Experiment set5IT068 for Methanococcus maripaludis S2

Compare to:

Formate with nitrate 62.5 mM

200 most detrimental genes:

  gene name fitness t score description  
MMP_RS01830 +3.2 7.1 tRNA-Val compare
MMP_RS08215 +2.6 10.5 DUF483 domain-containing protein compare
MMP_RS03145 +2.6 18.5 fibrillarin-like rRNA/tRNA 2'-O-methyltransferase compare
MMP_RS08000 +2.6 22.0 methyl coenzyme M reductase-arginine methyltransferase Mmp10 compare
MMP_RS03140 +2.5 17.5 hypothetical protein compare
MMP_RS07075 +2.4 8.2 phosphomannomutase/phosphoglucomutase compare
MMP_RS07705 +2.4 14.1 transcriptional regulator compare
MMP_RS08320 +2.4 14.6 molybdopterin molybdotransferase MoeA compare
MMP_RS00120 +2.3 11.9 LysR family transcriptional regulator compare
MMP_RS07710 +2.2 9.5 cell division protein FtsZ compare
MMP_RS02010 +2.0 11.0 PHP domain-containing protein compare
MMP_RS07555 +2.0 2.2 monovalent cation/H+ antiporter subunit E compare
MMP_RS02885 +1.9 15.2 molybdopterin biosynthesis protein compare
MMP_RS05640 +1.9 7.6 UTP--glucose-1-phosphate uridylyltransferase GalU compare
MMP_RS06530 +1.9 8.7 bifunctional hexulose-6-phosphate synthase/ribonuclease regulator compare
MMP_RS03475 +1.8 1.5 hypothetical protein compare
MMP_RS06670 +1.8 5.2 glucose-6-phosphate isomerase compare
MMP_RS01725 +1.8 4.8 class I SAM-dependent methyltransferase family protein compare
MMP_RS08070 +1.7 9.0 DUF2096 domain-containing protein compare
MMP_RS07415 +1.7 8.6 molybdopterin-guanine dinucleotide biosynthesis protein MobB compare
MMP_RS05450 +1.6 5.7 CoB--CoM heterodisulfide reductase subunit C compare
MMP_RS07960 +1.6 10.1 sugar phosphate isomerase/epimerase compare
MMP_RS05445 +1.5 11.0 CoB--CoM heterodisulfide reductase subunit B compare
MMP_RS06370 +1.5 5.6 biotin synthase BioB compare
MMP_RS01985 +1.5 7.1 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS00850 +1.5 6.1 TIGR01177 family methyltransferase compare
MMP_RS01775 +1.4 3.3 TIGR00297 family protein compare
MMP_RS08690 +1.4 6.8 RNA-guided pseudouridylation complex pseudouridine synthase subunit Cbf5 compare
MMP_RS00560 +1.3 7.9 cation:proton antiporter compare
MMP_RS06555 +1.3 4.8 cupin domain-containing protein compare
MMP_RS08330 +1.3 5.6 NADH-quinone oxidoreductase subunit H compare
MMP_RS06980 +1.3 7.3 tRNA 2-thiocytidine biosynthesis TtcA family protein compare
MMP_RS00130 +1.3 1.8 nickel-responsive transcriptional regulator NikR compare
MMP_RS07180 +1.2 5.2 DEAD/DEAH box helicase compare
MMP_RS08660 +1.2 5.0 DHH family phosphoesterase compare
MMP_RS08155 +1.2 5.4 hypothetical protein compare
MMP_RS02605 +1.2 1.5 MotA/TolQ/ExbB proton channel family protein compare
MMP_RS01575 +1.1 4.9 aldolase compare
MMP_RS06705 +1.1 3.3 formate/nitrite transporter family protein compare
MMP_RS01895 +1.1 6.4 flippase compare
MMP_RS08760 +1.1 1.9 hypothetical protein compare
MMP_RS08075 +1.1 5.2 DUF749 domain-containing protein compare
MMP_RS07820 +1.1 4.6 UPF0104 family protein compare
MMP_RS01540 +1.1 3.1 DUF504 domain-containing protein compare
MMP_RS00325 +1.0 2.0 RNA-binding protein compare
MMP_RS07730 +1.0 2.4 pyruvate synthase subunit beta compare
MMP_RS04985 +1.0 2.9 DUF2180 family protein compare
MMP_RS00555 +1.0 5.0 MFS transporter compare
MMP_RS05425 +1.0 3.7 monovalent cation/H+ antiporter complex subunit F compare
MMP_RS06535 +1.0 3.5 2-oxoacid:acceptor oxidoreductase family protein compare
MMP_RS01960 +1.0 0.9 hypothetical protein compare
MMP_RS04035 +1.0 3.1 hypothetical protein compare
MMP_RS02355 +1.0 2.9 30S ribosomal protein S27ae compare
MMP_RS06720 +1.0 4.6 response regulator transcription factor compare
MMP_RS01650 +0.9 1.3 sulfurtransferase TusA family protein compare
MMP_RS00565 +0.9 2.7 CBS domain-containing protein compare
MMP_RS05095 +0.9 4.6 CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon compare
MMP_RS06550 +0.9 5.0 AMP-binding protein compare
MMP_RS05930 +0.9 1.6 3-isopropylmalate dehydratase large subunit compare
MMP_RS01460 +0.9 2.1 hypothetical protein compare
MMP_RS00750 +0.9 2.6 fumarate hydratase compare
MMP_RS09010 +0.9 4.4 hypothetical protein compare
MMP_RS06545 +0.8 3.7 ferredoxin family protein compare
MMP_RS06770 +0.8 4.3 DHH family phosphoesterase compare
MMP_RS01465 +0.8 1.6 hypothetical protein compare
MMP_RS08095 +0.8 4.5 dethiobiotin synthase compare
MMP_RS00975 +0.8 5.3 HD domain-containing protein compare
MMP_RS03155 +0.8 5.0 precorrin-6A reductase compare
MMP_RS00125 +0.8 1.6 DUF2798 domain-containing protein compare
MMP_RS06515 +0.8 2.6 UPF0489 family protein compare
MMP_RS00335 +0.8 3.5 5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH compare
MMP_RS09035 +0.8 1.7 hypothetical protein compare
MMP_RS02870 +0.8 2.9 hypothetical protein compare
MMP_RS03685 +0.8 4.6 Mrp/NBP35 family ATP-binding protein compare
MMP_RS08365 +0.8 2.8 energy conserving hydrogenase EhbF compare
MMP_RS06745 +0.7 1.9 DUF2119 domain-containing protein compare
MMP_RS06315 +0.7 0.8 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS08230 +0.7 3.1 50S ribosomal protein L11 methyltransferase compare
MMP_RS01370 +0.7 3.5 acetate--CoA ligase family protein compare
MMP_RS00450 +0.7 1.0 4Fe-4S binding protein compare
MMP_RS02790 +0.7 1.1 class III signal peptide-containing protein compare
MMP_RS03660 +0.7 5.5 MATE family efflux transporter compare
MMP_RS04875 +0.7 3.4 energy-converting hydrogenase B subunit P compare
MMP_RS06485 +0.7 0.9 zinc ribbon domain-containing protein compare
MMP_RS01905 +0.7 4.2 glycosyltransferase compare
MMP_RS00290 +0.7 4.1 hypothetical protein compare
MMP_RS01545 +0.7 0.7 CBS domain-containing protein compare
MMP_RS04720 +0.7 1.2 DedA family protein compare
MMP_RS08785 +0.7 0.8 RNA-protein complex protein Nop10 compare
MMP_RS06715 +0.7 5.1 cache domain-containing protein compare
MMP_RS00295 +0.7 1.6 gamma carbonic anhydrase family protein compare
MMP_RS05825 +0.7 2.6 peptidyl-prolyl cis-trans isomerase compare
MMP_RS06675 +0.7 3.6 ADP-specific phosphofructokinase compare
MMP_RS02975 +0.7 4.0 DUF2124 domain-containing protein compare
MMP_RS07875 +0.7 2.4 hypothetical protein compare
MMP_RS06905 +0.7 1.5 hypothetical protein compare
MMP_RS08685 +0.6 3.5 hypothetical protein compare
MMP_RS05055 +0.6 4.4 DUF166 domain-containing protein compare
MMP_RS05100 +0.6 4.6 CO dehydrogenase/acetyl-CoA synthase complex subunit alpha compare
MMP_RS04695 +0.6 3.8 selenide water dikinase SelD compare
MMP_RS04895 +0.6 4.8 AI-2E family transporter compare
MMP_RS06365 +0.6 1.4 hypothetical protein compare
MMP_RS04520 +0.6 1.7 nucleoside deaminase compare
MMP_RS05485 +0.6 3.4 cysteine--tRNA ligase compare
MMP_RS00670 +0.6 2.3 TIM barrel protein compare
MMP_RS04500 +0.6 3.7 adenosylmethionine--8-amino-7-oxononanoate transaminase compare
MMP_RS05955 +0.6 1.3 CoB--CoM heterodisulfide reductase subunit C compare
MMP_RS06495 +0.6 2.1 YkgJ family cysteine cluster protein compare
MMP_RS00935 +0.6 3.4 MATE family efflux transporter compare
MMP_RS01745 +0.6 2.5 AMP phosphorylase compare
MMP_RS06155 +0.6 1.6 DUF4186 domain-containing protein compare
MMP_RS03420 +0.6 2.1 acetolactate synthase small subunit compare
MMP_RS01525 +0.6 1.2 nucleoside-diphosphate kinase compare
MMP_RS00150 +0.6 2.6 AAA family ATPase compare
MMP_RS03770 +0.6 3.2 hydroxylamine reductase compare
MMP_RS05085 +0.6 2.4 AAA family ATPase compare
MMP_RS08310 +0.6 1.3 TMEM165/GDT1 family protein compare
MMP_RS07645 +0.5 1.3 aldehyde dehydrogenase family protein compare
MMP_RS05070 +0.5 2.3 4Fe-4S dicluster domain-containing protein compare
MMP_RS01240 +0.5 0.8 7-cyano-7-deazaguanine synthase QueC compare
MMP_RS00740 +0.5 1.6 cyclase family protein compare
MMP_RS01910 +0.5 2.2 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
MMP_RS08275 +0.5 2.9 hypothetical protein compare
MMP_RS01470 +0.5 1.9 ATP-binding cassette domain-containing protein compare
MMP_RS03150 +0.5 2.9 phosphoglycerate mutase compare
MMP_RS05645 +0.5 2.9 AEC family transporter compare
MMP_RS07135 +0.5 2.4 coenzyme F420 hydrogenase subunit beta compare
MMP_RS02290 +0.5 1.7 MBL fold metallo-hydrolase compare
MMP_RS07095 +0.5 1.4 PspC domain-containing protein compare
MMP_RS08100 +0.5 1.5 8-amino-7-oxononanoate synthase compare
MMP_RS06930 +0.5 2.9 MBL fold metallo-hydrolase compare
MMP_RS05720 +0.5 1.5 signal recognition particle subunit SRP19/SEC65 family protein compare
MMP_RS02135 +0.5 1.0 DUF5612 domain-containing protein compare
MMP_RS07130 +0.5 2.0 coenzyme F420 hydrogenase subunit gamma compare
MMP_RS05090 +0.5 2.8 CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta compare
MMP_RS02015 +0.5 2.5 amidohydrolase compare
MMP_RS00845 +0.5 3.0 acetate--CoA ligase compare
MMP_RS07735 +0.5 0.4 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS01580 +0.5 3.1 PQQ-binding-like beta-propeller repeat protein compare
MMP_RS00965 +0.5 1.3 hypothetical protein compare
MMP_RS06435 +0.5 2.3 CBS domain-containing protein compare
MMP_RS07955 +0.5 2.0 FumA C-terminus/TtdB family hydratase beta subunit compare
MMP_RS02265 +0.5 1.6 nitroreductase family protein compare
MMP_RS08655 +0.5 3.5 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS07890 +0.5 1.4 OB-fold nucleic acid binding domain-containing protein compare
MMP_RS01930 +0.5 2.8 hypothetical protein compare
MMP_RS01955 +0.5 1.0 hypothetical protein compare
MMP_RS07720 +0.5 3.3 4Fe-4S binding protein compare
MMP_RS00705 +0.5 1.0 hypothetical protein compare
MMP_RS06500 +0.5 2.3 ATP-binding protein compare
MMP_RS05435 +0.5 2.2 5'/3'-nucleotidase SurE compare
MMP_RS02310 +0.5 0.9 RimK-like ATPgrasp N-terminal domain-containing protein compare
MMP_RS03665 +0.4 2.9 PadR family transcriptional regulator compare
MMP_RS05060 +0.4 2.6 AAA family ATPase compare
MMP_RS09055 +0.4 0.5 CAP domain-containing protein compare
MMP_RS00770 +0.4 1.3 hypothetical protein compare
MMP_RS06140 +0.4 1.6 radical SAM protein compare
MMP_RS03270 +0.4 1.9 ADP-ribosylglycohydrolase family protein compare
MMP_RS02345 +0.4 1.5 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS06540 +0.4 1.1 3-methyl-2-oxobutanoate dehydrogenase subunit VorB compare
MMP_RS00530 +0.4 2.1 tRNA pseudouridine(54/55) synthase Pus10 compare
MMP_RS06445 +0.4 1.0 DUF89 domain-containing protein compare
MMP_RS03405 +0.4 1.8 RNA 3'-terminal phosphate cyclase compare
MMP_RS08175 +0.4 1.6 7-cyano-7-deazaguanine synthase compare
MMP_RS03755 +0.4 2.1 MarR family transcriptional regulator compare
MMP_RS01445 +0.4 1.7 hypothetical protein compare
MMP_RS02740 +0.4 1.2 hypothetical protein compare
MMP_RS01620 +0.4 0.9 hypothetical protein compare
MMP_RS05265 +0.4 0.7 2-isopropylmalate synthase compare
MMP_RS00135 +0.4 1.8 DUF2121 domain-containing protein compare
MMP_RS02880 +0.4 2.0 AmmeMemoRadiSam system radical SAM enzyme compare
MMP_RS08090 +0.4 1.2 hypothetical protein compare
MMP_RS04625 +0.4 2.5 DEAD/DEAH box helicase compare
MMP_RS06000 +0.4 1.4 divalent-cation tolerance protein CutA compare
MMP_RS01940 +0.4 0.6 MoxR family ATPase compare
MMP_RS07835 +0.4 1.5 TldD/PmbA family protein compare
MMP_RS01440 +0.4 1.8 NAAT family transporter compare
MMP_RS06520 +0.4 1.6 DUF1786 domain-containing protein compare
MMP_RS04280 +0.4 1.9 coenzyme F420-non-reducing hydrogenase subunit gamma compare
MMP_RS05035 +0.4 1.8 hypothetical protein compare
MMP_RS05080 +0.4 2.4 acetyl-CoA decarbonylase/synthase complex subunit delta compare
MMP_RS01140 +0.4 1.4 molybdate ABC transporter permease subunit compare
MMP_RS01190 +0.4 1.7 cadmium-translocating P-type ATPase compare
MMP_RS02480 +0.4 0.7 hypothetical protein compare
MMP_RS04105 +0.3 1.9 MarR family transcriptional regulator compare
MMP_RS00100 +0.3 2.6 tRNA pseudouridine(13) synthase TruD compare
MMP_RS00795 +0.3 1.4 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS00250 +0.3 2.3 Flp pilus assembly complex ATPase component TadA compare
MMP_RS00930 +0.3 1.3 ABC transporter permease compare
MMP_RS02470 +0.3 0.6 helix-turn-helix transcriptional regulator compare
MMP_RS02475 +0.3 0.8 hypothetical protein compare
MMP_RS04635 +0.3 1.2 GNAT family N-acetyltransferase compare
MMP_RS08105 +0.3 1.5 6-carboxyhexanoate--CoA ligase compare
MMP_RS00385 +0.3 1.3 P-II family nitrogen regulator compare
MMP_RS05940 +0.3 1.8 corrinoid protein compare
MMP_RS05075 +0.3 2.4 acetyl-CoA decarbonylase/synthase complex subunit gamma compare
MMP_RS09045 +0.3 2.3 class III signal peptide-containing protein compare
MMP_RS02235 +0.3 0.8 CBS domain-containing protein compare
MMP_RS03335 +0.3 1.7 ABC transporter permease compare
MMP_RS08535 +0.3 1.8 bis-aminopropyl spermidine synthase family protein compare


Specific Phenotypes

For 10 genes in this experiment

For stress Sodium nitrate in Methanococcus maripaludis S2

For stress Sodium nitrate across organisms