Experiment set5IT060 for Klebsiella michiganensis M5al

Compare to:

D-Alanine carbon source

200 most important genes:

  gene name fitness t score description  
BWI76_RS01655 -8.2 -5.7 homoserine O-succinyltransferase compare
BWI76_RS20355 -8.0 -4.7 colicin V production protein compare
BWI76_RS18950 -7.5 -4.9 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS00990 -7.5 -5.2 ketol-acid reductoisomerase compare
BWI76_RS04670 -7.5 -5.2 3-isopropylmalate dehydratase large subunit compare
BWI76_RS11850 -7.1 -8.5 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS04645 -6.9 -4.8 3-dehydroquinase compare
BWI76_RS00850 -6.9 -5.7 acetylglutamate kinase compare
BWI76_RS03415 -6.9 -5.8 LacI family transcriptional regulator compare
BWI76_RS04245 -6.8 -8.1 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS04675 -6.7 -6.5 3-isopropylmalate dehydrogenase compare
BWI76_RS18920 -6.6 -4.4 ATP phosphoribosyltransferase compare
BWI76_RS08205 -6.6 -6.4 DNA-binding transcriptional dual regulator NagC compare
BWI76_RS11855 -6.5 -7.7 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS04250 -6.3 -7.5 homoserine kinase compare
BWI76_RS20965 -6.3 -4.1 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS23920 -6.3 -4.2 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS04160 -6.2 -7.4 phosphoserine phosphatase compare
BWI76_RS09755 -6.2 -6.9 phosphoserine transaminase compare
BWI76_RS23220 -6.2 -7.3 amino-acid N-acetyltransferase compare
BWI76_RS02815 -6.2 -3.6 fructose-bisphosphatase class I compare
BWI76_RS05015 -6.1 -4.1 transcriptional regulator compare
BWI76_RS05835 -6.1 -4.0 gamma-glutamyl-phosphate reductase compare
BWI76_RS01615 -6.0 -10.1 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS18940 -6.0 -6.7 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS18935 -5.9 -7.9 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS00785 -5.8 -4.0 cystathionine gamma-synthase compare
BWI76_RS08385 -5.7 -2.9 citrate (Si)-synthase compare
BWI76_RS27475 -5.7 -7.9 regulatory protein GntR family protein compare
BWI76_RS21265 -5.7 -10.5 phosphoribosylformylglycinamidine synthase compare
BWI76_RS23360 -5.7 -3.5 diaminopimelate decarboxylase compare
BWI76_RS04665 -5.6 -19.0 3-isopropylmalate dehydratase small subunit compare
BWI76_RS00835 -5.6 -13.5 phosphoenolpyruvate carboxylase compare
BWI76_RS17735 -5.6 -5.4 D-amino acid dehydrogenase small subunit conserved
BWI76_RS26460 -5.6 -6.5 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS10990 -5.5 -2.9 dihydroorotase compare
BWI76_RS05840 -5.5 -6.5 glutamate 5-kinase compare
BWI76_RS25420 -5.3 -6.4 malate dehydrogenase compare
BWI76_RS09910 -5.3 -18.3 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS26085 -5.3 -3.1 3-dehydroquinate synthase compare
BWI76_RS09760 -5.3 -5.2 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS22240 -5.2 -6.4 transcriptional regulator compare
BWI76_RS04685 -5.2 -8.4 putative leucine operon leader peptide compare
BWI76_RS04255 -5.2 -10.4 threonine synthase compare
BWI76_RS21475 -5.2 -5.2 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS00855 -5.1 -7.8 argininosuccinate lyase compare
BWI76_RS04470 -5.1 -9.2 carbamoyl phosphate synthase large subunit compare
BWI76_RS09645 -5.0 -1.7 thioredoxin-disulfide reductase compare
BWI76_RS20350 -5.0 -4.3 amidophosphoribosyltransferase compare
BWI76_RS04680 -5.0 -11.9 2-isopropylmalate synthase compare
BWI76_RS26570 -4.8 -3.3 anion permease compare
BWI76_RS18955 -4.8 -4.2 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS27385 -4.8 -7.3 orotate phosphoribosyltransferase compare
BWI76_RS21465 -4.8 -4.6 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS00845 -4.8 -8.5 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS06800 -4.7 -1.6 DUF2496 domain-containing protein compare
BWI76_RS04705 -4.7 -7.1 DNA-binding transcriptional regulator FruR compare
BWI76_RS18925 -4.7 -3.5 histidinol dehydrogenase compare
BWI76_RS11860 -4.6 -6.2 anthranilate synthase component I compare
BWI76_RS20895 -4.6 -4.3 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS00805 -4.6 -2.8 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS01610 -4.5 -5.8 phosphoribosylamine--glycine ligase compare
BWI76_RS00980 -4.5 -11.6 PLP-dependent threonine dehydratase compare
BWI76_RS03080 -4.5 -4.3 (Fe-S)-cluster assembly protein compare
BWI76_RS03010 -4.4 -7.1 ornithine carbamoyltransferase compare
BWI76_RS00140 -4.4 -1.5 phosphate transport system regulator PhoU compare
BWI76_RS07065 -4.4 -5.1 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS11840 -4.4 -4.9 tryptophan synthase subunit alpha compare
BWI76_RS02700 -4.4 -7.1 D-serine/D-alanine/glycine transporter conserved
BWI76_RS17065 -4.3 -9.2 phosphoenolpyruvate synthase compare
BWI76_RS09635 -4.3 -4.0 amino acid ABC transporter ATP-binding protein compare
BWI76_RS24285 -4.3 -6.8 cystathionine beta-lyase compare
BWI76_RS00975 -4.2 -6.6 dihydroxy-acid dehydratase compare
BWI76_RS27170 -4.2 -4.6 MltR family transcriptional regulator compare
BWI76_RS25115 -4.2 -5.3 argininosuccinate synthase compare
BWI76_RS11845 -4.2 -2.4 tryptophan synthase subunit beta compare
BWI76_RS18930 -4.0 -3.4 histidinol-phosphate transaminase compare
BWI76_RS24900 -4.0 -2.7 DeoR family transcriptional regulator compare
BWI76_RS07070 -4.0 -5.0 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS08210 -4.0 -1.9 N-acetylglucosamine-6-phosphate deacetylase compare
BWI76_RS23365 -3.9 -4.6 LysR family transcriptional regulator compare
BWI76_RS11965 -3.9 -3.2 orotidine-5'-phosphate decarboxylase compare
BWI76_RS09660 -3.8 -2.6 DNA translocase FtsK compare
BWI76_RS20270 -3.8 -5.6 hypothetical protein compare
BWI76_RS04465 -3.8 -4.4 carbamoyl-phosphate synthase small subunit compare
BWI76_RS04240 -3.7 -2.2 thr operon leader peptide compare
BWI76_RS02610 -3.7 -5.1 transcriptional regulator compare
BWI76_RS23885 -3.7 -1.7 2-octaprenylphenol hydroxylase compare
BWI76_RS20435 -3.7 -1.8 chorismate synthase compare
BWI76_RS09640 -3.7 -4.3 cysteine/glutathione ABC transporter permease/ATP-binding protein CydD compare
BWI76_RS06485 -3.7 -2.2 cytochrome o ubiquinol oxidase subunit III compare
BWI76_RS08520 -3.6 -2.7 colicin transporter TolQ compare
BWI76_RS26175 -3.6 -5.4 DeoR/GlpR family transcriptional regulator compare
BWI76_RS20995 -3.6 -4.3 RNA degradosome polyphosphate kinase compare
BWI76_RS22765 -3.5 -8.0 sulfite reductase subunit alpha compare
BWI76_RS21070 -3.5 -2.7 outer membrane protein assembly factor BamB compare
BWI76_RS05120 -3.5 -5.9 bifunctional glycosyl transferase/transpeptidase compare
BWI76_RS23240 -3.4 -3.3 exonuclease V subunit gamma compare
BWI76_RS21675 -3.4 -1.6 hypothetical protein compare
BWI76_RS02995 -3.4 -3.6 aspartate carbamoyltransferase compare
BWI76_RS22760 -3.3 -9.1 sulfite reductase subunit beta compare
BWI76_RS00400 -3.3 -1.8 glutamine synthetase compare
BWI76_RS01800 -3.3 -4.9 glucose-6-phosphate isomerase compare
BWI76_RS15825 -3.2 -3.4 hypothetical protein compare
BWI76_RS22755 -3.2 -6.3 phosphoadenosine phosphosulfate reductase compare
BWI76_RS27430 -3.2 -1.5 (p)ppGpp synthetase compare
BWI76_RS08535 -3.2 -2.9 translocation protein TolB compare
BWI76_RS26455 -3.2 -3.0 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
BWI76_RS27820 -3.2 -1.4 ilvB operon leader peptide IvbL compare
BWI76_RS06525 -3.1 -3.8 ATP-dependent Clp protease proteolytic subunit compare
BWI76_RS22690 -3.1 -4.2 adenylyl-sulfate kinase compare
BWI76_RS05200 -3.1 -3.6 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS19375 -3.1 -2.8 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase compare
BWI76_RS08530 -3.0 -2.8 protein TolA compare
BWI76_RS02580 -3.0 -2.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase compare
BWI76_RS19705 -3.0 -4.9 kinase compare
BWI76_RS08395 -3.0 -2.2 succinate dehydrogenase cytochrome b556 large subunit compare
BWI76_RS06475 -3.0 -1.4 protoheme IX farnesyltransferase compare
BWI76_RS06185 -2.9 -6.5 shikimate kinase II compare
BWI76_RS23230 -2.8 -3.3 exodeoxyribonuclease V subunit beta compare
BWI76_RS20650 -2.8 -1.9 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS00985 -2.8 -3.9 transcriptional regulator IlvY compare
BWI76_RS05680 -2.7 -2.4 LacI family transcriptional regulator compare
BWI76_RS25600 -2.7 -1.3 tRNA-Thr compare
BWI76_RS01185 -2.7 -2.6 adenylate cyclase compare
BWI76_RS20150 -2.6 -1.3 NADH:ubiquinone oxidoreductase subunit J compare
BWI76_RS07675 -2.6 -3.3 DeoR family transcriptional regulator compare
BWI76_RS12090 -2.6 -1.8 HNH endonuclease compare
BWI76_RS06490 -2.5 -3.8 cytochrome ubiquinol oxidase subunit I compare
BWI76_RS02970 -2.5 -3.6 trehalose operon repressor compare
BWI76_RS08405 -2.5 -3.0 succinate dehydrogenase flavoprotein subunit compare
BWI76_RS11155 -2.5 -2.6 penicillin-binding protein activator LpoB compare
BWI76_RS15060 -2.5 -3.2 MarR family transcriptional regulator compare
BWI76_RS00345 -2.5 -3.3 protein disulfide oxidoreductase DsbA compare
BWI76_RS20160 -2.5 -3.2 NADH-quinone oxidoreductase subunit H compare
BWI76_RS26075 -2.4 -4.3 DNA adenine methylase compare
BWI76_RS01110 -2.3 -4.7 TDP-fucosamine acetyltransferase compare
BWI76_RS01095 -2.3 -2.8 UDP-N-acetyl-D-mannosamine dehydrogenase compare
BWI76_RS02735 -2.3 -3.4 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS20155 -2.3 -2.2 NADH-quinone oxidoreductase subunit I compare
BWI76_RS19730 -2.3 -4.6 1-phosphofructokinase compare
BWI76_RS21165 -2.3 -2.0 Fe-S cluster assembly transcriptional regulator IscR compare
BWI76_RS08525 -2.3 -3.3 colicin transporter compare
BWI76_RS23420 -2.2 -6.3 LacI family transcriptional regulator compare
BWI76_RS25280 -2.2 -1.9 RNase adaptor protein RapZ compare
BWI76_RS09615 -2.2 -2.4 ATP-dependent Clp protease ATP-binding subunit ClpA compare
BWI76_RS07120 -2.2 -7.1 LacI family transcriptional regulator compare
BWI76_RS07435 -2.2 -4.8 LacI family transcriptional regulator compare
BWI76_RS02745 -2.2 -1.4 hypothetical protein compare
BWI76_RS23355 -2.2 -3.7 LacI family transcriptional regulator compare
BWI76_RS20135 -2.1 -3.0 NADH-quinone oxidoreductase subunit M compare
BWI76_RS26940 -2.1 -6.8 transcriptional regulator compare
BWI76_RS08430 -2.1 -3.9 succinate--CoA ligase subunit alpha compare
BWI76_RS13575 -2.1 -2.5 sugar binding transcriptional regulator, LacI family protein compare
BWI76_RS06495 -2.1 -5.4 cytochrome ubiquinol oxidase subunit II compare
BWI76_RS27075 -2.1 -4.8 IclR family transcriptional regulator compare
BWI76_RS08390 -2.1 -3.0 hypothetical protein compare
BWI76_RS04510 -2.1 -1.5 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) compare
BWI76_RS03225 -2.1 -6.7 transcriptional regulator compare
BWI76_RS11610 -2.0 -2.9 glutamate dehydrogenase compare
BWI76_RS08425 -2.0 -4.9 succinyl-CoA ligase subunit beta compare
BWI76_RS24850 -2.0 -4.4 DeoR family transcriptional regulator compare
BWI76_RS02985 -2.0 -3.5 reactive intermediate/imine deaminase compare
BWI76_RS27440 -1.9 -3.5 DNA helicase RecG compare
BWI76_RS20140 -1.9 -3.8 NADH-quinone oxidoreductase subunit L compare
BWI76_RS11040 -1.9 -3.6 ribonuclease E compare
BWI76_RS20180 -1.9 -4.3 NADH-quinone oxidoreductase subunit C/D compare
BWI76_RS27390 -1.9 -1.7 ribonuclease PH compare
BWI76_RS03040 -1.9 -1.7 leucyl aminopeptidase compare
BWI76_RS01210 -1.9 -1.3 tyrosine recombinase XerC compare
BWI76_RS03880 -1.9 -2.6 homoprotocatechuate degradation operon regulator, HpaR compare
BWI76_RS01885 -1.9 -1.4 CsbD family protein compare
BWI76_RS15135 -1.9 -3.5 hypothetical protein compare
BWI76_RS16235 -1.9 -4.2 membrane protein compare
BWI76_RS20190 -1.9 -4.2 NADH-quinone oxidoreductase subunit A compare
BWI76_RS26620 -1.9 -1.2 Fe-S biogenesis protein NfuA compare
BWI76_RS26310 -1.9 -6.8 IclR family transcriptional regulator compare
BWI76_RS20170 -1.8 -2.9 NADH-quinone oxidoreductase subunit F compare
BWI76_RS25960 -1.8 -3.1 NUDIX hydrolase compare
BWI76_RS20440 -1.8 -2.0 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS02410 -1.8 -2.1 EF-P beta-lysylation protein EpmB compare
BWI76_RS21505 -1.8 -1.2 hypothetical protein compare
BWI76_RS19495 -1.8 -1.4 ABC transporter, quaternary amine uptake transporter (QAT) family, ATP-binding protein compare
BWI76_RS00065 -1.8 -4.5 MurR/RpiR family transcriptional regulator compare
BWI76_RS25645 -1.8 -4.1 shikimate dehydrogenase compare
BWI76_RS04530 -1.8 -1.7 peptidylprolyl isomerase SurA compare
BWI76_RS17720 -1.8 -1.5 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS01125 -1.7 -2.9 4-alpha-L-fucosyltransferase compare
BWI76_RS26055 -1.7 -3.9 siroheme synthase compare
BWI76_RS25485 -1.7 -1.4 septum formation protein Maf compare
BWI76_RS00600 -1.7 -3.7 LacI family transcriptional regulator compare
BWI76_RS07305 -1.7 -4.7 sucrose operon repressor compare
BWI76_RS26685 -1.7 -4.9 glutathione-disulfide reductase compare
BWI76_RS07725 -1.6 -1.3 iron-enterobactin transporter permease compare
BWI76_RS09520 -1.6 -1.8 arginine ABC transporter ATP-binding protein ArtP compare
BWI76_RS01115 -1.6 -3.4 dTDP-4-amino-4,6-dideoxygalactose transaminase compare
BWI76_RS03665 -1.6 -1.6 ABC transporter ATP-binding protein compare
BWI76_RS23480 -1.6 -7.3 EAL domain-containing protein compare
BWI76_RS01350 -1.5 -0.9 NAD(P)H-flavin reductase compare
BWI76_RS00965 -1.5 -1.1 acetolactate synthase 2 small subunit compare


Specific Phenotypes

For 6 genes in this experiment

For carbon source D-Alanine in Klebsiella michiganensis M5al

For carbon source D-Alanine across organisms