Experiment set5IT059 for Methanococcus maripaludis S2

Compare to:

H2 McCas- cells grown in liquid medium with neomycin

200 most detrimental genes:

  gene name fitness t score description  
MMP_RS07620 +8.2 3.7 energy-coupling factor ABC transporter substrate-binding protein compare
MMP_RS07555 +7.7 10.1 monovalent cation/H+ antiporter subunit E compare
MMP_RS07615 +7.1 2.8 energy-coupling factor ABC transporter permease compare
MMP_RS03700 +6.3 20.7 sodium:proton antiporter compare
MMP_RS02355 +4.9 3.0 30S ribosomal protein S27ae compare
MMP_RS05925 +4.3 2.8 small nuclear ribonucleoprotein compare
MMP_RS05445 +3.8 4.6 CoB--CoM heterodisulfide reductase subunit B compare
MMP_RS05450 +3.3 2.7 CoB--CoM heterodisulfide reductase subunit C compare
MMP_RS06295 +3.3 9.2 methanogenesis marker 14 protein compare
MMP_RS02800 +3.3 2.4 nucleotidyltransferase domain-containing protein compare
MMP_RS03535 +3.2 3.8 helix-turn-helix transcriptional regulator compare
MMP_RS01795 +2.2 4.7 methanogenesis marker 6 protein compare
MMP_RS03540 +2.1 1.7 DUF2178 domain-containing protein compare
MMP_RS02240 +2.1 5.4 methanogenesis marker 7 protein compare
MMP_RS06400 +1.8 1.9 4Fe-4S binding protein compare
MMP_RS01665 +1.5 5.3 DUF2111 domain-containing protein compare
MMP_RS00985 +1.5 3.0 CDC48 family AAA ATPase compare
MMP_RS04710 +1.5 1.6 hypothetical protein compare
MMP_RS04720 +1.4 3.9 DedA family protein compare
MMP_RS06230 +1.4 2.9 helix-turn-helix domain-containing protein compare
MMP_RS00335 +1.4 2.8 5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH compare
MMP_RS03445 +1.4 1.9 methanogenesis marker 17 protein compare
MMP_RS00310 +1.4 2.4 CBS domain-containing protein compare
MMP_RS06940 +1.4 2.9 polyprenyl diphosphate synthase compare
MMP_RS03205 +1.3 1.2 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS08720 +1.3 1.2 4Fe-4S binding protein compare
MMP_RS07385 +1.2 3.1 protein translocase SEC61 complex subunit gamma compare
MMP_RS05145 +1.1 3.1 hypothetical protein compare
MMP_RS01525 +1.1 1.8 nucleoside-diphosphate kinase compare
MMP_RS06745 +1.1 2.6 DUF2119 domain-containing protein compare
MMP_RS04520 +1.1 0.9 nucleoside deaminase compare
MMP_RS00945 +1.1 1.3 PadR family transcriptional regulator compare
MMP_RS03385 +1.0 1.1 cation diffusion facilitator family transporter compare
MMP_RS09055 +1.0 1.2 CAP domain-containing protein compare
MMP_RS09035 +0.9 2.2 hypothetical protein compare
MMP_RS07005 +0.9 0.4 4Fe-4S binding protein compare
MMP_RS03640 +0.9 1.4 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS03585 +0.9 2.3 Hsp20/alpha crystallin family protein compare
MMP_RS00130 +0.8 0.5 nickel-responsive transcriptional regulator NikR compare
MMP_RS03320 +0.8 2.5 metal-dependent transcriptional regulator compare
MMP_RS01605 +0.8 2.1 hypothetical protein compare
MMP_RS07390 +0.8 1.3 cell division protein FtsZ compare
MMP_RS02340 +0.8 1.0 DNA-directed RNA polymerase subunit E'' compare
MMP_RS03340 +0.8 0.9 ABC transporter ATP-binding protein compare
MMP_RS06475 +0.7 1.6 FAD-dependent oxidoreductase compare
MMP_RS01545 +0.7 0.4 CBS domain-containing protein compare
MMP_RS00305 +0.7 0.7 phosphoribosyl-ATP diphosphatase compare
MMP_RS08650 +0.7 1.2 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS07200 +0.7 2.6 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS06155 +0.7 0.7 DUF4186 domain-containing protein compare
MMP_RS00825 +0.7 1.5 fumarylacetoacetate hydrolase family protein compare
MMP_RS09050 +0.7 1.5 CAP domain-containing protein compare
MMP_RS01940 +0.7 2.4 MoxR family ATPase compare
MMP_RS02225 +0.7 2.5 carbohydrate kinase family protein compare
MMP_RS02475 +0.7 0.5 hypothetical protein compare
MMP_RS02450 +0.6 1.0 hypothetical protein compare
MMP_RS05955 +0.6 1.1 CoB--CoM heterodisulfide reductase subunit C compare
MMP_RS06600 +0.6 0.8 class III signal peptide-containing protein compare
MMP_RS05910 +0.6 2.0 cell division ATPase MinD compare
MMP_RS04890 +0.6 0.4 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS08300 +0.6 0.5 metal-sulfur cluster assembly factor compare
MMP_RS02145 +0.6 1.9 winged helix-turn-helix transcriptional regulator compare
MMP_RS06110 +0.6 1.3 ATP-dependent protease LonB compare
MMP_RS08600 +0.6 1.4 flagellar protein D compare
MMP_RS06430 +0.6 1.6 6-carboxytetrahydropterin synthase QueD compare
MMP_RS00320 +0.6 0.9 class I SAM-dependent methyltransferase compare
MMP_RS06625 +0.6 0.7 DNA primase compare
MMP_RS00250 +0.6 3.7 Flp pilus assembly complex ATPase component TadA compare
MMP_RS05345 +0.6 2.1 hypothetical protein compare
MMP_RS07350 +0.6 1.1 preprotein translocase subunit Sec61beta compare
MMP_RS08605 +0.6 1.9 flagellar protein E compare
MMP_RS07600 +0.5 1.0 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS07875 +0.5 1.9 hypothetical protein compare
MMP_RS00150 +0.5 3.1 AAA family ATPase compare
MMP_RS05640 +0.5 2.1 UTP--glucose-1-phosphate uridylyltransferase GalU compare
MMP_RS03785 +0.5 1.4 cupin domain-containing protein compare
MMP_RS02650 +0.5 1.8 flavodoxin family protein compare
MMP_RS08595 +0.5 0.5 flagellar protein C compare
MMP_RS05675 +0.5 1.0 phosphate ABC transporter ATP-binding protein PstB compare
MMP_RS01305 +0.5 3.1 hypothetical protein compare
MMP_RS00245 +0.5 3.4 type II secretion system F family protein compare
MMP_RS01775 +0.5 1.0 TIGR00297 family protein compare
MMP_RS08395 +0.5 1.2 DsrE family protein compare
MMP_RS07330 +0.5 3.4 membrane protein compare
MMP_RS06130 +0.5 0.9 peptidylprolyl isomerase compare
MMP_RS01600 +0.5 0.6 50S ribosomal protein L15e compare
MMP_RS04740 +0.5 1.4 DUF473 domain-containing protein compare
MMP_RS00050 +0.5 1.7 AarF/UbiB family protein compare
MMP_RS05660 +0.5 1.7 phosphate ABC transporter substrate-binding protein compare
MMP_RS03245 +0.5 1.2 DNA repair and recombination protein RadB compare
MMP_RS07335 +0.5 1.5 tRNA (cytidine(56)-2'-O)-methyltransferase compare
MMP_RS07140 +0.5 2.8 TIGR00341 family protein compare
MMP_RS01895 +0.4 2.8 flippase compare
MMP_RS02675 +0.4 1.1 hypothetical protein compare
MMP_RS07860 +0.4 0.2 hypothetical protein compare
MMP_RS08670 +0.4 1.2 metallophosphoesterase compare
MMP_RS01110 +0.4 0.8 FmdE family protein compare
MMP_RS08245 +0.4 1.9 DUF4013 domain-containing protein compare
MMP_RS08705 +0.4 1.5 sulfopyruvate decarboxylase subunit beta compare
MMP_RS06035 +0.4 2.1 glycosyltransferase family 2 protein compare
MMP_RS08890 +0.4 3.2 glycosyltransferase family 4 protein compare
MMP_RS08855 +0.4 1.3 hypothetical protein compare
MMP_RS08745 +0.4 1.2 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS01540 +0.4 1.1 DUF504 domain-containing protein compare
MMP_RS00520 +0.4 0.5 RNA polymerase Rpb4 family protein compare
MMP_RS01570 +0.4 0.6 hypothetical protein compare
MMP_RS05295 +0.4 2.3 minichromosome maintenance protein MCM compare
MMP_RS00240 +0.4 2.8 type II secretion system F family protein compare
MMP_RS05875 +0.4 0.7 hydroxyethylthiazole kinase compare
MMP_RS07195 +0.4 1.4 M20 family metallo-hydrolase compare
MMP_RS01945 +0.4 2.0 DUF4350 domain-containing protein compare
MMP_RS03775 +0.4 1.2 4Fe-4S dicluster domain-containing protein compare
MMP_RS08460 +0.4 0.8 proteasome-activating nucleotidase compare
MMP_RS05580 +0.4 2.7 glycosyltransferase compare
MMP_RS07765 +0.4 3.0 sodium:alanine symporter family protein compare
MMP_RS03800 +0.4 1.4 hypothetical protein compare
MMP_RS04630 +0.4 1.3 3'-5' exonuclease compare
MMP_RS01890 +0.4 0.9 nucleotide sugar dehydrogenase compare
MMP_RS08160 +0.4 1.8 EamA family transporter compare
MMP_RS05820 +0.4 1.8 RNA-binding transcriptional accessory protein compare
MMP_RS00515 +0.4 0.4 DUF655 domain-containing protein compare
MMP_RS06535 +0.4 1.3 2-oxoacid:acceptor oxidoreductase family protein compare
MMP_RS01250 +0.4 1.0 tRNA (guanine(26)-N(2))-dimethyltransferase compare
MMP_RS04325 +0.4 1.7 MtaA/CmuA family methyltransferase compare
MMP_RS02190 +0.4 0.9 sulfopyruvate decarboxylase subunit alpha compare
MMP_RS00565 +0.4 0.9 CBS domain-containing protein compare
MMP_RS07190 +0.4 1.5 chromosome segregation protein SMC compare
MMP_RS05150 +0.4 1.7 hypothetical protein compare
MMP_RS07835 +0.4 1.0 TldD/PmbA family protein compare
MMP_RS04015 +0.4 1.0 hypothetical protein compare
MMP_RS02455 +0.4 1.4 hypothetical protein compare
MMP_RS00280 +0.4 1.8 DUF2118 domain-containing protein compare
MMP_RS00695 +0.4 0.2 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS00690 +0.4 1.3 MBL fold metallo-hydrolase compare
MMP_RS00990 +0.4 1.9 hypothetical protein compare
MMP_RS01950 +0.4 2.0 hypothetical protein compare
MMP_RS00105 +0.4 1.6 hypothetical protein compare
MMP_RS01800 +0.4 0.7 TIGR00303 family protein compare
MMP_RS02790 +0.4 0.4 class III signal peptide-containing protein compare
MMP_RS02085 +0.3 1.3 inosine/xanthosine triphosphatase compare
MMP_RS00395 +0.3 0.7 MGMT family protein compare
MMP_RS05510 +0.3 1.2 Rrf2 family transcriptional regulator compare
MMP_RS00625 +0.3 1.2 hypothetical protein compare
MMP_RS01420 +0.3 0.7 hypothetical protein compare
MMP_RS08635 +0.3 0.3 UbiA family prenyltransferase compare
MMP_RS05895 +0.3 2.0 metallophosphoesterase compare
MMP_RS09045 +0.3 2.1 class III signal peptide-containing protein compare
MMP_RS01310 +0.3 1.8 hypothetical protein compare
MMP_RS02610 +0.3 1.0 DUF2162 domain-containing protein compare
MMP_RS07910 +0.3 1.6 NAD(P)H-hydrate dehydratase compare
MMP_RS03715 +0.3 1.3 class III signal peptide-containing protein compare
MMP_RS03580 +0.3 0.6 signal recognition particle-docking protein FtsY compare
MMP_RS03755 +0.3 1.6 MarR family transcriptional regulator compare
MMP_RS00315 +0.3 1.7 Nif3-like dinuclear metal center hexameric protein compare
MMP_RS04900 +0.3 2.5 hypothetical protein compare
MMP_RS08630 +0.3 1.3 archaellar assembly protein FlaJ compare
MMP_RS03670 +0.3 1.5 DUF1890 domain-containing protein compare
MMP_RS03465 +0.3 0.4 adenine phosphoribosyltransferase compare
MMP_RS08770 +0.3 1.8 hypothetical protein compare
MMP_RS03090 +0.3 1.1 cation:proton antiporter compare
MMP_RS06735 +0.3 1.2 class I SAM-dependent rRNA methyltransferase compare
MMP_RS02290 +0.3 1.6 MBL fold metallo-hydrolase compare
MMP_RS04690 +0.3 1.0 class III signal peptide-containing protein compare
MMP_RS08930 +0.3 0.6 hypothetical protein compare
MMP_RS07125 +0.3 1.1 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS04650 +0.3 1.5 tetratricopeptide repeat protein compare
MMP_RS08175 +0.3 1.2 7-cyano-7-deazaguanine synthase compare
MMP_RS01880 +0.3 1.0 DegT/DnrJ/EryC1/StrS family aminotransferase compare
MMP_RS01955 +0.3 0.6 hypothetical protein compare
MMP_RS07420 +0.3 1.1 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS07790 +0.3 1.2 segregation/condensation protein A compare
MMP_RS06760 +0.3 0.8 hypothetical protein compare
MMP_RS00800 +0.3 1.1 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS08130 +0.3 1.6 IGHMBP2 family helicase compare
MMP_RS06590 +0.3 0.7 GNAT family N-acetyltransferase compare
MMP_RS08615 +0.3 0.3 flagellar protein G compare
MMP_RS00195 +0.3 2.4 DUF4013 domain-containing protein compare
MMP_RS00895 +0.3 0.8 hypothetical protein compare
MMP_RS09025 +0.3 0.4 hypothetical protein compare
MMP_RS07130 +0.3 1.1 coenzyme F420 hydrogenase subunit gamma compare
MMP_RS08980 +0.3 1.2 hypothetical protein compare
MMP_RS07800 +0.3 1.3 ATP-binding cassette domain-containing protein compare
MMP_RS08750 +0.3 0.7 hypothetical protein compare
MMP_RS00235 +0.3 1.3 HDIG domain-containing protein compare
MMP_RS01470 +0.3 0.7 ATP-binding cassette domain-containing protein compare
MMP_RS06275 +0.3 1.2 ATP-dependent DNA helicase compare
MMP_RS03215 +0.3 1.3 MBL fold metallo-hydrolase compare
MMP_RS04205 +0.3 0.6 carboxymuconolactone decarboxylase family protein compare
MMP_RS00300 +0.3 0.2 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS02840 +0.3 1.1 DUF123 domain-containing protein compare
MMP_RS03685 +0.3 1.1 Mrp/NBP35 family ATP-binding protein compare
MMP_RS02110 +0.3 0.6 hypothetical protein compare
MMP_RS00085 +0.3 1.2 DNA cytosine methyltransferase compare
MMP_RS05275 +0.3 1.3 AI-2E family transporter compare
MMP_RS00965 +0.3 0.6 hypothetical protein compare
MMP_RS03480 +0.3 1.0 SulP family inorganic anion transporter compare
MMP_RS05795 +0.2 0.4 redox-regulated ATPase YchF compare
MMP_RS01430 +0.2 1.4 mechanosensitive ion channel family protein compare
MMP_RS04955 +0.2 1.1 DNA topoisomerase I compare
MMP_RS00445 +0.2 1.4 7-carboxy-7-deazaguanine synthase QueE compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in natural competence experiments

For natural competence Neomycin trisulfate salt hydrate across organisms