Experiment set5IT078 for Methanococcus maripaludis S2

Compare to:

Formate with Lithium chloride 250 mM

200 most important genes:

  gene name fitness t score description  
MMP_RS06685 -3.6 -18.6 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS06680 -3.4 -21.0 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS03315 -3.4 -2.9 ferrous iron transport protein A compare
MMP_RS01175 -3.2 -8.4 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS01225 -3.1 -5.3 DUF5379 domain-containing protein compare
MMP_RS05555 -3.1 -3.5 DUF4040 domain-containing protein compare
MMP_RS01020 -3.0 -2.3 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS06715 -3.0 -20.7 cache domain-containing protein compare
MMP_RS07735 -3.0 -2.0 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS06345 -3.0 -19.1 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS06720 -2.9 -10.4 response regulator transcription factor compare
MMP_RS05515 -2.9 -12.5 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS00515 -2.8 -1.9 DUF655 domain-containing protein compare
MMP_RS02010 -2.7 -11.9 PHP domain-containing protein compare
MMP_RS07635 -2.7 -9.6 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS06350 -2.7 -10.4 HesA/MoeB/ThiF family protein compare
MMP_RS06700 -2.7 -16.5 hypothetical protein compare
MMP_RS08820 -2.7 -9.0 hypothetical protein compare
MMP_RS08790 -2.6 -4.5 translation initiation factor IF-2 subunit alpha compare
MMP_RS06355 -2.6 -4.3 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS07005 -2.6 -1.2 4Fe-4S binding protein compare
MMP_RS08715 -2.6 -2.6 formylmethanofuran dehydrogenase subunit B compare
MMP_RS01755 -2.6 -2.6 DUF2097 domain-containing protein compare
MMP_RS03015 -2.5 -14.6 GTP 3' 8-cyclase MoaA compare
MMP_RS01500 -2.5 -3.6 CBS domain-containing protein compare
MMP_RS01005 -2.5 -2.2 riboflavin synthase compare
MMP_RS04875 -2.5 -7.3 energy-converting hydrogenase B subunit P compare
MMP_RS08720 -2.5 -2.6 4Fe-4S binding protein compare
MMP_RS07730 -2.4 -4.2 pyruvate synthase subunit beta compare
MMP_RS07445 -2.3 -8.4 helix-turn-helix domain-containing protein compare
MMP_RS07845 -2.3 -4.8 LL-diaminopimelate aminotransferase compare
MMP_RS05925 -2.3 -7.3 small nuclear ribonucleoprotein compare
MMP_RS04585 -2.3 -11.9 AIR synthase related protein compare
MMP_RS01610 -2.3 -5.2 hypothetical protein compare
MMP_RS07350 -2.3 -2.5 preprotein translocase subunit Sec61beta compare
MMP_RS05430 -2.3 -6.0 TIGR00288 family NYN domain-containing protein compare
MMP_RS01265 -2.3 -4.2 hypothetical protein compare
MMP_RS06295 -2.3 -9.1 methanogenesis marker 14 protein compare
MMP_RS07575 -2.3 -8.4 RNA ligase partner protein compare
MMP_RS04890 -2.2 -1.3 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS05550 -2.2 -1.6 cation:proton antiporter compare
MMP_RS05875 -2.2 -7.7 hydroxyethylthiazole kinase compare
MMP_RS04870 -2.2 -6.5 TIGR02253 family HAD-type hydrolase compare
MMP_RS09020 -2.2 -2.7 hypothetical protein compare
MMP_RS06705 -2.2 -9.9 formate/nitrite transporter family protein compare
MMP_RS08745 -2.1 -8.7 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS08300 -2.0 -2.1 metal-sulfur cluster assembly factor compare
MMP_RS02195 -2.0 -6.5 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS08460 -2.0 -4.4 proteasome-activating nucleotidase compare
MMP_RS00115 -1.9 -13.6 radical SAM protein compare
MMP_RS06625 -1.9 -3.6 DNA primase compare
MMP_RS06340 -1.9 -10.0 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS03025 -1.9 -9.0 molybdenum cofactor guanylyltransferase compare
MMP_RS04685 -1.9 -5.8 DUF126 domain-containing protein compare
MMP_RS00685 -1.9 -5.9 2-phospho-L-lactate guanylyltransferase compare
MMP_RS08210 -1.8 -4.4 phosphatidylglycerophosphatase A compare
MMP_RS07380 -1.8 -4.1 transcription elongation factor Spt5 compare
MMP_RS04605 -1.8 -6.5 cobalt ECF transporter T component CbiQ compare
MMP_RS01220 -1.8 -7.4 hypothetical protein compare
MMP_RS00305 -1.8 -2.6 phosphoribosyl-ATP diphosphatase compare
MMP_RS07545 -1.8 -2.2 HTH domain-containing protein compare
MMP_RS04780 -1.8 -5.6 ribonuclease P compare
MMP_RS00695 -1.8 -1.3 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS00295 -1.7 -3.3 gamma carbonic anhydrase family protein compare
MMP_RS01380 -1.7 -4.4 PHP domain-containing protein compare
MMP_RS05540 -1.7 -3.4 hypothetical protein compare
MMP_RS07525 -1.7 -9.3 4Fe-4S binding protein compare
MMP_RS02875 -1.7 -11.2 chorismate pyruvate-lyase family protein compare
MMP_RS03960 -1.7 -1.4 hypothetical protein compare
MMP_RS06885 -1.7 -4.2 50S ribosome-binding GTPase compare
MMP_RS03435 -1.6 -2.6 ketol-acid reductoisomerase compare
MMP_RS01325 -1.6 -2.6 dihydroneopterin aldolase family protein compare
MMP_RS06020 -1.6 -4.5 archaeoflavoprotein AfpA compare
MMP_RS00750 -1.6 -3.3 fumarate hydratase compare
MMP_RS06400 -1.6 -2.4 4Fe-4S binding protein compare
MMP_RS07420 -1.6 -4.3 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS06710 -1.6 -4.5 selenium-binding protein compare
MMP_RS08645 -1.6 -7.9 UPF0179 family protein compare
MMP_RS06925 -1.5 -3.8 ribonuclease VapC4 compare
MMP_RS03580 -1.5 -4.6 signal recognition particle-docking protein FtsY compare
MMP_RS02800 -1.5 -5.0 nucleotidyltransferase domain-containing protein compare
MMP_RS04955 -1.5 -4.1 DNA topoisomerase I compare
MMP_RS02355 -1.5 -3.3 30S ribosomal protein S27ae compare
MMP_RS05245 -1.4 -9.2 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS00300 -1.4 -1.0 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS07200 -1.4 -6.1 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS06105 -1.4 -9.4 hydrogenase maturation peptidase HycI compare
MMP_RS00895 -1.4 -3.5 hypothetical protein compare
MMP_RS06730 -1.4 -3.2 phosphopantothenate/pantothenate synthetase compare
MMP_RS05930 -1.4 -3.3 3-isopropylmalate dehydratase large subunit compare
MMP_RS04090 -1.4 -2.6 hypothetical protein compare
MMP_RS06895 -1.4 -2.7 selenocysteine-specific translation elongation factor compare
MMP_RS04480 -1.4 -12.1 lysine 2 3-aminomutase compare
MMP_RS03035 -1.4 -5.0 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS04485 -1.4 -10.0 putative beta-lysine N-acetyltransferase compare
MMP_RS06865 -1.3 -1.7 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS06855 -1.3 -6.7 hypothetical protein compare
MMP_RS01800 -1.3 -4.5 TIGR00303 family protein compare
MMP_RS07755 -1.3 -1.9 DUF555 domain-containing protein compare
MMP_RS05095 -1.2 -7.0 CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon compare
MMP_RS08200 -1.2 -10.4 archaeosine synthase subunit alpha compare
MMP_RS02240 -1.2 -3.6 methanogenesis marker 7 protein compare
MMP_RS05845 -1.2 -2.0 tRNA-intron lyase compare
MMP_RS01985 -1.2 -7.4 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS06285 -1.2 -2.7 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS05060 -1.2 -8.3 AAA family ATPase compare
MMP_RS02900 -1.2 -0.8 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS02280 -1.2 -1.4 DUF211 domain-containing protein compare
MMP_RS00290 -1.2 -5.2 hypothetical protein compare
MMP_RS06120 -1.2 -2.8 UPF0147 family protein compare
MMP_RS08215 -1.1 -2.5 DUF483 domain-containing protein compare
MMP_RS00620 -1.1 -6.6 4Fe-4S binding protein compare
MMP_RS04620 -1.1 -7.5 cobalt transporter CbiM compare
MMP_RS04710 -1.1 -2.1 hypothetical protein compare
MMP_RS05080 -1.1 -7.4 acetyl-CoA decarbonylase/synthase complex subunit delta compare
MMP_RS00320 -1.1 -2.2 class I SAM-dependent methyltransferase compare
MMP_RS05100 -1.1 -9.3 CO dehydrogenase/acetyl-CoA synthase complex subunit alpha compare
MMP_RS05070 -1.1 -7.1 4Fe-4S dicluster domain-containing protein compare
MMP_RS08330 -1.1 -5.7 NADH-quinone oxidoreductase subunit H compare
MMP_RS02165 -1.1 -5.5 tRNA-dihydrouridine synthase compare
MMP_RS07630 -1.1 -1.9 ATP-binding cassette domain-containing protein compare
MMP_RS05055 -1.1 -8.2 DUF166 domain-containing protein compare
MMP_RS05425 -1.1 -5.9 monovalent cation/H+ antiporter complex subunit F compare
MMP_RS01795 -1.1 -2.1 methanogenesis marker 6 protein compare
MMP_RS05085 -1.1 -5.6 AAA family ATPase compare
MMP_RS04615 -1.1 -3.7 PDGLE domain-containing protein compare
MMP_RS07090 -1.1 -5.6 tRNA (adenine-N1)-methyltransferase compare
MMP_RS05075 -1.1 -9.0 acetyl-CoA decarbonylase/synthase complex subunit gamma compare
MMP_RS01700 -1.1 -1.1 dihydroxy-acid dehydratase compare
MMP_RS07685 -1.1 -4.3 TIGR01212 family radical SAM protein compare
MMP_RS03445 -1.1 -1.4 methanogenesis marker 17 protein compare
MMP_RS05090 -1.1 -7.1 CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta compare
MMP_RS07365 -1.1 -6.9 2-phosphoglycerate kinase compare
MMP_RS03555 -1.1 -6.7 transcriptional regulator compare
MMP_RS05265 -1.0 -2.1 2-isopropylmalate synthase compare
MMP_RS06110 -1.0 -2.9 ATP-dependent protease LonB compare
MMP_RS05765 -1.0 -5.8 M42 family metallopeptidase compare
MMP_RS05920 -1.0 -1.0 50S ribosomal protein L37e compare
MMP_RS07750 -1.0 -4.4 DUF357 domain-containing protein compare
MMP_RS00380 -1.0 -2.0 P-II family nitrogen regulator compare
MMP_RS07710 -1.0 -4.5 cell division protein FtsZ compare
MMP_RS00110 -1.0 -2.3 hypothetical protein compare
MMP_RS07820 -1.0 -4.5 UPF0104 family protein compare
MMP_RS08635 -1.0 -2.3 UbiA family prenyltransferase compare
MMP_RS06270 -0.9 -3.8 TIGR00300 family protein compare
MMP_RS05850 -0.9 -3.4 Ldh family oxidoreductase compare
MMP_RS03600 -0.9 -1.7 triose-phosphate isomerase compare
MMP_RS01195 -0.9 -1.7 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS00050 -0.9 -4.6 AarF/UbiB family protein compare
MMP_RS01365 -0.9 -2.6 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS07580 -0.9 -2.0 DUF356 domain-containing protein compare
MMP_RS05815 -0.9 -2.4 NOL1/NOP2/sun family putative RNA methylase compare
MMP_RS03095 -0.9 -5.9 diphthine synthase compare
MMP_RS01725 -0.9 -3.4 class I SAM-dependent methyltransferase family protein compare
MMP_RS08195 -0.9 -5.5 hypothetical protein compare
MMP_RS00810 -0.9 -3.6 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS06200 -0.9 -6.3 M24 family metallopeptidase compare
MMP_RS00985 -0.9 -4.7 CDC48 family AAA ATPase compare
MMP_RS01335 -0.9 -2.6 prefoldin subunit beta compare
MMP_RS04775 -0.9 -3.1 adenosylhomocysteinase compare
MMP_RS07190 -0.9 -4.6 chromosome segregation protein SMC compare
MMP_RS03640 -0.9 -3.5 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS03400 -0.9 -2.3 archease compare
MMP_RS06630 -0.8 -1.1 UPF0058 family protein compare
MMP_RS00060 -0.8 -1.3 3-dehydroquinate synthase II compare
MMP_RS07720 -0.8 -5.8 4Fe-4S binding protein compare
MMP_RS01330 -0.8 -6.2 DHH family phosphoesterase compare
MMP_RS01180 -0.8 -0.7 XTP/dITP diphosphatase compare
MMP_RS07600 -0.8 -2.4 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS00310 -0.8 -5.4 CBS domain-containing protein compare
MMP_RS01830 -0.8 -1.6 tRNA-Val compare
MMP_RS01250 -0.8 -3.6 tRNA (guanine(26)-N(2))-dimethyltransferase compare
MMP_RS05545 -0.8 -4.0 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS02345 -0.8 -2.2 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS07385 -0.8 -1.0 protein translocase SEC61 complex subunit gamma compare
MMP_RS07425 -0.8 -3.9 GTP-binding protein compare
MMP_RS06310 -0.7 -3.5 NAD(P)/FAD-dependent oxidoreductase compare
MMP_RS07790 -0.7 -5.1 segregation/condensation protein A compare
MMP_RS00555 -0.7 -4.7 MFS transporter compare
MMP_RS00520 -0.7 -1.7 RNA polymerase Rpb4 family protein compare
MMP_RS08370 -0.7 -0.6 cation:proton antiporter subunit C compare
MMP_RS07535 -0.7 -3.8 4Fe-4S binding protein compare
MMP_RS06175 -0.7 -4.9 winged helix-turn-helix transcriptional regulator compare
MMP_RS08915 -0.7 -1.5 2 5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase compare
MMP_RS01385 -0.7 -0.6 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS03475 -0.7 -0.5 hypothetical protein compare
MMP_RS05065 -0.7 -2.7 CooT family nickel-binding protein compare
MMP_RS06975 -0.7 -2.1 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS02340 -0.7 -0.9 DNA-directed RNA polymerase subunit E'' compare
MMP_RS03155 -0.7 -3.6 precorrin-6A reductase compare
MMP_RS08360 -0.7 -2.8 hypothetical protein compare
MMP_RS08240 -0.7 -4.1 methanogenesis marker 16 metalloprotein compare
MMP_RS02135 -0.7 -1.9 DUF5612 domain-containing protein compare
MMP_RS03305 -0.7 -4.1 winged helix-turn-helix domain-containing protein compare
MMP_RS08165 -0.7 -1.6 phosphoglycerate dehydrogenase compare
MMP_RS07955 -0.6 -1.8 FumA C-terminus/TtdB family hydratase beta subunit compare
MMP_RS01495 -0.6 -5.4 TraB/GumN family protein compare
MMP_RS05440 -0.6 -5.2 winged helix-turn-helix transcriptional regulator compare
MMP_RS06980 -0.6 -3.5 tRNA 2-thiocytidine biosynthesis TtcA family protein compare
MMP_RS08435 -0.6 -1.4 Era-like GTP-binding protein compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments

For stress Lithium chloride across organisms