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Experiment set5IT068 for
Sinorhizobium meliloti 1021
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Min media with glucose
200 most important genes:
gene
name
fitness
t score
description
SMc02766
-7.2
-8.6
tryptophan synthase subunit beta
compare
SMc02245
-7.2
-4.9
dihydroorotate dehydrogenase 2
compare
SMc00236
-7.1
-4.9
Indole-3-glycerol phosphate synthase
compare
SMc01494
-6.9
-9.5
phosphoserine phosphatase
compare
SMc02572
-6.9
-5.6
imidazole glycerol phosphate synthase subunit HisH
compare
SMc04405
-6.8
-4.7
3-isopropylmalate dehydrogenase
compare
SMc02899
-6.8
-8.1
prephenate dehydratase
compare
SMc02767
-6.6
-6.5
N-(5'-phosphoribosyl)anthranilate isomerase
compare
SM
_b21174
-6.4
-4.4
phosphate uptake ABC transporter permease
compare
SMc03823
-6.3
-7.5
isopropylmalate isomerase large subunit
compare
SMc01843
-6.2
-9.5
5,10-methylenetetrahydrofolate reductase
compare
SMc00131
-6.2
-11.2
transcriptional regulator
compare
SMc00614
-6.2
-6.0
phosphoribosylglycinamide formyltransferase
compare
SMc02574
-6.2
-4.3
imidazoleglycerol-phosphate dehydratase
compare
SMc01801
-6.1
-4.2
N-acetylglutamylphosphate reductase (EC 1.2.1.38)
(from data)
compare
SMc02725
-6.1
-9.3
anthranilate synthase
compare
SMc00235
-6.1
-8.3
anthranilate phosphoribosyltransferase
compare
SMc01726
-6.1
-5.1
acetylglutamate kinase
compare
SMc03797
-6.0
-10.1
homoserine O-succinyltransferase
compare
SMa1635
-6.0
-2.4
hypothetical protein
compare
SMc02717
-5.9
-9.0
2-isopropylmalate synthase
compare
SMc01004
-5.9
-9.0
phosphoribosyl-AMP cyclohydrolase
compare
SMc00092
-5.8
-10.5
phosphoadenosine phosphosulfate reductase
compare
SMc04028
-5.8
-13.5
glutamate synthase
compare
SMc00711
-5.7
-3.9
cyclohexadienyl dehydrogenase
compare
SMc04045
-5.7
-8.6
dihydroxy-acid dehydratase
compare
SMc03895
-5.6
-13.1
pyruvate carboxylase
compare
SMc01431
-5.6
-10.0
acetolactate synthase 3 catalytic subunit
compare
SMc00494
-5.6
-2.2
phosphoribosylformylglycinamidine synthase subunit PurS
compare
SMc00488
-5.5
-17.4
phosphoribosylformylglycinamidine synthase II
compare
SMc04005
-5.5
-6.6
pyruvate kinase
compare
SMc00615
-5.5
-9.9
phosphoribosylaminoimidazole synthetase
compare
SMc02138
-5.5
-7.4
acetylornithine transaminase
compare
SMc02765
-5.5
-12.4
tryptophan synthase subunit alpha
compare
SMc02124
-5.4
-11.0
nitrite reductase
compare
SMc02137
-5.4
-5.3
ornithine carbamoyltransferase
compare
SMc00412
-5.4
-3.7
orotidine 5'-phosphate decarboxylase
compare
SMc00918
-5.4
-9.7
ATP phosphoribosyltransferase regulatory subunit
compare
SMc03777
-5.4
-5.2
gamma-glutamyl phosphate reductase
compare
SMc02217
-5.3
-7.2
O-succinylhomoserine sulfhydrylase
compare
SMc00493
-5.3
-5.1
phosphoribosylformylglycinamidine synthase I
compare
SMc00917
-5.3
-5.1
ATP phosphoribosyltransferase (EC 2.4.2.17)
(from data)
compare
SMc00293
-5.3
-11.2
homoserine dehydrogenase
compare
SMc01054
-5.2
-5.1
required for sulfate utilization, putative electron source for sulfite reductase CysI
(from data)
compare
SMc00993
-5.2
-7.1
phosphoribosylamine--glycine ligase
compare
SMc00554
-5.1
-6.1
amidophosphoribosyltransferase
compare
SMc04002
-5.1
-7.7
phosphoribosylaminoimidazole carboxylase ATPase subunit
compare
SMc03776
-5.1
-3.5
gamma-glutamyl kinase
compare
SMc00640
-5.1
-9.7
phosphoserine aminotransferase
compare
SMc02165
-5.1
-8.4
orotate phosphoribosyltransferase
compare
SMc00091
-5.1
-10.3
sulfate adenylyltransferase
compare
SMc03981
-5.0
-4.9
phosphoglycerate kinase
compare
SMc02569
-5.0
-4.5
imidazole glycerol phosphate synthase subunit HisF
compare
SMc03112
-5.0
-15.6
B12-dependent methionine synthase
compare
SMc00495
-5.0
-5.2
phosphoribosylaminoimidazolesuccinocarboxamide synthase
compare
SM
_b21176
-4.9
-4.8
phosphate uptake ABC transporter substrate-binding protein precursor
compare
SMc02123
-4.9
-4.3
required for sulfate utilization, putative electron transport protein for sulfite reductase
(from data)
compare
SMc04026
-4.9
-8.6
glutamate synthase
compare
SM
_b21177
-4.9
-7.4
phosphate uptake ABC transporter ATP-binding protein
compare
SMc02755
-4.8
-5.7
S-adenosyl-L-homocysteine hydrolase
compare
SMc00090
-4.7
-7.8
sulfate adenylyltransferase
compare
SMc01206
-4.6
-2.6
queuine tRNA-ribosyltransferase
compare
SMc03826
-4.5
-3.1
argininosuccinate synthase
compare
SMc02307
-4.5
-6.8
histidinol dehydrogenase
compare
SMc03229
-4.4
-3.0
NAD(P)H-dependent glycerol-3-phosphate dehydrogenase
compare
SMc01360
-4.4
-4.2
aspartate carbamoyltransferase catalytic subunit
compare
SMc00294
-4.4
-12.5
aminotransferase
compare
SMc03070
-4.3
-8.3
glucose-6-phosphate 1-dehydrogenase
compare
SMc03068
-4.2
-12.0
phosphogluconate dehydratase
compare
SMc01881
-4.2
-2.9
3-methyl-2-oxobutanoate hydroxymethyltransferase
compare
SMc02707
-4.2
-4.6
hypothetical protein
compare
SMc02166
-4.1
-11.0
dihydroorotase
compare
SMc01053
-4.1
-6.8
siroheme synthase
compare
SMc04001
-4.1
-1.6
phosphoribosylaminoimidazole carboxylase catalytic subunit protein
compare
SMc00815
-4.0
-2.8
inosine 5'-monophosphate dehydrogenase
compare
SMc02570
-4.0
-4.8
1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16)
(from data)
compare
SMc04088
-4.0
-10.1
bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
compare
SMc01430
-3.9
-7.0
acetolactate synthase 3 regulatory subunit
compare
SM
_b21175
-3.9
-5.0
phosphate uptake ABC transporter permease
compare
SMc02425
-3.7
-5.7
transcriptional regulator
compare
SMc03763
-3.7
-2.5
cytosine-specific methyltransferase
compare
SMc04346
-3.7
-5.5
ketol-acid reductoisomerase
compare
SMc00876
-3.6
-7.5
ATP-binding MRP protein
compare
SMc00295
-3.5
-1.9
hypothetical protein
compare
SMc03978
-3.5
-2.4
transketolase
compare
SMc03979
-3.5
-2.3
glyceraldehyde-3-phosphate dehydrogenase
compare
SMc01569
-3.4
-1.9
carbamoyl phosphate synthase small subunit
compare
SM
_b20903
-3.4
-10.3
sugar uptake ABC transporter permease
compare
SMc03795
-3.2
-1.8
isopropylmalate isomerase small subunit
compare
SM
_b20902
-3.2
-11.9
sugar uptake ABC transporter substrate-binding protein precursor
compare
SM
_b20904
-3.2
-3.1
sugar uptake ABC transporter ATP-binding protein
compare
SMc01578
-3.2
-12.0
aspartate aminotransferase
compare
SMc02835
-3.1
-8.9
glucokinase
compare
SMc00017
-3.1
-1.7
homoserine kinase
compare
SMc02983
-3.1
-8.3
ornithine, DAP, or arginine decarboxylase
compare
SMc00982
-3.1
-7.5
dioxygenase
compare
SMc01880
-3.0
-2.1
pantoate--beta-alanine ligase
compare
SMc03924
-3.0
-11.7
glycogen synthase
compare
SMc01361
-3.0
-3.0
dihydroorotase
compare
SMc01215
-3.0
-2.1
carbamoyl phosphate synthase large subunit
compare
SMc02246
-2.9
-1.1
hypothetical protein
compare
SMc00361
-2.9
-3.8
hypothetical protein
compare
SMc01187
-2.9
-2.2
rare lipoprotein A
compare
SMc00641
-2.9
-4.8
D-3-phosphoglycerate dehydrogenase
compare
SMc01124
-2.9
-7.0
PII uridylyl-transferase
compare
SMc01568
-2.8
-2.7
hypothetical protein
compare
SMc00414
-2.8
-7.6
hypothetical protein
compare
SMc00492
-2.7
-1.5
hypothetical protein
compare
SMc01770
-2.7
-1.9
serine hydroxymethyltransferase
compare
SMc01441
-2.6
-5.1
membrane bound protease
compare
SMc02451
-2.5
-2.5
hypothetical protein
compare
SMc01440
-2.5
-4.7
hydrolase serine protease transmembrane protein
compare
SMc01028
-2.5
-14.1
phosphopyruvate hydratase
compare
SMc00838
-2.4
-6.2
hypothetical protein
compare
SMc01842
-2.3
-2.7
methyltransferase transcription regulator protein
compare
SMc00709
-2.3
-2.8
hypothetical protein
compare
SMc02102
-2.3
-5.3
hypothetical protein
compare
SMc02685
-2.3
-3.9
hypothetical protein
compare
SMc02640
-2.2
-5.5
UDP-glucuronic acid epimerase
compare
SMc02909
-2.2
-2.5
transglycosylase transmembrane protein
compare
SMc03974
-2.1
-5.1
hypothetical protein
compare
SMc02641
-2.1
-4.6
UDP-glucose 6-dehydrogenase
compare
SMc02058
-2.1
-4.0
YAJC protein
compare
SMc02115
-2.1
-1.8
hypothetical protein
compare
SMc03100
-2.0
-1.5
hypothetical protein
compare
SMc00619
-2.0
-2.4
hypothetical protein
compare
SMc02833
-2.0
-2.4
penicillin-insensitive murein endopeptidase
compare
SMc04330
-2.0
-2.4
trimethylamine methyltransferase
compare
SMc00302
-1.9
-3.5
hypothetical protein
compare
SMc01845
-1.9
-2.2
transglycosylase transmembrane protein
compare
SMc02753
-1.9
-2.1
PTS system transporter subunit IIA
compare
SMc02850
-1.9
-5.0
DNA polymerase I
compare
SMc01438
-1.8
-6.1
protease precursor signal peptide protein
compare
SMc02683
-1.8
-2.8
hypothetical protein
compare
SMc01147
-1.8
-3.7
coproporphyrinogen III oxidase
compare
SMc01208
-1.8
-3.4
peptidyl-prolyl cis-trans isomerase B protein
compare
SMc02856
-1.8
-9.8
penicillin-binding protein
compare
SMc02582
-1.7
-3.7
hypothetical protein
compare
SMa0789
-1.7
-3.1
GntR family transcriptional regulator
compare
SMc02363
-1.7
-3.7
cytochrome C-type biogenesis transmembrane protein
compare
SMc03069
-1.6
-2.7
6-phosphogluconolactonase
compare
SMc00088
-1.5
-1.8
hypothetical protein
compare
SM
_b20258
-1.5
-4.0
transcriptional regulator
compare
SMc02434
-1.5
-2.3
hypothetical protein
compare
SMa2281
-1.4
-2.5
hypothetical protein
compare
SMc00981
-1.4
-6.8
ferredoxin protein
compare
SMc03153
-1.4
-3.0
keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase
compare
SMc00405
-1.4
-4.8
hypothetical protein
compare
SM
_b20773
-1.4
-4.1
GntR family transcriptional regulator
compare
SMc00914
-1.4
-4.1
oxidoreductase
compare
SMc01613
-1.4
-5.4
ribose-5-phosphate isomerase B
compare
SMc02485
-1.4
-1.6
signal peptide protein
compare
SMc02724
-1.4
-2.5
hypothetical protein
compare
SMc03993
-1.4
-4.8
hypothetical protein
compare
SMc00450
-1.3
-3.7
protoheme IX farnesyltransferase
compare
SMc02234
-1.3
-2.0
hypothetical protein
compare
SMc04296
-1.3
-0.8
cell division protein FtsZ
compare
SMc00987
-1.3
-1.6
hypothetical protein
compare
SMc02838
-1.3
-3.3
phosphoglyceromutase
compare
SMc03046
-1.3
-4.7
transcriptional regulator
compare
SMc04224
-1.3
-1.2
hypothetical protein
compare
SMc00712
-1.2
-2.0
hypothetical protein
compare
SMc02362
-1.2
-3.2
cytochrome c-type biogenesis protein CcmE
compare
SM
_b20823
-1.2
-5.2
cell surface saccharide synthesis protein
compare
SMc04348
-1.2
-1.3
transcriptional regulator
compare
SMc04213
-1.2
-1.8
diacylglycerol kinase
compare
SMc02786
-1.2
-5.3
translocase transmembrane protein
compare
SMc02050
-1.2
-3.2
trigger factor
compare
SMc02677
-1.1
-3.2
pyrroline-5-carboxylate reductase
compare
SMc00760
-1.1
-4.3
recombinase A
compare
SMc01852
-1.1
-6.9
pyrophosphate--fructose-6-phosphate 1-phosphotransferase
compare
SMc02573
-1.1
-1.9
hypothetical protein
compare
SMc03850
-1.1
-0.9
heme exporter D (cytochrome C-type biogenesis protein) transmembrane
compare
SMc02384
-1.1
-5.6
glycosyltransferase transmembrane protein
compare
SMc01364
-1.1
-1.0
DNA topoisomerase I
compare
SMc03941
-1.1
-3.0
hypothetical protein
compare
SMc00150
-1.1
-8.8
hypothetical protein
compare
SMc00073
-1.1
-1.5
hypothetical protein
compare
SMc00288
-1.1
-4.6
signal peptide protein
compare
SMa0431
-1.1
-1.4
hypothetical protein
compare
SMc03242
-1.1
-2.9
GTP-binding protein
compare
SMc01315
-1.1
-1.2
hypothetical protein
compare
SMc00579
-1.1
-4.1
dimethyladenosine transferase
compare
SMc02812
-1.0
-3.0
hypothetical protein
compare
SMc00821
-1.0
-1.5
hypothetical protein
compare
SMc00963
-1.0
-2.5
hypothetical protein
compare
SMc04024
-1.0
-4.6
membrane-bound lytic murein transglycosylase
compare
SMc01119
-1.0
-1.6
hypothetical protein
compare
SMc02834
-1.0
-2.5
methylglyoxal synthase
compare
SMc00067
-1.0
-4.9
outer-membranne lipoprotein
compare
SMa1878
-1.0
-2.7
transposase
compare
SM
_b20148
-1.0
-2.8
transcriptional regulator
compare
SM
_b20387
-1.0
-1.1
transcriptional regulator
compare
SMa0659
-1.0
-1.6
cytochrome c binding protein, carboxyl terminus
compare
SMc03006
-1.0
-1.1
chemotaxis regulator protein
compare
SMc01516
-1.0
-2.5
hypothetical protein
compare
SMc02114
-1.0
-2.2
hypothetical protein
compare
SMc02543
-0.9
-3.6
hypothetical protein
compare
SMc01220
-0.9
-3.4
lipopolysaccharide core biosynthesis glycosyl transferase
compare
SMc03050
-0.9
-1.9
flagellar biosynthesis regulatory protein FlaF
compare
Specific Phenotypes
None in this experiment
For Sinorhizobium meliloti 1021 in nutrient experiments