Experiment set5IT076 for Methanococcus maripaludis S2

200 most important genes:

gene	name	fitness	t score	description
MMP_RS08300		-3.9	-3.4	metal-sulfur cluster assembly factor
MMP_RS01175		-3.6	-7.0	triphosphoribosyl-dephospho-CoA synthase
MMP_RS06700		-3.5	-22.0	hypothetical protein
MMP_RS01005		-3.5	-3.5	riboflavin synthase
MMP_RS00695		-3.3	-1.9	biotin--[acetyl-CoA-carboxylase] ligase
MMP_RS02280		-3.2	-2.5	DUF211 domain-containing protein
MMP_RS06685		-2.8	-20.9	formate dehydrogenase H subunit alpha selenocysteine-containing
MMP_RS06680		-2.8	-17.8	Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain
MMP_RS02010		-2.8	-15.9	PHP domain-containing protein
MMP_RS07845		-2.7	-4.0	LL-diaminopimelate aminotransferase
MMP_RS00300		-2.6	-1.6	6 7-dimethyl-8-ribityllumazine synthase
MMP_RS06400		-2.4	-2.4	4Fe-4S binding protein
MMP_RS08820		-2.4	-7.1	hypothetical protein
MMP_RS06345		-2.3	-15.1	formate dehydrogenase accessory sulfurtransferase FdhD
MMP_RS03015		-2.3	-14.1	GTP 3' 8-cyclase MoaA
MMP_RS05920		-2.3	-1.8	50S ribosomal protein L37e
MMP_RS02195		-2.2	-5.9	tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
MMP_RS06355		-2.2	-5.4	molybdenum cofactor biosynthesis protein MoaE
MMP_RS07635		-2.1	-8.2	MogA/MoaB family molybdenum cofactor biosynthesis protein
MMP_RS02235		-2.1	-15.6	CBS domain-containing protein
MMP_RS05515		-2.1	-9.9	cyclic pyranopterin monophosphate synthase MoaC
MMP_RS08715		-2.1	-2.8	formylmethanofuran dehydrogenase subunit B
MMP_RS01020		-2.1	-2.6	3 4-dihydroxy-2-butanone-4-phosphate synthase
MMP_RS03600		-2.1	-4.8	triose-phosphate isomerase
MMP_RS06715		-2.1	-16.6	cache domain-containing protein
MMP_RS05875		-2.1	-7.1	hydroxyethylthiazole kinase
MMP_RS04780		-2.0	-4.8	ribonuclease P
MMP_RS07380		-2.0	-3.6	transcription elongation factor Spt5
MMP_RS08720		-2.0	-2.3	4Fe-4S binding protein
MMP_RS06625		-2.0	-3.4	DNA primase
MMP_RS07575		-1.9	-7.7	RNA ligase partner protein
MMP_RS06350		-1.9	-8.8	HesA/MoeB/ThiF family protein
MMP_RS06120		-1.9	-4.1	UPF0147 family protein
MMP_RS00895		-1.9	-7.4	hypothetical protein
MMP_RS00115		-1.9	-13.4	radical SAM protein
MMP_RS08745		-1.9	-8.3	CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase
MMP_RS06295		-1.9	-8.4	methanogenesis marker 14 protein
MMP_RS07445		-1.9	-6.7	helix-turn-helix domain-containing protein
MMP_RS04775		-1.9	-3.9	adenosylhomocysteinase
MMP_RS06705		-1.9	-9.3	formate/nitrite transporter family protein
MMP_RS00305		-1.8	-4.0	phosphoribosyl-ATP diphosphatase
MMP_RS06720		-1.8	-9.9	response regulator transcription factor
MMP_RS07755		-1.8	-2.7	DUF555 domain-containing protein
MMP_RS02355		-1.7	-4.6	30S ribosomal protein S27ae
MMP_RS01500		-1.7	-4.5	CBS domain-containing protein
MMP_RS00295		-1.7	-3.8	gamma carbonic anhydrase family protein
MMP_RS06020		-1.6	-6.7	archaeoflavoprotein AfpA
MMP_RS01220		-1.6	-9.3	hypothetical protein
MMP_RS01755		-1.6	-2.7	DUF2097 domain-containing protein
MMP_RS04585		-1.6	-8.4	AIR synthase related protein
MMP_RS00515		-1.6	-2.2	DUF655 domain-containing protein
MMP_RS03400		-1.6	-4.8	archease
MMP_RS07005		-1.5	-1.1	4Fe-4S binding protein
MMP_RS04890		-1.5	-1.6	adenylyltransferase/cytidyltransferase family protein
MMP_RS04685		-1.5	-4.4	DUF126 domain-containing protein
MMP_RS06730		-1.5	-2.5	phosphopantothenate/pantothenate synthetase
MMP_RS06285		-1.5	-4.6	precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT
MMP_RS03035		-1.5	-4.2	4-hydroxy-tetrahydrodipicolinate synthase
MMP_RS08635		-1.5	-2.9	UbiA family prenyltransferase
MMP_RS06270		-1.5	-5.8	TIGR00300 family protein
MMP_RS03315		-1.4	-1.3	ferrous iron transport protein A
MMP_RS07730		-1.4	-3.6	pyruvate synthase subunit beta
MMP_RS01265		-1.4	-3.0	hypothetical protein
MMP_RS06340		-1.4	-8.5	phosphoadenosine phosphosulfate reductase family protein
MMP_RS07525		-1.4	-8.5	4Fe-4S binding protein
MMP_RS03445		-1.4	-2.0	methanogenesis marker 17 protein
MMP_RS08645		-1.4	-6.4	UPF0179 family protein
MMP_RS00685		-1.4	-6.2	2-phospho-L-lactate guanylyltransferase
MMP_RS08460		-1.4	-2.8	proteasome-activating nucleotidase
MMP_RS03025		-1.3	-6.2	molybdenum cofactor guanylyltransferase
MMP_RS02800		-1.3	-4.2	nucleotidyltransferase domain-containing protein
MMP_RS08210		-1.3	-3.6	phosphatidylglycerophosphatase A
MMP_RS07545		-1.3	-1.9	HTH domain-containing protein
MMP_RS03475		-1.3	-1.1	hypothetical protein
MMP_RS08790		-1.3	-2.8	translation initiation factor IF-2 subunit alpha
MMP_RS07580		-1.3	-3.9	DUF356 domain-containing protein
MMP_RS00110		-1.3	-4.3	hypothetical protein
MMP_RS07600		-1.3	-5.0	Ni-sirohydrochlorin a c-diamide synthase
MMP_RS01795		-1.3	-2.5	methanogenesis marker 6 protein
MMP_RS01980		-1.2	-9.8	trimeric intracellular cation channel family protein
MMP_RS00060		-1.2	-2.1	3-dehydroquinate synthase II
MMP_RS00290		-1.2	-8.2	hypothetical protein
MMP_RS07765		-1.2	-7.7	sodium:alanine symporter family protein
MMP_RS03640		-1.2	-4.6	archaeal proteasome endopeptidase complex subunit beta
MMP_RS07605		-1.2	-3.5	diadenylate cyclase
MMP_RS05555		-1.2	-2.8	DUF4040 domain-containing protein
MMP_RS02135		-1.2	-4.7	DUF5612 domain-containing protein
MMP_RS07735		-1.2	-1.4	2-ketoisovalerate ferredoxin oxidoreductase subunit alpha
MMP_RS02240		-1.2	-3.5	methanogenesis marker 7 protein
MMP_RS06230		-1.1	-3.4	helix-turn-helix domain-containing protein
MMP_RS05510		-1.1	-7.6	Rrf2 family transcriptional regulator
MMP_RS00315		-1.1	-5.6	Nif3-like dinuclear metal center hexameric protein
MMP_RS01385		-1.1	-1.1	imidazole glycerol phosphate synthase subunit HisH
MMP_RS01225		-1.1	-4.0	DUF5379 domain-containing protein
MMP_RS06925		-1.1	-2.4	ribonuclease VapC4
MMP_RS05540		-1.1	-3.7	hypothetical protein
MMP_RS01365		-1.1	-3.1	archaeal proteasome endopeptidase complex subunit alpha
MMP_RS02165		-1.1	-6.8	tRNA-dihydrouridine synthase
MMP_RS01985		-1.0	-5.6	F420-dependent methylenetetrahydromethanopterin dehydrogenase
MMP_RS05815		-1.0	-2.9	NOL1/NOP2/sun family putative RNA methylase
MMP_RS08435		-1.0	-2.7	Era-like GTP-binding protein
MMP_RS06475		-1.0	-4.7	FAD-dependent oxidoreductase
MMP_RS02900		-1.0	-0.8	imidazoleglycerol-phosphate dehydratase HisB
MMP_RS01325		-1.0	-2.6	dihydroneopterin aldolase family protein
MMP_RS03435		-1.0	-1.6	ketol-acid reductoisomerase
MMP_RS02190		-1.0	-3.2	sulfopyruvate decarboxylase subunit alpha
MMP_RS06865		-1.0	-1.7	HypC/HybG/HupF family hydrogenase formation chaperone
MMP_RS09020		-0.9	-1.5	hypothetical protein
MMP_RS01960		-0.9	-1.1	hypothetical protein
MMP_RS02875		-0.9	-5.4	chorismate pyruvate-lyase family protein
MMP_RS02340		-0.9	-1.7	DNA-directed RNA polymerase subunit E''
MMP_RS06215		-0.9	-3.3	30S ribosomal protein S6e
MMP_RS05765		-0.9	-5.2	M42 family metallopeptidase
MMP_RS06895		-0.9	-1.8	selenocysteine-specific translation elongation factor
MMP_RS02605		-0.9	-1.4	MotA/TolQ/ExbB proton channel family protein
MMP_RS01380		-0.9	-3.0	PHP domain-containing protein
MMP_RS08320		-0.9	-5.2	molybdopterin molybdotransferase MoeA
MMP_RS06105		-0.9	-5.3	hydrogenase maturation peptidase HycI
MMP_RS07750		-0.9	-3.2	DUF357 domain-containing protein
MMP_RS01610		-0.9	-2.7	hypothetical protein
MMP_RS02145		-0.9	-4.3	winged helix-turn-helix transcriptional regulator
MMP_RS08330		-0.8	-4.5	NADH-quinone oxidoreductase subunit H
MMP_RS06885		-0.8	-1.6	50S ribosome-binding GTPase
MMP_RS05345		-0.8	-4.6	hypothetical protein
MMP_RS02345		-0.8	-3.0	GTP-dependent dephospho-CoA kinase family protein
MMP_RS07200		-0.8	-4.1	[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
MMP_RS04605		-0.8	-3.2	cobalt ECF transporter T component CbiQ
MMP_RS03555		-0.8	-5.4	transcriptional regulator
MMP_RS08445		-0.8	-4.0	DUF2099 family protein
MMP_RS01250		-0.8	-4.9	tRNA (guanine(26)-N(2))-dimethyltransferase
MMP_RS00730		-0.8	-4.2	5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB
MMP_RS06940		-0.8	-2.6	polyprenyl diphosphate synthase
MMP_RS06975		-0.8	-2.0	sulfide-dependent adenosine diphosphate thiazole synthase
MMP_RS07700		-0.8	-5.1	DUF1188 domain-containing protein
MMP_RS03155		-0.8	-4.6	precorrin-6A reductase
MMP_RS02885		-0.8	-6.8	molybdopterin biosynthesis protein
MMP_RS05430		-0.8	-3.4	TIGR00288 family NYN domain-containing protein
MMP_RS05930		-0.8	-2.5	3-isopropylmalate dehydratase large subunit
MMP_RS00620		-0.8	-3.9	4Fe-4S binding protein
MMP_RS05550		-0.8	-1.0	cation:proton antiporter
MMP_RS06630		-0.7	-1.2	UPF0058 family protein
MMP_RS00050		-0.7	-3.3	AarF/UbiB family protein
MMP_RS00735		-0.7	-3.5	5 10-methenyltetrahydromethanopterin hydrogenase
MMP_RS05245		-0.7	-5.6	archaeosine biosynthesis radical SAM protein RaSEA
MMP_RS08200		-0.7	-6.2	archaeosine synthase subunit alpha
MMP_RS04850		-0.7	-6.2	UPF0254 family protein
MMP_RS07365		-0.7	-5.7	2-phosphoglycerate kinase
MMP_RS03580		-0.7	-2.5	signal recognition particle-docking protein FtsY
MMP_RS00120		-0.7	-3.4	LysR family transcriptional regulator
MMP_RS01700		-0.7	-1.1	dihydroxy-acid dehydratase
MMP_RS05445		-0.7	-4.6	CoB--CoM heterodisulfide reductase subunit B
MMP_RS00320		-0.7	-2.1	class I SAM-dependent methyltransferase
MMP_RS07695		-0.7	-4.5	DUF3236 domain-containing protein
MMP_RS00725		-0.6	-3.3	5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC
MMP_RS06200		-0.6	-4.7	M24 family metallopeptidase
MMP_RS01800		-0.6	-1.9	TIGR00303 family protein
MMP_RS01180		-0.6	-0.9	XTP/dITP diphosphatase
MMP_RS07775		-0.6	-3.6	alanine dehydrogenase
MMP_RS07425		-0.6	-3.0	GTP-binding protein
MMP_RS03095		-0.6	-4.2	diphthine synthase
MMP_RS01720		-0.6	-1.6	replication factor C large subunit
MMP_RS08725		-0.6	-2.2	Ni/Fe hydrogenase subunit alpha
MMP_RS04615		-0.6	-3.5	PDGLE domain-containing protein
MMP_RS06930		-0.6	-4.7	MBL fold metallo-hydrolase
MMP_RS04620		-0.6	-4.7	cobalt transporter CbiM
MMP_RS07535		-0.6	-4.3	4Fe-4S binding protein
MMP_RS00675		-0.6	-1.2	nitroreductase family protein
MMP_RS07790		-0.6	-4.3	segregation/condensation protein A
MMP_RS08650		-0.6	-1.5	glutamine--fructose-6-phosphate transaminase (isomerizing)
MMP_RS07385		-0.6	-1.2	protein translocase SEC61 complex subunit gamma
MMP_RS05060		-0.6	-4.8	AAA family ATPase
MMP_RS05265		-0.5	-1.4	2-isopropylmalate synthase
MMP_RS05545		-0.5	-3.0	pyridoxal phosphate-dependent aminotransferase
MMP_RS08070		-0.5	-3.4	DUF2096 domain-containing protein
MMP_RS00915		-0.5	-2.8	DUF116 domain-containing protein
MMP_RS06315		-0.5	-0.9	cobalt-precorrin-7 (C(5))-methyltransferase
MMP_RS04500		-0.5	-4.6	adenosylmethionine--8-amino-7-oxononanoate transaminase
MMP_RS02245		-0.5	-1.3	hypothetical protein
MMP_RS01240		-0.5	-0.6	7-cyano-7-deazaguanine synthase QueC
MMP_RS05845		-0.5	-0.9	tRNA-intron lyase
MMP_RS06870		-0.5	-2.3	DedA family protein
MMP_RS02130		-0.5	-1.8	zinc metalloprotease HtpX
MMP_RS05315		-0.5	-1.8	hypothetical protein
MMP_RS00720		-0.5	-3.2	metal-dependent hydrolase
MMP_RS04875		-0.5	-2.9	energy-converting hydrogenase B subunit P
MMP_RS05080		-0.5	-3.6	acetyl-CoA decarbonylase/synthase complex subunit delta
MMP_RS05800		-0.5	-3.4	B12-binding domain-containing radical SAM protein
MMP_RS07190		-0.5	-2.8	chromosome segregation protein SMC
MMP_RS07625		-0.5	-2.0	cobalt ECF transporter T component CbiQ
MMP_RS08600		-0.5	-2.2	flagellar protein D
MMP_RS05425		-0.5	-2.5	monovalent cation/H+ antiporter complex subunit F
MMP_RS08785		-0.5	-0.8	RNA-protein complex protein Nop10
MMP_RS00040		-0.5	-3.1	TIGR03576 family pyridoxal phosphate-dependent enzyme
MMP_RS03485		-0.5	-2.5	TIGR00267 family protein
MMP_RS08940		-0.5	-1.0	MetS family NSS transporter small subunit
MMP_RS05100		-0.5	-4.1	CO dehydrogenase/acetyl-CoA synthase complex subunit alpha
MMP_RS04690		-0.5	-1.1	class III signal peptide-containing protein
MMP_RS01840		-0.4	-2.9	TIGR00289 family protein
MMP_RS03305		-0.4	-3.0	winged helix-turn-helix domain-containing protein
MMP_RS05075		-0.4	-4.0	acetyl-CoA decarbonylase/synthase complex subunit gamma

Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments