Experiment set5IT059 for Klebsiella michiganensis M5al

Compare to:

D-Serine carbon source

200 most important genes:

  gene name fitness t score description  
BWI76_RS20355 -8.1 -5.6 colicin V production protein compare
BWI76_RS00990 -7.7 -5.3 ketol-acid reductoisomerase compare
BWI76_RS18950 -7.6 -5.3 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS04675 -6.9 -6.7 3-isopropylmalate dehydrogenase compare
BWI76_RS09760 -6.8 -6.6 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS23220 -6.7 -6.5 amino-acid N-acetyltransferase compare
BWI76_RS18920 -6.7 -4.6 ATP phosphoribosyltransferase compare
BWI76_RS00850 -6.7 -7.9 acetylglutamate kinase compare
BWI76_RS00855 -6.4 -7.6 argininosuccinate lyase compare
BWI76_RS01655 -6.3 -8.5 homoserine O-succinyltransferase compare
BWI76_RS05840 -6.3 -6.1 glutamate 5-kinase compare
BWI76_RS05835 -6.2 -4.3 gamma-glutamyl-phosphate reductase compare
BWI76_RS11855 -6.1 -7.4 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS04465 -5.9 -5.7 carbamoyl-phosphate synthase small subunit compare
BWI76_RS08385 -5.9 -3.4 citrate (Si)-synthase compare
BWI76_RS23360 -5.8 -4.0 diaminopimelate decarboxylase compare
BWI76_RS26085 -5.5 -3.8 3-dehydroquinate synthase compare
BWI76_RS01615 -5.5 -11.1 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS17720 -5.4 -2.3 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS04250 -5.3 -6.9 homoserine kinase compare
BWI76_RS04470 -5.3 -11.2 carbamoyl phosphate synthase large subunit compare
BWI76_RS21465 -5.3 -5.6 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS18940 -5.2 -6.5 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS04255 -5.2 -8.2 threonine synthase compare
BWI76_RS04670 -5.2 -11.1 3-isopropylmalate dehydratase large subunit compare
BWI76_RS18925 -5.1 -6.5 histidinol dehydrogenase compare
BWI76_RS04245 -5.0 -15.2 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS09645 -5.0 -2.1 thioredoxin-disulfide reductase compare
BWI76_RS04665 -5.0 -15.6 3-isopropylmalate dehydratase small subunit compare
BWI76_RS18935 -5.0 -8.7 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS11860 -4.8 -10.3 anthranilate synthase component I compare
BWI76_RS11850 -4.8 -10.8 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS04680 -4.8 -12.4 2-isopropylmalate synthase compare
BWI76_RS09755 -4.8 -7.7 phosphoserine transaminase compare
BWI76_RS07065 -4.8 -9.3 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS26460 -4.8 -5.2 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS00845 -4.8 -8.4 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS00965 -4.8 -2.0 acetolactate synthase 2 small subunit compare
BWI76_RS02815 -4.7 -3.4 fructose-bisphosphatase class I compare
BWI76_RS25115 -4.7 -7.1 argininosuccinate synthase compare
BWI76_RS18955 -4.5 -5.8 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS21475 -4.4 -6.1 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS23920 -4.4 -4.7 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS00975 -4.4 -5.7 dihydroxy-acid dehydratase compare
BWI76_RS21265 -4.3 -13.1 phosphoribosylformylglycinamidine synthase compare
BWI76_RS00980 -4.3 -10.9 PLP-dependent threonine dehydratase compare
BWI76_RS18930 -4.2 -4.6 histidinol-phosphate transaminase compare
BWI76_RS11965 -4.2 -4.1 orotidine-5'-phosphate decarboxylase compare
BWI76_RS09910 -4.2 -18.0 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS03010 -4.2 -5.2 ornithine carbamoyltransferase compare
BWI76_RS00785 -4.2 -7.4 cystathionine gamma-synthase compare
BWI76_RS11845 -4.2 -2.7 tryptophan synthase subunit beta compare
BWI76_RS01610 -4.2 -6.7 phosphoribosylamine--glycine ligase compare
BWI76_RS26455 -4.1 -3.8 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
BWI76_RS05015 -4.1 -4.4 transcriptional regulator compare
BWI76_RS04685 -4.1 -6.7 putative leucine operon leader peptide compare
BWI76_RS17065 -4.1 -10.8 phosphoenolpyruvate synthase compare
BWI76_RS11840 -4.0 -6.6 tryptophan synthase subunit alpha compare
BWI76_RS22755 -4.0 -10.3 phosphoadenosine phosphosulfate reductase compare
BWI76_RS22765 -4.0 -13.4 sulfite reductase subunit alpha compare
BWI76_RS07070 -3.9 -5.6 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS00985 -3.9 -8.3 transcriptional regulator IlvY compare
BWI76_RS00805 -3.9 -4.5 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS00835 -3.9 -11.8 phosphoenolpyruvate carboxylase compare
BWI76_RS10990 -3.8 -2.5 dihydroorotase compare
BWI76_RS20350 -3.8 -6.7 amidophosphoribosyltransferase compare
BWI76_RS05120 -3.7 -7.7 bifunctional glycosyl transferase/transpeptidase compare
BWI76_RS20435 -3.7 -2.2 chorismate synthase compare
BWI76_RS27860 -3.6 -10.1 D-serine dehydratase conserved
BWI76_RS20895 -3.6 -6.3 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS04160 -3.6 -7.2 phosphoserine phosphatase compare
BWI76_RS22690 -3.5 -4.6 adenylyl-sulfate kinase compare
BWI76_RS04645 -3.5 -3.1 3-dehydroquinase compare
BWI76_RS00400 -3.5 -2.3 glutamine synthetase compare
BWI76_RS24285 -3.4 -6.5 cystathionine beta-lyase compare
BWI76_RS20965 -3.4 -3.3 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS02735 -3.4 -5.6 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS22760 -3.3 -7.0 sulfite reductase subunit beta compare
BWI76_RS04705 -3.3 -8.2 DNA-binding transcriptional regulator FruR compare
BWI76_RS27385 -3.3 -6.1 orotate phosphoribosyltransferase compare
BWI76_RS23365 -3.3 -6.5 LysR family transcriptional regulator compare
BWI76_RS15350 -3.0 -2.2 hypothetical protein compare
BWI76_RS27390 -3.0 -5.2 ribonuclease PH compare
BWI76_RS22805 -2.9 -7.3 GTP diphosphokinase compare
BWI76_RS15825 -2.9 -2.6 hypothetical protein compare
BWI76_RS02995 -2.8 -5.2 aspartate carbamoyltransferase compare
BWI76_RS00960 -2.7 -6.1 acetolactate synthase 2 catalytic subunit compare
BWI76_RS04240 -2.7 -3.8 thr operon leader peptide compare
BWI76_RS26000 -2.7 -6.3 aspartate aminotransferase family protein compare
BWI76_RS23230 -2.6 -3.9 exodeoxyribonuclease V subunit beta compare
BWI76_RS26570 -2.4 -3.7 anion permease compare
BWI76_RS09660 -2.4 -2.5 DNA translocase FtsK compare
BWI76_RS16275 -2.4 -3.3 fumarate hydratase FumA compare
BWI76_RS00345 -2.4 -3.9 protein disulfide oxidoreductase DsbA compare
BWI76_RS08430 -2.3 -5.1 succinate--CoA ligase subunit alpha compare
BWI76_RS19840 -2.3 -1.9 hypothetical protein compare
BWI76_RS25645 -2.3 -7.5 shikimate dehydrogenase compare
BWI76_RS01200 -2.3 -2.7 diaminopimelate epimerase compare
BWI76_RS01210 -2.3 -3.2 tyrosine recombinase XerC compare
BWI76_RS23240 -2.3 -3.9 exonuclease V subunit gamma compare
BWI76_RS12090 -2.1 -3.9 HNH endonuclease compare
BWI76_RS19495 -2.1 -1.9 ABC transporter, quaternary amine uptake transporter (QAT) family, ATP-binding protein compare
BWI76_RS08425 -2.1 -5.2 succinyl-CoA ligase subunit beta compare
BWI76_RS20970 -2.1 -2.1 phosphoribosylglycinamide formyltransferase compare
BWI76_RS08405 -2.0 -2.8 succinate dehydrogenase flavoprotein subunit compare
BWI76_RS27850 -2.0 -4.8 DNA-binding transcriptional regulator DsdC compare
BWI76_RS26055 -2.0 -8.5 siroheme synthase compare
BWI76_RS05200 -2.0 -3.2 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS08390 -1.9 -4.3 hypothetical protein compare
BWI76_RS25070 -1.8 -1.7 hypothetical protein compare
BWI76_RS00180 -1.8 -2.4 F0F1 ATP synthase subunit epsilon compare
BWI76_RS20155 -1.7 -1.9 NADH-quinone oxidoreductase subunit I compare
BWI76_RS27440 -1.6 -3.8 DNA helicase RecG compare
BWI76_RS01185 -1.6 -2.5 adenylate cyclase compare
BWI76_RS08395 -1.6 -2.4 succinate dehydrogenase cytochrome b556 large subunit compare
BWI76_RS00140 -1.6 -1.4 phosphate transport system regulator PhoU compare
BWI76_RS21480 -1.5 -4.7 phospho-2-dehydro-3-deoxyheptonate aldolase compare
BWI76_RS04515 -1.5 -1.8 Co2+/Mg2+ efflux protein ApaG compare
BWI76_RS01800 -1.5 -3.2 glucose-6-phosphate isomerase compare
BWI76_RS19330 -1.5 -1.5 HAD family hydrolase compare
BWI76_RS20440 -1.5 -1.8 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS15835 -1.5 -1.0 hypothetical protein compare
BWI76_RS16315 -1.5 -2.1 SirA-like protein compare
BWI76_RS04510 -1.4 -1.8 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) compare
BWI76_RS18605 -1.4 -2.5 oxidoreductase molybdopterin-binding protein compare
BWI76_RS12465 -1.4 -1.2 phage shock protein D compare
BWI76_RS23480 -1.4 -7.2 EAL domain-containing protein compare
BWI76_RS07780 -1.4 -1.7 hypothetical protein compare
BWI76_RS23885 -1.4 -2.0 2-octaprenylphenol hydroxylase compare
BWI76_RS15215 -1.4 -1.1 N-acetyltransferase compare
BWI76_RS22695 -1.4 -3.3 sulfate adenylyltransferase compare
BWI76_RS20640 -1.4 -3.6 cysteine synthase A compare
BWI76_RS25600 -1.4 -1.2 tRNA-Thr compare
BWI76_RS05260 -1.3 -1.7 chaperone compare
BWI76_RS26075 -1.3 -2.4 DNA adenine methylase compare
BWI76_RS11155 -1.2 -2.6 penicillin-binding protein activator LpoB compare
BWI76_RS01110 -1.2 -2.5 TDP-fucosamine acetyltransferase compare
BWI76_RS01350 -1.2 -1.0 NAD(P)H-flavin reductase compare
BWI76_RS06495 -1.2 -6.1 cytochrome ubiquinol oxidase subunit II compare
BWI76_RS02985 -1.2 -2.7 reactive intermediate/imine deaminase compare
BWI76_RS00390 -1.2 -3.2 two-component system sensor histidine kinase NtrB compare
BWI76_RS04875 -1.2 -2.4 transcriptional regulator PdhR compare
BWI76_RS26620 -1.2 -1.2 Fe-S biogenesis protein NfuA compare
BWI76_RS20650 -1.2 -2.2 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS08210 -1.2 -1.8 N-acetylglucosamine-6-phosphate deacetylase compare
BWI76_RS17945 -1.2 -1.7 hypothetical protein compare
BWI76_RS08520 -1.1 -2.6 colicin transporter TolQ compare
BWI76_RS19035 -1.1 -5.6 dTDP-rhamnosyl transferase compare
BWI76_RS15810 -1.1 -3.5 hypothetical protein compare
BWI76_RS06525 -1.1 -4.6 ATP-dependent Clp protease proteolytic subunit compare
BWI76_RS23830 -1.1 -5.8 hypothetical protein compare
BWI76_RS10575 -1.1 -1.4 polar amino acid ABC transporter permease compare
BWI76_RS16660 -1.1 -1.9 SfnB family sulfur acquisition oxidoreductase compare
BWI76_RS04530 -1.1 -1.8 peptidylprolyl isomerase SurA compare
BWI76_RS20785 -1.1 -1.2 ethanolamine utilization protein EutJ compare
BWI76_RS21165 -1.1 -1.8 Fe-S cluster assembly transcriptional regulator IscR compare
BWI76_RS21945 -1.1 -2.5 LysR family transcriptional regulator compare
BWI76_RS16515 -1.1 -2.2 LysR family transcriptional regulator compare
BWI76_RS15840 -1.1 -2.9 prophage protein compare
BWI76_RS09970 -1.1 -1.7 porin OmpA compare
BWI76_RS17370 -1.1 -2.1 nitrate transporter NasD compare
BWI76_RS11040 -1.0 -2.5 ribonuclease E compare
BWI76_RS27175 -1.0 -4.1 hypothetical protein compare
BWI76_RS02580 -1.0 -1.6 23S rRNA (guanosine(2251)-2'-O)-methyltransferase compare
BWI76_RS20170 -1.0 -3.3 NADH-quinone oxidoreductase subunit F compare
BWI76_RS02410 -1.0 -1.3 EF-P beta-lysylation protein EpmB compare
BWI76_RS06730 -1.0 -1.5 lac repressor compare
BWI76_RS17615 -1.0 -1.7 RNA pseudouridine synthase compare
BWI76_RS20995 -1.0 -4.0 RNA degradosome polyphosphate kinase compare
BWI76_RS26095 -1.0 -1.2 shikimate kinase compare
BWI76_RS06505 -1.0 -3.4 hypothetical protein compare
BWI76_RS15830 -1.0 -1.9 hypothetical protein compare
BWI76_RS06485 -0.9 -1.7 cytochrome o ubiquinol oxidase subunit III compare
BWI76_RS21140 -0.9 -1.6 molecular chaperone HscA compare
BWI76_RS10745 -0.9 -1.0 hypothetical protein compare
BWI76_RS19240 -0.9 -1.4 ABC transporter substrate-binding protein compare
BWI76_RS01935 -0.9 -1.9 thiamin phosphate synthase compare
BWI76_RS11900 -0.9 -1.0 cob(I)yrinic acid a,c-diamide adenosyltransferase compare
BWI76_RS17675 -0.9 -2.0 hypothetical protein compare
BWI76_RS25425 -0.9 -1.4 arginine repressor compare
BWI76_RS18165 -0.9 -1.4 NUDIX pyrophosphatase compare
BWI76_RS00385 -0.9 -5.1 nitrogen assimilation regulatory protein compare
BWI76_RS24945 -0.9 -0.9 glutamine amidotransferase compare
BWI76_RS08535 -0.9 -1.1 translocation protein TolB compare
BWI76_RS21940 -0.9 -2.0 SDR family oxidoreductase compare
BWI76_RS10955 -0.9 -1.4 hypothetical protein compare
BWI76_RS15715 -0.9 -2.2 putative ninG protein compare
BWI76_RS06295 -0.9 -2.8 S-adenosylmethionine:tRNA ribosyltransferase-isomerase compare
BWI76_RS25280 -0.9 -1.5 RNase adaptor protein RapZ compare
BWI76_RS08980 -0.9 -1.0 DNA starvation/stationary phase protection protein compare
BWI76_RS13490 -0.9 -1.3 pyrimidine-specific ribonucleoside hydrolase RihA compare
BWI76_RS07765 -0.9 -1.2 thioesterase compare
BWI76_RS16805 -0.8 -1.5 basic amino acid ABC transporter substrate-binding protein compare
BWI76_RS06535 -0.8 -3.6 endopeptidase La compare
BWI76_RS07740 -0.8 -1.3 Fe2+-enterobactin ABC transporter substrate-binding protein compare
BWI76_RS07465 -0.8 -2.0 TetR family transcriptional regulator compare
BWI76_RS13965 -0.8 -2.2 binding-protein-dependent transport system inner membrane protein compare
BWI76_RS01275 -0.8 -3.5 LysR family transcriptional regulator compare
BWI76_RS15630 -0.8 -2.7 hypothetical protein compare
BWI76_RS16425 -0.8 -1.4 hypothetical protein compare


Specific Phenotypes

For 2 genes in this experiment

For carbon source D-Serine in Klebsiella michiganensis M5al

For carbon source D-Serine across organisms