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Experiment set5IT067 for
Sinorhizobium meliloti 1021
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Min media with glucose
200 most important genes:
gene
name
fitness
t score
description
SMc01726
-7.9
-5.5
acetylglutamate kinase
compare
SMc00236
-7.4
-5.1
Indole-3-glycerol phosphate synthase
compare
SMc02899
-6.9
-10.6
prephenate dehydratase
compare
SMc02766
-6.9
-14.0
tryptophan synthase subunit beta
compare
SMc04405
-6.9
-6.7
3-isopropylmalate dehydrogenase
compare
SMc00235
-6.8
-8.0
anthranilate phosphoribosyltransferase
compare
SMc01494
-6.6
-10.1
phosphoserine phosphatase
compare
SMc04045
-6.6
-6.4
dihydroxy-acid dehydratase
compare
SMc00640
-6.5
-6.4
phosphoserine aminotransferase
compare
SMc02245
-6.5
-6.3
dihydroorotate dehydrogenase 2
compare
SMc03797
-6.5
-9.9
homoserine O-succinyltransferase
compare
SMc02767
-6.5
-8.8
N-(5'-phosphoribosyl)anthranilate isomerase
compare
SMc02574
-6.4
-4.4
imidazoleglycerol-phosphate dehydratase
compare
SMc02137
-6.4
-4.4
ornithine carbamoyltransferase
compare
SMc01801
-6.4
-3.9
N-acetylglutamylphosphate reductase (EC 1.2.1.38)
(from data)
compare
SMc01843
-6.4
-10.6
5,10-methylenetetrahydrofolate reductase
compare
SMc02572
-6.3
-5.2
imidazole glycerol phosphate synthase subunit HisH
compare
SMc00917
-6.3
-4.4
ATP phosphoribosyltransferase (EC 2.4.2.17)
(from data)
compare
SMc00092
-6.2
-10.4
phosphoadenosine phosphosulfate reductase
compare
SMa1635
-6.2
-2.2
hypothetical protein
compare
SMc02725
-6.2
-12.5
anthranilate synthase
compare
SMc02717
-6.1
-10.2
2-isopropylmalate synthase
compare
SMc04002
-6.1
-8.3
phosphoribosylaminoimidazole carboxylase ATPase subunit
compare
SMc02123
-6.0
-3.8
required for sulfate utilization, putative electron transport protein for sulfite reductase
(from data)
compare
SMc04005
-6.0
-5.9
pyruvate kinase
compare
SMc03823
-6.0
-10.8
isopropylmalate isomerase large subunit
compare
SMc00488
-5.9
-17.9
phosphoribosylformylglycinamidine synthase II
compare
SMc00131
-5.9
-13.8
transcriptional regulator
compare
SMc00918
-5.9
-9.9
ATP phosphoribosyltransferase regulatory subunit
compare
SMc02217
-5.9
-5.8
O-succinylhomoserine sulfhydrylase
compare
SMc01004
-5.9
-11.3
phosphoribosyl-AMP cyclohydrolase
compare
SMc01431
-5.9
-12.5
acetolactate synthase 3 catalytic subunit
compare
SMc01361
-5.8
-5.7
dihydroorotase
compare
SMc00494
-5.8
-2.1
phosphoribosylformylglycinamidine synthase subunit PurS
compare
SMc00293
-5.8
-11.7
homoserine dehydrogenase
compare
SM
_b21177
-5.7
-5.5
phosphate uptake ABC transporter ATP-binding protein
compare
SMc04028
-5.7
-16.4
glutamate synthase
compare
SMc02765
-5.5
-11.6
tryptophan synthase subunit alpha
compare
SMc01054
-5.5
-5.2
required for sulfate utilization, putative electron source for sulfite reductase CysI
(from data)
compare
SMc00090
-5.3
-8.2
sulfate adenylyltransferase
compare
SMc03070
-5.3
-7.2
glucose-6-phosphate 1-dehydrogenase
compare
SMc00554
-5.3
-8.1
amidophosphoribosyltransferase
compare
SMc01360
-5.3
-3.6
aspartate carbamoyltransferase catalytic subunit
compare
SMc02165
-5.2
-8.7
orotate phosphoribosyltransferase
compare
SMc03777
-5.2
-7.1
gamma-glutamyl phosphate reductase
compare
SM
_b21175
-5.1
-5.2
phosphate uptake ABC transporter permease
compare
SMc00091
-5.0
-13.4
sulfate adenylyltransferase
compare
SM
_b21174
-5.0
-4.4
phosphate uptake ABC transporter permease
compare
SMc02569
-5.0
-5.8
imidazole glycerol phosphate synthase subunit HisF
compare
SMc03112
-5.0
-16.7
B12-dependent methionine synthase
compare
SMc00615
-5.0
-7.4
phosphoribosylaminoimidazole synthetase
compare
SMc04026
-4.9
-8.5
glutamate synthase
compare
SMc02124
-4.9
-14.7
nitrite reductase
compare
SMc03981
-4.9
-5.8
phosphoglycerate kinase
compare
SMc00993
-4.9
-10.8
phosphoribosylamine--glycine ligase
compare
SMc03895
-4.8
-17.1
pyruvate carboxylase
compare
SMc03826
-4.8
-3.3
argininosuccinate synthase
compare
SMc02755
-4.7
-7.9
S-adenosyl-L-homocysteine hydrolase
compare
SMc02570
-4.7
-7.9
1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16)
(from data)
compare
SMc02138
-4.7
-12.5
acetylornithine transaminase
compare
SMc00876
-4.7
-7.8
ATP-binding MRP protein
compare
SMc02166
-4.7
-11.2
dihydroorotase
compare
SMc02307
-4.7
-6.4
histidinol dehydrogenase
compare
SMc00711
-4.7
-5.1
cyclohexadienyl dehydrogenase
compare
SMc03229
-4.6
-2.8
NAD(P)H-dependent glycerol-3-phosphate dehydrogenase
compare
SMc00614
-4.6
-9.2
phosphoribosylglycinamide formyltransferase
compare
SMc00493
-4.5
-6.5
phosphoribosylformylglycinamidine synthase I
compare
SMc00495
-4.4
-4.4
phosphoribosylaminoimidazolesuccinocarboxamide synthase
compare
SMc04088
-4.3
-8.4
bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
compare
SMc04001
-4.2
-1.5
phosphoribosylaminoimidazole carboxylase catalytic subunit protein
compare
SMc02425
-4.2
-5.6
transcriptional regulator
compare
SMc00412
-4.2
-6.3
orotidine 5'-phosphate decarboxylase
compare
SM
_b21176
-4.1
-5.5
phosphate uptake ABC transporter substrate-binding protein precursor
compare
SMc02707
-4.0
-6.2
hypothetical protein
compare
SMc03068
-3.9
-12.2
phosphogluconate dehydratase
compare
SMc03763
-3.9
-2.7
cytosine-specific methyltransferase
compare
SMc03776
-3.8
-3.8
gamma-glutamyl kinase
compare
SMc01881
-3.8
-4.1
3-methyl-2-oxobutanoate hydroxymethyltransferase
compare
SM
_b20903
-3.7
-8.8
sugar uptake ABC transporter permease
compare
SMc01206
-3.7
-3.1
queuine tRNA-ribosyltransferase
compare
SMc04346
-3.7
-5.2
ketol-acid reductoisomerase
compare
SMc03979
-3.7
-2.5
glyceraldehyde-3-phosphate dehydrogenase
compare
SMc01053
-3.6
-5.5
siroheme synthase
compare
SMc00641
-3.6
-5.6
D-3-phosphoglycerate dehydrogenase
compare
SMc01569
-3.6
-1.8
carbamoyl phosphate synthase small subunit
compare
SMc00294
-3.5
-12.2
aminotransferase
compare
SM
_b20902
-3.5
-15.7
sugar uptake ABC transporter substrate-binding protein precursor
compare
SM
_b20904
-3.5
-5.3
sugar uptake ABC transporter ATP-binding protein
compare
SMc01430
-3.4
-5.1
acetolactate synthase 3 regulatory subunit
compare
SMc03978
-3.4
-3.3
transketolase
compare
SMc00914
-3.4
-8.3
oxidoreductase
compare
SMc02909
-3.4
-3.9
transglycosylase transmembrane protein
compare
SMc03795
-3.4
-1.7
isopropylmalate isomerase small subunit
compare
SMc00017
-3.3
-1.6
homoserine kinase
compare
SMc00815
-3.2
-2.8
inosine 5'-monophosphate dehydrogenase
compare
SMc01215
-3.2
-2.2
carbamoyl phosphate synthase large subunit
compare
SMc02246
-3.1
-1.1
hypothetical protein
compare
SMc01124
-3.1
-8.8
PII uridylyl-transferase
compare
SMc01578
-3.1
-12.9
aspartate aminotransferase
compare
SMc01147
-3.1
-4.9
coproporphyrinogen III oxidase
compare
SMc01770
-2.9
-1.8
serine hydroxymethyltransferase
compare
SMc02058
-2.9
-5.0
YAJC protein
compare
SMc00709
-2.9
-6.0
hypothetical protein
compare
SMc01880
-2.8
-3.3
pantoate--beta-alanine ligase
compare
SMc02835
-2.8
-6.3
glucokinase
compare
SMc01183
-2.7
-2.3
LexA repressor
compare
SMc00414
-2.7
-9.0
hypothetical protein
compare
SMa0789
-2.7
-4.4
GntR family transcriptional regulator
compare
SMc01441
-2.7
-5.0
membrane bound protease
compare
SMc02451
-2.6
-2.8
hypothetical protein
compare
SMc02753
-2.6
-2.4
PTS system transporter subunit IIA
compare
SMc01440
-2.6
-6.6
hydrolase serine protease transmembrane protein
compare
SMc03974
-2.5
-5.4
hypothetical protein
compare
SMc01028
-2.5
-12.0
phosphopyruvate hydratase
compare
SMc02983
-2.4
-6.1
ornithine, DAP, or arginine decarboxylase
compare
SMc03924
-2.4
-7.4
glycogen synthase
compare
SMc00492
-2.4
-1.4
hypothetical protein
compare
SMc02685
-2.4
-5.0
hypothetical protein
compare
SMc00088
-2.4
-2.2
hypothetical protein
compare
SMc00361
-2.4
-2.6
hypothetical protein
compare
SMc00295
-2.3
-2.1
hypothetical protein
compare
SMc00450
-2.3
-4.7
protoheme IX farnesyltransferase
compare
SMc01842
-2.3
-2.7
methyltransferase transcription regulator protein
compare
SMc00353
-2.3
-2.7
transmembrane protein
compare
SMc01187
-2.3
-2.0
rare lipoprotein A
compare
SMc02833
-2.2
-3.3
penicillin-insensitive murein endopeptidase
compare
SMc02683
-2.2
-2.6
hypothetical protein
compare
SMc01208
-2.2
-4.2
peptidyl-prolyl cis-trans isomerase B protein
compare
SMc00838
-2.1
-4.7
hypothetical protein
compare
SMc01364
-2.1
-1.4
DNA topoisomerase I
compare
SMc00982
-2.1
-6.7
dioxygenase
compare
SMc03069
-2.0
-1.5
6-phosphogluconolactonase
compare
SMc01097
-2.0
-6.0
hypothetical protein
compare
SMa1118
-1.8
-1.7
HspC2 heat shock protein
compare
SMc00981
-1.8
-6.9
ferredoxin protein
compare
SMc03100
-1.8
-1.6
hypothetical protein
compare
SMc02115
-1.8
-1.6
hypothetical protein
compare
SMc02856
-1.8
-11.2
penicillin-binding protein
compare
SMc01850
-1.7
-3.8
hypothetical protein
compare
SMc00302
-1.6
-2.3
hypothetical protein
compare
SMc02641
-1.6
-3.4
UDP-glucose 6-dehydrogenase
compare
SMc01438
-1.6
-6.0
protease precursor signal peptide protein
compare
SMc02838
-1.6
-4.7
phosphoglyceromutase
compare
SMc03153
-1.6
-2.8
keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase
compare
SMc04296
-1.6
-1.4
cell division protein FtsZ
compare
SMc03140
-1.6
-4.6
transcriptional regulator
compare
SMc00579
-1.5
-4.2
dimethyladenosine transferase
compare
SM
_b20823
-1.5
-5.9
cell surface saccharide synthesis protein
compare
SMc04330
-1.5
-2.8
trimethylamine methyltransferase
compare
SMc00712
-1.5
-2.9
hypothetical protein
compare
SMc01368
-1.5
-4.3
transport transmembrane protein
compare
SMc03028
-1.5
-2.1
flagellar basal body rod protein FlgC
compare
SMc02505
-1.4
-1.7
hypothetical protein
compare
SMc02861
-1.4
-1.9
phosphate transporter
compare
SMc02543
-1.4
-7.1
hypothetical protein
compare
SMc00619
-1.4
-2.4
hypothetical protein
compare
SMc02640
-1.4
-4.6
UDP-glucuronic acid epimerase
compare
SMc00012
-1.4
-1.6
cytochrome C oxidase assembly protein
compare
SMc04213
-1.4
-1.8
diacylglycerol kinase
compare
SMc02385
-1.4
-3.0
hypothetical protein
compare
SMc02582
-1.4
-3.6
hypothetical protein
compare
SMc02102
-1.3
-4.2
hypothetical protein
compare
SMc02114
-1.3
-3.4
hypothetical protein
compare
SMc02724
-1.3
-2.3
hypothetical protein
compare
SMc01857
-1.3
-1.9
cell division protein MraZ
compare
SMc01613
-1.3
-4.9
ribose-5-phosphate isomerase B
compare
SMc00987
-1.3
-2.5
hypothetical protein
compare
SMc03072
-1.3
-2.3
hypothetical protein
compare
SMa0211
-1.3
-1.3
hypothetical protein
compare
SMc03967
-1.2
-1.2
Holliday junction resolvase
compare
SMc01280
-1.2
-1.9
protease
compare
SM
_b20392
-1.2
-3.4
transcriptional regulator NanR
compare
SMc02495
-1.2
-1.6
translaldolase
compare
SMc04024
-1.2
-5.7
membrane-bound lytic murein transglycosylase
compare
SMc02232
-1.1
-2.8
hypothetical protein
compare
SMc02778
-1.1
-1.0
hydroxyacid aldolase
compare
SMc00296
-1.1
-6.4
POLY3-hydroxybutyrate polymerase
compare
SMc03993
-1.1
-3.3
hypothetical protein
compare
SMc00150
-1.1
-8.5
hypothetical protein
compare
SMa5010
-1.1
-1.1
hypothetical protein
compare
SMc04348
-1.1
-1.2
transcriptional regulator
compare
SMc01579
-1.1
-1.2
hypothetical protein
compare
SM
_b20773
-1.1
-2.4
GntR family transcriptional regulator
compare
SMa0714
-1.1
-3.6
ABC transporter ATP-binding protein
compare
SM
_b21480
-1.1
-1.1
hypothetical protein
compare
SMc03046
-1.1
-4.4
transcriptional regulator
compare
SMc04000
-1.1
-1.2
hypothetical protein
compare
SMc00405
-1.1
-4.4
hypothetical protein
compare
SMc02812
-1.1
-2.0
hypothetical protein
compare
SMc02227
-1.1
-4.4
fatty oxidation complex enoyl-COA hydratase/3-hydroxyacyl-COA dehydrogenase/3-hydroxybutyryl-COA epimerase
compare
SMc02434
-1.0
-2.2
hypothetical protein
compare
SMc00963
-1.0
-2.6
hypothetical protein
compare
SMc00060
-1.0
-3.7
hypothetical protein
compare
SMc01220
-1.0
-4.0
lipopolysaccharide core biosynthesis glycosyl transferase
compare
SMc01852
-1.0
-5.4
pyrophosphate--fructose-6-phosphate 1-phosphotransferase
compare
SMc02147
-1.0
-3.1
phosphate regulon sensor histidine kinase transmembrane protein
compare
SMc01461
-1.0
-4.4
DNA helicase II protein
compare
SMc01568
-1.0
-1.4
hypothetical protein
compare
SMc02985
-1.0
-6.5
hypothetical protein
compare
SMc00689
-1.0
-3.8
lipoprotein
compare
Specific Phenotypes
None in this experiment
For Sinorhizobium meliloti 1021 in nutrient experiments