Experiment set5IT061 for Methanococcus maripaludis S2

200 most important genes:

gene	name	fitness	t score	description
MMP_RS07005		-4.5	-1.6	4Fe-4S binding protein
MMP_RS06700		-3.9	-22.6	hypothetical protein
MMP_RS01175		-3.7	-11.3	triphosphoribosyl-dephospho-CoA synthase
MMP_RS01005		-3.4	-3.3	riboflavin synthase
MMP_RS06680		-3.0	-19.9	Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain
MMP_RS02280		-3.0	-2.7	DUF211 domain-containing protein
MMP_RS06685		-2.9	-17.9	formate dehydrogenase H subunit alpha selenocysteine-containing
MMP_RS03315		-2.9	-2.5	ferrous iron transport protein A
MMP_RS08300		-2.9	-3.5	metal-sulfur cluster assembly factor
MMP_RS04780		-2.9	-6.4	ribonuclease P
MMP_RS08820		-2.8	-10.4	hypothetical protein
MMP_RS06350		-2.7	-10.1	HesA/MoeB/ThiF family protein
MMP_RS03475		-2.6	-1.6	hypothetical protein
MMP_RS06345		-2.6	-16.5	formate dehydrogenase accessory sulfurtransferase FdhD
MMP_RS07635		-2.5	-10.7	MogA/MoaB family molybdenum cofactor biosynthesis protein
MMP_RS06355		-2.5	-5.1	molybdenum cofactor biosynthesis protein MoaE
MMP_RS02235		-2.5	-16.4	CBS domain-containing protein
MMP_RS03015		-2.4	-13.1	GTP 3' 8-cyclase MoaA
MMP_RS05515		-2.4	-8.0	cyclic pyranopterin monophosphate synthase MoaC
MMP_RS06895		-2.4	-4.1	selenocysteine-specific translation elongation factor
MMP_RS02010		-2.4	-12.1	PHP domain-containing protein
MMP_RS05920		-2.3	-1.9	50S ribosomal protein L37e
MMP_RS07845		-2.2	-4.6	LL-diaminopimelate aminotransferase
MMP_RS06715		-2.2	-17.1	cache domain-containing protein
MMP_RS04775		-2.2	-6.4	adenosylhomocysteinase
MMP_RS02195		-2.1	-8.1	tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
MMP_RS08635		-2.1	-4.2	UbiA family prenyltransferase
MMP_RS00895		-2.1	-8.5	hypothetical protein
MMP_RS06295		-2.1	-10.4	methanogenesis marker 14 protein
MMP_RS08745		-2.1	-8.8	CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase
MMP_RS00115		-2.1	-13.4	radical SAM protein
MMP_RS07445		-2.0	-7.7	helix-turn-helix domain-containing protein
MMP_RS01265		-2.0	-6.9	hypothetical protein
MMP_RS01020		-2.0	-2.8	3 4-dihydroxy-2-butanone-4-phosphate synthase
MMP_RS03435		-2.0	-3.5	ketol-acid reductoisomerase
MMP_RS06720		-2.0	-10.3	response regulator transcription factor
MMP_RS07575		-2.0	-9.6	RNA ligase partner protein
MMP_RS03600		-1.9	-3.9	triose-phosphate isomerase
MMP_RS01500		-1.9	-3.7	CBS domain-containing protein
MMP_RS03025		-1.9	-6.2	molybdenum cofactor guanylyltransferase
MMP_RS06705		-1.9	-8.6	formate/nitrite transporter family protein
MMP_RS05875		-1.9	-7.1	hydroxyethylthiazole kinase
MMP_RS04685		-1.9	-5.2	DUF126 domain-containing protein
MMP_RS06400		-1.8	-3.3	4Fe-4S binding protein
MMP_RS04585		-1.8	-9.3	AIR synthase related protein
MMP_RS08460		-1.8	-5.5	proteasome-activating nucleotidase
MMP_RS03400		-1.8	-4.8	archease
MMP_RS00295		-1.7	-5.1	gamma carbonic anhydrase family protein
MMP_RS08210		-1.7	-2.9	phosphatidylglycerophosphatase A
MMP_RS06285		-1.7	-3.2	precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT
MMP_RS00685		-1.7	-5.7	2-phospho-L-lactate guanylyltransferase
MMP_RS03035		-1.6	-4.7	4-hydroxy-tetrahydrodipicolinate synthase
MMP_RS06340		-1.6	-7.9	phosphoadenosine phosphosulfate reductase family protein
MMP_RS01220		-1.6	-7.1	hypothetical protein
MMP_RS08720		-1.6	-2.7	4Fe-4S binding protein
MMP_RS02800		-1.5	-5.6	nucleotidyltransferase domain-containing protein
MMP_RS02135		-1.5	-5.2	DUF5612 domain-containing protein
MMP_RS08790		-1.5	-3.3	translation initiation factor IF-2 subunit alpha
MMP_RS07545		-1.5	-2.7	HTH domain-containing protein
MMP_RS07380		-1.5	-4.2	transcription elongation factor Spt5
MMP_RS02240		-1.5	-5.1	methanogenesis marker 7 protein
MMP_RS07525		-1.5	-9.2	4Fe-4S binding protein
MMP_RS06730		-1.5	-3.8	phosphopantothenate/pantothenate synthetase
MMP_RS02355		-1.4	-2.1	30S ribosomal protein S27ae
MMP_RS01610		-1.4	-4.1	hypothetical protein
MMP_RS00695		-1.4	-1.9	biotin--[acetyl-CoA-carboxylase] ligase
MMP_RS08435		-1.3	-2.2	Era-like GTP-binding protein
MMP_RS00300		-1.3	-1.3	6 7-dimethyl-8-ribityllumazine synthase
MMP_RS06270		-1.3	-4.8	TIGR00300 family protein
MMP_RS00305		-1.3	-2.6	phosphoribosyl-ATP diphosphatase
MMP_RS04890		-1.3	-1.6	adenylyltransferase/cytidyltransferase family protein
MMP_RS00515		-1.3	-1.5	DUF655 domain-containing protein
MMP_RS08645		-1.3	-8.5	UPF0179 family protein
MMP_RS06120		-1.3	-2.9	UPF0147 family protein
MMP_RS01225		-1.2	-6.9	DUF5379 domain-containing protein
MMP_RS03640		-1.2	-4.2	archaeal proteasome endopeptidase complex subunit beta
MMP_RS02190		-1.2	-3.3	sulfopyruvate decarboxylase subunit alpha
MMP_RS06630		-1.2	-1.9	UPF0058 family protein
MMP_RS05555		-1.2	-2.9	DUF4040 domain-containing protein
MMP_RS06475		-1.2	-4.6	FAD-dependent oxidoreductase
MMP_RS01755		-1.2	-2.4	DUF2097 domain-containing protein
MMP_RS01325		-1.2	-3.5	dihydroneopterin aldolase family protein
MMP_RS06315		-1.2	-1.5	cobalt-precorrin-7 (C(5))-methyltransferase
MMP_RS01365		-1.2	-3.6	archaeal proteasome endopeptidase complex subunit alpha
MMP_RS09020		-1.1	-2.4	hypothetical protein
MMP_RS05540		-1.1	-3.6	hypothetical protein
MMP_RS07600		-1.1	-4.4	Ni-sirohydrochlorin a c-diamide synthase
MMP_RS07580		-1.1	-2.3	DUF356 domain-containing protein
MMP_RS07605		-1.1	-3.0	diadenylate cyclase
MMP_RS02340		-1.1	-1.8	DNA-directed RNA polymerase subunit E''
MMP_RS03580		-1.1	-3.2	signal recognition particle-docking protein FtsY
MMP_RS07755		-1.1	-1.9	DUF555 domain-containing protein
MMP_RS06925		-1.1	-2.5	ribonuclease VapC4
MMP_RS07735		-1.1	-1.1	2-ketoisovalerate ferredoxin oxidoreductase subunit alpha
MMP_RS00290		-1.0	-5.3	hypothetical protein
MMP_RS05245		-1.0	-7.2	archaeosine biosynthesis radical SAM protein RaSEA
MMP_RS07765		-1.0	-6.1	sodium:alanine symporter family protein
MMP_RS05430		-1.0	-4.6	TIGR00288 family NYN domain-containing protein
MMP_RS01980		-1.0	-8.7	trimeric intracellular cation channel family protein
MMP_RS07750		-1.0	-3.4	DUF357 domain-containing protein
MMP_RS08715		-1.0	-2.0	formylmethanofuran dehydrogenase subunit B
MMP_RS01380		-1.0	-3.5	PHP domain-containing protein
MMP_RS00110		-1.0	-2.4	hypothetical protein
MMP_RS06105		-1.0	-6.5	hydrogenase maturation peptidase HycI
MMP_RS00320		-1.0	-2.8	class I SAM-dependent methyltransferase
MMP_RS03960		-1.0	-1.2	hypothetical protein
MMP_RS01250		-1.0	-5.4	tRNA (guanine(26)-N(2))-dimethyltransferase
MMP_RS07630		-1.0	-2.1	ATP-binding cassette domain-containing protein
MMP_RS07695		-0.9	-5.5	DUF3236 domain-containing protein
MMP_RS06865		-0.9	-1.9	HypC/HybG/HupF family hydrogenase formation chaperone
MMP_RS00060		-0.9	-1.5	3-dehydroquinate synthase II
MMP_RS06020		-0.9	-3.9	archaeoflavoprotein AfpA
MMP_RS06625		-0.9	-1.1	DNA primase
MMP_RS03555		-0.9	-6.6	transcriptional regulator
MMP_RS02165		-0.9	-5.5	tRNA-dihydrouridine synthase
MMP_RS01385		-0.9	-1.0	imidazole glycerol phosphate synthase subunit HisH
MMP_RS01985		-0.9	-4.4	F420-dependent methylenetetrahydromethanopterin dehydrogenase
MMP_RS05445		-0.9	-5.8	CoB--CoM heterodisulfide reductase subunit B
MMP_RS03155		-0.9	-5.6	precorrin-6A reductase
MMP_RS07200		-0.9	-3.7	[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
MMP_RS03445		-0.9	-1.5	methanogenesis marker 17 protein
MMP_RS02345		-0.8	-2.7	GTP-dependent dephospho-CoA kinase family protein
MMP_RS05765		-0.8	-4.6	M42 family metallopeptidase
MMP_RS07730		-0.8	-2.3	pyruvate synthase subunit beta
MMP_RS01830		-0.8	-1.7	tRNA-Val
MMP_RS02875		-0.8	-5.1	chorismate pyruvate-lyase family protein
MMP_RS04870		-0.8	-3.4	TIGR02253 family HAD-type hydrolase
MMP_RS05510		-0.8	-4.7	Rrf2 family transcriptional regulator
MMP_RS05815		-0.8	-2.5	NOL1/NOP2/sun family putative RNA methylase
MMP_RS02885		-0.8	-6.4	molybdopterin biosynthesis protein
MMP_RS07390		-0.8	-2.5	cell division protein FtsZ
MMP_RS06975		-0.8	-2.7	sulfide-dependent adenosine diphosphate thiazole synthase
MMP_RS08200		-0.8	-6.6	archaeosine synthase subunit alpha
MMP_RS05545		-0.8	-3.9	pyridoxal phosphate-dependent aminotransferase
MMP_RS05550		-0.8	-1.0	cation:proton antiporter
MMP_RS03385		-0.8	-1.5	cation diffusion facilitator family transporter
MMP_RS01795		-0.8	-2.1	methanogenesis marker 6 protein
MMP_RS06230		-0.8	-2.3	helix-turn-helix domain-containing protein
MMP_RS08320		-0.8	-3.7	molybdopterin molybdotransferase MoeA
MMP_RS00315		-0.7	-3.6	Nif3-like dinuclear metal center hexameric protein
MMP_RS01800		-0.7	-3.7	TIGR00303 family protein
MMP_RS02245		-0.7	-2.7	hypothetical protein
MMP_RS05345		-0.7	-4.0	hypothetical protein
MMP_RS05450		-0.7	-3.9	CoB--CoM heterodisulfide reductase subunit C
MMP_RS06930		-0.7	-5.3	MBL fold metallo-hydrolase
MMP_RS07385		-0.7	-1.2	protein translocase SEC61 complex subunit gamma
MMP_RS04615		-0.7	-3.8	PDGLE domain-containing protein
MMP_RS07365		-0.7	-5.4	2-phosphoglycerate kinase
MMP_RS02145		-0.7	-3.7	winged helix-turn-helix transcriptional regulator
MMP_RS00620		-0.7	-5.4	4Fe-4S binding protein
MMP_RS04850		-0.7	-5.9	UPF0254 family protein
MMP_RS08165		-0.7	-2.5	phosphoglycerate dehydrogenase
MMP_RS07535		-0.7	-4.6	4Fe-4S binding protein
MMP_RS07700		-0.7	-4.1	DUF1188 domain-containing protein
MMP_RS00725		-0.6	-3.6	5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC
MMP_RS05070		-0.6	-4.7	4Fe-4S dicluster domain-containing protein
MMP_RS07435		-0.6	-1.8	GMP synthase subunit A
MMP_RS04605		-0.6	-3.8	cobalt ECF transporter T component CbiQ
MMP_RS06200		-0.6	-4.2	M24 family metallopeptidase
MMP_RS06940		-0.6	-2.2	polyprenyl diphosphate synthase
MMP_RS05060		-0.6	-4.7	AAA family ATPase
MMP_RS06395		-0.6	-3.3	ThiF family adenylyltransferase
MMP_RS07425		-0.6	-2.6	GTP-binding protein
MMP_RS08330		-0.6	-3.1	NADH-quinone oxidoreductase subunit H
MMP_RS07685		-0.6	-3.2	TIGR01212 family radical SAM protein
MMP_RS00050		-0.6	-3.9	AarF/UbiB family protein
MMP_RS06175		-0.6	-3.2	winged helix-turn-helix transcriptional regulator
MMP_RS07190		-0.6	-4.2	chromosome segregation protein SMC
MMP_RS01195		-0.6	-1.5	metalloregulator ArsR/SmtB family transcription factor
MMP_RS08650		-0.6	-2.1	glutamine--fructose-6-phosphate transaminase (isomerizing)
MMP_RS06215		-0.6	-1.7	30S ribosomal protein S6e
MMP_RS01725		-0.6	-2.7	class I SAM-dependent methyltransferase family protein
MMP_RS03095		-0.6	-3.0	diphthine synthase
MMP_RS00120		-0.6	-3.5	LysR family transcriptional regulator
MMP_RS07355		-0.6	-1.0	transcription factor S
MMP_RS08360		-0.6	-2.1	hypothetical protein
MMP_RS00130		-0.6	-1.1	nickel-responsive transcriptional regulator NikR
MMP_RS01720		-0.6	-0.9	replication factor C large subunit
MMP_RS01840		-0.6	-3.5	TIGR00289 family protein
MMP_RS08915		-0.6	-1.7	2 5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase
MMP_RS04620		-0.6	-3.9	cobalt transporter CbiM
MMP_RS03220		-0.5	-2.7	RNA 2' 3'-cyclic phosphodiesterase
MMP_RS03470		-0.5	-4.0	phosphoadenosine phosphosulfate reductase family protein
MMP_RS00985		-0.5	-2.6	CDC48 family AAA ATPase
MMP_RS06885		-0.5	-1.5	50S ribosome-binding GTPase
MMP_RS05100		-0.5	-4.7	CO dehydrogenase/acetyl-CoA synthase complex subunit alpha
MMP_RS00735		-0.5	-2.3	5 10-methenyltetrahydromethanopterin hydrogenase
MMP_RS07530		-0.5	-4.4	4Fe-4S binding protein
MMP_RS00915		-0.5	-2.2	DUF116 domain-containing protein
MMP_RS08445		-0.5	-1.9	DUF2099 family protein
MMP_RS06855		-0.5	-4.0	hypothetical protein
MMP_RS01780		-0.5	-3.3	TrmJ/YjtD family RNA methyltransferase
MMP_RS00810		-0.5	-2.7	topoisomerase DNA-binding C4 zinc finger domain-containing protein
MMP_RS03685		-0.5	-3.4	Mrp/NBP35 family ATP-binding protein
MMP_RS04690		-0.5	-1.5	class III signal peptide-containing protein
MMP_RS08070		-0.5	-3.2	DUF2096 domain-containing protein
MMP_RS00720		-0.5	-3.3	metal-dependent hydrolase
MMP_RS09025		-0.5	-1.1	hypothetical protein
MMP_RS01030		-0.5	-1.7	MTAP family purine nucleoside phosphorylase
MMP_RS05800		-0.5	-3.8	B12-binding domain-containing radical SAM protein

Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments