Experiment set5IT067 for Methanococcus maripaludis S2

Compare to:

Formate with nitrate 62.5 mM

200 most detrimental genes:

  gene name fitness t score description  
MMP_RS08000 +3.4 29.5 methyl coenzyme M reductase-arginine methyltransferase Mmp10 compare
MMP_RS08215 +3.2 13.8 DUF483 domain-containing protein compare
MMP_RS01830 +3.2 3.9 tRNA-Val compare
MMP_RS07075 +3.1 10.0 phosphomannomutase/phosphoglucomutase compare
MMP_RS00130 +2.9 3.9 nickel-responsive transcriptional regulator NikR compare
MMP_RS05640 +2.8 12.8 UTP--glucose-1-phosphate uridylyltransferase GalU compare
MMP_RS06720 +2.8 12.7 response regulator transcription factor compare
MMP_RS02010 +2.7 13.4 PHP domain-containing protein compare
MMP_RS08320 +2.7 13.8 molybdopterin molybdotransferase MoeA compare
MMP_RS01960 +2.6 1.6 hypothetical protein compare
MMP_RS06715 +2.5 16.0 cache domain-containing protein compare
MMP_RS07710 +2.5 11.2 cell division protein FtsZ compare
MMP_RS06705 +2.4 6.5 formate/nitrite transporter family protein compare
MMP_RS01725 +2.4 6.6 class I SAM-dependent methyltransferase family protein compare
MMP_RS07705 +2.3 13.5 transcriptional regulator compare
MMP_RS02885 +2.3 17.5 molybdopterin biosynthesis protein compare
MMP_RS03145 +2.1 11.1 fibrillarin-like rRNA/tRNA 2'-O-methyltransferase compare
MMP_RS03140 +2.1 16.1 hypothetical protein compare
MMP_RS00120 +2.1 10.1 LysR family transcriptional regulator compare
MMP_RS08070 +1.9 8.9 DUF2096 domain-containing protein compare
MMP_RS03475 +1.8 1.2 hypothetical protein compare
MMP_RS06670 +1.8 4.9 glucose-6-phosphate isomerase compare
MMP_RS01775 +1.8 3.5 TIGR00297 family protein compare
MMP_RS01985 +1.7 5.8 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS08595 +1.7 1.7 flagellar protein C compare
MMP_RS07415 +1.7 8.1 molybdopterin-guanine dinucleotide biosynthesis protein MobB compare
MMP_RS02345 +1.7 3.6 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS05425 +1.6 5.3 monovalent cation/H+ antiporter complex subunit F compare
MMP_RS06530 +1.6 6.5 bifunctional hexulose-6-phosphate synthase/ribonuclease regulator compare
MMP_RS06980 +1.5 7.8 tRNA 2-thiocytidine biosynthesis TtcA family protein compare
MMP_RS02355 +1.5 3.4 30S ribosomal protein S27ae compare
MMP_RS02605 +1.5 1.7 MotA/TolQ/ExbB proton channel family protein compare
MMP_RS00560 +1.4 7.9 cation:proton antiporter compare
MMP_RS07960 +1.4 8.1 sugar phosphate isomerase/epimerase compare
MMP_RS00450 +1.4 1.2 4Fe-4S binding protein compare
MMP_RS08330 +1.4 5.2 NADH-quinone oxidoreductase subunit H compare
MMP_RS05445 +1.4 7.1 CoB--CoM heterodisulfide reductase subunit B compare
MMP_RS02340 +1.3 1.7 DNA-directed RNA polymerase subunit E'' compare
MMP_RS05450 +1.3 4.2 CoB--CoM heterodisulfide reductase subunit C compare
MMP_RS01895 +1.3 6.9 flippase compare
MMP_RS07820 +1.2 4.0 UPF0104 family protein compare
MMP_RS04710 +1.2 1.9 hypothetical protein compare
MMP_RS00850 +1.1 3.6 TIGR01177 family methyltransferase compare
MMP_RS01575 +1.1 5.9 aldolase compare
MMP_RS06770 +1.1 6.7 DHH family phosphoesterase compare
MMP_RS06370 +1.1 3.5 biotin synthase BioB compare
MMP_RS07555 +1.1 0.9 monovalent cation/H+ antiporter subunit E compare
MMP_RS00125 +1.1 2.0 DUF2798 domain-containing protein compare
MMP_RS08690 +1.1 5.5 RNA-guided pseudouridylation complex pseudouridine synthase subunit Cbf5 compare
MMP_RS00325 +1.1 1.7 RNA-binding protein compare
MMP_RS01460 +1.1 2.2 hypothetical protein compare
MMP_RS08440 +1.1 2.4 cell division protein SepF compare
MMP_RS02235 +1.1 2.5 CBS domain-containing protein compare
MMP_RS01370 +1.1 5.0 acetate--CoA ligase family protein compare
MMP_RS06940 +1.1 2.4 polyprenyl diphosphate synthase compare
MMP_RS08155 +1.1 3.7 hypothetical protein compare
MMP_RS04875 +1.0 3.5 energy-converting hydrogenase B subunit P compare
MMP_RS07180 +1.0 4.0 DEAD/DEAH box helicase compare
MMP_RS03155 +1.0 5.9 precorrin-6A reductase compare
MMP_RS01545 +1.0 0.9 CBS domain-containing protein compare
MMP_RS01905 +1.0 6.2 glycosyltransferase compare
MMP_RS01910 +1.0 4.6 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
MMP_RS02480 +1.0 1.4 hypothetical protein compare
MMP_RS00290 +1.0 5.1 hypothetical protein compare
MMP_RS00945 +1.0 1.2 PadR family transcriptional regulator compare
MMP_RS05095 +1.0 4.8 CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon compare
MMP_RS08660 +0.9 4.4 DHH family phosphoesterase compare
MMP_RS00040 +0.9 3.3 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS00740 +0.9 3.0 cyclase family protein compare
MMP_RS01745 +0.9 5.1 AMP phosphorylase compare
MMP_RS05090 +0.9 4.3 CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta compare
MMP_RS05070 +0.9 5.8 4Fe-4S dicluster domain-containing protein compare
MMP_RS00295 +0.9 2.2 gamma carbonic anhydrase family protein compare
MMP_RS06535 +0.9 3.7 2-oxoacid:acceptor oxidoreductase family protein compare
MMP_RS01540 +0.9 1.9 DUF504 domain-containing protein compare
MMP_RS05765 +0.9 4.4 M42 family metallopeptidase compare
MMP_RS01525 +0.8 1.6 nucleoside-diphosphate kinase compare
MMP_RS08760 +0.8 1.7 hypothetical protein compare
MMP_RS09010 +0.8 5.0 hypothetical protein compare
MMP_RS00975 +0.8 4.9 HD domain-containing protein compare
MMP_RS00530 +0.8 3.2 tRNA pseudouridine(54/55) synthase Pus10 compare
MMP_RS08075 +0.8 3.4 DUF749 domain-containing protein compare
MMP_RS03660 +0.8 5.0 MATE family efflux transporter compare
MMP_RS05100 +0.7 5.4 CO dehydrogenase/acetyl-CoA synthase complex subunit alpha compare
MMP_RS05850 +0.7 2.6 Ldh family oxidoreductase compare
MMP_RS06345 +0.7 5.4 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS02310 +0.7 1.2 RimK-like ATPgrasp N-terminal domain-containing protein compare
MMP_RS06315 +0.7 0.6 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS08365 +0.7 2.9 energy conserving hydrogenase EhbF compare
MMP_RS00985 +0.7 2.3 CDC48 family AAA ATPase compare
MMP_RS00555 +0.7 3.3 MFS transporter compare
MMP_RS05720 +0.7 2.5 signal recognition particle subunit SRP19/SEC65 family protein compare
MMP_RS07955 +0.7 3.9 FumA C-terminus/TtdB family hydratase beta subunit compare
MMP_RS06445 +0.7 2.2 DUF89 domain-containing protein compare
MMP_RS05645 +0.7 3.4 AEC family transporter compare
MMP_RS03685 +0.7 3.4 Mrp/NBP35 family ATP-binding protein compare
MMP_RS05930 +0.7 1.1 3-isopropylmalate dehydratase large subunit compare
MMP_RS08315 +0.7 0.9 S-methyl-5-thioribose-1-phosphate isomerase compare
MMP_RS06745 +0.7 1.8 DUF2119 domain-containing protein compare
MMP_RS01945 +0.7 2.1 DUF4350 domain-containing protein compare
MMP_RS01470 +0.7 1.5 ATP-binding cassette domain-containing protein compare
MMP_RS04695 +0.7 3.9 selenide water dikinase SelD compare
MMP_RS02290 +0.7 2.1 MBL fold metallo-hydrolase compare
MMP_RS07095 +0.7 1.4 PspC domain-containing protein compare
MMP_RS08340 +0.6 2.1 4Fe-4S binding protein compare
MMP_RS01940 +0.6 1.4 MoxR family ATPase compare
MMP_RS09035 +0.6 1.2 hypothetical protein compare
MMP_RS07730 +0.6 1.2 pyruvate synthase subunit beta compare
MMP_RS05055 +0.6 3.9 DUF166 domain-containing protein compare
MMP_RS08785 +0.6 0.6 RNA-protein complex protein Nop10 compare
MMP_RS04985 +0.6 1.5 DUF2180 family protein compare
MMP_RS05075 +0.6 4.4 acetyl-CoA decarbonylase/synthase complex subunit gamma compare
MMP_RS01100 +0.6 0.9 ABC transporter ATP-binding protein compare
MMP_RS05060 +0.6 3.6 AAA family ATPase compare
MMP_RS02975 +0.6 2.9 DUF2124 domain-containing protein compare
MMP_RS06555 +0.6 1.9 cupin domain-containing protein compare
MMP_RS05080 +0.6 4.0 acetyl-CoA decarbonylase/synthase complex subunit delta compare
MMP_RS00670 +0.6 2.2 TIM barrel protein compare
MMP_RS07835 +0.6 2.1 TldD/PmbA family protein compare
MMP_RS00965 +0.6 1.5 hypothetical protein compare
MMP_RS02015 +0.6 2.1 amidohydrolase compare
MMP_RS04035 +0.6 1.6 hypothetical protein compare
MMP_RS06550 +0.6 2.6 AMP-binding protein compare
MMP_RS02870 +0.6 3.2 hypothetical protein compare
MMP_RS05485 +0.6 2.7 cysteine--tRNA ligase compare
MMP_RS05085 +0.6 2.3 AAA family ATPase compare
MMP_RS06545 +0.6 2.1 ferredoxin family protein compare
MMP_RS01955 +0.6 0.8 hypothetical protein compare
MMP_RS02930 +0.6 1.3 class I SAM-dependent methyltransferase compare
MMP_RS07720 +0.6 3.0 4Fe-4S binding protein compare
MMP_RS06520 +0.6 2.2 DUF1786 domain-containing protein compare
MMP_RS03770 +0.6 2.7 hydroxylamine reductase compare
MMP_RS06680 +0.5 4.0 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS06515 +0.5 1.5 UPF0489 family protein compare
MMP_RS00335 +0.5 1.9 5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH compare
MMP_RS04520 +0.5 1.6 nucleoside deaminase compare
MMP_RS06525 +0.5 0.7 YciI family protein compare
MMP_RS01465 +0.5 1.1 hypothetical protein compare
MMP_RS02130 +0.5 1.9 zinc metalloprotease HtpX compare
MMP_RS01020 +0.5 0.5 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS07850 +0.5 1.6 prephenate dehydratase compare
MMP_RS07135 +0.5 2.2 coenzyme F420 hydrogenase subunit beta compare
MMP_RS04895 +0.5 3.8 AI-2E family transporter compare
MMP_RS03665 +0.5 3.2 PadR family transcriptional regulator compare
MMP_RS06500 +0.5 2.9 ATP-binding protein compare
MMP_RS08230 +0.5 2.1 50S ribosomal protein L11 methyltransferase compare
MMP_RS00565 +0.5 1.0 CBS domain-containing protein compare
MMP_RS00150 +0.5 1.9 AAA family ATPase compare
MMP_RS01950 +0.5 2.3 hypothetical protein compare
MMP_RS01930 +0.5 2.7 hypothetical protein compare
MMP_RS02805 +0.5 0.6 HEPN domain-containing protein compare
MMP_RS01840 +0.5 2.1 TIGR00289 family protein compare
MMP_RS00935 +0.5 2.8 MATE family efflux transporter compare
MMP_RS00940 +0.5 2.8 daunorubicin resistance protein DrrA family ABC transporter ATP-binding protein compare
MMP_RS01935 +0.5 2.7 DUF58 domain-containing protein compare
MMP_RS06310 +0.5 1.3 NAD(P)/FAD-dependent oxidoreductase compare
MMP_RS06975 +0.5 1.1 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS04105 +0.5 1.9 MarR family transcriptional regulator compare
MMP_RS06435 +0.5 1.8 CBS domain-containing protein compare
MMP_RS05825 +0.5 1.7 peptidyl-prolyl cis-trans isomerase compare
MMP_RS00135 +0.5 2.1 DUF2121 domain-containing protein compare
MMP_RS01650 +0.5 0.5 sulfurtransferase TusA family protein compare
MMP_RS06685 +0.5 3.2 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS06725 +0.4 2.4 hypothetical protein compare
MMP_RS03015 +0.4 2.9 GTP 3' 8-cyclase MoaA compare
MMP_RS00825 +0.4 0.9 fumarylacetoacetate hydrolase family protein compare
MMP_RS05665 +0.4 2.0 phosphate ABC transporter permease subunit PstC compare
MMP_RS07890 +0.4 1.0 OB-fold nucleic acid binding domain-containing protein compare
MMP_RS08645 +0.4 1.5 UPF0179 family protein compare
MMP_RS08890 +0.4 2.5 glycosyltransferase family 4 protein compare
MMP_RS03405 +0.4 2.0 RNA 3'-terminal phosphate cyclase compare
MMP_RS04225 +0.4 2.4 hypothetical protein compare
MMP_RS05955 +0.4 1.1 CoB--CoM heterodisulfide reductase subunit C compare
MMP_RS00705 +0.4 0.9 hypothetical protein compare
MMP_RS07605 +0.4 1.2 diadenylate cyclase compare
MMP_RS05940 +0.4 2.1 corrinoid protein compare
MMP_RS06930 +0.4 2.7 MBL fold metallo-hydrolase compare
MMP_RS06000 +0.4 1.6 divalent-cation tolerance protein CutA compare
MMP_RS03670 +0.4 1.6 DUF1890 domain-containing protein compare
MMP_RS03270 +0.4 2.3 ADP-ribosylglycohydrolase family protein compare
MMP_RS09045 +0.4 2.7 class III signal peptide-containing protein compare
MMP_RS05035 +0.4 2.4 hypothetical protein compare
MMP_RS00750 +0.4 0.8 fumarate hydratase compare
MMP_RS01925 +0.4 1.5 DUF1616 domain-containing protein compare
MMP_RS07875 +0.4 1.2 hypothetical protein compare
MMP_RS07090 +0.4 1.7 tRNA (adenine-N1)-methyltransferase compare
MMP_RS02550 +0.4 1.5 helix-turn-helix transcriptional regulator compare
MMP_RS03755 +0.4 1.9 MarR family transcriptional regulator compare
MMP_RS03495 +0.4 1.7 Na/Pi cotransporter family protein compare
MMP_RS04265 +0.4 1.0 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS00250 +0.4 2.5 Flp pilus assembly complex ATPase component TadA compare
MMP_RS01860 +0.4 1.1 hypothetical protein compare
MMP_RS09055 +0.4 0.4 CAP domain-containing protein compare
MMP_RS01975 +0.4 2.5 hypothetical protein compare
MMP_RS08275 +0.4 1.8 hypothetical protein compare
MMP_RS06140 +0.4 1.0 radical SAM protein compare
MMP_RS01140 +0.4 1.4 molybdate ABC transporter permease subunit compare
MMP_RS06365 +0.4 0.7 hypothetical protein compare
MMP_RS01900 +0.4 2.2 hypothetical protein compare
MMP_RS03430 +0.4 2.1 bile acid:sodium symporter family protein compare


Specific Phenotypes

For 6 genes in this experiment

For stress Sodium nitrate in Methanococcus maripaludis S2

For stress Sodium nitrate across organisms