Experiment set5IT065 for Sinorhizobium meliloti 1021

Compare to:

Defined media with L-Lysine

200 most important genes:

  gene name fitness t score description  
SMc02245 -7.4 -5.1 dihydroorotate dehydrogenase 2 compare
SMc01726 -6.9 -4.7 acetylglutamate kinase compare
SMc00235 -6.8 -6.7 anthranilate phosphoribosyltransferase compare
SMc01843 -6.8 -8.1 5,10-methylenetetrahydrofolate reductase compare
SMc02899 -6.8 -9.3 prephenate dehydratase compare
SMc02569 -6.7 -4.6 imidazole glycerol phosphate synthase subunit HisF compare
SMc04405 -6.7 -6.5 3-isopropylmalate dehydrogenase compare
SMc02766 -6.7 -14.3 tryptophan synthase subunit beta compare
SMc03797 -6.6 -10.1 homoserine O-succinyltransferase compare
SMc01494 -6.5 -9.9 phosphoserine phosphatase compare
SMc00640 -6.5 -6.4 phosphoserine aminotransferase compare
SMc01801 -6.4 -4.2 N-acetylglutamylphosphate reductase (EC 1.2.1.38) (from data) compare
SMc00236 -6.4 -5.4 Indole-3-glycerol phosphate synthase compare
SMc00917 -6.4 -4.4 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
SMc02767 -6.3 -8.6 N-(5'-phosphoribosyl)anthranilate isomerase compare
SMc02725 -6.3 -11.3 anthranilate synthase compare
SMa1635 -6.2 -2.4 hypothetical protein compare
SMc04002 -6.1 -8.4 phosphoribosylaminoimidazole carboxylase ATPase subunit compare
SMc02574 -6.0 -5.9 imidazoleglycerol-phosphate dehydratase compare
SMc02123 -6.0 -4.0 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
SMc04028 -6.0 -16.4 glutamate synthase compare
SMc01431 -6.0 -12.8 acetolactate synthase 3 catalytic subunit compare
SMc00711 -6.0 -4.1 cyclohexadienyl dehydrogenase compare
SMc02717 -6.0 -10.7 2-isopropylmalate synthase compare
SMc00918 -5.9 -9.9 ATP phosphoribosyltransferase regulatory subunit compare
SMc00131 -5.9 -13.8 transcriptional regulator compare
SMc03112 -5.9 -16.1 B12-dependent methionine synthase compare
SMc00293 -5.9 -12.5 homoserine dehydrogenase compare
SMc03823 -5.8 -11.8 isopropylmalate isomerase large subunit compare
SMc00554 -5.8 -4.0 amidophosphoribosyltransferase compare
SMc02572 -5.8 -5.0 imidazole glycerol phosphate synthase subunit HisH compare
SMc02137 -5.8 -5.6 ornithine carbamoyltransferase compare
SMc00494 -5.7 -2.2 phosphoribosylformylglycinamidine synthase subunit PurS compare
SMc04026 -5.7 -9.5 glutamate synthase compare
SMc04045 -5.7 -9.4 dihydroxy-acid dehydratase compare
SMc02217 -5.6 -6.7 O-succinylhomoserine sulfhydrylase compare
SMc01361 -5.6 -6.7 dihydroorotase compare
SM_b21174 -5.6 -5.1 phosphate uptake ABC transporter permease compare
SMc00488 -5.6 -18.7 phosphoribosylformylglycinamidine synthase II compare
SMc00993 -5.6 -9.3 phosphoribosylamine--glycine ligase compare
SMc01054 -5.5 -5.4 required for sulfate utilization, putative electron source for sulfite reductase CysI (from data) compare
SMc00493 -5.5 -5.4 phosphoribosylformylglycinamidine synthase I compare
SMc02765 -5.5 -12.4 tryptophan synthase subunit alpha compare
SMc01004 -5.4 -10.2 phosphoribosyl-AMP cyclohydrolase compare
SMc00090 -5.4 -7.4 sulfate adenylyltransferase compare
SMc00412 -5.4 -5.2 orotidine 5'-phosphate decarboxylase compare
SM_b21175 -5.3 -5.4 phosphate uptake ABC transporter permease compare
SMc00092 -5.3 -13.3 phosphoadenosine phosphosulfate reductase compare
SMc01360 -5.3 -3.6 aspartate carbamoyltransferase catalytic subunit compare
SMc03777 -5.3 -7.2 gamma-glutamyl phosphate reductase compare
SMc00615 -5.2 -9.7 phosphoribosylaminoimidazole synthetase compare
SM_b21176 -5.2 -5.0 phosphate uptake ABC transporter substrate-binding protein precursor compare
SMc02124 -5.1 -14.0 nitrite reductase compare
SMc02165 -5.1 -9.7 orotate phosphoribosyltransferase compare
SMc02166 -4.9 -14.2 dihydroorotase compare
SMc02755 -4.9 -6.7 S-adenosyl-L-homocysteine hydrolase compare
SM_b21177 -4.8 -8.0 phosphate uptake ABC transporter ATP-binding protein compare
SMc00091 -4.8 -12.7 sulfate adenylyltransferase compare
SMc03826 -4.8 -3.3 argininosuccinate synthase compare
SMc00614 -4.8 -6.9 phosphoribosylglycinamide formyltransferase compare
SMc00495 -4.8 -6.5 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
SMc03229 -4.7 -3.0 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase compare
SMc03776 -4.7 -4.5 gamma-glutamyl kinase compare
SMc02138 -4.4 -5.8 acetylornithine transaminase compare
SMc00641 -4.4 -7.3 D-3-phosphoglycerate dehydrogenase compare
SMc00815 -4.3 -2.9 inosine 5'-monophosphate dehydrogenase compare
SMc03070 -4.3 -8.2 glucose-6-phosphate 1-dehydrogenase compare
SMc04088 -4.3 -11.1 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase compare
SMc02307 -4.3 -7.7 histidinol dehydrogenase compare
SMc04001 -4.3 -1.6 phosphoribosylaminoimidazole carboxylase catalytic subunit protein compare
SMc03895 -4.2 -20.3 pyruvate carboxylase compare
SMc00294 -4.1 -11.8 aminotransferase compare
SMc00876 -4.0 -7.5 ATP-binding MRP protein compare
SMc03763 -3.9 -2.7 cytosine-specific methyltransferase compare
SMc01053 -3.8 -4.9 siroheme synthase compare
SMc03978 -3.8 -2.6 transketolase compare
SMc01430 -3.7 -6.7 acetolactate synthase 3 regulatory subunit compare
SMc02570 -3.6 -4.0 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
SMc01569 -3.6 -1.9 carbamoyl phosphate synthase small subunit compare
SMc03981 -3.6 -5.0 phosphoglycerate kinase compare
SMc04346 -3.4 -4.7 ketol-acid reductoisomerase compare
SMc02707 -3.3 -4.2 hypothetical protein compare
SMc01770 -3.3 -1.5 serine hydroxymethyltransferase compare
SMc00017 -3.3 -1.7 homoserine kinase compare
SMc01440 -3.3 -6.4 hydrolase serine protease transmembrane protein compare
SMc01880 -3.2 -2.2 pantoate--beta-alanine ligase compare
SMc01215 -3.2 -2.2 carbamoyl phosphate synthase large subunit compare
SMc01441 -3.1 -6.6 membrane bound protease compare
SMc00295 -3.1 -2.3 hypothetical protein compare
SMc02246 -3.1 -1.1 hypothetical protein compare
SMc02425 -3.1 -6.6 transcriptional regulator compare
SMc03979 -3.0 -2.8 glyceraldehyde-3-phosphate dehydrogenase compare
SM_b21181 -2.9 -8.9 glutaryl-CoA dehydrogenase compare
SM_b21182 -2.9 -8.5 hypothetical protein compare
SMc02058 -2.8 -4.7 YAJC protein compare
SMc03795 -2.8 -2.1 isopropylmalate isomerase small subunit compare
SMc01881 -2.7 -3.6 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
SMc01187 -2.7 -3.1 rare lipoprotein A compare
SMc03068 -2.7 -11.4 phosphogluconate dehydratase compare
SMc00414 -2.6 -10.3 hypothetical protein compare
SMc02983 -2.6 -7.8 ornithine, DAP, or arginine decarboxylase compare
SMc01206 -2.6 -3.4 queuine tRNA-ribosyltransferase compare
SMc04385 -2.6 -4.6 L-2-aminoadipate semialdehyde dehydrogenase (EC 1.2.1.31) (from data) compare
SMc02683 -2.6 -3.7 hypothetical protein compare
SMc02147 -2.5 -7.9 phosphate regulon sensor histidine kinase transmembrane protein compare
SMc02833 -2.5 -3.6 penicillin-insensitive murein endopeptidase compare
SMc02115 -2.4 -2.0 hypothetical protein compare
SMc00619 -2.4 -3.8 hypothetical protein compare
SMc00450 -2.4 -4.4 protoheme IX farnesyltransferase compare
SMc02909 -2.4 -3.5 transglycosylase transmembrane protein compare
SMc02685 -2.4 -4.7 hypothetical protein compare
SMc01147 -2.3 -4.6 coproporphyrinogen III oxidase compare
SMc02582 -2.2 -4.3 hypothetical protein compare
SMc02641 -2.2 -6.0 UDP-glucose 6-dehydrogenase compare
SMc02835 -2.2 -8.0 glucokinase compare
SMc00088 -2.2 -2.3 hypothetical protein compare
SMc03924 -2.1 -9.4 glycogen synthase compare
SMc02753 -2.1 -2.4 PTS system transporter subunit IIA compare
SMc00361 -2.1 -4.5 hypothetical protein compare
SMc01850 -2.0 -2.4 hypothetical protein compare
SMc02102 -2.0 -5.4 hypothetical protein compare
SMc04213 -1.9 -2.6 diacylglycerol kinase compare
SMc01842 -1.9 -1.8 methyltransferase transcription regulator protein compare
SMc03967 -1.9 -2.0 Holliday junction resolvase compare
SMc00838 -1.9 -5.0 hypothetical protein compare
SMc00914 -1.9 -5.9 oxidoreductase compare
SMc04383 -1.8 -4.9 putative hydrolase, required for lysine catabolism (from data) compare
SMc00709 -1.8 -3.0 hypothetical protein compare
SMc01364 -1.8 -1.4 DNA topoisomerase I compare
SMc02886 -1.7 -3.4 signal peptide protein compare
SMc01208 -1.7 -3.1 peptidyl-prolyl cis-trans isomerase B protein compare
SMc00712 -1.6 -2.6 hypothetical protein compare
SMc02856 -1.6 -9.1 penicillin-binding protein compare
SMc00334 -1.6 -2.1 cytidylate kinase compare
SMc01579 -1.6 -1.7 hypothetical protein compare
SMc02451 -1.6 -2.1 hypothetical protein compare
SMc02724 -1.6 -3.8 hypothetical protein compare
SMc03849 -1.6 -2.0 heme exporter C (cytochrome C-type biogenesis protein) transmembrane compare
SMc02434 -1.6 -4.1 hypothetical protein compare
SMc01495 -1.6 -5.0 transcriptional regulator compare
SMc02985 -1.6 -7.9 hypothetical protein compare
SMc01124 -1.6 -5.9 PII uridylyl-transferase compare
SMc04330 -1.5 -3.2 trimethylamine methyltransferase compare
SMc00012 -1.5 -2.0 cytochrome C oxidase assembly protein compare
SMc02142 -1.5 -6.2 phosphate transporter ATP-binding protein compare
SMa0789 -1.5 -3.8 GntR family transcriptional regulator compare
SMc00288 -1.5 -6.7 signal peptide protein compare
SMc00987 -1.5 -3.2 hypothetical protein compare
SMc02505 -1.5 -1.2 hypothetical protein compare
SM_b20903 -1.4 -6.8 sugar uptake ABC transporter permease compare
SMc02140 -1.4 -1.7 phosphate regulon transcriptional regulatory protein compare
SMc04384 -1.4 -4.9 (R)-2-hydroxyglutarate dehydrogenase (EC 1.1.99.39) (from data) compare
SMc01183 -1.4 -1.6 LexA repressor compare
SMc02858 -1.4 -1.0 chaperone protein DnaJ compare
SMc03242 -1.4 -2.9 GTP-binding protein compare
SMc03993 -1.4 -6.8 hypothetical protein compare
SMc01845 -1.4 -2.1 transglycosylase transmembrane protein compare
SM_b20823 -1.4 -7.5 cell surface saccharide synthesis protein compare
SMc02495 -1.4 -1.7 translaldolase compare
SMa1095 -1.3 -1.1 hypothetical protein compare
SMc04296 -1.3 -1.4 cell division protein FtsZ compare
SMc01438 -1.3 -4.5 protease precursor signal peptide protein compare
SMc01342 -1.3 -4.3 hypothetical protein compare
SMc02363 -1.3 -3.5 cytochrome C-type biogenesis transmembrane protein compare
SMc01315 -1.3 -1.5 hypothetical protein compare
SMc00073 -1.3 -1.8 hypothetical protein compare
SMc02485 -1.3 -2.0 signal peptide protein compare
SMc00296 -1.3 -7.5 POLY3-hydroxybutyrate polymerase compare
SMc03069 -1.3 -1.6 6-phosphogluconolactonase compare
SMc03850 -1.2 -1.3 heme exporter D (cytochrome C-type biogenesis protein) transmembrane compare
SMc03100 -1.2 -1.2 hypothetical protein compare
SMc02308 -1.2 -4.9 hypothetical protein compare
SMc02450 -1.2 -1.5 bifunctional ornithine acetyltransferase/N-acetylglutamate synthase compare
SMc02232 -1.2 -2.4 hypothetical protein compare
SM_b20258 -1.2 -3.9 transcriptional regulator compare
SMc00352 -1.2 -2.3 acetyltransferase compare
SMc01259 -1.2 -2.9 hypothetical protein compare
SMc00060 -1.2 -5.3 hypothetical protein compare
SMc01568 -1.2 -1.7 hypothetical protein compare
SM_b20148 -1.2 -3.3 transcriptional regulator compare
SMc01097 -1.2 -4.2 hypothetical protein compare
SM_b20902 -1.2 -6.7 sugar uptake ABC transporter substrate-binding protein precursor compare
SM_b20773 -1.2 -3.5 GntR family transcriptional regulator compare
SMc02510 -1.2 -0.8 ferric uptake regulation protein compare
SMc03046 -1.2 -3.9 transcriptional regulator compare
SMc02144 -1.2 -3.3 phosphate ABC transporter permease compare
SMc01368 -1.2 -3.1 transport transmembrane protein compare
SMc03878 -1.1 -2.7 acetoacetyl-CoA reductase compare
SMc00405 -1.1 -6.9 hypothetical protein compare
SMc04000 -1.1 -1.0 hypothetical protein compare
SMc02786 -1.1 -5.5 translocase transmembrane protein compare
SM_b20563 -1.1 -2.0 hypothetical protein compare
SMc01260 -1.1 -3.4 transcriptional regulator compare
SMc00963 -1.1 -2.6 hypothetical protein compare
SMc04052 -1.1 -1.4 transcriptional regulator compare
SMc01404 -1.1 -3.0 aspartate racemase compare
SMc00580 -1.1 -3.2 4-hydroxythreonine-4-phosphate dehydrogenase compare
SMc04882 -1.1 -3.1 transcriptional regulator compare
SMc01505 -1.1 -1.5 hypothetical protein compare
SM_b21687 -1.0 -2.3 hypothetical protein compare


Specific Phenotypes

None in this experiment

For Sinorhizobium meliloti 1021 in nutrient experiments

For nutrient L-Lysine across organisms