Experiment set5IT064 for Sinorhizobium meliloti 1021

Compare to:

Defined media with L-Histidine

200 most important genes:

  gene name fitness t score description  
SMc01494 -7.2 -7.0 phosphoserine phosphatase compare
SMc00236 -7.2 -5.0 Indole-3-glycerol phosphate synthase compare
SMc02767 -7.1 -4.9 N-(5'-phosphoribosyl)anthranilate isomerase compare
SMc00495 -6.8 -4.7 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
SMc03797 -6.8 -8.1 homoserine O-succinyltransferase compare
SMc02899 -6.8 -8.1 prephenate dehydratase compare
SMc04405 -6.8 -6.6 3-isopropylmalate dehydrogenase compare
SMc04045 -6.8 -4.7 dihydroxy-acid dehydratase compare
SMc01726 -6.7 -8.0 acetylglutamate kinase compare
SMc00235 -6.7 -6.5 anthranilate phosphoribosyltransferase compare
SMc00640 -6.4 -6.3 phosphoserine aminotransferase compare
SMc04002 -6.4 -6.2 phosphoribosylaminoimidazole carboxylase ATPase subunit compare
SMc02766 -6.3 -14.2 tryptophan synthase subunit beta compare
SMc02717 -6.3 -6.1 2-isopropylmalate synthase compare
SMc01801 -6.3 -4.3 N-acetylglutamylphosphate reductase (EC 1.2.1.38) (from data) compare
SMc01361 -6.2 -4.2 dihydroorotase compare
SMa1635 -6.1 -2.4 hypothetical protein compare
SMc02725 -6.0 -12.1 anthranilate synthase compare
SMc01431 -5.9 -10.6 acetolactate synthase 3 catalytic subunit compare
SMc00711 -5.8 -4.0 cyclohexadienyl dehydrogenase compare
SMc00488 -5.8 -18.2 phosphoribosylformylglycinamidine synthase II compare
SMc03823 -5.8 -11.7 isopropylmalate isomerase large subunit compare
SMc01843 -5.7 -12.6 5,10-methylenetetrahydrofolate reductase compare
SMc00494 -5.7 -2.3 phosphoribosylformylglycinamidine synthase subunit PurS compare
SMc00993 -5.6 -6.7 phosphoribosylamine--glycine ligase compare
SMc02137 -5.6 -5.4 ornithine carbamoyltransferase compare
SMc04028 -5.6 -17.6 glutamate synthase compare
SMc03070 -5.6 -6.6 glucose-6-phosphate 1-dehydrogenase compare
SMc02245 -5.6 -7.6 dihydroorotate dehydrogenase 2 compare
SMc00412 -5.6 -3.8 orotidine 5'-phosphate decarboxylase compare
SMc03112 -5.6 -15.6 B12-dependent methionine synthase compare
SMc01054 -5.5 -5.3 required for sulfate utilization, putative electron source for sulfite reductase CysI (from data) compare
SMc00815 -5.4 -3.6 inosine 5'-monophosphate dehydrogenase compare
SM_b21177 -5.4 -6.4 phosphate uptake ABC transporter ATP-binding protein compare
SMc00131 -5.4 -16.4 transcriptional regulator compare
SMc03776 -5.3 -3.6 gamma-glutamyl kinase compare
SMc01430 -5.2 -6.5 acetolactate synthase 3 regulatory subunit compare
SMc02217 -5.2 -7.9 O-succinylhomoserine sulfhydrylase compare
SMc00615 -5.1 -9.2 phosphoribosylaminoimidazole synthetase compare
SMc01360 -5.1 -3.5 aspartate carbamoyltransferase catalytic subunit compare
SMc02123 -5.1 -4.5 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
SMc00554 -5.1 -8.4 amidophosphoribosyltransferase compare
SMc00493 -5.1 -6.0 phosphoribosylformylglycinamidine synthase I compare
SMc00091 -5.0 -12.1 sulfate adenylyltransferase compare
SMc02165 -5.0 -8.9 orotate phosphoribosyltransferase compare
SMc02166 -5.0 -12.2 dihydroorotase compare
SMc04026 -5.0 -9.3 glutamate synthase compare
SMc00092 -4.9 -11.7 phosphoadenosine phosphosulfate reductase compare
SMc00614 -4.8 -8.6 phosphoribosylglycinamide formyltransferase compare
SMc00641 -4.8 -5.7 D-3-phosphoglycerate dehydrogenase compare
SMc00293 -4.8 -9.1 homoserine dehydrogenase compare
SMc00090 -4.7 -10.0 sulfate adenylyltransferase compare
SMc02765 -4.7 -12.3 tryptophan synthase subunit alpha compare
SMc02124 -4.7 -14.5 nitrite reductase compare
SMc03826 -4.7 -3.2 argininosuccinate synthase compare
SMc03229 -4.6 -3.1 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase compare
SMc03777 -4.6 -8.7 gamma-glutamyl phosphate reductase compare
SMc03981 -4.4 -6.0 phosphoglycerate kinase compare
SMc02755 -4.4 -7.3 S-adenosyl-L-homocysteine hydrolase compare
SM_b21174 -4.4 -4.2 phosphate uptake ABC transporter permease compare
SMc02138 -4.3 -9.1 acetylornithine transaminase compare
SM_b21175 -4.2 -3.4 phosphate uptake ABC transporter permease compare
SMc04088 -4.1 -7.6 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase compare
SMc04001 -4.1 -1.6 phosphoribosylaminoimidazole carboxylase catalytic subunit protein compare
SMc02707 -4.1 -5.9 hypothetical protein compare
SM_b21176 -4.0 -6.0 phosphate uptake ABC transporter substrate-binding protein precursor compare
SMc03068 -4.0 -9.9 phosphogluconate dehydratase compare
SMc03763 -3.8 -2.6 cytosine-specific methyltransferase compare
SMc01053 -3.7 -5.7 siroheme synthase compare
SMc02115 -3.7 -2.0 hypothetical protein compare
SMc01881 -3.7 -4.1 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
SMc00876 -3.6 -8.0 ATP-binding MRP protein compare
SMc03979 -3.6 -2.4 glyceraldehyde-3-phosphate dehydrogenase compare
SMc01569 -3.5 -1.9 carbamoyl phosphate synthase small subunit compare
SMc01206 -3.5 -3.2 queuine tRNA-ribosyltransferase compare
SMc04346 -3.5 -4.6 ketol-acid reductoisomerase compare
SMc01147 -3.4 -4.6 coproporphyrinogen III oxidase compare
SMc00294 -3.4 -10.5 aminotransferase compare
SMc01441 -3.3 -7.3 membrane bound protease compare
SMc03795 -3.3 -1.8 isopropylmalate isomerase small subunit compare
SMc03978 -3.3 -3.2 transketolase compare
SMc01770 -3.2 -1.5 serine hydroxymethyltransferase compare
SMc02058 -3.1 -3.3 YAJC protein compare
SMc01880 -3.1 -2.1 pantoate--beta-alanine ligase compare
SMc01215 -3.1 -2.1 carbamoyl phosphate synthase large subunit compare
SMc02246 -3.1 -1.2 hypothetical protein compare
SMc02102 -3.1 -5.7 hypothetical protein compare
SMc03924 -3.0 -11.9 glycogen synthase compare
SMc03100 -3.0 -2.3 hypothetical protein compare
SMc00914 -2.9 -6.3 oxidoreductase compare
SMc01440 -2.9 -5.2 hydrolase serine protease transmembrane protein compare
SMc00414 -2.8 -12.7 hypothetical protein compare
SMc02147 -2.8 -7.8 phosphate regulon sensor histidine kinase transmembrane protein compare
SMc02425 -2.8 -5.0 transcriptional regulator compare
SMc01578 -2.7 -14.2 aspartate aminotransferase compare
SMc01845 -2.6 -3.0 transglycosylase transmembrane protein compare
SMc01208 -2.6 -3.6 peptidyl-prolyl cis-trans isomerase B protein compare
SMc01438 -2.6 -6.0 protease precursor signal peptide protein compare
SMc00419 -2.5 -5.4 glutathione synthetase compare
SMc00673 -2.4 -12.8 Formiminoglutamic iminohydrolase (EC 3.5.3.13) (from data) compare
SMa0789 -2.4 -4.4 GntR family transcriptional regulator compare
SMc00712 -2.3 -2.7 hypothetical protein compare
SMc00017 -2.3 -1.5 homoserine kinase compare
SMc01842 -2.3 -3.3 methyltransferase transcription regulator protein compare
SMc00838 -2.3 -5.5 hypothetical protein compare
SMc04296 -2.3 -1.7 cell division protein FtsZ compare
SMc00361 -2.3 -2.6 hypothetical protein compare
SMc03849 -2.2 -2.5 heme exporter C (cytochrome C-type biogenesis protein) transmembrane compare
SMc02835 -2.2 -6.4 glucokinase compare
SMc00492 -2.2 -1.4 hypothetical protein compare
SMc02683 -2.1 -3.1 hypothetical protein compare
SMc00295 -2.1 -2.1 hypothetical protein compare
SMc02983 -2.1 -7.5 ornithine, DAP, or arginine decarboxylase compare
SMc00619 -2.1 -2.8 hypothetical protein compare
SMc02753 -2.1 -2.3 PTS system transporter subunit IIA compare
SMc00334 -2.0 -2.0 cytidylate kinase compare
SMc03046 -2.0 -6.6 transcriptional regulator compare
SMc01124 -2.0 -6.3 PII uridylyl-transferase compare
SMc01850 -2.0 -3.5 hypothetical protein compare
SMc01183 -2.0 -2.3 LexA repressor compare
SMc00450 -2.0 -4.6 protoheme IX farnesyltransferase compare
SM_b20048 -2.0 -9.2 transcriptional regulator compare
SMc03967 -1.9 -1.4 Holliday junction resolvase compare
SMc02434 -1.9 -3.2 hypothetical protein compare
SM_b20948 -1.8 -2.2 glucosyltransferase compare
SMc03069 -1.8 -2.8 6-phosphogluconolactonase compare
SMc02362 -1.8 -4.7 cytochrome c-type biogenesis protein CcmE compare
SMc02685 -1.8 -4.7 hypothetical protein compare
SMc01028 -1.8 -10.6 phosphopyruvate hydratase compare
SMc02641 -1.7 -5.2 UDP-glucose 6-dehydrogenase compare
SMc01368 -1.7 -5.4 transport transmembrane protein compare
SMc00302 -1.6 -3.8 hypothetical protein compare
SM_b20902 -1.6 -9.7 sugar uptake ABC transporter substrate-binding protein precursor compare
SMc02833 -1.6 -2.3 penicillin-insensitive murein endopeptidase compare
SMc02850 -1.6 -4.6 DNA polymerase I compare
SMc02582 -1.6 -3.7 hypothetical protein compare
SM_b20904 -1.6 -3.2 sugar uptake ABC transporter ATP-binding protein compare
SMc02856 -1.6 -9.1 penicillin-binding protein compare
SMc03974 -1.5 -4.9 hypothetical protein compare
SMc04330 -1.5 -3.3 trimethylamine methyltransferase compare
SMc02142 -1.5 -4.6 phosphate transporter ATP-binding protein compare
SMc02724 -1.5 -2.8 hypothetical protein compare
SMa2215 -1.5 -4.5 GntR family transcriptional regulator compare
SMc03242 -1.5 -3.4 GTP-binding protein compare
SMc02140 -1.5 -1.8 phosphate regulon transcriptional regulatory protein compare
SMc02510 -1.5 -0.9 ferric uptake regulation protein compare
SM_b21164 -1.5 -7.0 N-formylglutamate deformylase (EC 3.5.1.68) (from data) compare
SMc00012 -1.5 -1.8 cytochrome C oxidase assembly protein compare
SMc02778 -1.4 -1.3 hydroxyacid aldolase compare
SMc03899 -1.4 -1.5 hypothetical protein compare
SMc01097 -1.4 -2.7 hypothetical protein compare
SMc02144 -1.4 -5.5 phosphate ABC transporter permease compare
SMc00709 -1.4 -2.6 hypothetical protein compare
SMc00405 -1.4 -6.1 hypothetical protein compare
SMa1174 -1.4 -1.9 hypothetical protein compare
SM_b20903 -1.4 -5.8 sugar uptake ABC transporter permease compare
SMc02838 -1.3 -3.9 phosphoglyceromutase compare
SMc02867 -1.3 -3.2 multidrug-efflux system transmembrane protein compare
SMc02247 -1.3 -1.4 signal peptide protein compare
SMc03993 -1.3 -4.8 hypothetical protein compare
SMc00982 -1.3 -5.2 dioxygenase compare
SMc04213 -1.3 -2.3 diacylglycerol kinase compare
SMc04348 -1.2 -1.3 transcriptional regulator compare
SM_b21163 -1.2 -5.9 Urocanate hydratase (EC 4.2.1.49) (from data) compare
SMa0734 -1.2 -1.8 hypothetical protein compare
SMc01187 -1.2 -1.2 rare lipoprotein A compare
SMc02306 -1.2 -1.4 hypothetical protein compare
SMc02450 -1.2 -3.2 bifunctional ornithine acetyltransferase/N-acetylglutamate synthase compare
SMc03850 -1.2 -1.5 heme exporter D (cytochrome C-type biogenesis protein) transmembrane compare
SMa1365 -1.2 -1.1 ATP-binding protein compare
SMc02121 -1.2 -1.3 ABC transporter for L-Glutamine, L-Histidine, and other L-amino acids, ATPase component (from data) compare
SMc01579 -1.1 -1.3 hypothetical protein compare
SMc02363 -1.1 -3.0 cytochrome C-type biogenesis transmembrane protein compare
SMa1323 -1.1 -2.2 Transcription regulator compare
SMc03050 -1.1 -3.1 flagellar biosynthesis regulatory protein FlaF compare
SMc02812 -1.1 -2.4 hypothetical protein compare
SMc01280 -1.1 -2.0 protease compare
SMc02897 -1.1 -3.3 cytochrome C transmembrane protein compare
SM_b20392 -1.1 -3.4 transcriptional regulator NanR compare
SM_b21166 -1.1 -4.3 Imidazolonepropionase (EC 3.5.2.7) (from data) compare
SM_b20773 -1.1 -3.6 GntR family transcriptional regulator compare
SMc02077 -1.1 -3.1 exodeoxyribonuclease III protein compare
SMc00010 -1.1 -2.0 cytochrome C oxidase polypeptide I transmembrane protein compare
SMc02985 -1.0 -3.9 hypothetical protein compare
SMc00296 -1.0 -5.7 POLY3-hydroxybutyrate polymerase compare
SMc01568 -1.0 -1.8 hypothetical protein compare
SMc02521 -1.0 -2.4 glycerol-3-phosphate regulon repressor transcription regulator protein compare
SMc04005 -1.0 -5.5 pyruvate kinase compare
SMc03941 -1.0 -1.6 hypothetical protein compare
SMc03935 -1.0 -7.0 hypothetical protein compare
SMc02543 -1.0 -3.2 hypothetical protein compare
SM_b20746 -1.0 -0.8 hypothetical protein compare
SMc02234 -1.0 -2.0 hypothetical protein compare
SMc00088 -1.0 -1.6 hypothetical protein compare
SMc04456 -1.0 -4.2 chaperone protein compare
SMa0112 -0.9 -1.7 hypothetical protein compare
SMc02904 -0.9 -1.5 hypothetical protein compare
SM_b20307 -0.9 -0.7 dihydroxyacetone kinase compare
SMc00691 -0.9 -2.5 site-specific tyrosine recombinase XerD compare
SMc00928 -0.9 -1.0 signal peptide protein compare


Specific Phenotypes

For 4 genes in this experiment

For nutrient L-Histidine in Sinorhizobium meliloti 1021

For nutrient L-Histidine across organisms