Experiment set5IT064 for Shewanella loihica PV-4

Compare to:

LB with Dimethyl Sulfoxide 5 vol%

200 most detrimental genes:

  gene name fitness t score description  
Shew_2049 +2.5 16.7 DNA-binding transcriptional regulator HexR (RefSeq) compare
Shew_3311 +2.5 17.1 RNA polymerase factor sigma-54 (RefSeq) compare
Shew_3561 +2.4 15.8 nitrogen metabolism transcriptional regulator, NtrC, Fis family (RefSeq) compare
Shew_1298 guaA +2.3 21.1 bifunctional GMP synthase/glutamine amidotransferase protein (RefSeq) compare
Shew_3560 +2.3 16.8 signal transduction histidine kinase, nitrogen specific, NtrB (RefSeq) compare
Shew_2572 +2.3 12.1 enoyl-CoA hydratase/isomerase (RefSeq) compare
Shew_2637 +2.2 12.1 PII uridylyl-transferase (RefSeq) compare
Shew_1301 +2.1 17.9 phosphoribosylformylglycinamidine synthase (RefSeq) compare
Shew_0330 +2.0 2.1 nifR3 family TIM-barrel protein (RefSeq) compare
Shew_0763 +1.9 7.8 putative PAS/PAC sensor protein (RefSeq) compare
Shew_0867 +1.9 4.1 malate dehydrogenase (RefSeq) compare
Shew_1819 +1.8 7.9 GntR family transcriptional regulator (RefSeq) compare
Shew_1224 +1.7 12.5 sodium:dicarboxylate symporter (RefSeq) compare
Shew_2502 +1.7 9.2 ABC transporter-related protein (RefSeq) compare
Shew_1512 +1.7 10.1 phosphoribosylglycinamide formyltransferase (RefSeq) compare
Shew_2000 +1.6 3.5 glyceraldehyde-3-phosphate dehydrogenase (RefSeq) compare
Shew_2837 +1.6 2.3 transcription elongation factor GreA (RefSeq) compare
Shew_2302 +1.6 11.4 amidophosphoribosyltransferase (RefSeq) compare
Shew_1013 +1.6 15.1 aspartate carbamoyltransferase (RefSeq) compare
Shew_0585 +1.6 5.6 cAMP-regulatory protein (RefSeq) compare
Shew_3554 glnA +1.5 4.2 glutamine synthetase (RefSeq) compare
Shew_1425 +1.5 8.2 adenylyl-sulfate kinase (RefSeq) compare
Shew_3413 +1.5 13.1 phosphoribosylamine--glycine ligase (RefSeq) compare
Shew_1128 +1.5 9.7 LysR family transcriptional regulator (RefSeq) compare
Shew_0618 +1.4 3.8 hypothetical protein (RefSeq) compare
Shew_2349 +1.4 3.9 integral membrane sensor signal transduction histidine kinase (RefSeq) compare
Shew_2320 +1.4 10.0 RNA methyltransferase (RefSeq) compare
Shew_2498 +1.3 2.7 extracellular solute-binding protein (RefSeq) compare
Shew_1341 +1.3 4.6 anti-sigma-28 factor, FlgM (RefSeq) compare
Shew_3709 +1.3 9.7 2-amino-3-ketobutyrate coenzyme A ligase (RefSeq) compare
Shew_3710 tdh +1.3 8.1 L-threonine 3-dehydrogenase (RefSeq) compare
Shew_1092 +1.2 10.5 amino acid carrier protein (RefSeq) compare
Shew_0296 +1.2 2.2 heat shock protein Hsp20 (RefSeq) compare
Shew_0755 +1.2 5.8 fructose-1,6-bisphosphate aldolase (RefSeq) compare
Shew_2382 +1.2 10.7 cysteine synthase A (RefSeq) compare
Shew_1058 +1.2 6.9 holo-acyl-carrier-protein synthase (RefSeq) compare
Shew_1287 +1.2 4.5 hypothetical protein (RefSeq) compare
Shew_3412 purH +1.2 7.7 bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (RefSeq) compare
Shew_2839 +1.1 9.3 carbamoyl phosphate synthase small subunit (RefSeq) compare
Shew_0534 +1.1 4.6 major facilitator transporter (RefSeq) compare
Shew_1922 +1.1 5.2 phosphoglucomutase (RefSeq) compare
Shew_3295 +1.1 6.5 AFG1 family ATPase (RefSeq) compare
Shew_0565 +1.1 2.4 tRNA delta(2)-isopentenylpyrophosphate transferase (RefSeq) compare
Shew_2481 +1.1 7.4 porin (RefSeq) compare
Shew_3487 pyrE +1.1 5.2 orotate phosphoribosyltransferase (RefSeq) compare
Shew_1673 fabG +1.1 3.0 3-ketoacyl-(acyl-carrier-protein) reductase (RefSeq) compare
Shew_2584 +1.1 6.9 electron transfer flavoprotein beta-subunit (RefSeq) compare
Shew_0421 +1.1 1.9 phage shock protein C, PspC (RefSeq) compare
Shew_0086 +1.1 9.4 electron-transferring-flavoproteindehydrogenase (RefSeq) compare
Shew_2785 +1.0 1.4 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein (RefSeq) compare
Shew_2838 carB +1.0 6.6 carbamoyl phosphate synthase large subunit (RefSeq) compare
Shew_2573 +1.0 7.5 carbamoyl-phosphate synthase L chain, ATP-binding (RefSeq) compare
Shew_2008 +1.0 1.1 short-chain dehydrogenase/reductase SDR (RefSeq) compare
Shew_3621 +1.0 1.2 RNA-binding S4 domain-containing protein (RefSeq) compare
Shew_2571 +1.0 5.9 propionyl-CoA carboxylase (RefSeq) compare
Shew_1210 +0.9 4.2 stationary-phase survival protein SurE (RefSeq) compare
Shew_1439 +0.9 7.2 maleylacetoacetate isomerase (RefSeq) compare
Shew_1402 +0.9 7.0 glucose-1-phosphate thymidylyltransferase (RefSeq) compare
Shew_2416 +0.9 1.4 chorismate synthase (RefSeq) compare
Shew_2141 +0.9 4.4 lytic murein transglycosylase (RefSeq) compare
Shew_2228 +0.9 7.9 inosine kinase (RefSeq) compare
Shew_1036 +0.9 4.4 putative adenylate/guanylate cyclase (RefSeq) compare
Shew_3718 +0.8 1.6 hypothetical protein (RefSeq) compare
Shew_3499 +0.8 3.0 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (RefSeq) compare
Shew_2389 +0.8 5.3 hypothetical protein (RefSeq) compare
Shew_3727 +0.8 4.4 shikimate 5-dehydrogenase (RefSeq) compare
Shew_1052 +0.8 4.5 GTP-binding protein LepA (RefSeq) compare
Shew_1714 +0.8 3.4 alpha/beta hydrolase fold (RefSeq) compare
Shew_1593 +0.8 2.4 ribonuclease (RefSeq) compare
Shew_1185 glyA +0.8 4.2 serine hydroxymethyltransferase (RefSeq) compare
Shew_2812 deoD +0.8 4.5 purine nucleoside phosphorylase (RefSeq) compare
Shew_1230 +0.8 2.1 phosphoribosylaminoimidazole carboxylase, catalytic subunit (RefSeq) compare
Shew_1213 +0.8 1.7 RpoD family RNA polymerase sigma factor (RefSeq) compare
Shew_1007 +0.7 0.6 major outer membrane lipoprotein, putative (RefSeq) compare
Shew_0580 +0.7 2.7 succinylglutamic semialdehyde dehydrogenase (RefSeq) compare
Shew_3598 +0.7 1.2 AsnC family transcriptional regulator (RefSeq) compare
Shew_0022 +0.7 4.0 TrkH family potassium uptake protein (RefSeq) compare
Shew_3224 +0.7 5.9 hypothetical protein (RefSeq) compare
Shew_0459 +0.7 3.2 PAS/PAC sensor hybrid histidine kinase (RefSeq) compare
Shew_2664 +0.7 5.0 transcriptional regulator, putative (RefSeq) compare
Shew_3394 +0.7 1.3 MscS mechanosensitive ion channel (RefSeq) compare
Shew_1189 +0.7 6.0 3,4-dihydroxy-2-butanone 4-phosphate synthase (RefSeq) compare
Shew_3305 +0.7 1.7 CaCA family Na(+)/Ca(+) antiporter (RefSeq) compare
Shew_3622 hslO +0.7 4.9 Hsp33-like chaperonin (RefSeq) compare
Shew_2950 +0.7 2.1 RluA family pseudouridine synthase (RefSeq) compare
Shew_1820 prpB +0.7 3.1 2-methylisocitrate lyase (RefSeq) compare
Shew_3628 +0.7 1.5 MgtC/SapB transporter (RefSeq) compare
Shew_0531 +0.7 3.1 DEAD/DEAH box helicase domain-containing protein (RefSeq) compare
Shew_1078 +0.7 3.7 peptidylprolyl isomerase, FKBP-type (RefSeq) compare
Shew_2414 +0.7 1.1 ATP-NAD/AcoX kinase (RefSeq) compare
Shew_2963 +0.7 1.6 hypothetical protein (RefSeq) compare
Shew_2285 +0.7 1.1 UDP-glucose 4-epimerase (RefSeq) compare
Shew_1717 +0.7 1.3 globin (RefSeq) compare
Shew_2504 +0.7 3.3 PpiC-type peptidyl-prolyl cis-trans isomerase (RefSeq) compare
Shew_0615 +0.7 4.8 bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase (RefSeq) compare
Shew_0728 +0.6 5.0 dihydroorotase (RefSeq) compare
Shew_2417 +0.6 3.1 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase (RefSeq) compare
Shew_1563 +0.6 5.0 isocitrate dehydrogenase, NADP-dependent (RefSeq) compare
Shew_3488 +0.6 2.0 ribonuclease PH (RefSeq) compare
Shew_1162 +0.6 1.2 hypothetical protein (RefSeq) compare
Shew_0121 +0.6 1.1 hypothetical protein (RefSeq) compare
Shew_0193 +0.6 1.6 cytochrome c-type biogenesis protein CcmF (RefSeq) compare
Shew_3189 +0.6 2.2 hypothetical protein (RefSeq) compare
Shew_0939 +0.6 5.5 leucyl aminopeptidase (RefSeq) compare
Shew_0568 +0.6 3.9 HflK protein (RefSeq) compare
Shew_0359 fre +0.6 5.3 FMN reductase (RefSeq) compare
Shew_3708 +0.6 3.9 TetR family transcriptional regulator (RefSeq) compare
Shew_0453 +0.6 1.3 response regulator receiver protein (RefSeq) compare
Shew_2667 +0.6 4.4 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ (RefSeq) compare
Shew_0619 +0.6 4.3 adenylate cyclase (RefSeq) compare
Shew_1713 +0.6 2.6 3-oxoacyl-(acyl carrier protein) synthase III (RefSeq) compare
Shew_3176 +0.6 1.5 regulatory protein GntR, HTH (RefSeq) compare
Shew_1011 +0.6 2.3 citrate transporter (RefSeq) compare
Shew_3267 +0.6 3.0 sodium/hydrogen exchanger (RefSeq) compare
Shew_3313 +0.6 1.7 PTS IIA-like nitrogen-regulatory protein PtsN (RefSeq) compare
Shew_2665 +0.6 4.9 beta-ketoacyl synthase (RefSeq) compare
Shew_0214 +0.5 2.1 3-dehydroquinate synthase (RefSeq) compare
Shew_3062 +0.5 4.8 glycine dehydrogenase (RefSeq) compare
Shew_1188 +0.5 2.0 riboflavin synthase subunit alpha (RefSeq) compare
Shew_1931 +0.5 1.2 alkylphosphonate utilization operon protein PhnA (RefSeq) compare
Shew_1302 +0.5 2.3 cytochrome bd ubiquinol oxidase, subunit I (RefSeq) compare
Shew_1411 +0.5 4.5 hexapaptide repeat-containing transferase (RefSeq) compare
Shew_2895 +0.5 2.8 2-dehydropantoate 2-reductase (RefSeq) compare
Shew_1601 +0.5 1.2 3-oxoacyl-(acyl carrier protein) synthase III (RefSeq) compare
Shew_1841 +0.5 1.5 peptidase M48, Ste24p (RefSeq) compare
Shew_2337 tgt +0.5 2.7 queuine tRNA-ribosyltransferase (RefSeq) compare
Shew_3378 +0.5 1.1 Sec-independent protein translocase, TatC subunit (RefSeq) compare
Shew_1186 +0.5 1.4 transcriptional regulator NrdR (RefSeq) compare
Shew_3681 +0.5 3.4 integral membrane sensor signal transduction histidine kinase (RefSeq) compare
Shew_2668 +0.5 3.8 2-nitropropane dioxygenase, NPD (RefSeq) compare
Shew_1438 +0.5 2.3 fumarylacetoacetate (FAA) hydrolase (RefSeq) compare
Shew_1867 +0.5 1.8 hypothetical protein (RefSeq) compare
Shew_2415 +0.5 1.5 major facilitator transporter (RefSeq) compare
Shew_2570 +0.5 4.9 acyl-CoA dehydrogenase domain-containing protein (RefSeq) compare
Shew_1901 +0.5 1.6 hypothetical protein (RefSeq) compare
Shew_3684 +0.5 2.2 binding-protein-dependent transport systems inner membrane component (RefSeq) compare
Shew_0342 +0.5 2.8 hypothetical protein (RefSeq) compare
Shew_1716 +0.5 1.6 3-beta hydroxysteroid dehydrogenase/isomerase (RefSeq) compare
Shew_3548 +0.5 0.7 hypothetical protein (RefSeq) compare
Shew_3197 +0.5 0.7 hypothetical protein (RefSeq) compare
Shew_3498 rpoZ +0.5 2.2 DNA-directed RNA polymerase subunit omega (RefSeq) compare
Shew_1407 +0.5 3.8 short-chain dehydrogenase/reductase SDR (RefSeq) compare
Shew_2074 +0.5 2.0 TonB-dependent receptor (RefSeq) compare
Shew_1810 +0.5 2.4 dihydroorotate dehydrogenase 2 (RefSeq) compare
Shew_2347 +0.5 2.3 phosphonate ABC transporter, periplasmic phosphonate-binding protein (RefSeq) compare
Shew_0315 +0.5 1.7 HemY domain-containing protein (RefSeq) compare
Shew_1882 +0.5 2.0 metal dependent phosphohydrolase (RefSeq) compare
Shew_0570 +0.5 1.0 ubiquinol-cytochrome c reductase, iron-sulfur subunit (RefSeq) compare
Shew_3323 +0.5 1.8 lipase-like (RefSeq) compare
Shew_3395 +0.5 1.0 radical SAM domain-containing protein (RefSeq) compare
Shew_3271 +0.5 2.8 galactokinase (RefSeq) compare
Shew_R0033 +0.5 1.4 tRNA-Arg (RefSeq) compare
Shew_0518 +0.5 2.1 hypothetical protein (RefSeq) compare
Shew_1662 +0.5 1.0 NAD-dependent deacetylase (RefSeq) compare
Shew_2439 +0.5 1.5 RND family efflux transporter MFP subunit (RefSeq) compare
Shew_0775 +0.5 4.0 TetR family transcriptional regulator (RefSeq) compare
Shew_0024 +0.5 0.7 ArsR family transcriptional regulator (RefSeq) compare
Shew_0842 +0.5 2.3 two component LuxR family transcriptional regulator (RefSeq) compare
Shew_2666 +0.5 4.3 omega-3 polyunsaturated fatty acid synthase PfaB (RefSeq) compare
Shew_2656 +0.5 2.9 4'-phosphopantetheinyl transferase (RefSeq) compare
Shew_1500 +0.5 1.2 signal transduction protein (RefSeq) compare
Shew_3312 +0.5 2.3 sigma 54 modulation protein/ribosomal protein S30EA (RefSeq) compare
Shew_2121 +0.5 1.2 diguanylate cyclase (RefSeq) compare
Shew_3266 dipZ +0.5 0.9 thiol:disulfide interchange protein precursor (RefSeq) compare
Shew_3759 +0.5 3.8 imidazolonepropionase (RefSeq) compare
Shew_0854 +0.4 1.8 hypothetical protein (RefSeq) compare
Shew_1961 +0.4 1.8 acyl-CoA dehydrogenase domain-containing protein (RefSeq) compare
Shew_1209 +0.4 2.3 pseudouridylate synthase (RefSeq) compare
Shew_3568 +0.4 2.3 cation diffusion facilitator family transporter (RefSeq) compare
Shew_R0049 +0.4 2.9 tRNA-Pro (RefSeq) compare
Shew_2458 +0.4 0.9 glutathione S-transferase domain-containing protein (RefSeq) compare
Shew_3192 +0.4 2.1 hypothetical protein (RefSeq) compare
Shew_0822 +0.4 1.0 lysine exporter protein LysE/YggA (RefSeq) compare
Shew_3481 +0.4 3.0 DNA repair protein RadC (RefSeq) compare
Shew_2444 +0.4 1.2 hypothetical protein (RefSeq) compare
Shew_1264 +0.4 1.2 UvrD/REP helicase (RefSeq) compare
Shew_0191 +0.4 0.8 cytochrome c, class I (RefSeq) compare
Shew_2509 tig +0.4 3.0 trigger factor (RefSeq) compare
Shew_3682 +0.4 3.0 two component, sigma54 specific, Fis family transcriptional regulator (RefSeq) compare
Shew_1785 +0.4 0.9 band 7 protein (RefSeq) compare
Shew_1313 +0.4 1.3 TetR family transcriptional regulator (RefSeq) compare
Shew_3316 +0.4 2.5 magnesium transporter (RefSeq) compare
Shew_1247 +0.4 1.4 hypothetical protein (RefSeq) compare
Shew_3195 +0.4 1.5 hypothetical protein (RefSeq) compare
Shew_1470 +0.4 3.0 sulfatase (RefSeq) compare
Shew_0650 +0.4 1.7 hypothetical protein (RefSeq) compare
Shew_1669 +0.4 2.2 butyryl-CoA dehydrogenase (RefSeq) compare
Shew_0414 +0.4 3.0 ABC-2 type transporter (RefSeq) compare
Shew_0536 +0.4 2.7 tRNA-dihydrouridine synthase A (RefSeq) compare
Shew_0625 +0.4 3.4 spermidine synthase (RefSeq) compare
Shew_2907 +0.4 0.9 invasion gene expression up-regulator, SirB (RefSeq) compare
Shew_2727 +0.4 3.0 hypothetical protein (RefSeq) compare
Shew_0211 +0.4 1.4 pilus assembly protein, PilQ (RefSeq) compare
Shew_2730 +0.4 1.1 glutathione S-transferase domain-containing protein (RefSeq) compare
Shew_2361 +0.4 0.7 proline racemase (RefSeq) compare
Shew_1978 +0.4 0.8 hypothetical protein (RefSeq) compare
Shew_1620 +0.4 3.0 adenosylmethionine decarboxylase (RefSeq) compare
Shew_2073 +0.4 0.7 lactoylglutathione lyase (RefSeq) compare
Shew_2175 nhaB +0.4 2.6 sodium/proton antiporter (RefSeq) compare
Shew_0827 +0.4 0.8 peptidyl-prolyl cis-trans isomerase, cyclophilin type (RefSeq) compare


Specific Phenotypes

For 1 genes in this experiment

For stress Dimethyl Sulfoxide in Shewanella loihica PV-4

For stress Dimethyl Sulfoxide across organisms