Experiment set5IT063 for Sinorhizobium meliloti 1021

Compare to:

Defined media with L-Histidine

200 most important genes:

  gene name fitness t score description  
SMc01726 -7.8 -5.4 acetylglutamate kinase compare
SMc02123 -7.7 -3.0 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
SMc02245 -7.3 -5.0 dihydroorotate dehydrogenase 2 compare
SMc00235 -7.1 -4.9 anthranilate phosphoribosyltransferase compare
SMc01494 -6.9 -9.4 phosphoserine phosphatase compare
SM_b21175 -6.8 -4.7 phosphate uptake ABC transporter permease compare
SMc03797 -6.5 -9.9 homoserine O-succinyltransferase compare
SMc02766 -6.4 -14.4 tryptophan synthase subunit beta compare
SMc02899 -6.3 -10.6 prephenate dehydratase compare
SMc01843 -6.3 -8.7 5,10-methylenetetrahydrofolate reductase compare
SMc04045 -6.3 -6.1 dihydroxy-acid dehydratase compare
SMc02767 -6.2 -8.5 N-(5'-phosphoribosyl)anthranilate isomerase compare
SMc01801 -6.2 -4.1 N-acetylglutamylphosphate reductase (EC 1.2.1.38) (from data) compare
SMc00236 -6.2 -6.0 Indole-3-glycerol phosphate synthase compare
SMc00640 -6.2 -8.5 phosphoserine aminotransferase compare
SMc01361 -6.1 -4.2 dihydroorotase compare
SMc03070 -6.0 -4.1 glucose-6-phosphate 1-dehydrogenase compare
SMc04405 -5.9 -7.8 3-isopropylmalate dehydrogenase compare
SMc01431 -5.9 -11.9 acetolactate synthase 3 catalytic subunit compare
SMc00092 -5.8 -11.1 phosphoadenosine phosphosulfate reductase compare
SMc03823 -5.8 -11.1 isopropylmalate isomerase large subunit compare
SMc02717 -5.8 -11.1 2-isopropylmalate synthase compare
SM_b21177 -5.7 -3.9 phosphate uptake ABC transporter ATP-binding protein compare
SMc00993 -5.7 -7.7 phosphoribosylamine--glycine ligase compare
SMc00494 -5.6 -2.2 phosphoribosylformylglycinamidine synthase subunit PurS compare
SMc00131 -5.6 -13.5 transcriptional regulator compare
SMc02725 -5.6 -12.5 anthranilate synthase compare
SMc00614 -5.6 -7.6 phosphoribosylglycinamide formyltransferase compare
SMc04028 -5.5 -18.2 glutamate synthase compare
SMc00615 -5.5 -9.6 phosphoribosylaminoimidazole synthetase compare
SMc04002 -5.3 -8.1 phosphoribosylaminoimidazole carboxylase ATPase subunit compare
SMc00815 -5.3 -3.5 inosine 5'-monophosphate dehydrogenase compare
SMc00091 -5.3 -10.7 sulfate adenylyltransferase compare
SMc00412 -5.2 -5.1 orotidine 5'-phosphate decarboxylase compare
SMc03776 -5.2 -3.6 gamma-glutamyl kinase compare
SMc03112 -5.1 -16.1 B12-dependent methionine synthase compare
SMc03777 -5.1 -7.0 gamma-glutamyl phosphate reductase compare
SMc01360 -5.1 -3.5 aspartate carbamoyltransferase catalytic subunit compare
SMc02124 -5.1 -13.5 nitrite reductase compare
SMc00711 -5.0 -4.4 cyclohexadienyl dehydrogenase compare
SMc02165 -5.0 -8.3 orotate phosphoribosyltransferase compare
SMc02217 -5.0 -7.6 O-succinylhomoserine sulfhydrylase compare
SMc00488 -5.0 -16.1 phosphoribosylformylglycinamidine synthase II compare
SMc00293 -5.0 -11.7 homoserine dehydrogenase compare
SMc00554 -5.0 -8.9 amidophosphoribosyltransferase compare
SMc00495 -5.0 -4.8 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
SMc02137 -4.9 -5.8 ornithine carbamoyltransferase compare
SMc02755 -4.9 -7.5 S-adenosyl-L-homocysteine hydrolase compare
SMc02115 -4.9 -1.9 hypothetical protein compare
SMc02765 -4.8 -12.9 tryptophan synthase subunit alpha compare
SMc02166 -4.8 -14.3 dihydroorotase compare
SMc00493 -4.7 -6.4 phosphoribosylformylglycinamidine synthase I compare
SMc01054 -4.7 -5.1 required for sulfate utilization, putative electron source for sulfite reductase CysI (from data) compare
SMc02138 -4.7 -8.1 acetylornithine transaminase compare
SMc04026 -4.7 -8.5 glutamate synthase compare
SMc03826 -4.6 -3.2 argininosuccinate synthase compare
SM_b21176 -4.6 -4.4 phosphate uptake ABC transporter substrate-binding protein precursor compare
SMc03229 -4.5 -2.9 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase compare
SMc00090 -4.5 -10.4 sulfate adenylyltransferase compare
SM_b21174 -4.3 -6.4 phosphate uptake ABC transporter permease compare
SMc01430 -4.3 -6.2 acetolactate synthase 3 regulatory subunit compare
SMc02707 -4.3 -4.6 hypothetical protein compare
SMc01881 -4.3 -2.9 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
SMa1635 -4.3 -2.8 hypothetical protein compare
SMc00641 -4.2 -7.0 D-3-phosphoglycerate dehydrogenase compare
SMc04001 -4.1 -1.6 phosphoribosylaminoimidazole carboxylase catalytic subunit protein compare
SMc04088 -4.1 -8.2 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase compare
SMc03981 -4.1 -4.8 phosphoglycerate kinase compare
SMc01206 -4.0 -3.1 queuine tRNA-ribosyltransferase compare
SMc01053 -3.9 -6.2 siroheme synthase compare
SMc03068 -3.8 -13.2 phosphogluconate dehydratase compare
SMc03763 -3.8 -2.6 cytosine-specific methyltransferase compare
SMc00294 -3.7 -10.0 aminotransferase compare
SMc03978 -3.6 -2.5 transketolase compare
SMc00876 -3.6 -7.9 ATP-binding MRP protein compare
SMc00295 -3.6 -1.8 hypothetical protein compare
SMc03979 -3.6 -2.4 glyceraldehyde-3-phosphate dehydrogenase compare
SMc01569 -3.5 -1.8 carbamoyl phosphate synthase small subunit compare
SMc02058 -3.4 -4.0 YAJC protein compare
SMc03795 -3.3 -1.7 isopropylmalate isomerase small subunit compare
SMc04346 -3.2 -4.4 ketol-acid reductoisomerase compare
SMc00017 -3.2 -1.7 homoserine kinase compare
SMc01770 -3.2 -1.5 serine hydroxymethyltransferase compare
SMc01880 -3.1 -2.1 pantoate--beta-alanine ligase compare
SMc01208 -3.1 -3.9 peptidyl-prolyl cis-trans isomerase B protein compare
SMc01215 -3.1 -2.1 carbamoyl phosphate synthase large subunit compare
SMc01147 -3.0 -4.1 coproporphyrinogen III oxidase compare
SMc02683 -3.0 -3.5 hypothetical protein compare
SMc02835 -3.0 -8.9 glucokinase compare
SMc02246 -3.0 -1.1 hypothetical protein compare
SMc03924 -3.0 -12.5 glycogen synthase compare
SMc01578 -2.9 -14.7 aspartate aminotransferase compare
SMc02425 -2.8 -5.8 transcriptional regulator compare
SMc00492 -2.8 -1.5 hypothetical protein compare
SMc02102 -2.8 -5.8 hypothetical protein compare
SMc01850 -2.8 -3.7 hypothetical protein compare
SMc01441 -2.8 -5.7 membrane bound protease compare
SMc00914 -2.8 -5.4 oxidoreductase compare
SMc02641 -2.6 -5.3 UDP-glucose 6-dehydrogenase compare
SMc02909 -2.6 -2.6 transglycosylase transmembrane protein compare
SMc00419 -2.6 -5.2 glutathione synthetase compare
SMc02582 -2.5 -4.8 hypothetical protein compare
SMc02147 -2.4 -6.4 phosphate regulon sensor histidine kinase transmembrane protein compare
SMc01438 -2.4 -6.6 protease precursor signal peptide protein compare
SMc01440 -2.3 -6.4 hydrolase serine protease transmembrane protein compare
SMc03069 -2.3 -3.1 6-phosphogluconolactonase compare
SMc00673 -2.3 -11.8 Formiminoglutamic iminohydrolase (EC 3.5.3.13) (from data) compare
SMc00838 -2.3 -4.1 hypothetical protein compare
SMa2215 -2.2 -4.2 GntR family transcriptional regulator compare
SMc00334 -2.2 -2.7 cytidylate kinase compare
SMc02753 -2.2 -2.2 PTS system transporter subunit IIA compare
SMc01124 -2.2 -7.3 PII uridylyl-transferase compare
SMc00414 -2.1 -9.0 hypothetical protein compare
SMc02724 -2.1 -3.3 hypothetical protein compare
SMc03242 -2.1 -3.6 GTP-binding protein compare
SMc00619 -2.0 -2.3 hypothetical protein compare
SMc00450 -2.0 -4.2 protoheme IX farnesyltransferase compare
SMc02983 -2.0 -6.7 ornithine, DAP, or arginine decarboxylase compare
SMc01097 -1.9 -6.1 hypothetical protein compare
SMc00987 -1.9 -3.3 hypothetical protein compare
SM_b20048 -1.9 -8.2 transcriptional regulator compare
SMc02850 -1.9 -4.4 DNA polymerase I compare
SMc02140 -1.8 -2.1 phosphate regulon transcriptional regulatory protein compare
SMc03974 -1.8 -6.3 hypothetical protein compare
SMc01183 -1.8 -1.2 LexA repressor compare
SMc04213 -1.8 -2.4 diacylglycerol kinase compare
SMc01939 -1.8 -1.4 urease subunit beta compare
SMc02451 -1.7 -2.2 hypothetical protein compare
SMc01028 -1.7 -9.1 phosphopyruvate hydratase compare
SMc03993 -1.7 -4.0 hypothetical protein compare
SMc00726 -1.6 -1.0 thiol:disulfide interchange redox-active center transmembrane protein compare
SMa1002 -1.6 -2.2 hypothetical protein compare
SM_b21163 -1.6 -9.1 Urocanate hydratase (EC 4.2.1.49) (from data) compare
SMc00709 -1.6 -2.4 hypothetical protein compare
SMa0789 -1.6 -4.3 GntR family transcriptional regulator compare
SMc04330 -1.6 -2.7 trimethylamine methyltransferase compare
SMc00302 -1.6 -3.5 hypothetical protein compare
SMc01845 -1.6 -2.2 transglycosylase transmembrane protein compare
SMc02142 -1.5 -4.5 phosphate transporter ATP-binding protein compare
SMa0734 -1.5 -2.4 hypothetical protein compare
SMc01368 -1.5 -5.2 transport transmembrane protein compare
SMc02362 -1.5 -4.2 cytochrome c-type biogenesis protein CcmE compare
SM_b20903 -1.5 -5.8 sugar uptake ABC transporter permease compare
SM_b20902 -1.5 -9.0 sugar uptake ABC transporter substrate-binding protein precursor compare
SMc02856 -1.5 -7.8 penicillin-binding protein compare
SM_b21153 -1.4 -3.1 acetyltransferase compare
SM_b20540 -1.4 -1.4 hypothetical protein compare
SMc00361 -1.4 -3.7 hypothetical protein compare
SMa1240 -1.4 -1.4 NapF ferredoxin component of periplasmic nitrate reductase compare
SMc04296 -1.4 -1.3 cell division protein FtsZ compare
SMc01595 -1.4 -3.9 sensor histidine kinase transmembrane protein compare
SMc01260 -1.4 -4.0 transcriptional regulator compare
SMc02985 -1.4 -6.0 hypothetical protein compare
SM_b20773 -1.4 -3.8 GntR family transcriptional regulator compare
SMc03046 -1.4 -4.3 transcriptional regulator compare
SMc02227 -1.3 -5.3 fatty oxidation complex enoyl-COA hydratase/3-hydroxyacyl-COA dehydrogenase/3-hydroxybutyryl-COA epimerase compare
SMc00981 -1.3 -7.4 ferredoxin protein compare
SMc00012 -1.3 -1.3 cytochrome C oxidase assembly protein compare
SM_b20302 -1.3 -1.6 hypothetical protein compare
SMc01929 -1.3 -2.5 hypothetical protein compare
SM_b20904 -1.3 -2.8 sugar uptake ABC transporter ATP-binding protein compare
SMc01280 -1.3 -1.1 protease compare
SMc02234 -1.3 -2.2 hypothetical protein compare
SM_b21164 -1.2 -4.2 N-formylglutamate deformylase (EC 3.5.1.68) (from data) compare
SMc02838 -1.2 -5.3 phosphoglyceromutase compare
SMc01842 -1.2 -1.3 methyltransferase transcription regulator protein compare
SMc00556 -1.2 -2.7 DNA repair protein RadA compare
SMc03100 -1.2 -1.1 hypothetical protein compare
SMc03899 -1.2 -1.3 hypothetical protein compare
SM_b21687 -1.2 -1.6 hypothetical protein compare
SM_b20313 -1.2 -3.9 glycerone kinase compare
SMc02055 -1.2 -1.6 phytoene synthase compare
SMc01187 -1.2 -2.2 rare lipoprotein A compare
SMc02407 -1.2 -4.5 hypothetical protein compare
SMc03072 -1.2 -1.6 hypothetical protein compare
SMc02141 -1.2 -3.4 phosphate transporter PhoU compare
SM_b20323 -1.1 -1.0 transcriptional regulator compare
SMc02434 -1.1 -2.5 hypothetical protein compare
SMa1323 -1.1 -1.8 Transcription regulator compare
SMc00982 -1.1 -4.3 dioxygenase compare
SMa1077 -1.1 -2.3 Nex18 symbiotically induced protein compare
SMa0748 -1.1 -1.9 MucR family transcriptional regulator compare
SMc02363 -1.1 -2.3 cytochrome C-type biogenesis transmembrane protein compare
SMc02886 -1.1 -1.9 signal peptide protein compare
SMc02685 -1.1 -3.2 hypothetical protein compare
SMc02543 -1.1 -3.7 hypothetical protein compare
SMc00605 -1.1 -2.1 hypothetical protein compare
SMc00296 -1.1 -5.9 POLY3-hydroxybutyrate polymerase compare
SMc04005 -1.1 -4.3 pyruvate kinase compare
SMc01315 -1.0 -1.2 hypothetical protein compare
SMc01568 -1.0 -1.5 hypothetical protein compare
SMc02143 -1.0 -3.3 phosphate ABC transporter permease compare
SMc00466 -1.0 -2.9 hypothetical protein compare
SM_b21580 -1.0 -1.0 hypothetical protein compare
SMc04348 -1.0 -1.0 transcriptional regulator compare
SMc02697 -1.0 -1.3 hypothetical protein compare
SM_b21165 -1.0 -3.4 Histidine ammonia-lyase (EC 4.3.1.3) (from data) compare
SM_b20086 -1.0 -1.6 hypothetical protein compare
SMc03850 -1.0 -1.1 heme exporter D (cytochrome C-type biogenesis protein) transmembrane compare
SMc00353 -1.0 -1.6 transmembrane protein compare


Specific Phenotypes

For 3 genes in this experiment

For nutrient L-Histidine in Sinorhizobium meliloti 1021

For nutrient L-Histidine across organisms