Experiment set5IT060 for Shewanella loihica PV-4

Compare to:

LB with Bacitracin 0.25 mg/ml

200 most detrimental genes:

  gene name fitness t score description  
Shew_3273 +5.3 32.3 hypothetical protein (RefSeq) compare
Shew_0763 +4.9 9.6 putative PAS/PAC sensor protein (RefSeq) compare
Shew_1809 +4.9 31.8 NAD-glutamate dehydrogenase (RefSeq) compare
Shew_2049 +4.9 23.5 DNA-binding transcriptional regulator HexR (RefSeq) compare
Shew_2572 +4.8 21.9 enoyl-CoA hydratase/isomerase (RefSeq) compare
Shew_3430 +4.8 8.5 pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase (RefSeq) compare
Shew_1298 guaA +4.7 38.7 bifunctional GMP synthase/glutamine amidotransferase protein (RefSeq) compare
Shew_0459 +4.7 18.8 PAS/PAC sensor hybrid histidine kinase (RefSeq) compare
Shew_3560 +4.7 27.5 signal transduction histidine kinase, nitrogen specific, NtrB (RefSeq) compare
Shew_1425 +4.6 16.9 adenylyl-sulfate kinase (RefSeq) compare
Shew_3561 +4.6 23.7 nitrogen metabolism transcriptional regulator, NtrC, Fis family (RefSeq) compare
Shew_2382 +4.3 33.9 cysteine synthase A (RefSeq) compare
Shew_0867 +4.3 6.4 malate dehydrogenase (RefSeq) compare
Shew_0296 +4.2 6.1 heat shock protein Hsp20 (RefSeq) compare
Shew_2637 +4.2 17.3 PII uridylyl-transferase (RefSeq) compare
Shew_2502 +4.1 17.2 ABC transporter-related protein (RefSeq) compare
Shew_3431 aceE +4.1 31.8 pyruvate dehydrogenase subunit E1 (RefSeq) compare
Shew_3432 pdhR +4.0 13.1 transcriptional regulator PdhR (RefSeq) compare
Shew_1013 +3.9 34.9 aspartate carbamoyltransferase (RefSeq) compare
Shew_1657 sucC +3.8 7.5 succinyl-CoA synthetase subunit beta (RefSeq) compare
Shew_0777 +3.8 7.0 two-component response regulator (RefSeq) compare
Shew_1301 +3.8 33.4 phosphoribosylformylglycinamidine synthase (RefSeq) compare
Shew_2000 +3.7 4.5 glyceraldehyde-3-phosphate dehydrogenase (RefSeq) compare
Shew_1227 +3.7 7.5 glutamate--cysteine ligase (RefSeq) compare
Shew_1819 +3.7 11.2 GntR family transcriptional regulator (RefSeq) compare
Shew_0618 +3.6 5.8 hypothetical protein (RefSeq) compare
Shew_3266 dipZ +3.5 6.3 thiol:disulfide interchange protein precursor (RefSeq) compare
Shew_0755 +3.5 13.1 fructose-1,6-bisphosphate aldolase (RefSeq) compare
Shew_1563 +3.5 26.1 isocitrate dehydrogenase, NADP-dependent (RefSeq) compare
Shew_0728 +3.5 28.2 dihydroorotase (RefSeq) compare
Shew_3487 pyrE +3.4 16.4 orotate phosphoribosyltransferase (RefSeq) compare
Shew_2498 +3.3 4.8 extracellular solute-binding protein (RefSeq) compare
Shew_2320 +3.3 20.4 RNA methyltransferase (RefSeq) compare
Shew_1224 +3.3 20.9 sodium:dicarboxylate symporter (RefSeq) compare
Shew_2086 +3.3 8.1 hypothetical protein (RefSeq) compare
Shew_3065 +3.2 24.3 UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase (RefSeq) compare
Shew_3554 glnA +3.2 6.9 glutamine synthetase (RefSeq) compare
Shew_1402 +3.2 23.6 glucose-1-phosphate thymidylyltransferase (RefSeq) compare
Shew_1128 +3.2 24.6 LysR family transcriptional regulator (RefSeq) compare
Shew_1810 +3.1 15.2 dihydroorotate dehydrogenase 2 (RefSeq) compare
Shew_1512 +3.1 13.4 phosphoribosylglycinamide formyltransferase (RefSeq) compare
Shew_0359 fre +3.1 23.2 FMN reductase (RefSeq) compare
Shew_2812 deoD +3.1 12.6 purine nucleoside phosphorylase (RefSeq) compare
Shew_2087 +3.1 9.2 hypothetical protein (RefSeq) compare
Shew_2838 carB +2.9 20.6 carbamoyl phosphate synthase large subunit (RefSeq) compare
Shew_3729 +2.9 4.7 coproporphyrinogen III oxidase (RefSeq) compare
Shew_2839 +2.9 23.3 carbamoyl phosphate synthase small subunit (RefSeq) compare
Shew_0570 +2.9 5.2 ubiquinol-cytochrome c reductase, iron-sulfur subunit (RefSeq) compare
Shew_0326 +2.9 12.5 HAD family hydrolase (RefSeq) compare
Shew_0086 +2.8 25.3 electron-transferring-flavoproteindehydrogenase (RefSeq) compare
Shew_2302 +2.8 19.9 amidophosphoribosyltransferase (RefSeq) compare
Shew_2813 +2.8 6.4 phosphopentomutase (RefSeq) compare
Shew_3488 +2.8 4.5 ribonuclease PH (RefSeq) compare
Shew_0571 +2.8 8.0 cytochrome b/b6 domain-containing protein (RefSeq) compare
Shew_1050 +2.8 8.3 sigma E regulatory protein, MucB/RseB (RefSeq) compare
Shew_2584 +2.8 22.7 electron transfer flavoprotein beta-subunit (RefSeq) compare
Shew_0585 +2.8 7.9 cAMP-regulatory protein (RefSeq) compare
Shew_3709 +2.7 22.7 2-amino-3-ketobutyrate coenzyme A ligase (RefSeq) compare
Shew_3295 +2.7 13.7 AFG1 family ATPase (RefSeq) compare
Shew_0193 +2.7 9.8 cytochrome c-type biogenesis protein CcmF (RefSeq) compare
Shew_0470 +2.7 5.1 MATE efflux family protein (RefSeq) compare
Shew_3710 tdh +2.7 12.9 L-threonine 3-dehydrogenase (RefSeq) compare
Shew_3499 +2.6 10.9 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (RefSeq) compare
Shew_3413 +2.6 16.1 phosphoribosylamine--glycine ligase (RefSeq) compare
Shew_1401 +2.6 13.9 dTDP-glucose 4,6 dehydratase (RefSeq) compare
Shew_1011 +2.5 11.2 citrate transporter (RefSeq) compare
Shew_3412 purH +2.5 16.2 bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (RefSeq) compare
Shew_1927 +2.5 4.2 dihydrolipoamide acetyltransferase (RefSeq) compare
Shew_1341 +2.5 6.1 anti-sigma-28 factor, FlgM (RefSeq) compare
Shew_3440 +2.5 3.7 prepilin peptidase (RefSeq) compare
Shew_1405 +2.5 15.4 glycosyl transferase, group 1 (RefSeq) compare
Shew_2141 +2.4 8.4 lytic murein transglycosylase (RefSeq) compare
Shew_1559 +2.4 2.4 hypothetical protein (RefSeq) compare
Shew_3664 +2.4 15.7 alpha-L-glutamate ligase (RefSeq) compare
Shew_2481 +2.4 12.2 porin (RefSeq) compare
Shew_1437 +2.4 17.6 transcriptional regulator, TyrR (RefSeq) compare
Shew_3378 +2.3 3.7 Sec-independent protein translocase, TatC subunit (RefSeq) compare
Shew_3500 +2.3 5.3 putative endoribonuclease L-PSP (RefSeq) compare
Shew_1188 +2.3 5.8 riboflavin synthase subunit alpha (RefSeq) compare
Shew_0022 +2.3 14.5 TrkH family potassium uptake protein (RefSeq) compare
Shew_1922 +2.2 9.1 phosphoglucomutase (RefSeq) compare
Shew_1822 +2.2 9.3 aconitate hydratase (RefSeq) compare
Shew_3225 +2.2 12.3 glutathione synthetase (RefSeq) compare
Shew_2814 deoA +2.1 4.4 thymidine phosphorylase (RefSeq) compare
Shew_3377 +2.1 1.8 twin-arginine translocation protein, TatB subunit (RefSeq) compare
Shew_1820 prpB +2.1 3.2 2-methylisocitrate lyase (RefSeq) compare
Shew_1382 +2.1 4.3 cobyrinic acid a,c-diamide synthase (RefSeq) compare
Shew_0330 +2.1 1.3 nifR3 family TIM-barrel protein (RefSeq) compare
Shew_1189 +2.0 16.2 3,4-dihydroxy-2-butanone 4-phosphate synthase (RefSeq) compare
Shew_1210 +2.0 6.5 stationary-phase survival protein SurE (RefSeq) compare
Shew_1985 +2.0 6.9 cytochrome c oxidase, cbb3-type, subunit I (RefSeq) compare
Shew_1625 +2.0 5.1 L-serine dehydratase 1 (RefSeq) compare
Shew_2571 +2.0 15.0 propionyl-CoA carboxylase (RefSeq) compare
Shew_1992 +2.0 10.1 hypothetical protein (RefSeq) compare
Shew_1601 +2.0 3.3 3-oxoacyl-(acyl carrier protein) synthase III (RefSeq) compare
Shew_2770 +2.0 2.0 polyprenyl synthetase (RefSeq) compare
Shew_2008 +2.0 1.4 short-chain dehydrogenase/reductase SDR (RefSeq) compare
Shew_0421 +2.0 1.4 phage shock protein C, PspC (RefSeq) compare
Shew_3621 +2.0 1.4 RNA-binding S4 domain-containing protein (RefSeq) compare
Shew_2895 +1.9 10.1 2-dehydropantoate 2-reductase (RefSeq) compare
Shew_2573 +1.9 14.2 carbamoyl-phosphate synthase L chain, ATP-binding (RefSeq) compare
Shew_1230 +1.9 3.2 phosphoribosylaminoimidazole carboxylase, catalytic subunit (RefSeq) compare
Shew_3374 +1.9 5.1 hypothetical protein (RefSeq) compare
Shew_2434 +1.9 4.5 hypothetical protein (RefSeq) compare
Shew_2025 +1.9 11.2 leucine-responsive transcriptional regulator (RefSeq) compare
Shew_1925 +1.9 9.5 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) (RefSeq) compare
Shew_1185 glyA +1.8 9.6 serine hydroxymethyltransferase (RefSeq) compare
Shew_1926 +1.8 4.5 transketolase, central region (RefSeq) compare
Shew_2837 +1.8 1.6 transcription elongation factor GreA (RefSeq) compare
Shew_3189 +1.8 4.5 hypothetical protein (RefSeq) compare
Shew_1990 +1.8 4.5 heavy metal translocating P-type ATPase (RefSeq) compare
Shew_0775 +1.8 9.4 TetR family transcriptional regulator (RefSeq) compare
Shew_1951 +1.8 8.7 aromatic amino acid aminotransferase (RefSeq) compare
Shew_2385 +1.8 9.6 TonB-dependent receptor, plug (RefSeq) compare
Shew_1092 +1.8 11.5 amino acid carrier protein (RefSeq) compare
Shew_0320 +1.7 5.2 frataxin family protein (RefSeq) compare
Shew_1302 +1.7 6.8 cytochrome bd ubiquinol oxidase, subunit I (RefSeq) compare
Shew_2365 +1.7 2.6 GntR family transcriptional regulator (RefSeq) compare
Shew_1667 +1.7 4.1 acetyl-CoA acetyltransferase (RefSeq) compare
Shew_1673 fabG +1.6 3.2 3-ketoacyl-(acyl-carrier-protein) reductase (RefSeq) compare
Shew_2414 +1.6 1.8 ATP-NAD/AcoX kinase (RefSeq) compare
Shew_0614 +1.6 4.7 cysteine/glutathione ABC transporter membrane/ATP-binding component (RefSeq) compare
Shew_0191 +1.6 2.0 cytochrome c, class I (RefSeq) compare
Shew_3759 +1.6 12.6 imidazolonepropionase (RefSeq) compare
Shew_2841 +1.6 6.5 peptidylprolyl isomerase, FKBP-type (RefSeq) compare
Shew_1865 +1.6 9.3 phosphoenolpyruvate-protein phosphotransferase (RefSeq) compare
Shew_0613 +1.5 6.8 cysteine/glutathione ABC transporter membrane/ATP-binding component (RefSeq) compare
Shew_0304 +1.5 4.3 hypothetical protein (RefSeq) compare
Shew_1006 +1.5 1.9 ErfK/YbiS/YcfS/YnhG family protein (RefSeq) compare
Shew_2496 +1.5 3.2 phage shock protein A, PspA (RefSeq) compare
Shew_1823 +1.5 3.5 putative AcnD-accessory protein PrpF (RefSeq) compare
Shew_1574 +1.5 6.0 ATP-binding Mrp/Nbp35 family protein (RefSeq) compare
Shew_0942 +1.5 10.2 RDD domain-containing protein (RefSeq) compare
Shew_1439 +1.5 8.6 maleylacetoacetate isomerase (RefSeq) compare
Shew_1987 +1.4 5.8 Cbb3-type cytochrome oxidase component (RefSeq) compare
Shew_1411 +1.4 8.8 hexapaptide repeat-containing transferase (RefSeq) compare
Shew_3548 +1.4 1.4 hypothetical protein (RefSeq) compare
Shew_1398 +1.4 4.5 NusG antitermination factor (RefSeq) compare
Shew_2347 +1.4 4.6 phosphonate ABC transporter, periplasmic phosphonate-binding protein (RefSeq) compare
Shew_2558 +1.4 1.3 1,4-dihydroxy-2-naphthoate octaprenyltransferase (RefSeq) compare
Shew_3271 +1.4 7.9 galactokinase (RefSeq) compare
Shew_1036 +1.4 9.2 putative adenylate/guanylate cyclase (RefSeq) compare
Shew_1602 +1.3 2.6 malonyl CoA-acyl carrier protein transacylase (RefSeq) compare
Shew_3312 +1.3 5.1 sigma 54 modulation protein/ribosomal protein S30EA (RefSeq) compare
Shew_0534 +1.3 3.2 major facilitator transporter (RefSeq) compare
Shew_1403 +1.3 9.2 dTDP-4-dehydrorhamnose reductase (RefSeq) compare
Shew_3622 hslO +1.3 7.9 Hsp33-like chaperonin (RefSeq) compare
Shew_3711 +1.3 1.2 rhodanese domain-containing protein (RefSeq) compare
Shew_0580 +1.3 2.5 succinylglutamic semialdehyde dehydrogenase (RefSeq) compare
Shew_2219 +1.3 6.2 hypothetical protein (RefSeq) compare
Shew_1186 +1.2 2.2 transcriptional regulator NrdR (RefSeq) compare
Shew_0615 +1.2 6.8 bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase (RefSeq) compare
Shew_2962 +1.2 2.9 malate dehydrogenase (RefSeq) compare
Shew_0220 +1.2 5.4 phosphoglycolate phosphatase (RefSeq) compare
Shew_0281 +1.2 5.8 phospholipid/glycerol acyltransferase (RefSeq) compare
Shew_1859 +1.2 1.3 carbonate dehydratase (RefSeq) compare
Shew_3313 +1.2 2.5 PTS IIA-like nitrogen-regulatory protein PtsN (RefSeq) compare
Shew_1500 +1.2 1.9 signal transduction protein (RefSeq) compare
Shew_1417 +1.2 4.5 undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase (RefSeq) compare
Shew_2285 +1.2 1.1 UDP-glucose 4-epimerase (RefSeq) compare
Shew_3628 +1.1 1.1 MgtC/SapB transporter (RefSeq) compare
Shew_2419 +1.1 8.1 phosphohistidine phosphatase, SixA (RefSeq) compare
Shew_3708 +1.1 7.7 TetR family transcriptional regulator (RefSeq) compare
Shew_1058 +1.1 5.4 holo-acyl-carrier-protein synthase (RefSeq) compare
Shew_3727 +1.1 6.4 shikimate 5-dehydrogenase (RefSeq) compare
Shew_1287 +1.1 1.6 hypothetical protein (RefSeq) compare
Shew_1575 +1.1 5.3 uridine kinase (RefSeq) compare
Shew_1798 +1.1 4.0 paraquat-inducible protein A (RefSeq) compare
Shew_0531 +1.1 2.3 DEAD/DEAH box helicase domain-containing protein (RefSeq) compare
Shew_2759 +1.1 5.3 peptidase S9 prolyl oligopeptidase (RefSeq) compare
Shew_3197 +1.0 1.0 hypothetical protein (RefSeq) compare
Shew_1920 +1.0 4.6 alpha/beta hydrolase fold (RefSeq) compare
Shew_1564 +1.0 2.4 cold-shock DNA-binding domain-containing protein (RefSeq) compare
Shew_3209 +1.0 1.5 nitrate reductase cytochrome c-type subunit (NapB) (RefSeq) compare
Shew_1372 fliL +1.0 3.3 flagellar basal body-associated protein FliL (RefSeq) compare
Shew_1555 +1.0 2.1 Glu/Leu/Phe/Val dehydrogenase, dimerisation region (RefSeq) compare
Shew_1577 +1.0 1.2 aminotransferase, class IV (RefSeq) compare
Shew_1122 +1.0 2.5 hypothetical protein (RefSeq) compare
Shew_0799 +1.0 1.7 MarR family transcriptional regulator (RefSeq) compare
Shew_3568 +1.0 5.1 cation diffusion facilitator family transporter (RefSeq) compare
Shew_1796 +1.0 1.9 hypothetical protein (RefSeq) compare
Shew_0767 +1.0 3.6 ATP-dependent RNA helicase SrmB (RefSeq) compare
Shew_2361 +1.0 1.2 proline racemase (RefSeq) compare
Shew_3260 +1.0 4.3 porin (RefSeq) compare
Shew_2570 +1.0 7.7 acyl-CoA dehydrogenase domain-containing protein (RefSeq) compare
Shew_0214 +1.0 2.1 3-dehydroquinate synthase (RefSeq) compare
Shew_1889 +0.9 6.4 alpha amylase, catalytic region (RefSeq) compare
Shew_2897 +0.9 4.8 LysR family transcriptional regulator (RefSeq) compare
Shew_2815 +0.9 1.6 deoxyribose-phosphate aldolase (RefSeq) compare
Shew_1669 +0.9 2.5 butyryl-CoA dehydrogenase (RefSeq) compare
Shew_0438 +0.9 1.1 GumN family protein (RefSeq) compare
Shew_3686 +0.9 6.2 molybdopterin-guanine dinucleotide biosynthesis protein A (RefSeq) compare
Shew_1214 +0.9 6.1 DNA mismatch repair protein (RefSeq) compare
Shew_2277 +0.9 1.5 DoxX family protein (RefSeq) compare
Shew_0342 +0.9 4.1 hypothetical protein (RefSeq) compare
Shew_0268 +0.9 0.9 transcriptional antiterminator, Rof (RefSeq) compare
Shew_2786 +0.9 1.6 sterol-binding domain-containing protein (RefSeq) compare
Shew_1209 +0.9 3.1 pseudouridylate synthase (RefSeq) compare
Shew_1404 +0.9 5.2 dTDP-4-dehydrorhamnose 3,5-epimerase (RefSeq) compare
Shew_2963 +0.9 1.0 hypothetical protein (RefSeq) compare


Specific Phenotypes

For 9 genes in this experiment

For stress Bacitracin in Shewanella loihica PV-4

For stress Bacitracin across organisms