Experiment set5IT066 for Sinorhizobium meliloti 1021

Compare to:

Defined media with L-Lysine

200 most important genes:

  gene name fitness t score description  
SMc02245 -7.4 -5.1 dihydroorotate dehydrogenase 2 compare
SMc00235 -7.2 -5.0 anthranilate phosphoribosyltransferase compare
SMc02766 -7.1 -12.7 tryptophan synthase subunit beta compare
SMc01726 -7.0 -4.7 acetylglutamate kinase compare
SMc03797 -6.9 -8.2 homoserine O-succinyltransferase compare
SMc02572 -6.8 -5.1 imidazole glycerol phosphate synthase subunit HisH compare
SMc00495 -6.8 -4.7 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
SMc04405 -6.8 -6.6 3-isopropylmalate dehydrogenase compare
SMc02767 -6.6 -6.5 N-(5'-phosphoribosyl)anthranilate isomerase compare
SMc02569 -6.6 -4.6 imidazole glycerol phosphate synthase subunit HisF compare
SMc00131 -6.5 -10.0 transcriptional regulator compare
SMc02123 -6.5 -3.5 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
SMc00640 -6.5 -6.3 phosphoserine aminotransferase compare
SMc02899 -6.4 -10.7 prephenate dehydratase compare
SMc02574 -6.3 -4.4 imidazoleglycerol-phosphate dehydratase compare
SMc02137 -6.3 -4.4 ornithine carbamoyltransferase compare
SMc04045 -6.3 -6.1 dihydroxy-acid dehydratase compare
SMc00917 -6.3 -4.3 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
SMc01801 -6.3 -4.1 N-acetylglutamylphosphate reductase (EC 1.2.1.38) (from data) compare
SMc00236 -6.2 -6.1 Indole-3-glycerol phosphate synthase compare
SMa1635 -6.2 -2.4 hypothetical protein compare
SMc01494 -6.2 -13.3 phosphoserine phosphatase compare
SMc01431 -6.2 -8.4 acetolactate synthase 3 catalytic subunit compare
SMc01843 -6.1 -8.4 5,10-methylenetetrahydrofolate reductase compare
SMc02217 -6.1 -4.2 O-succinylhomoserine sulfhydrylase compare
SMc02725 -6.1 -12.4 anthranilate synthase compare
SMc00090 -6.0 -8.2 sulfate adenylyltransferase compare
SMc02717 -6.0 -9.1 2-isopropylmalate synthase compare
SMc03823 -6.0 -11.4 isopropylmalate isomerase large subunit compare
SMc01361 -5.9 -5.8 dihydroorotase compare
SMc00615 -5.9 -11.0 phosphoribosylaminoimidazole synthetase compare
SMc00711 -5.8 -4.0 cyclohexadienyl dehydrogenase compare
SMc02707 -5.8 -5.1 hypothetical protein compare
SMc00918 -5.8 -9.7 ATP phosphoribosyltransferase regulatory subunit compare
SMc02166 -5.8 -11.7 dihydroorotase compare
SMc02765 -5.8 -12.5 tryptophan synthase subunit alpha compare
SMc00494 -5.7 -2.2 phosphoribosylformylglycinamidine synthase subunit PurS compare
SMc00092 -5.6 -11.5 phosphoadenosine phosphosulfate reductase compare
SMc00412 -5.6 -3.9 orotidine 5'-phosphate decarboxylase compare
SMc03112 -5.6 -15.7 B12-dependent methionine synthase compare
SMc02165 -5.5 -6.6 orotate phosphoribosyltransferase compare
SMc00293 -5.5 -11.7 homoserine dehydrogenase compare
SMc00488 -5.5 -19.1 phosphoribosylformylglycinamidine synthase II compare
SMc04002 -5.4 -7.2 phosphoribosylaminoimidazole carboxylase ATPase subunit compare
SMc00815 -5.4 -3.5 inosine 5'-monophosphate dehydrogenase compare
SMc01004 -5.4 -12.0 phosphoribosyl-AMP cyclohydrolase compare
SMc01054 -5.4 -5.2 required for sulfate utilization, putative electron source for sulfite reductase CysI (from data) compare
SMc04028 -5.3 -19.1 glutamate synthase compare
SMc03776 -5.2 -3.6 gamma-glutamyl kinase compare
SMc04026 -5.2 -9.9 glutamate synthase compare
SMc01360 -5.2 -3.6 aspartate carbamoyltransferase catalytic subunit compare
SMc02755 -5.1 -5.0 S-adenosyl-L-homocysteine hydrolase compare
SMc00614 -5.1 -7.8 phosphoribosylglycinamide formyltransferase compare
SM_b21176 -5.0 -4.9 phosphate uptake ABC transporter substrate-binding protein precursor compare
SMc02307 -5.0 -4.9 histidinol dehydrogenase compare
SMc02124 -4.8 -14.0 nitrite reductase compare
SMc00876 -4.7 -6.5 ATP-binding MRP protein compare
SM_b21175 -4.7 -4.9 phosphate uptake ABC transporter permease compare
SMc03826 -4.7 -3.2 argininosuccinate synthase compare
SMc00554 -4.7 -8.4 amidophosphoribosyltransferase compare
SMc02570 -4.7 -6.7 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
SMc03229 -4.6 -2.9 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase compare
SMc00993 -4.6 -10.1 phosphoribosylamine--glycine ligase compare
SMc00493 -4.5 -6.8 phosphoribosylformylglycinamidine synthase I compare
SMc00294 -4.5 -10.2 aminotransferase compare
SMc03070 -4.5 -9.4 glucose-6-phosphate 1-dehydrogenase compare
SM_b21174 -4.4 -6.5 phosphate uptake ABC transporter permease compare
SMc01845 -4.4 -2.8 transglycosylase transmembrane protein compare
SMc03777 -4.4 -8.4 gamma-glutamyl phosphate reductase compare
SMc04088 -4.4 -10.8 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase compare
SM_b21177 -4.4 -8.3 phosphate uptake ABC transporter ATP-binding protein compare
SMc01881 -4.3 -3.0 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
SMc00091 -4.2 -12.2 sulfate adenylyltransferase compare
SMc00641 -4.2 -7.5 D-3-phosphoglycerate dehydrogenase compare
SMc04001 -4.1 -1.6 phosphoribosylaminoimidazole carboxylase catalytic subunit protein compare
SMc02138 -4.1 -6.6 acetylornithine transaminase compare
SMc01430 -3.9 -5.8 acetolactate synthase 3 regulatory subunit compare
SM_b21181 -3.9 -8.2 glutaryl-CoA dehydrogenase compare
SMc03895 -3.9 -17.8 pyruvate carboxylase compare
SMc03763 -3.8 -2.6 cytosine-specific methyltransferase compare
SMc01441 -3.7 -7.0 membrane bound protease compare
SMc03978 -3.6 -2.5 transketolase compare
SMc00295 -3.6 -1.8 hypothetical protein compare
SMc01569 -3.5 -1.9 carbamoyl phosphate synthase small subunit compare
SMc01053 -3.4 -4.4 siroheme synthase compare
SMc01440 -3.4 -8.5 hydrolase serine protease transmembrane protein compare
SMc03795 -3.3 -1.7 isopropylmalate isomerase small subunit compare
SMc00017 -3.2 -1.7 homoserine kinase compare
SMc01770 -3.2 -1.5 serine hydroxymethyltransferase compare
SMc01880 -3.1 -2.1 pantoate--beta-alanine ligase compare
SMc00012 -3.1 -2.6 cytochrome C oxidase assembly protein compare
SMc01215 -3.1 -2.1 carbamoyl phosphate synthase large subunit compare
SMc02246 -3.1 -1.1 hypothetical protein compare
SMc03967 -2.9 -2.4 Holliday junction resolvase compare
SMc04346 -2.9 -4.1 ketol-acid reductoisomerase compare
SMc04296 -2.9 -1.5 cell division protein FtsZ compare
SMc04385 -2.8 -4.6 L-2-aminoadipate semialdehyde dehydrogenase (EC 1.2.1.31) (from data) compare
SMc01842 -2.8 -3.4 methyltransferase transcription regulator protein compare
SMc00414 -2.8 -9.1 hypothetical protein compare
SMc01850 -2.8 -4.1 hypothetical protein compare
SMc03924 -2.7 -11.4 glycogen synthase compare
SMc03981 -2.6 -4.3 phosphoglycerate kinase compare
SMc02683 -2.6 -3.0 hypothetical protein compare
SMc03979 -2.6 -2.2 glyceraldehyde-3-phosphate dehydrogenase compare
SM_b21182 -2.5 -7.8 hypothetical protein compare
SMc02147 -2.5 -7.8 phosphate regulon sensor histidine kinase transmembrane protein compare
SMc01315 -2.5 -2.0 hypothetical protein compare
SMc00361 -2.4 -4.7 hypothetical protein compare
SMc03068 -2.4 -9.9 phosphogluconate dehydratase compare
SMc02425 -2.4 -5.5 transcriptional regulator compare
SMc02685 -2.3 -3.9 hypothetical protein compare
SMc02140 -2.3 -2.3 phosphate regulon transcriptional regulatory protein compare
SMc02983 -2.2 -7.1 ornithine, DAP, or arginine decarboxylase compare
SMc02058 -2.2 -4.1 YAJC protein compare
SMc00838 -2.2 -4.8 hypothetical protein compare
SMc02835 -2.1 -8.4 glucokinase compare
SMc02724 -2.1 -3.3 hypothetical protein compare
SMc00914 -2.1 -4.3 oxidoreductase compare
SMa0789 -2.1 -4.7 GntR family transcriptional regulator compare
SMc02102 -2.1 -3.9 hypothetical protein compare
SMc02833 -2.0 -3.0 penicillin-insensitive murein endopeptidase compare
SMc02856 -1.9 -10.9 penicillin-binding protein compare
SMc03100 -1.9 -1.4 hypothetical protein compare
SMc03849 -1.9 -1.6 heme exporter C (cytochrome C-type biogenesis protein) transmembrane compare
SMc01438 -1.8 -7.2 protease precursor signal peptide protein compare
SMc03046 -1.8 -3.8 transcriptional regulator compare
SMc02641 -1.8 -5.3 UDP-glucose 6-dehydrogenase compare
SMc00492 -1.8 -1.3 hypothetical protein compare
SMc02234 -1.8 -4.1 hypothetical protein compare
SMc02141 -1.7 -4.1 phosphate transporter PhoU compare
SMc01208 -1.7 -3.8 peptidyl-prolyl cis-trans isomerase B protein compare
SMc02142 -1.7 -4.4 phosphate transporter ATP-binding protein compare
SMc04383 -1.7 -3.8 putative hydrolase, required for lysine catabolism (from data) compare
SMc04384 -1.7 -4.5 (R)-2-hydroxyglutarate dehydrogenase (EC 1.1.99.39) (from data) compare
SMc01206 -1.6 -2.0 queuine tRNA-ribosyltransferase compare
SMc01147 -1.6 -4.2 coproporphyrinogen III oxidase compare
SMa1095 -1.6 -1.2 hypothetical protein compare
SM_b20904 -1.6 -4.5 sugar uptake ABC transporter ATP-binding protein compare
SMc01124 -1.6 -6.0 PII uridylyl-transferase compare
SMa2215 -1.6 -3.4 GntR family transcriptional regulator compare
SMc02786 -1.5 -8.2 translocase transmembrane protein compare
SMc02510 -1.5 -0.9 ferric uptake regulation protein compare
SMc00286 -1.5 -2.2 hemolysin-type calcium-binding protein compare
SMc00709 -1.5 -3.7 hypothetical protein compare
SMc00987 -1.4 -2.3 hypothetical protein compare
SMc02115 -1.4 -1.5 hypothetical protein compare
SMc00579 -1.4 -4.9 dimethyladenosine transferase compare
SM_b20823 -1.4 -6.8 cell surface saccharide synthesis protein compare
SMc02753 -1.4 -1.8 PTS system transporter subunit IIA compare
SMc00691 -1.4 -3.6 site-specific tyrosine recombinase XerD compare
SMc02543 -1.3 -4.9 hypothetical protein compare
SMc01364 -1.3 -1.1 DNA topoisomerase I compare
SM_b20563 -1.3 -3.0 hypothetical protein compare
SMc01368 -1.3 -4.3 transport transmembrane protein compare
SMc00802 -1.3 -1.1 hypothetical protein compare
SM_b20773 -1.3 -3.7 GntR family transcriptional regulator compare
SMc01097 -1.3 -2.7 hypothetical protein compare
SM_b20903 -1.2 -6.9 sugar uptake ABC transporter permease compare
SMc00405 -1.2 -5.7 hypothetical protein compare
SMc00296 -1.2 -6.1 POLY3-hydroxybutyrate polymerase compare
SMc03993 -1.2 -3.2 hypothetical protein compare
SMc00854 -1.2 -1.2 hypothetical protein compare
SMc01342 -1.2 -3.9 hypothetical protein compare
SMc01187 -1.2 -1.6 rare lipoprotein A compare
SMc00450 -1.1 -1.7 protoheme IX farnesyltransferase compare
SMc04213 -1.1 -1.9 diacylglycerol kinase compare
SMc02909 -1.1 -1.2 transglycosylase transmembrane protein compare
SMc00514 -1.1 -2.3 monooxygenase compare
SMc02144 -1.1 -4.3 phosphate ABC transporter permease compare
SMc00073 -1.1 -1.9 hypothetical protein compare
SMc01183 -1.1 -1.5 LexA repressor compare
SMc01568 -1.1 -1.8 hypothetical protein compare
SMc02451 -1.1 -1.4 hypothetical protein compare
SMc02434 -1.1 -2.7 hypothetical protein compare
SMc02985 -1.1 -6.3 hypothetical protein compare
SMc04000 -1.1 -1.0 hypothetical protein compare
SMc00288 -1.1 -5.2 signal peptide protein compare
SM_b20902 -1.1 -6.0 sugar uptake ABC transporter substrate-binding protein precursor compare
SMa1002 -1.0 -1.7 hypothetical protein compare
SM_b20258 -1.0 -3.6 transcriptional regulator compare
SMc02232 -1.0 -2.0 hypothetical protein compare
SMc00150 -1.0 -7.9 hypothetical protein compare
SMc03127 -1.0 -1.6 ABC transporter permease compare
SMc02850 -1.0 -2.7 DNA polymerase I compare
SMc01091 -1.0 -1.8 hypothetical protein compare
SMc01207 -1.0 -1.6 S-adenosylmethionine--tRNA ribosyltransferase-isomerase compare
SMc03069 -1.0 -1.8 6-phosphogluconolactonase compare
SMc01495 -1.0 -2.0 transcriptional regulator compare
SMa0508 -1.0 -3.4 ABC transporter ATP-binding protein compare
SMc02450 -0.9 -1.9 bifunctional ornithine acetyltransferase/N-acetylglutamate synthase compare
SMc02114 -0.9 -2.6 hypothetical protein compare
SM_b20302 -0.9 -1.7 hypothetical protein compare
SMc04348 -0.9 -1.0 transcriptional regulator compare
SMc02484 -0.9 -2.7 amino acid efflux transmembrane protein compare
SMa1770 -0.9 -1.1 hypothetical protein compare
SMc04243 -0.9 -4.6 high-affinity zinc uptake system membrane ABC transporter protein compare
SMc03008 -0.9 -1.1 chemotaxis protein compare
SMc02640 -0.9 -3.1 UDP-glucuronic acid epimerase compare
SMc02861 -0.9 -1.5 phosphate transporter compare
SMc03899 -0.9 -1.1 hypothetical protein compare


Specific Phenotypes

None in this experiment

For Sinorhizobium meliloti 1021 in nutrient experiments

For nutrient L-Lysine across organisms