Experiment set5IT065 for Klebsiella michiganensis M5al

Compare to:

Inosine carbon source

200 most important genes:

  gene name fitness t score description  
BWI76_RS00805 -7.7 -5.1 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS18950 -7.5 -4.9 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS04160 -7.5 -7.3 phosphoserine phosphatase compare
BWI76_RS18925 -7.4 -5.0 histidinol dehydrogenase compare
BWI76_RS04470 -7.4 -5.1 carbamoyl phosphate synthase large subunit compare
BWI76_RS17290 -7.3 -5.0 formyltetrahydrofolate deformylase compare
BWI76_RS05840 -6.9 -4.7 glutamate 5-kinase compare
BWI76_RS04465 -6.6 -4.6 carbamoyl-phosphate synthase small subunit compare
BWI76_RS18920 -6.6 -4.4 ATP phosphoribosyltransferase compare
BWI76_RS04145 -6.6 -3.7 purine-nucleoside phosphorylase compare
BWI76_RS18940 -6.5 -6.4 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS23920 -6.5 -4.4 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS11965 -6.4 -4.8 orotidine-5'-phosphate decarboxylase compare
BWI76_RS05835 -6.2 -4.1 gamma-glutamyl-phosphate reductase compare
BWI76_RS09760 -6.0 -6.8 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS09755 -6.0 -8.3 phosphoserine transaminase compare
BWI76_RS24285 -5.8 -8.0 cystathionine beta-lyase compare
BWI76_RS23360 -5.8 -3.6 diaminopimelate decarboxylase compare
BWI76_RS04250 -5.8 -7.9 homoserine kinase compare
BWI76_RS00855 -5.7 -9.0 argininosuccinate lyase compare
BWI76_RS11850 -5.7 -7.1 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS26085 -5.6 -3.3 3-dehydroquinate synthase compare
BWI76_RS00980 -5.5 -11.3 PLP-dependent threonine dehydratase compare
BWI76_RS18935 -5.5 -9.0 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS00850 -5.3 -7.3 acetylglutamate kinase compare
BWI76_RS18930 -5.3 -2.6 histidinol-phosphate transaminase compare
BWI76_RS21475 -5.3 -4.9 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS11860 -5.2 -8.3 anthranilate synthase component I compare
BWI76_RS27385 -5.0 -6.8 orotate phosphoribosyltransferase compare
BWI76_RS04245 -4.7 -14.3 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS23220 -4.7 -7.1 amino-acid N-acetyltransferase compare
BWI76_RS22760 -4.7 -8.4 sulfite reductase subunit beta compare
BWI76_RS05005 -4.7 -2.8 polynucleotide adenylyltransferase compare
BWI76_RS00835 -4.7 -13.3 phosphoenolpyruvate carboxylase compare
BWI76_RS08385 -4.5 -4.5 citrate (Si)-synthase compare
BWI76_RS18955 -4.5 -4.7 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS21465 -4.5 -5.8 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS22755 -4.4 -7.7 phosphoadenosine phosphosulfate reductase compare
BWI76_RS11845 -4.3 -1.7 tryptophan synthase subunit beta compare
BWI76_RS04240 -4.3 -1.7 thr operon leader peptide compare
BWI76_RS00990 -4.3 -7.9 ketol-acid reductoisomerase compare
BWI76_RS00845 -4.3 -8.5 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS16520 -4.2 -5.3 Bcr/CflA family multidrug efflux MFS transporter conserved
BWI76_RS00785 -4.2 -7.8 cystathionine gamma-synthase compare
BWI76_RS22765 -4.1 -9.7 sulfite reductase subunit alpha compare
BWI76_RS10990 -4.1 -4.1 dihydroorotase compare
BWI76_RS26460 -4.1 -5.4 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS11840 -4.0 -5.1 tryptophan synthase subunit alpha compare
BWI76_RS01655 -4.0 -5.7 homoserine O-succinyltransferase compare
BWI76_RS00975 -3.9 -7.4 dihydroxy-acid dehydratase compare
BWI76_RS03010 -3.9 -6.5 ornithine carbamoyltransferase compare
BWI76_RS04670 -3.9 -8.2 3-isopropylmalate dehydratase large subunit compare
BWI76_RS11855 -3.9 -5.0 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS04665 -3.8 -17.0 3-isopropylmalate dehydratase small subunit compare
BWI76_RS04645 -3.8 -5.4 3-dehydroquinase compare
BWI76_RS09660 -3.7 -2.5 DNA translocase FtsK compare
BWI76_RS20435 -3.7 -1.8 chorismate synthase compare
BWI76_RS02995 -3.7 -7.8 aspartate carbamoyltransferase compare
BWI76_RS25960 -3.6 -6.0 NUDIX hydrolase compare
BWI76_RS00400 -3.6 -2.0 glutamine synthetase compare
BWI76_RS09910 -3.5 -14.1 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS15660 -3.5 -1.2 hypothetical protein compare
BWI76_RS04255 -3.5 -5.9 threonine synthase compare
BWI76_RS04675 -3.5 -4.1 3-isopropylmalate dehydrogenase compare
BWI76_RS20995 -3.5 -6.2 RNA degradosome polyphosphate kinase compare
BWI76_RS00985 -3.4 -7.6 transcriptional regulator IlvY compare
BWI76_RS20160 -3.4 -4.3 NADH-quinone oxidoreductase subunit H compare
BWI76_RS04680 -3.3 -13.1 2-isopropylmalate synthase compare
BWI76_RS06185 -3.2 -5.7 shikimate kinase II compare
BWI76_RS27390 -3.2 -3.8 ribonuclease PH compare
BWI76_RS26455 -3.2 -3.3 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
BWI76_RS25115 -3.1 -6.7 argininosuccinate synthase compare
BWI76_RS09730 -3.0 -2.0 pyruvate formate lyase 1-activating protein compare
BWI76_RS12145 -3.0 -3.3 hypothetical protein compare
BWI76_RS04685 -3.0 -8.3 putative leucine operon leader peptide compare
BWI76_RS23240 -3.0 -4.5 exonuclease V subunit gamma compare
BWI76_RS04270 -2.9 -5.1 transaldolase compare
BWI76_RS20145 -2.9 -1.9 NADH-quinone oxidoreductase subunit K compare
BWI76_RS23365 -2.8 -4.1 LysR family transcriptional regulator compare
BWI76_RS02735 -2.8 -5.4 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS20270 -2.7 -7.3 hypothetical protein compare
BWI76_RS18885 -2.6 -3.1 nitrogen fixation regulatory protein compare
BWI76_RS27430 -2.6 -1.8 (p)ppGpp synthetase compare
BWI76_RS27915 -2.6 -3.0 YceK/YidQ family lipoprotein compare
BWI76_RS09195 -2.6 -1.8 N-acetyltransferase compare
BWI76_RS22240 -2.6 -6.3 transcriptional regulator compare
BWI76_RS05880 -2.5 -1.9 AraC-type DNA-binding domain-containing protein compare
BWI76_RS04140 -2.5 -3.1 phosphopentomutase compare
BWI76_RS01210 -2.5 -2.5 tyrosine recombinase XerC compare
BWI76_RS07725 -2.4 -1.6 iron-enterobactin transporter permease compare
BWI76_RS06730 -2.3 -3.2 lac repressor compare
BWI76_RS02530 -2.3 -2.3 tRNA dimethylallyltransferase compare
BWI76_RS04705 -2.3 -5.2 DNA-binding transcriptional regulator FruR compare
BWI76_RS21580 -2.3 -2.0 SsrA-binding protein compare
BWI76_RS00965 -2.3 -1.5 acetolactate synthase 2 small subunit compare
BWI76_RS24900 -2.2 -2.4 DeoR family transcriptional regulator compare
BWI76_RS25645 -2.2 -7.6 shikimate dehydrogenase compare
BWI76_RS22420 -2.2 -2.1 LacI family transcriptional regulator compare
BWI76_RS26620 -2.2 -1.4 Fe-S biogenesis protein NfuA compare
BWI76_RS01185 -2.2 -2.8 adenylate cyclase compare
BWI76_RS20650 -2.1 -2.8 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS16515 -2.1 -2.0 LysR family transcriptional regulator compare
BWI76_RS20150 -2.1 -2.1 NADH:ubiquinone oxidoreductase subunit J compare
BWI76_RS23230 -2.0 -3.8 exodeoxyribonuclease V subunit beta compare
BWI76_RS01385 -2.0 -3.3 potassium transporter compare
BWI76_RS05015 -2.0 -1.5 transcriptional regulator compare
BWI76_RS17070 -2.0 -3.0 phosphoenolpyruvate synthase regulatory protein compare
BWI76_RS09530 -2.0 -1.3 hypothetical protein compare
BWI76_RS26570 -2.0 -2.2 anion permease compare
BWI76_RS20440 -2.0 -2.0 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS01885 -1.9 -1.6 CsbD family protein compare
BWI76_RS03415 -1.9 -4.7 LacI family transcriptional regulator compare
BWI76_RS26175 -1.9 -2.6 DeoR/GlpR family transcriptional regulator compare
BWI76_RS15825 -1.9 -2.9 hypothetical protein compare
BWI76_RS26150 -1.8 -2.3 molecular chaperone Hsp33 compare
BWI76_RS05200 -1.8 -2.5 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS22690 -1.8 -1.6 adenylyl-sulfate kinase compare
BWI76_RS06735 -1.8 -2.0 50S ribosomal protein L31 compare
BWI76_RS15350 -1.8 -1.4 hypothetical protein compare
BWI76_RS00355 -1.8 -1.8 DNA polymerase I compare
BWI76_RS21165 -1.8 -1.9 Fe-S cluster assembly transcriptional regulator IscR compare
BWI76_RS00345 -1.8 -2.9 protein disulfide oxidoreductase DsbA compare
BWI76_RS15060 -1.8 -3.6 MarR family transcriptional regulator compare
BWI76_RS09615 -1.7 -2.7 ATP-dependent Clp protease ATP-binding subunit ClpA compare
BWI76_RS15760 -1.7 -1.8 hypothetical protein compare
BWI76_RS20540 -1.7 -5.3 NupC/NupG family nucleoside CNT transporter conserved
BWI76_RS16955 -1.7 -1.6 hypothetical protein compare
BWI76_RS10060 -1.7 -1.3 acylphosphatase compare
BWI76_RS14775 -1.7 -1.7 creatinine amidohydrolase compare
BWI76_RS01630 -1.7 -1.2 16S ribosomal RNA compare
BWI76_RS20785 -1.7 -1.2 ethanolamine utilization protein EutJ compare
BWI76_RS21690 -1.6 -2.2 hypothetical protein compare
BWI76_RS27475 -1.6 -5.4 regulatory protein GntR family protein compare
BWI76_RS01115 -1.6 -3.4 dTDP-4-amino-4,6-dideoxygalactose transaminase compare
BWI76_RS20155 -1.6 -1.5 NADH-quinone oxidoreductase subunit I compare
BWI76_RS23480 -1.5 -8.1 EAL domain-containing protein compare
BWI76_RS08535 -1.5 -1.2 translocation protein TolB compare
BWI76_RS07865 -1.5 -2.1 methylthioribulose 1-phosphate dehydratase compare
BWI76_RS26055 -1.5 -4.1 siroheme synthase compare
BWI76_RS03080 -1.4 -2.1 (Fe-S)-cluster assembly protein compare
BWI76_RS08520 -1.4 -1.3 colicin transporter TolQ compare
BWI76_RS20965 -1.4 -2.0 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS25425 -1.4 -1.7 arginine repressor compare
BWI76_RS15830 -1.4 -2.3 hypothetical protein compare
BWI76_RS20380 -1.4 -1.1 tRNA pseudouridine(38-40) synthase TruA compare
BWI76_RS06765 -1.4 -1.6 transcriptional regulator compare
BWI76_RS09645 -1.3 -1.1 thioredoxin-disulfide reductase compare
BWI76_RS05120 -1.3 -5.0 bifunctional glycosyl transferase/transpeptidase compare
BWI76_RS01070 -1.3 -4.4 thiol reductase thioredoxin compare
BWI76_RS20430 -1.3 -1.7 penicillin-insensitive murein endopeptidase compare
BWI76_RS04510 -1.3 -1.0 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) compare
BWI76_RS26395 -1.3 -2.9 cell division protein FtsE compare
BWI76_RS15810 -1.3 -4.1 hypothetical protein compare
BWI76_RS07675 -1.3 -3.8 DeoR family transcriptional regulator compare
BWI76_RS01615 -1.3 -4.9 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS20390 -1.3 -1.8 erythronate-4-phosphate dehydrogenase compare
BWI76_RS13160 -1.3 -1.8 azoreductase compare
BWI76_RS20795 -1.3 -0.9 ethanolamine catabolic microcompartment shell protein EutN compare
BWI76_RS09190 -1.2 -2.2 hypothetical protein compare
BWI76_RS17110 -1.2 -1.2 vitamin B12 ABC transporter permease BtuC compare
BWI76_RS17720 -1.2 -1.2 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS16315 -1.2 -1.3 SirA-like protein compare
BWI76_RS11395 -1.2 -2.5 RNA polymerase sigma factor FecI compare
BWI76_RS08405 -1.2 -2.2 succinate dehydrogenase flavoprotein subunit compare
BWI76_RS27825 -1.2 -2.9 hypothetical protein compare
BWI76_RS08395 -1.2 -1.6 succinate dehydrogenase cytochrome b556 large subunit compare
BWI76_RS08205 -1.2 -3.7 DNA-binding transcriptional dual regulator NagC compare
BWI76_RS27170 -1.2 -3.8 MltR family transcriptional regulator compare
BWI76_RS08525 -1.2 -2.8 colicin transporter compare
BWI76_RS15955 -1.2 -5.8 transcriptional regulator compare
BWI76_RS20170 -1.2 -2.4 NADH-quinone oxidoreductase subunit F compare
BWI76_RS20180 -1.1 -3.2 NADH-quinone oxidoreductase subunit C/D compare
BWI76_RS27455 -1.1 -2.2 DUF805 domain-containing protein compare
BWI76_RS02610 -1.1 -3.0 transcriptional regulator compare
BWI76_RS17400 -1.1 -1.0 transporter compare
BWI76_RS26270 -1.1 -1.8 N-acetyltransferase compare
BWI76_RS22695 -1.1 -3.7 sulfate adenylyltransferase compare
BWI76_RS23810 -1.1 -1.4 bifunctional protein-disulfide isomerase/oxidoreductase DsbC compare
BWI76_RS12815 -1.1 -2.7 transcriptional regulator FeaR compare
BWI76_RS03225 -1.1 -4.3 transcriptional regulator compare
BWI76_RS26190 -1.1 -2.6 glycerol-3-phosphate dehydrogenase compare
BWI76_RS15680 -1.1 -2.7 hypothetical protein compare
BWI76_RS24850 -1.1 -4.1 DeoR family transcriptional regulator compare
BWI76_RS13275 -1.1 -1.4 hypothetical protein compare
BWI76_RS15665 -1.0 -2.4 hypothetical protein compare
BWI76_RS15835 -1.0 -0.7 hypothetical protein compare
BWI76_RS14670 -1.0 -1.4 hypothetical protein compare
BWI76_RS07785 -1.0 -1.7 transcriptional regulator compare
BWI76_RS01680 -1.0 -3.6 transcriptional regulator IclR compare
BWI76_RS20800 -1.0 -2.0 carboxysome shell protein compare
BWI76_RS15570 -1.0 -2.5 phage antirepressor Ant compare
BWI76_RS27075 -1.0 -3.6 IclR family transcriptional regulator compare
BWI76_RS15635 -1.0 -2.9 hypothetical protein compare
BWI76_RS15975 -1.0 -0.8 hypothetical protein compare
BWI76_RS05160 -1.0 -1.6 hypothetical protein compare
BWI76_RS00795 -1.0 -1.7 carboxymuconolactone decarboxylase compare
BWI76_RS16240 -1.0 -1.3 anti-adapter protein IraM compare
BWI76_RS05680 -1.0 -1.6 LacI family transcriptional regulator compare
BWI76_RS08530 -1.0 -1.8 protein TolA compare
BWI76_RS20640 -1.0 -2.2 cysteine synthase A compare


Specific Phenotypes

For 3 genes in this experiment

For carbon source Inosine in Klebsiella michiganensis M5al

For carbon source Inosine across organisms