM

200 most important genes:

  gene name fitness t score description  
MMP_RS03315 -5.7 -2.5 ferrous iron transport protein A compare
MMP_RS01500 -4.8 -4.0 CBS domain-containing protein compare
MMP_RS04890 -3.8 -1.4 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS01175 -3.7 -7.7 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS08460 -3.5 -4.7 proteasome-activating nucleotidase compare
MMP_RS06700 -3.4 -18.2 hypothetical protein compare
MMP_RS06680 -3.2 -19.7 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS06400 -3.1 -2.8 4Fe-4S binding protein compare
MMP_RS06685 -3.0 -16.4 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS08300 -2.9 -2.5 metal-sulfur cluster assembly factor compare
MMP_RS02010 -2.7 -11.8 PHP domain-containing protein compare
MMP_RS01755 -2.7 -2.7 DUF2097 domain-containing protein compare
MMP_RS03600 -2.7 -4.1 triose-phosphate isomerase compare
MMP_RS01020 -2.7 -2.2 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS04710 -2.7 -3.0 hypothetical protein compare
MMP_RS02280 -2.6 -2.0 DUF211 domain-containing protein compare
MMP_RS06355 -2.6 -4.8 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS08820 -2.6 -9.4 hypothetical protein compare
MMP_RS01005 -2.5 -2.8 riboflavin synthase compare
MMP_RS06345 -2.5 -12.8 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS07635 -2.5 -9.0 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS08720 -2.4 -2.8 4Fe-4S binding protein compare
MMP_RS05515 -2.4 -12.3 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS08715 -2.4 -3.5 formylmethanofuran dehydrogenase subunit B compare
MMP_RS08745 -2.4 -8.7 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS06350 -2.3 -11.3 HesA/MoeB/ThiF family protein compare
MMP_RS06295 -2.3 -9.6 methanogenesis marker 14 protein compare
MMP_RS00300 -2.3 -1.2 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS03475 -2.3 -1.1 hypothetical protein compare
MMP_RS03015 -2.3 -11.7 GTP 3' 8-cyclase MoaA compare
MMP_RS08635 -2.2 -3.4 UbiA family prenyltransferase compare
MMP_RS07005 -2.2 -1.1 4Fe-4S binding protein compare
MMP_RS06120 -2.1 -3.4 UPF0147 family protein compare
MMP_RS01610 -2.1 -6.0 hypothetical protein compare
MMP_RS00895 -2.1 -5.2 hypothetical protein compare
MMP_RS03025 -2.1 -6.4 molybdenum cofactor guanylyltransferase compare
MMP_RS01265 -2.1 -3.0 hypothetical protein compare
MMP_RS06715 -2.0 -14.2 cache domain-containing protein compare
MMP_RS00515 -2.0 -1.8 DUF655 domain-containing protein compare
MMP_RS02800 -2.0 -7.9 nucleotidyltransferase domain-containing protein compare
MMP_RS06720 -2.0 -12.6 response regulator transcription factor compare
MMP_RS01220 -2.0 -9.1 hypothetical protein compare
MMP_RS04585 -2.0 -9.9 AIR synthase related protein compare
MMP_RS06705 -2.0 -6.9 formate/nitrite transporter family protein compare
MMP_RS02235 -2.0 -14.3 CBS domain-containing protein compare
MMP_RS03435 -2.0 -2.6 ketol-acid reductoisomerase compare
MMP_RS02355 -1.9 -4.5 30S ribosomal protein S27ae compare
MMP_RS08210 -1.9 -2.6 phosphatidylglycerophosphatase A compare
MMP_RS06710 -1.9 -4.2 selenium-binding protein compare
MMP_RS05920 -1.9 -1.3 50S ribosomal protein L37e compare
MMP_RS04780 -1.9 -4.3 ribonuclease P compare
MMP_RS02195 -1.9 -5.4 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS03445 -1.9 -1.9 methanogenesis marker 17 protein compare
MMP_RS00115 -1.9 -12.6 radical SAM protein compare
MMP_RS07845 -1.8 -5.0 LL-diaminopimelate aminotransferase compare
MMP_RS02240 -1.8 -3.0 methanogenesis marker 7 protein compare
MMP_RS07735 -1.8 -1.7 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS04500 -1.8 -13.5 adenosylmethionine--8-amino-7-oxononanoate transaminase compare
MMP_RS07575 -1.8 -6.4 RNA ligase partner protein compare
MMP_RS06925 -1.8 -2.9 ribonuclease VapC4 compare
MMP_RS05875 -1.8 -5.7 hydroxyethylthiazole kinase compare
MMP_RS07545 -1.7 -2.2 HTH domain-containing protein compare
MMP_RS01960 -1.7 -1.1 hypothetical protein compare
MMP_RS06370 -1.7 -6.6 biotin synthase BioB compare
MMP_RS09020 -1.7 -2.6 hypothetical protein compare
MMP_RS01225 -1.7 -5.8 DUF5379 domain-containing protein compare
MMP_RS00305 -1.7 -3.2 phosphoribosyl-ATP diphosphatase compare
MMP_RS06270 -1.7 -6.2 TIGR00300 family protein compare
MMP_RS00685 -1.7 -5.0 2-phospho-L-lactate guanylyltransferase compare
MMP_RS06625 -1.6 -3.1 DNA primase compare
MMP_RS05550 -1.6 -1.3 cation:proton antiporter compare
MMP_RS04775 -1.6 -4.3 adenosylhomocysteinase compare
MMP_RS07445 -1.6 -5.4 helix-turn-helix domain-containing protein compare
MMP_RS08095 -1.5 -8.2 dethiobiotin synthase compare
MMP_RS07600 -1.5 -3.3 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS03640 -1.5 -4.2 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS06230 -1.5 -2.8 helix-turn-helix domain-containing protein compare
MMP_RS05540 -1.5 -3.7 hypothetical protein compare
MMP_RS06895 -1.5 -2.6 selenocysteine-specific translation elongation factor compare
MMP_RS07195 -1.5 -9.8 M20 family metallo-hydrolase compare
MMP_RS00110 -1.5 -3.3 hypothetical protein compare
MMP_RS08435 -1.5 -2.5 Era-like GTP-binding protein compare
MMP_RS02900 -1.5 -0.9 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS02875 -1.5 -8.5 chorismate pyruvate-lyase family protein compare
MMP_RS06730 -1.5 -2.2 phosphopantothenate/pantothenate synthetase compare
MMP_RS07750 -1.4 -5.3 DUF357 domain-containing protein compare
MMP_RS03035 -1.4 -3.7 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS08790 -1.4 -2.4 translation initiation factor IF-2 subunit alpha compare
MMP_RS07385 -1.4 -2.7 protein translocase SEC61 complex subunit gamma compare
MMP_RS01180 -1.4 -1.3 XTP/dITP diphosphatase compare
MMP_RS03400 -1.4 -3.1 archease compare
MMP_RS04685 -1.4 -3.8 DUF126 domain-containing protein compare
MMP_RS08100 -1.4 -7.4 8-amino-7-oxononanoate synthase compare
MMP_RS02345 -1.4 -3.7 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS07525 -1.4 -8.3 4Fe-4S binding protein compare
MMP_RS07755 -1.4 -1.5 DUF555 domain-containing protein compare
MMP_RS06285 -1.3 -2.5 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS01325 -1.3 -2.5 dihydroneopterin aldolase family protein compare
MMP_RS01795 -1.3 -2.3 methanogenesis marker 6 protein compare
MMP_RS03155 -1.3 -6.4 precorrin-6A reductase compare
MMP_RS05430 -1.3 -4.8 TIGR00288 family NYN domain-containing protein compare
MMP_RS08105 -1.3 -5.7 6-carboxyhexanoate--CoA ligase compare
MMP_RS06340 -1.3 -6.2 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS08645 -1.3 -5.3 UPF0179 family protein compare
MMP_RS06865 -1.3 -1.6 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS07645 -1.2 -5.8 aldehyde dehydrogenase family protein compare
MMP_RS02145 -1.2 -4.8 winged helix-turn-helix transcriptional regulator compare
MMP_RS05925 -1.2 -4.2 small nuclear ribonucleoprotein compare
MMP_RS02165 -1.2 -6.2 tRNA-dihydrouridine synthase compare
MMP_RS00295 -1.1 -2.5 gamma carbonic anhydrase family protein compare
MMP_RS07630 -1.1 -1.8 ATP-binding cassette domain-containing protein compare
MMP_RS07380 -1.1 -2.1 transcription elongation factor Spt5 compare
MMP_RS06020 -1.1 -5.2 archaeoflavoprotein AfpA compare
MMP_RS01365 -1.1 -4.4 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS00320 -1.1 -2.3 class I SAM-dependent methyltransferase compare
MMP_RS08320 -1.1 -4.5 molybdopterin molybdotransferase MoeA compare
MMP_RS02190 -1.1 -2.7 sulfopyruvate decarboxylase subunit alpha compare
MMP_RS06885 -1.0 -1.9 50S ribosome-binding GTPase compare
MMP_RS06110 -1.0 -2.9 ATP-dependent protease LonB compare
MMP_RS05815 -1.0 -1.8 NOL1/NOP2/sun family putative RNA methylase compare
MMP_RS08330 -1.0 -5.9 NADH-quinone oxidoreductase subunit H compare
MMP_RS08650 -1.0 -2.4 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS05555 -1.0 -2.0 DUF4040 domain-containing protein compare
MMP_RS06940 -1.0 -2.3 polyprenyl diphosphate synthase compare
MMP_RS06475 -1.0 -4.1 FAD-dependent oxidoreductase compare
MMP_RS01335 -1.0 -2.6 prefoldin subunit beta compare
MMP_RS03580 -1.0 -3.4 signal recognition particle-docking protein FtsY compare
MMP_RS06315 -1.0 -1.2 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS05345 -0.9 -4.2 hypothetical protein compare
MMP_RS02135 -0.9 -2.9 DUF5612 domain-containing protein compare
MMP_RS07625 -0.9 -3.4 cobalt ECF transporter T component CbiQ compare
MMP_RS05445 -0.9 -5.2 CoB--CoM heterodisulfide reductase subunit B compare
MMP_RS07200 -0.9 -4.0 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS01800 -0.9 -2.8 TIGR00303 family protein compare
MMP_RS01830 -0.9 -1.3 tRNA-Val compare
MMP_RS05545 -0.9 -3.2 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS07350 -0.9 -2.0 preprotein translocase subunit Sec61beta compare
MMP_RS01955 -0.9 -2.3 hypothetical protein compare
MMP_RS01250 -0.9 -4.6 tRNA (guanine(26)-N(2))-dimethyltransferase compare
MMP_RS03095 -0.9 -4.6 diphthine synthase compare
MMP_RS07580 -0.9 -1.6 DUF356 domain-containing protein compare
MMP_RS06105 -0.9 -5.7 hydrogenase maturation peptidase HycI compare
MMP_RS06855 -0.9 -5.7 hypothetical protein compare
MMP_RS05930 -0.9 -1.5 3-isopropylmalate dehydratase large subunit compare
MMP_RS07425 -0.9 -4.5 GTP-binding protein compare
MMP_RS01700 -0.8 -1.0 dihydroxy-acid dehydratase compare
MMP_RS02245 -0.8 -2.8 hypothetical protein compare
MMP_RS08240 -0.8 -5.4 methanogenesis marker 16 metalloprotein compare
MMP_RS03305 -0.8 -4.9 winged helix-turn-helix domain-containing protein compare
MMP_RS04870 -0.8 -2.8 TIGR02253 family HAD-type hydrolase compare
MMP_RS00120 -0.8 -3.8 LysR family transcriptional regulator compare
MMP_RS07555 -0.8 -0.8 monovalent cation/H+ antiporter subunit E compare
MMP_RS00985 -0.8 -4.7 CDC48 family AAA ATPase compare
MMP_RS01720 -0.8 -0.9 replication factor C large subunit compare
MMP_RS03555 -0.8 -5.6 transcriptional regulator compare
MMP_RS00050 -0.8 -3.9 AarF/UbiB family protein compare
MMP_RS01725 -0.8 -3.1 class I SAM-dependent methyltransferase family protein compare
MMP_RS08200 -0.8 -6.9 archaeosine synthase subunit alpha compare
MMP_RS00720 -0.8 -5.4 metal-dependent hydrolase compare
MMP_RS00315 -0.8 -4.6 Nif3-like dinuclear metal center hexameric protein compare
MMP_RS02340 -0.8 -0.8 DNA-directed RNA polymerase subunit E'' compare
MMP_RS06975 -0.8 -2.2 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS07730 -0.8 -1.7 pyruvate synthase subunit beta compare
MMP_RS02885 -0.8 -5.9 molybdopterin biosynthesis protein compare
MMP_RS08725 -0.8 -2.1 Ni/Fe hydrogenase subunit alpha compare
MMP_RS07355 -0.7 -1.0 transcription factor S compare
MMP_RS08165 -0.7 -2.1 phosphoglycerate dehydrogenase compare
MMP_RS07390 -0.7 -1.7 cell division protein FtsZ compare
MMP_RS01330 -0.7 -5.6 DHH family phosphoesterase compare
MMP_RS04615 -0.7 -2.6 PDGLE domain-containing protein compare
MMP_RS06310 -0.7 -2.0 NAD(P)/FAD-dependent oxidoreductase compare
MMP_RS08915 -0.7 -1.3 2 5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase compare
MMP_RS01665 -0.7 -1.8 DUF2111 domain-containing protein compare
MMP_RS01195 -0.7 -1.3 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS04875 -0.7 -2.9 energy-converting hydrogenase B subunit P compare
MMP_RS05765 -0.7 -3.7 M42 family metallopeptidase compare
MMP_RS07765 -0.7 -4.0 sodium:alanine symporter family protein compare
MMP_RS08000 -0.7 -5.9 methyl coenzyme M reductase-arginine methyltransferase Mmp10 compare
MMP_RS01380 -0.7 -2.9 PHP domain-containing protein compare
MMP_RS06175 -0.7 -3.0 winged helix-turn-helix transcriptional regulator compare
MMP_RS00810 -0.7 -3.6 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS00735 -0.7 -2.5 5 10-methenyltetrahydromethanopterin hydrogenase compare
MMP_RS07605 -0.7 -2.0 diadenylate cyclase compare
MMP_RS05450 -0.6 -2.7 CoB--CoM heterodisulfide reductase subunit C compare
MMP_RS05265 -0.6 -1.7 2-isopropylmalate synthase compare
MMP_RS02170 -0.6 -2.7 CBS domain-containing protein compare
MMP_RS04305 -0.6 -1.8 hypothetical protein compare
MMP_RS07700 -0.6 -3.4 DUF1188 domain-containing protein compare
MMP_RS03470 -0.6 -3.6 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS04850 -0.6 -5.0 UPF0254 family protein compare
MMP_RS00130 -0.6 -0.8 nickel-responsive transcriptional regulator NikR compare
MMP_RS01890 -0.6 -2.2 nucleotide sugar dehydrogenase compare
MMP_RS03700 -0.6 -3.6 sodium:proton antiporter compare
MMP_RS01445 -0.6 -3.4 hypothetical protein compare
MMP_RS00695 -0.6 -0.8 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS01385 -0.6 -0.5 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS00900 -0.6 -1.5 50S ribosomal protein L39e compare
MMP_RS05425 -0.6 -2.5 monovalent cation/H+ antiporter complex subunit F compare
MMP_RS06395 -0.6 -2.0 ThiF family adenylyltransferase compare
MMP_RS06630 -0.6 -0.5 UPF0058 family protein compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments

For stress Sodium Chlorite across organisms