Experiment set5IT060 for Methanococcus maripaludis S2

Compare to:

H2 McCas- cells incubated with 5000 ng DNA (pDNA pLW40neo) then transferred and grown in liquid medium with neomycin

200 most important genes:

  gene name fitness t score description  
MMP_RS03960 -2.7 -1.2 hypothetical protein compare
MMP_RS01195 -2.3 -1.4 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS07815 -2.2 -1.4 DUF2120 domain-containing protein compare
MMP_RS03440 -2.2 -1.4 MoaD/ThiS family protein compare
MMP_RS03485 -2.2 -2.4 TIGR00267 family protein compare
MMP_RS06975 -2.2 -1.5 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS08360 -2.2 -3.2 hypothetical protein compare
MMP_RS02010 -2.1 -5.7 PHP domain-containing protein compare
MMP_RS07355 -2.0 -0.9 transcription factor S compare
MMP_RS01525 -2.0 -1.2 nucleoside-diphosphate kinase compare
MMP_RS02280 -1.9 -0.8 DUF211 domain-containing protein compare
MMP_RS04605 -1.9 -2.9 cobalt ECF transporter T component CbiQ compare
MMP_RS06340 -1.8 -3.6 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS02135 -1.7 -1.6 DUF5612 domain-containing protein compare
MMP_RS03390 -1.6 -2.9 malate dehydrogenase compare
MMP_RS01440 -1.6 -3.7 NAAT family transporter compare
MMP_RS05835 -1.5 -0.7 secondary thiamine-phosphate synthase enzyme YjbQ compare
MMP_RS00735 -1.5 -1.2 5 10-methenyltetrahydromethanopterin hydrogenase compare
MMP_RS01720 -1.5 -1.7 replication factor C large subunit compare
MMP_RS06840 -1.4 -0.9 DNA-directed RNA polymerase subunit N compare
MMP_RS06325 -1.4 -1.4 hypothetical protein compare
MMP_RS08500 -1.4 -2.0 pyridoxal 5'-phosphate synthase glutaminase subunit PdxT compare
MMP_RS05550 -1.4 -0.6 cation:proton antiporter compare
MMP_RS01840 -1.4 -3.8 TIGR00289 family protein compare
MMP_RS06555 -1.4 -1.9 cupin domain-containing protein compare
MMP_RS08350 -1.4 -0.8 hypothetical protein compare
MMP_RS01385 -1.3 -0.6 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS03450 -1.3 -1.5 glycine synthesis protein GlyXS (from data) compare
MMP_RS08785 -1.3 -0.8 RNA-protein complex protein Nop10 compare
MMP_RS03465 -1.3 -0.8 adenine phosphoribosyltransferase compare
MMP_RS06395 -1.2 -1.6 ThiF family adenylyltransferase compare
MMP_RS00675 -1.2 -0.8 nitroreductase family protein compare
MMP_RS03475 -1.2 -0.5 hypothetical protein compare
MMP_RS08340 -1.2 -1.8 4Fe-4S binding protein compare
MMP_RS01830 -1.2 -1.0 tRNA-Val compare
MMP_RS07750 -1.2 -1.8 DUF357 domain-containing protein compare
MMP_RS02605 -1.2 -0.7 MotA/TolQ/ExbB proton channel family protein compare
MMP_RS03445 -1.1 -0.7 methanogenesis marker 17 protein compare
MMP_RS01020 -1.1 -0.8 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS01445 -1.0 -3.3 hypothetical protein compare
MMP_RS07525 -1.0 -3.2 4Fe-4S binding protein compare
MMP_RS00110 -1.0 -1.0 hypothetical protein compare
MMP_RS06285 -1.0 -1.0 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS02835 -1.0 -2.2 CGGC domain-containing protein compare
MMP_RS07955 -1.0 -1.4 FumA C-terminus/TtdB family hydratase beta subunit compare
MMP_RS01865 -1.0 -0.9 GPR1/FUN34/YaaH family transporter compare
MMP_RS08370 -1.0 -0.4 cation:proton antiporter subunit C compare
MMP_RS02490 -1.0 -1.4 hypothetical protein compare
MMP_RS05920 -0.9 -0.4 50S ribosomal protein L37e compare
MMP_RS06885 -0.9 -0.6 50S ribosome-binding GTPase compare
MMP_RS08090 -0.9 -2.1 hypothetical protein compare
MMP_RS06105 -0.9 -2.5 hydrogenase maturation peptidase HycI compare
MMP_RS03220 -0.9 -1.4 RNA 2' 3'-cyclic phosphodiesterase compare
MMP_RS01765 -0.9 -3.1 HIT family protein compare
MMP_RS05865 -0.9 -2.2 hypothetical protein compare
MMP_RS05765 -0.9 -2.2 M42 family metallopeptidase compare
MMP_RS07540 -0.9 -1.6 CBS domain-containing protein compare
MMP_RS01225 -0.9 -1.4 DUF5379 domain-containing protein compare
MMP_RS01610 -0.8 -0.8 hypothetical protein compare
MMP_RS08445 -0.8 -1.6 DUF2099 family protein compare
MMP_RS03095 -0.8 -2.1 diphthine synthase compare
MMP_RS07365 -0.8 -3.2 2-phosphoglycerate kinase compare
MMP_RS01150 -0.8 -1.6 aldo/keto reductase compare
MMP_RS04185 -0.8 -4.0 aldo/keto reductase compare
MMP_RS06130 -0.8 -1.2 peptidylprolyl isomerase compare
MMP_RS04100 -0.8 -1.9 hypothetical protein compare
MMP_RS06865 -0.7 -1.6 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS05795 -0.7 -1.9 redox-regulated ATPase YchF compare
MMP_RS00880 -0.7 -1.4 ribosome assembly RNA-binding protein YhbY compare
MMP_RS06350 -0.7 -1.3 HesA/MoeB/ThiF family protein compare
MMP_RS07635 -0.7 -1.0 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS05555 -0.7 -0.6 DUF4040 domain-containing protein compare
MMP_RS07630 -0.7 -0.7 ATP-binding cassette domain-containing protein compare
MMP_RS06585 -0.7 -1.0 DMT family protein compare
MMP_RS05425 -0.7 -1.4 monovalent cation/H+ antiporter complex subunit F compare
MMP_RS00395 -0.7 -0.9 MGMT family protein compare
MMP_RS06445 -0.7 -2.3 DUF89 domain-containing protein compare
MMP_RS08215 -0.7 -1.3 DUF483 domain-containing protein compare
MMP_RS00740 -0.7 -1.2 cyclase family protein compare
MMP_RS02110 -0.7 -0.9 hypothetical protein compare
MMP_RS08335 -0.7 -2.0 NADH-quinone oxidoreductase subunit B family protein compare
MMP_RS01645 -0.7 -1.6 SWIM zinc finger family protein compare
MMP_RS02595 -0.7 -0.8 putative zinc-binding protein compare
MMP_RS03965 -0.7 -1.2 hypothetical protein compare
MMP_RS00455 -0.7 -3.0 orotate phosphoribosyltransferase-like protein compare
MMP_RS04985 -0.7 -1.9 DUF2180 family protein compare
MMP_RS07605 -0.6 -0.8 diadenylate cyclase compare
MMP_RS01075 -0.6 -1.0 hypothetical protein compare
MMP_RS08760 -0.6 -1.5 hypothetical protein compare
MMP_RS01370 -0.6 -2.7 acetate--CoA ligase family protein compare
MMP_RS08415 -0.6 -1.4 radical SAM protein compare
MMP_RS05515 -0.6 -1.2 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS02940 -0.6 -2.7 TatD family hydrolase compare
MMP_RS08330 -0.6 -1.3 NADH-quinone oxidoreductase subunit H compare
MMP_RS00130 -0.6 -0.3 nickel-responsive transcriptional regulator NikR compare
MMP_RS04040 -0.6 -2.5 hypothetical protein compare
MMP_RS06530 -0.6 -1.9 bifunctional hexulose-6-phosphate synthase/ribonuclease regulator compare
MMP_RS04290 -0.6 -2.9 4Fe-4S binding protein compare
MMP_RS03400 -0.6 -0.6 archease compare
MMP_RS03955 -0.6 -3.3 DUF3578 domain-containing protein compare
MMP_RS04255 -0.6 -1.8 coenzyme F420 hydrogenase subunit beta compare
MMP_RS04055 -0.6 -0.8 hypothetical protein compare
MMP_RS07575 -0.6 -0.9 RNA ligase partner protein compare
MMP_RS01220 -0.6 -1.5 hypothetical protein compare
MMP_RS05505 -0.6 -2.4 class IV adenylate cyclase compare
MMP_RS08455 -0.6 -1.2 multiprotein bridging factor aMBF1 compare
MMP_RS06200 -0.6 -2.9 M24 family metallopeptidase compare
MMP_RS04420 -0.6 -1.4 LysE family translocator compare
MMP_RS01650 -0.6 -0.4 sulfurtransferase TusA family protein compare
MMP_RS03895 -0.6 -1.2 hypothetical protein compare
MMP_RS05065 -0.6 -1.3 CooT family nickel-binding protein compare
MMP_RS00430 -0.6 -1.8 hypothetical protein compare
MMP_RS06365 -0.6 -0.8 hypothetical protein compare
MMP_RS00965 -0.5 -1.4 hypothetical protein compare
MMP_RS01325 -0.5 -0.6 dihydroneopterin aldolase family protein compare
MMP_RS03145 -0.5 -1.3 fibrillarin-like rRNA/tRNA 2'-O-methyltransferase compare
MMP_RS05355 -0.5 -0.4 hypothetical protein compare
MMP_RS01500 -0.5 -0.4 CBS domain-containing protein compare
MMP_RS00895 -0.5 -0.5 hypothetical protein compare
MMP_RS01095 -0.5 -1.9 iron ABC transporter permease compare
MMP_RS07350 -0.5 -0.7 preprotein translocase subunit Sec61beta compare
MMP_RS09055 -0.5 -0.4 CAP domain-containing protein compare
MMP_RS05090 -0.5 -2.4 CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta compare
MMP_RS05095 -0.5 -1.5 CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon compare
MMP_RS04035 -0.5 -0.9 hypothetical protein compare
MMP_RS04875 -0.5 -1.4 energy-converting hydrogenase B subunit P compare
MMP_RS02735 -0.5 -1.1 MBL fold metallo-hydrolase compare
MMP_RS08240 -0.5 -1.7 methanogenesis marker 16 metalloprotein compare
MMP_RS00545 -0.5 -1.1 XRE family transcriptional regulator compare
MMP_RS05950 -0.5 -2.1 nickel-dependent hydrogenase large subunit compare
MMP_RS05850 -0.5 -1.3 Ldh family oxidoreductase compare
MMP_RS01435 -0.5 -1.5 DMT family transporter compare
MMP_RS03125 -0.5 -1.5 cell division ATPase MinD compare
MMP_RS01985 -0.5 -1.0 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS07710 -0.5 -1.9 cell division protein FtsZ compare
MMP_RS00905 -0.5 -1.4 phenylacetate--CoA ligase compare
MMP_RS05155 -0.5 -1.4 hypothetical protein compare
MMP_RS05540 -0.5 -1.3 hypothetical protein compare
MMP_RS05440 -0.5 -2.0 winged helix-turn-helix transcriptional regulator compare
MMP_RS00960 -0.5 -1.0 iron export ABC transporter permease subunit FetB compare
MMP_RS05720 -0.5 -1.4 signal recognition particle subunit SRP19/SEC65 family protein compare
MMP_RS04595 -0.5 -1.9 hypothetical protein compare
MMP_RS04190 -0.4 -1.6 hypothetical protein compare
MMP_RS08980 -0.4 -1.2 hypothetical protein compare
MMP_RS01335 -0.4 -0.8 prefoldin subunit beta compare
MMP_RS01210 -0.4 -1.7 sodium:solute symporter compare
MMP_RS02930 -0.4 -0.6 class I SAM-dependent methyltransferase compare
MMP_RS02915 -0.4 -1.5 amino acid ABC transporter permease compare
MMP_RS02610 -0.4 -1.3 DUF2162 domain-containing protein compare
MMP_RS04250 -0.4 -1.9 PC4/YdbC family ssDNA-binding protein compare
MMP_RS04795 -0.4 -1.8 tRNA (pseudouridine(54)-N(1))-methyltransferase TrmY compare
MMP_RS06270 -0.4 -0.7 TIGR00300 family protein compare
MMP_RS07695 -0.4 -1.2 DUF3236 domain-containing protein compare
MMP_RS01570 -0.4 -0.4 hypothetical protein compare
MMP_RS04415 -0.4 -2.2 peptide-methionine (S)-S-oxide reductase MsrA compare
MMP_RS06500 -0.4 -1.8 ATP-binding protein compare
MMP_RS04475 -0.4 -1.2 nitrogen fixation compare
MMP_RS05125 -0.4 -2.3 D-aminoacyl-tRNA deacylase compare
MMP_RS08345 -0.4 -1.8 4Fe-4S binding protein compare
MMP_RS08310 -0.4 -0.6 TMEM165/GDT1 family protein compare
MMP_RS02165 -0.4 -1.5 tRNA-dihydrouridine synthase compare
MMP_RS01045 -0.4 -1.3 diphthamide biosynthesis enzyme Dph2 compare
MMP_RS06315 -0.4 -0.2 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS05970 -0.4 -0.9 class II SORL domain-containing protein compare
MMP_RS05945 -0.4 -1.1 CBS domain-containing protein compare
MMP_RS01725 -0.4 -0.7 class I SAM-dependent methyltransferase family protein compare
MMP_RS08640 -0.4 -2.2 TIM barrel protein compare
MMP_RS07415 -0.4 -1.8 molybdopterin-guanine dinucleotide biosynthesis protein MobB compare
MMP_RS05955 -0.4 -0.3 CoB--CoM heterodisulfide reductase subunit C compare
MMP_RS01655 -0.4 -0.8 DsrE family protein compare
MMP_RS02630 -0.4 -1.9 rubredoxin compare
MMP_RS06190 -0.4 -1.9 tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO compare
MMP_RS05285 -0.4 -1.1 MMPL family transporter compare
MMP_RS08365 -0.4 -0.8 energy conserving hydrogenase EhbF compare
MMP_RS01660 -0.4 -1.0 hypothetical protein compare
MMP_RS02300 -0.4 -0.9 NAD(P)H-dependent oxidoreductase compare
MMP_RS04150 -0.4 -1.6 MFS transporter compare
MMP_RS07435 -0.4 -0.3 GMP synthase subunit A compare
MMP_RS08235 -0.4 -1.1 hypothetical protein compare
MMP_RS02760 -0.4 -2.4 COG1361 S-layer family protein compare
MMP_RS02560 -0.4 -2.0 DUF2283 domain-containing protein compare
MMP_RS04315 -0.4 -1.9 corrinoid protein compare
MMP_RS04105 -0.4 -1.3 MarR family transcriptional regulator compare
MMP_RS02390 -0.4 -1.1 NifB/NifX family molybdenum-iron cluster-binding protein compare
MMP_RS02230 -0.4 -1.6 sodium-dependent transporter compare
MMP_RS07535 -0.4 -1.6 4Fe-4S binding protein compare
MMP_RS00400 -0.4 -1.6 tributyrin esterase compare
MMP_RS06520 -0.4 -1.5 DUF1786 domain-containing protein compare
MMP_RS08075 -0.4 -1.1 DUF749 domain-containing protein compare
MMP_RS04220 -0.4 -1.7 queuosine precursor transporter compare
MMP_RS06355 -0.4 -0.5 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS05960 -0.4 -2.2 CoB--CoM heterodisulfide reductase subunit B compare
MMP_RS03300 -0.4 -0.3 TOBE domain-containing protein compare
MMP_RS00945 -0.4 -0.3 PadR family transcriptional regulator compare
MMP_RS00040 -0.4 -0.9 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS01055 -0.4 -1.2 hypothetical protein compare
MMP_RS03225 -0.3 -1.1 acetolactate decarboxylase compare
MMP_RS01870 -0.3 -1.8 acyl-CoA dehydratase activase compare
MMP_RS07545 -0.3 -0.3 HTH domain-containing protein compare
MMP_RS07425 -0.3 -0.9 GTP-binding protein compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in natural competence experiments

For natural competence Neomycin trisulfate salt hydrate across organisms