Experiment set5IT059 for Methanococcus maripaludis S2

Compare to:

H2 McCas- cells grown in liquid medium with neomycin

200 most important genes:

  gene name fitness t score description  
MMP_RS00675 -3.4 -1.3 nitroreductase family protein compare
MMP_RS07355 -2.8 -1.0 transcription factor S compare
MMP_RS02010 -2.7 -8.8 PHP domain-containing protein compare
MMP_RS03475 -2.1 -0.8 hypothetical protein compare
MMP_RS08435 -2.0 -1.9 Era-like GTP-binding protein compare
MMP_RS03485 -2.0 -3.1 TIGR00267 family protein compare
MMP_RS08340 -1.9 -3.5 4Fe-4S binding protein compare
MMP_RS07630 -1.9 -1.6 ATP-binding cassette domain-containing protein compare
MMP_RS07545 -1.8 -0.9 HTH domain-containing protein compare
MMP_RS05920 -1.8 -0.6 50S ribosomal protein L37e compare
MMP_RS08370 -1.7 -0.6 cation:proton antiporter subunit C compare
MMP_RS00900 -1.7 -2.1 50S ribosomal protein L39e compare
MMP_RS01225 -1.7 -2.8 DUF5379 domain-containing protein compare
MMP_RS06525 -1.7 -1.3 YciI family protein compare
MMP_RS01020 -1.6 -1.2 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS05555 -1.6 -1.2 DUF4040 domain-containing protein compare
MMP_RS08350 -1.6 -1.0 hypothetical protein compare
MMP_RS02280 -1.5 -0.8 DUF211 domain-containing protein compare
MMP_RS00685 -1.5 -1.4 2-phospho-L-lactate guanylyltransferase compare
MMP_RS06730 -1.5 -1.0 phosphopantothenate/pantothenate synthetase compare
MMP_RS08440 -1.4 -1.9 cell division protein SepF compare
MMP_RS05425 -1.3 -2.9 monovalent cation/H+ antiporter complex subunit F compare
MMP_RS06840 -1.3 -0.9 DNA-directed RNA polymerase subunit N compare
MMP_RS02900 -1.2 -0.4 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS06315 -1.2 -0.6 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS06900 -1.2 -1.7 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS02175 -1.2 -0.6 DUF1611 domain-containing protein compare
MMP_RS08500 -1.2 -3.7 pyridoxal 5'-phosphate synthase glutaminase subunit PdxT compare
MMP_RS06340 -1.1 -3.6 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS01440 -1.1 -3.7 NAAT family transporter compare
MMP_RS01220 -1.1 -3.1 hypothetical protein compare
MMP_RS05265 -1.1 -1.0 2-isopropylmalate synthase compare
MMP_RS01960 -1.1 -0.5 hypothetical protein compare
MMP_RS03095 -1.1 -3.7 diphthine synthase compare
MMP_RS06270 -1.1 -2.3 TIGR00300 family protein compare
MMP_RS03440 -1.1 -1.1 MoaD/ThiS family protein compare
MMP_RS05550 -1.0 -0.5 cation:proton antiporter compare
MMP_RS07845 -1.0 -1.2 LL-diaminopimelate aminotransferase compare
MMP_RS06120 -1.0 -0.7 UPF0147 family protein compare
MMP_RS05865 -1.0 -2.9 hypothetical protein compare
MMP_RS04775 -1.0 -1.5 adenosylhomocysteinase compare
MMP_RS07750 -1.0 -2.2 DUF357 domain-containing protein compare
MMP_RS01720 -1.0 -1.3 replication factor C large subunit compare
MMP_RS08445 -1.0 -2.0 DUF2099 family protein compare
MMP_RS00750 -1.0 -1.3 fumarate hydratase compare
MMP_RS05515 -1.0 -3.3 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS06350 -1.0 -2.9 HesA/MoeB/ThiF family protein compare
MMP_RS08335 -0.9 -3.2 NADH-quinone oxidoreductase subunit B family protein compare
MMP_RS05460 -0.9 -3.7 YcaO-related McrA-glycine thioamidation protein compare
MMP_RS01385 -0.9 -0.4 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS04685 -0.9 -1.2 DUF126 domain-containing protein compare
MMP_RS08360 -0.9 -2.1 hypothetical protein compare
MMP_RS06975 -0.9 -1.1 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS01335 -0.9 -1.5 prefoldin subunit beta compare
MMP_RS07365 -0.8 -4.3 2-phosphoglycerate kinase compare
MMP_RS07435 -0.8 -0.7 GMP synthase subunit A compare
MMP_RS03110 -0.8 -2.1 glycosyltransferase family 2 protein compare
MMP_RS03300 -0.8 -0.7 TOBE domain-containing protein compare
MMP_RS08165 -0.8 -2.0 phosphoglycerate dehydrogenase compare
MMP_RS06540 -0.8 -1.2 3-methyl-2-oxobutanoate dehydrogenase subunit VorB compare
MMP_RS06905 -0.8 -1.4 hypothetical protein compare
MMP_RS03435 -0.8 -0.5 ketol-acid reductoisomerase compare
MMP_RS03155 -0.8 -2.3 precorrin-6A reductase compare
MMP_RS05355 -0.8 -0.6 hypothetical protein compare
MMP_RS08725 -0.8 -1.7 Ni/Fe hydrogenase subunit alpha compare
MMP_RS01085 -0.8 -1.3 hypothetical protein compare
MMP_RS07815 -0.8 -0.8 DUF2120 domain-containing protein compare
MMP_RS06895 -0.7 -0.9 selenocysteine-specific translation elongation factor compare
MMP_RS04605 -0.7 -1.3 cobalt ECF transporter T component CbiQ compare
MMP_RS08240 -0.7 -3.2 methanogenesis marker 16 metalloprotein compare
MMP_RS08365 -0.7 -1.9 energy conserving hydrogenase EhbF compare
MMP_RS05965 -0.7 -2.4 carboxymuconolactone decarboxylase family protein compare
MMP_RS05765 -0.7 -2.0 M42 family metallopeptidase compare
MMP_RS08915 -0.7 -1.6 2 5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase compare
MMP_RS02805 -0.7 -0.7 HEPN domain-containing protein compare
MMP_RS01325 -0.7 -1.2 dihydroneopterin aldolase family protein compare
MMP_RS02875 -0.7 -3.4 chorismate pyruvate-lyase family protein compare
MMP_RS02605 -0.7 -0.5 MotA/TolQ/ExbB proton channel family protein compare
MMP_RS02720 -0.7 -1.2 molybdate ABC transporter substrate-binding protein compare
MMP_RS04195 -0.7 -2.1 flavodoxin compare
MMP_RS03390 -0.7 -2.9 malate dehydrogenase compare
MMP_RS06325 -0.7 -1.0 hypothetical protein compare
MMP_RS06370 -0.7 -2.1 biotin synthase BioB compare
MMP_RS01265 -0.7 -1.1 hypothetical protein compare
MMP_RS07540 -0.7 -1.6 CBS domain-containing protein compare
MMP_RS05440 -0.7 -3.6 winged helix-turn-helix transcriptional regulator compare
MMP_RS08760 -0.7 -1.5 hypothetical protein compare
MMP_RS06105 -0.7 -2.5 hydrogenase maturation peptidase HycI compare
MMP_RS08330 -0.7 -2.1 NADH-quinone oxidoreductase subunit H compare
MMP_RS01075 -0.7 -0.7 hypothetical protein compare
MMP_RS02265 -0.6 -1.6 nitroreductase family protein compare
MMP_RS00110 -0.6 -0.8 hypothetical protein compare
MMP_RS01830 -0.6 -0.8 tRNA-Val compare
MMP_RS07955 -0.6 -1.7 FumA C-terminus/TtdB family hydratase beta subunit compare
MMP_RS08345 -0.6 -3.2 4Fe-4S binding protein compare
MMP_RS04500 -0.6 -4.3 adenosylmethionine--8-amino-7-oxononanoate transaminase compare
MMP_RS03220 -0.6 -1.2 RNA 2' 3'-cyclic phosphodiesterase compare
MMP_RS01700 -0.6 -0.4 dihydroxy-acid dehydratase compare
MMP_RS02135 -0.6 -1.5 DUF5612 domain-containing protein compare
MMP_RS01840 -0.6 -2.7 TIGR00289 family protein compare
MMP_RS02940 -0.6 -3.4 TatD family hydrolase compare
MMP_RS02245 -0.6 -1.0 hypothetical protein compare
MMP_RS08570 -0.6 -3.0 coenzyme F420-0:L-glutamate ligase compare
MMP_RS01755 -0.6 -0.6 DUF2097 domain-containing protein compare
MMP_RS06520 -0.6 -1.9 DUF1786 domain-containing protein compare
MMP_RS02580 -0.6 -2.6 cupin domain-containing protein compare
MMP_RS03305 -0.6 -2.7 winged helix-turn-helix domain-containing protein compare
MMP_RS08995 -0.6 -0.8 hypothetical protein compare
MMP_RS02235 -0.6 -3.1 CBS domain-containing protein compare
MMP_RS06980 -0.6 -1.8 tRNA 2-thiocytidine biosynthesis TtcA family protein compare
MMP_RS05540 -0.6 -1.4 hypothetical protein compare
MMP_RS01115 -0.6 -3.5 molybdopterin molybdotransferase MoeA compare
MMP_RS01415 -0.6 -1.7 DUF2067 domain-containing protein compare
MMP_RS08310 -0.6 -0.9 TMEM165/GDT1 family protein compare
MMP_RS01150 -0.6 -3.0 aldo/keto reductase compare
MMP_RS03395 -0.6 -2.0 hypothetical protein compare
MMP_RS06435 -0.6 -1.8 CBS domain-containing protein compare
MMP_RS01640 -0.6 -2.6 2-oxoacid:acceptor oxidoreductase subunit alpha compare
MMP_RS02300 -0.6 -1.9 NAD(P)H-dependent oxidoreductase compare
MMP_RS06705 -0.6 -2.3 formate/nitrite transporter family protein compare
MMP_RS00655 -0.6 -1.4 hypothetical protein compare
MMP_RS06570 -0.6 -1.4 DUF190 domain-containing protein compare
MMP_RS08645 -0.6 -2.3 UPF0179 family protein compare
MMP_RS05950 -0.6 -2.7 nickel-dependent hydrogenase large subunit compare
MMP_RS03120 -0.6 -1.6 hypothetical protein compare
MMP_RS07915 -0.6 -2.0 DUF4870 domain-containing protein compare
MMP_RS01005 -0.5 -0.5 riboflavin synthase compare
MMP_RS02480 -0.5 -0.6 hypothetical protein compare
MMP_RS01490 -0.5 -2.5 tetratricopeptide repeat protein compare
MMP_RS05815 -0.5 -0.8 NOL1/NOP2/sun family putative RNA methylase compare
MMP_RS01095 -0.5 -1.8 iron ABC transporter permease compare
MMP_RS00830 -0.5 -1.0 purine phosphoribosyltransferase family protein compare
MMP_RS05110 -0.5 -2.1 16S ribosomal RNA methyltransferase A compare
MMP_RS07090 -0.5 -2.3 tRNA (adenine-N1)-methyltransferase compare
MMP_RS07970 -0.5 -0.8 hypothetical protein compare
MMP_RS06680 -0.5 -2.7 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS07645 -0.5 -2.4 aldehyde dehydrogenase family protein compare
MMP_RS00635 -0.5 -1.9 energy-coupling factor transporter transmembrane protein EcfT compare
MMP_RS00430 -0.5 -2.1 hypothetical protein compare
MMP_RS05835 -0.5 -0.3 secondary thiamine-phosphate synthase enzyme YjbQ compare
MMP_RS07840 -0.5 -1.2 ribonuclease III compare
MMP_RS05280 -0.5 -2.1 COG1361 S-layer family protein compare
MMP_RS04735 -0.5 -2.3 tautomerase family protein compare
MMP_RS00385 -0.5 -2.5 P-II family nitrogen regulator compare
MMP_RS02310 -0.5 -0.8 RimK-like ATPgrasp N-terminal domain-containing protein compare
MMP_RS01650 -0.5 -0.4 sulfurtransferase TusA family protein compare
MMP_RS06555 -0.5 -1.3 cupin domain-containing protein compare
MMP_RS06710 -0.5 -2.1 selenium-binding protein compare
MMP_RS02230 -0.5 -2.9 sodium-dependent transporter compare
MMP_RS08690 -0.5 -2.3 RNA-guided pseudouridylation complex pseudouridine synthase subunit Cbf5 compare
MMP_RS01990 -0.5 -1.2 hypothetical protein compare
MMP_RS02540 -0.5 -1.7 DUF2283 domain-containing protein compare
MMP_RS06630 -0.5 -0.3 UPF0058 family protein compare
MMP_RS01045 -0.5 -2.0 diphthamide biosynthesis enzyme Dph2 compare
MMP_RS02730 -0.5 -2.7 ModD protein compare
MMP_RS08990 -0.5 -2.5 hypothetical protein compare
MMP_RS03230 -0.5 -1.5 flavodoxin family protein compare
MMP_RS01435 -0.5 -1.6 DMT family transporter compare
MMP_RS01445 -0.5 -1.9 hypothetical protein compare
MMP_RS08785 -0.5 -0.4 RNA-protein complex protein Nop10 compare
MMP_RS00700 -0.5 -1.9 OB-fold nucleic acid binding domain-containing protein compare
MMP_RS07380 -0.5 -0.5 transcription elongation factor Spt5 compare
MMP_RS06915 -0.5 -2.2 metallophosphoesterase compare
MMP_RS07635 -0.4 -1.5 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS06515 -0.4 -0.6 UPF0489 family protein compare
MMP_RS04145 -0.4 -0.6 hypothetical protein compare
MMP_RS07185 -0.4 -2.6 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS08265 -0.4 -1.7 rubrerythrin compare
MMP_RS05770 -0.4 -2.2 YkgJ family cysteine cluster protein compare
MMP_RS01725 -0.4 -0.8 class I SAM-dependent methyltransferase family protein compare
MMP_RS06920 -0.4 -2.5 AAA family ATPase compare
MMP_RS01330 -0.4 -2.6 DHH family phosphoesterase compare
MMP_RS06285 -0.4 -0.6 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS08390 -0.4 -1.7 DUF5400 domain-containing protein compare
MMP_RS06860 -0.4 -0.7 4Fe-4S binding protein compare
MMP_RS08320 -0.4 -1.8 molybdopterin molybdotransferase MoeA compare
MMP_RS00740 -0.4 -1.3 cyclase family protein compare
MMP_RS01870 -0.4 -2.3 acyl-CoA dehydratase activase compare
MMP_RS05480 -0.4 -2.9 NAD(P)/FAD-dependent oxidoreductase compare
MMP_RS05365 -0.4 -0.7 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH compare
MMP_RS08480 -0.4 -3.0 molybdate ABC transporter substrate-binding protein compare
MMP_RS06355 -0.4 -0.7 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS00535 -0.4 -1.1 TIGR00375 family protein compare
MMP_RS05505 -0.4 -1.4 class IV adenylate cyclase compare
MMP_RS07525 -0.4 -1.6 4Fe-4S binding protein compare
MMP_RS02470 -0.4 -0.4 helix-turn-helix transcriptional regulator compare
MMP_RS04185 -0.4 -2.1 aldo/keto reductase compare
MMP_RS02490 -0.4 -1.3 hypothetical protein compare
MMP_RS02320 -0.4 -1.7 glutamate-cysteine ligase family protein compare
MMP_RS02380 -0.4 -2.2 ATP-binding protein compare
MMP_RS06375 -0.4 -1.0 ATP-dependent sacrificial sulfur transferase LarE compare
MMP_RS06585 -0.4 -0.7 DMT family protein compare
MMP_RS06480 -0.4 -1.0 ABC transporter substrate-binding protein compare
MMP_RS06305 -0.4 -2.2 transporter substrate-binding domain-containing protein compare
MMP_RS03420 -0.4 -1.5 acetolactate synthase small subunit compare
MMP_RS06765 -0.4 -1.6 flap endonuclease-1 compare
MMP_RS00810 -0.4 -1.3 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS02690 -0.4 -1.6 FmdE family protein compare
MMP_RS06685 -0.4 -2.2 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS06530 -0.4 -1.7 bifunctional hexulose-6-phosphate synthase/ribonuclease regulator compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in natural competence experiments

For natural competence Neomycin trisulfate salt hydrate across organisms