Experiment set5IT065 for Klebsiella michiganensis M5al

Compare to:

Inosine carbon source

200 most detrimental genes:

  gene name fitness t score description  
BWI76_RS00765 +4.8 21.4 DNA-binding transcriptional regulator CytR conserved
BWI76_RS09150 +4.5 29.6 DNA-binding transcriptional repressor DeoR compare
BWI76_RS17975 +1.8 5.3 tail-specific protease compare
BWI76_RS20900 +1.7 2.8 outer membrane protein assembly factor BamC compare
BWI76_RS25060 +1.6 6.0 lipoprotein NlpI compare
BWI76_RS20230 +1.6 2.3 hypothetical protein compare
BWI76_RS20360 +1.5 2.0 cell division protein DedD compare
BWI76_RS19865 +1.5 3.0 ecotin compare
BWI76_RS25065 +1.4 2.8 polyribonucleotide nucleotidyltransferase compare
BWI76_RS13250 +1.4 1.7 cytochrome b561 compare
BWI76_RS12170 +1.3 1.3 hypothetical protein compare
BWI76_RS18550 +1.2 2.1 tRNA-Asn compare
BWI76_RS14065 +1.2 2.3 hypothetical protein compare
BWI76_RS23020 +1.2 2.7 cobalamin biosynthesis protein CbiQ compare
BWI76_RS21245 +1.2 2.4 nitrogen regulatory protein P-II compare
BWI76_RS19470 +1.1 2.6 DNA-binding response regulator compare
BWI76_RS23690 +1.1 1.7 putative glyoxalase/bleomycin resistance protein/dioxygenase compare
BWI76_RS03045 +1.1 1.4 hypothetical protein compare
BWI76_RS17980 +1.1 3.9 RNA chaperone ProQ compare
BWI76_RS23125 +1.0 2.1 propanediol dehydratase small subunit compare
BWI76_RS14575 +1.0 2.7 TENA/THI-4 family protein compare
BWI76_RS18755 +1.0 1.4 adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase compare
BWI76_RS21780 +0.9 3.8 S-(hydroxymethyl)glutathione synthase compare
BWI76_RS03595 +0.9 1.6 ethanolamine utilization protein EutM compare
BWI76_RS14320 +0.9 2.3 hypothetical protein compare
BWI76_RS07740 +0.9 1.7 Fe2+-enterobactin ABC transporter substrate-binding protein compare
BWI76_RS16590 +0.9 2.9 short-chain dehydrogenase compare
BWI76_RS01350 +0.9 1.0 NAD(P)H-flavin reductase compare
BWI76_RS00720 +0.9 1.5 DNA-binding response regulator compare
BWI76_RS06665 +0.9 2.1 membrane protein compare
BWI76_RS26575 +0.9 3.0 universal stress protein B compare
BWI76_RS16935 +0.9 1.1 shikimate dehydrogenase compare
BWI76_RS07755 +0.9 2.7 isochorismatase compare
BWI76_RS03285 +0.9 3.1 hypothetical protein compare
BWI76_RS18605 +0.9 1.7 oxidoreductase molybdopterin-binding protein compare
BWI76_RS02825 +0.9 1.8 putative acyltransferase domain protein compare
BWI76_RS21565 +0.9 1.1 outer membrane protein assembly factor BamE compare
BWI76_RS21675 +0.8 1.4 hypothetical protein compare
BWI76_RS12070 +0.8 1.0 hypothetical protein compare
BWI76_RS01195 +0.8 1.2 membrane protein compare
BWI76_RS15795 +0.8 2.2 bacteriophage CII family protein compare
BWI76_RS05235 +0.8 1.2 hypothetical protein compare
BWI76_RS12860 +0.8 1.0 hypothetical protein compare
BWI76_RS14770 +0.8 1.1 PTS IIA 2 domain protein compare
BWI76_RS13480 +0.8 1.7 XRE family transcriptional regulator compare
BWI76_RS16160 +0.8 2.0 LysR family transcriptional regulator compare
BWI76_RS17470 +0.8 2.1 MerR family transcriptional regulator compare
BWI76_RS10950 +0.8 2.2 MFS transporter compare
BWI76_RS22640 +0.8 1.3 hypothetical protein compare
BWI76_RS09155 +0.8 2.5 undecaprenyl-diphosphatase compare
BWI76_RS16120 +0.8 1.9 4-carboxymuconolactone decarboxylase compare
BWI76_RS23015 +0.8 1.3 cobalt transporter ATP-binding subunit compare
BWI76_RS20885 +0.8 3.1 tRNA(Met) cytidine acetyltransferase TmcA compare
BWI76_RS24110 +0.8 1.7 YggU family protein compare
BWI76_RS01940 +0.8 1.9 hypothetical protein compare
BWI76_RS04175 +0.8 2.6 energy-dependent translational throttle protein EttA compare
BWI76_RS14170 +0.8 1.8 hypothetical protein compare
BWI76_RS15990 +0.8 3.9 serine protease compare
BWI76_RS01585 +0.8 2.9 transcriptional regulator compare
BWI76_RS03105 +0.8 1.0 myo-inosose-2 dehydratase compare
BWI76_RS13970 +0.8 1.3 ABC transporter compare
BWI76_RS16485 +0.8 1.1 ribonuclease T compare
BWI76_RS06745 +0.8 1.2 N-acetyltransferase GCN5 compare
BWI76_RS13105 +0.8 2.7 phenylacetate-CoA oxygenase subunit PaaJ compare
BWI76_RS08380 +0.8 1.1 endonuclease VIII compare
BWI76_RS22955 +0.8 2.4 transcriptional regulator GcvA compare
BWI76_RS20790 +0.8 4.9 aldehyde dehydrogenase compare
BWI76_RS02225 +0.7 2.2 phosphonate C-P lyase system protein PhnG compare
BWI76_RS10750 +0.7 3.4 pyrimidine utilization transport protein G compare
BWI76_RS11250 +0.7 1.2 spermidine/putrescine ABC transporter permease PotB compare
BWI76_RS17770 +0.7 1.1 isomerase/hydrolase compare
BWI76_RS16355 +0.7 1.4 electron transport complex subunit A compare
BWI76_RS13360 +0.7 3.0 benzoate transporter compare
BWI76_RS00290 +0.7 2.6 Ribokinase (EC 2.7.1.15) (from data) compare
BWI76_RS07885 +0.7 1.8 sugar ABC transporter permease compare
BWI76_RS19240 +0.7 1.4 ABC transporter substrate-binding protein compare
BWI76_RS07820 +0.7 1.1 S-methyl-5-thioribose kinase compare
BWI76_RS12985 +0.7 1.3 transcriptional regulator compare
BWI76_RS15950 +0.7 1.1 dethiobiotin synthase compare
BWI76_RS09690 +0.7 1.6 dimethyl sulfoxide reductase compare
BWI76_RS10955 +0.7 1.0 hypothetical protein compare
BWI76_RS10055 +0.7 2.4 AraC family transcriptional regulator compare
BWI76_RS14390 +0.7 0.7 hypothetical protein compare
BWI76_RS15135 +0.7 1.8 hypothetical protein compare
BWI76_RS12080 +0.7 2.6 hypothetical protein compare
BWI76_RS06440 +0.7 2.3 AP endonuclease compare
BWI76_RS04060 +0.7 1.3 hypothetical protein compare
BWI76_RS17500 +0.7 2.7 knotted carbamoyltransferase YgeW compare
BWI76_RS10380 +0.7 4.0 polar amino acid ABC transporter inner membrane subunit compare
BWI76_RS05790 +0.7 1.3 phage DNA-binding protein compare
BWI76_RS00715 +0.7 2.0 two-component sensor histidine kinase compare
BWI76_RS09860 +0.7 1.4 hypothetical protein compare
BWI76_RS16655 +0.7 2.2 CatA-like O-acetyltransferase compare
BWI76_RS10540 +0.7 3.1 allantoinase compare
BWI76_RS18295 +0.7 2.6 tyrosine transporter TyrP compare
BWI76_RS19375 +0.7 1.3 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase compare
BWI76_RS15150 +0.7 1.7 outer membrane efflux protein compare
BWI76_RS24250 +0.7 3.2 hypothetical protein compare
BWI76_RS13095 +0.7 1.2 phenylacetate-CoA oxygenase subunit PaaB compare
BWI76_RS16075 +0.7 1.0 oxidoreductase compare
BWI76_RS00295 +0.7 3.1 transcriptional regulator RbsR compare
BWI76_RS15775 +0.7 1.5 replication protein compare
BWI76_RS09820 +0.7 2.7 hypothetical protein compare
BWI76_RS06680 +0.7 0.9 hypothetical protein compare
BWI76_RS16900 +0.7 1.0 4-hydroxy-2-oxovalerate aldolase compare
BWI76_RS27670 +0.7 2.2 LysR family transcriptional regulator compare
BWI76_RS08650 +0.7 1.2 molybdate ABC transporter permease compare
BWI76_RS08600 +0.7 2.4 3-deoxy-7-phosphoheptulonate synthase compare
BWI76_RS13880 +0.7 2.7 lysine transporter LysE compare
BWI76_RS13395 +0.7 3.9 cytochrome D ubiquinol oxidase subunit I compare
BWI76_RS07760 +0.7 1.9 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase compare
BWI76_RS10870 +0.7 1.7 nicotinamidase compare
BWI76_RS27865 +0.7 2.2 hypothetical protein compare
BWI76_RS26285 +0.7 1.6 glycerophosphodiester phosphodiesterase compare
BWI76_RS24270 +0.7 1.2 membrane protein compare
BWI76_RS23000 +0.7 2.0 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase compare
BWI76_RS18410 +0.7 1.5 drug/metabolite exporter YedA compare
BWI76_RS08765 +0.7 1.7 8-amino-7-oxononanoate synthase compare
BWI76_RS11520 +0.7 0.7 hypothetical protein compare
BWI76_RS22815 +0.7 4.2 hybrid sensor histidine kinase/response regulator compare
BWI76_RS24245 +0.6 3.3 bifunctional glutathionylspermidine amidase/glutathionylspermidine synthase compare
BWI76_RS08640 +0.6 1.3 multidrug efflux pump-associated protein, AcrZ family compare
BWI76_RS14155 +0.6 1.7 transketolase compare
BWI76_RS07595 +0.6 1.6 putative oxidoreductase compare
BWI76_RS24925 +0.6 1.5 DnaA initiator-associating protein DiaA compare
BWI76_RS00240 +0.6 1.7 FMN-binding protein MioC compare
BWI76_RS13050 +0.6 1.3 transcriptional regulator compare
BWI76_RS17765 +0.6 1.4 hypothetical protein compare
BWI76_RS10295 +0.6 1.2 short chain dehydrogenase/reductase family oxidoreductase compare
BWI76_RS09025 +0.6 1.4 GntR family transcriptional regulator compare
BWI76_RS21130 +0.6 1.2 Fe-S assembly protein IscX compare
BWI76_RS13240 +0.6 1.0 hypothetical protein compare
BWI76_RS11125 +0.6 0.9 metal-dependent hydrolase compare
BWI76_RS16895 +0.6 0.8 3-(3-hydroxy-phenyl)propionate transporter MhpT compare
BWI76_RS06815 +0.6 0.9 adenine phosphoribosyltransferase compare
BWI76_RS13195 +0.6 1.6 glutamate dehydrogenase compare
BWI76_RS10760 +0.6 1.5 nitroreductase family protein compare
BWI76_RS21460 +0.6 1.0 translation inhibitor protein RaiA compare
BWI76_RS06325 +0.6 1.0 hypothetical protein compare
BWI76_RS20695 +0.6 1.1 sulfate/thiosulfate transporter permease subunit compare
BWI76_RS11485 +0.6 2.2 serine protein kinase PrkA compare
BWI76_RS09145 +0.6 2.0 serine-type D-Ala-D-Ala carboxypeptidase compare
BWI76_RS21070 +0.6 1.2 outer membrane protein assembly factor BamB compare
BWI76_RS04955 +0.6 0.7 hypoxanthine phosphoribosyltransferase compare
BWI76_RS17045 +0.6 0.7 hypothetical protein compare
BWI76_RS04150 +0.6 2.1 lipoate--protein ligase A compare
BWI76_RS00025 +0.6 0.7 hypothetical protein compare
BWI76_RS09335 +0.6 0.7 baseplate assembly protein W compare
BWI76_RS13805 +0.6 1.7 inorganic diphosphatase compare
BWI76_RS06075 +0.6 1.6 taurine transporter subunit compare
BWI76_RS00940 +0.6 2.9 transcriptional regulator HdfR compare
BWI76_RS06880 +0.6 2.1 biopolymer transport protein ExbD/TolR compare
BWI76_RS11525 +0.6 1.3 HNH endonuclease compare
BWI76_RS15470 +0.6 3.0 dipeptidyl carboxypeptidase II compare
BWI76_RS04715 +0.6 0.6 division/cell wall cluster transcriptional repressor MraZ compare
BWI76_RS24795 +0.6 1.9 hypothetical protein compare
BWI76_RS25375 +0.6 1.7 hypothetical protein compare
BWI76_RS06545 +0.6 1.4 peptidylprolyl isomerase compare
BWI76_RS14610 +0.6 1.1 putative hydrolase compare
BWI76_RS23025 +0.6 1.3 cobalt ABC transporter substrate-binding protein CbiN compare
BWI76_RS13930 +0.6 1.3 putative LysR-family transcriptional regulator compare
BWI76_RS11515 +0.6 0.7 peptide-methionine (R)-S-oxide reductase compare
BWI76_RS11380 +0.6 1.6 iron-dicitrate transporter substrate-binding subunit compare
BWI76_RS24500 +0.6 1.1 urease subunit gamma compare
BWI76_RS06015 +0.6 1.0 hypothetical protein compare
BWI76_RS05985 +0.6 1.3 branched-chain amino acid ABC transporter permease compare
BWI76_RS11970 +0.6 1.9 stress response translation initiation inhibitor YciH compare
BWI76_RS23530 +0.6 0.8 MarR family transcriptional regulator compare
BWI76_RS02485 +0.6 2.7 polar amino acid ABC transporter (PAAT) family, periplasmic amino acid-binding protein compare
BWI76_RS20925 +0.6 1.9 peptidase M48 compare
BWI76_RS20720 +0.6 0.8 hypothetical protein compare
BWI76_RS16965 +0.6 1.5 murein lipoprotein compare
BWI76_RS19835 +0.6 1.7 nucleoid-associated protein YejK compare
BWI76_RS09625 +0.6 1.0 hypothetical protein compare
BWI76_RS04560 +0.6 1.2 holo-ACP synthase CitX compare
BWI76_RS21340 +0.6 1.4 SoxR reducing system protein RseC compare
BWI76_RS05965 +0.6 1.2 hypothetical protein compare
BWI76_RS23880 +0.6 1.8 Aminomethyltransferase (EC 2.1.2.10) (from data) compare
BWI76_RS18235 +0.6 1.3 trehalose-phosphatase compare
BWI76_RS09470 +0.6 1.7 putrescine ABC transporter permease compare
BWI76_RS19455 +0.6 3.7 hypothetical protein compare
BWI76_RS06340 +0.6 0.8 hypothetical protein compare
BWI76_RS11300 +0.6 0.8 cupin compare
BWI76_RS12040 +0.5 0.6 hypothetical protein compare
BWI76_RS12105 +0.5 2.3 hypothetical protein compare
BWI76_RS11665 +0.5 1.5 exodeoxyribonuclease III compare
BWI76_RS27660 +0.5 2.3 hypothetical protein compare
BWI76_RS18600 +0.5 2.6 HupC/HyaC/HydC family protein compare
BWI76_RS16135 +0.5 3.0 acetyl-CoA acetyltransferase compare
BWI76_RS16025 +0.5 1.2 triphosphoribosyl-dephospho-CoA synthase compare
BWI76_RS11035 +0.5 1.7 putative LysR-family transcriptional regulator compare
BWI76_RS12420 +0.5 0.7 peptide ABC transporter substrate-binding protein SapA compare
BWI76_RS11985 +0.5 3.0 hypothetical protein compare
BWI76_RS13560 +0.5 0.6 amino acid ABC transporter substrate-binding subunit compare
BWI76_RS10905 +0.5 2.0 hypothetical protein compare
BWI76_RS06775 +0.5 2.8 multidrug efflux RND transporter permease subunit compare
BWI76_RS19860 +0.5 2.0 hypothetical protein compare
BWI76_RS02920 +0.5 1.3 addiction module toxin RelE compare
BWI76_RS08330 +0.5 0.8 hypothetical protein compare
BWI76_RS14245 +0.5 1.0 carboxymuconolactone decarboxylase family protein compare


Specific Phenotypes

For 3 genes in this experiment

For carbon source Inosine in Klebsiella michiganensis M5al

For carbon source Inosine across organisms