Experiment set5IT058 for Klebsiella michiganensis M5al

Compare to:

L-Alanine carbon source

200 most important genes:

  gene name fitness t score description  
BWI76_RS18935 -8.3 -5.7 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS04675 -7.6 -5.3 3-isopropylmalate dehydrogenase compare
BWI76_RS18925 -7.4 -5.1 histidinol dehydrogenase compare
BWI76_RS18930 -7.4 -6.6 histidinol-phosphate transaminase compare
BWI76_RS18940 -7.4 -5.1 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS21475 -7.0 -6.9 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS04250 -6.8 -6.6 homoserine kinase compare
BWI76_RS17065 -6.5 -9.9 phosphoenolpyruvate synthase compare
BWI76_RS04670 -6.4 -9.8 3-isopropylmalate dehydratase large subunit compare
BWI76_RS09755 -6.3 -7.5 phosphoserine transaminase compare
BWI76_RS04470 -6.3 -9.6 carbamoyl phosphate synthase large subunit compare
BWI76_RS05835 -6.2 -4.3 gamma-glutamyl-phosphate reductase compare
BWI76_RS18950 -6.2 -4.3 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS07070 -6.2 -4.3 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS00855 -6.0 -8.3 argininosuccinate lyase compare
BWI76_RS04245 -5.9 -13.8 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS04255 -5.9 -9.0 threonine synthase compare
BWI76_RS23920 -5.8 -5.7 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS23360 -5.8 -4.0 diaminopimelate decarboxylase compare
BWI76_RS23220 -5.6 -7.7 amino-acid N-acetyltransferase compare
BWI76_RS26085 -5.5 -3.8 3-dehydroquinate synthase compare
BWI76_RS04665 -5.5 -19.7 3-isopropylmalate dehydratase small subunit compare
BWI76_RS18920 -5.5 -5.3 ATP phosphoribosyltransferase compare
BWI76_RS01210 -5.4 -4.5 tyrosine recombinase XerC compare
BWI76_RS20895 -5.4 -6.4 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS00980 -5.4 -10.9 PLP-dependent threonine dehydratase compare
BWI76_RS04160 -5.3 -6.9 phosphoserine phosphatase compare
BWI76_RS04645 -5.3 -6.2 3-dehydroquinase compare
BWI76_RS09760 -5.3 -8.1 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS00850 -5.3 -6.4 acetylglutamate kinase compare
BWI76_RS20965 -5.1 -6.4 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS01655 -5.1 -6.8 homoserine O-succinyltransferase compare
BWI76_RS01615 -5.0 -11.1 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS09645 -4.9 -2.1 thioredoxin-disulfide reductase compare
BWI76_RS03010 -4.9 -7.2 ornithine carbamoyltransferase compare
BWI76_RS02995 -4.9 -8.4 aspartate carbamoyltransferase compare
BWI76_RS11860 -4.9 -9.3 anthranilate synthase component I compare
BWI76_RS20355 -4.9 -4.2 colicin V production protein compare
BWI76_RS18955 -4.8 -4.5 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS21265 -4.8 -13.4 phosphoribosylformylglycinamidine synthase compare
BWI76_RS05840 -4.8 -5.8 glutamate 5-kinase compare
BWI76_RS00990 -4.7 -10.4 ketol-acid reductoisomerase compare
BWI76_RS00140 -4.6 -2.0 phosphate transport system regulator PhoU compare
BWI76_RS08385 -4.6 -5.4 citrate (Si)-synthase compare
BWI76_RS11840 -4.5 -5.0 tryptophan synthase subunit alpha compare
BWI76_RS25115 -4.5 -6.9 argininosuccinate synthase compare
BWI76_RS09910 -4.4 -17.4 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS04685 -4.3 -8.6 putative leucine operon leader peptide compare
BWI76_RS00975 -4.3 -8.4 dihydroxy-acid dehydratase compare
BWI76_RS04240 -4.3 -2.0 thr operon leader peptide compare
BWI76_RS04705 -4.2 -8.1 DNA-binding transcriptional regulator FruR compare
BWI76_RS00845 -4.2 -6.5 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS05200 -4.2 -2.9 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS10990 -4.2 -4.9 dihydroorotase compare
BWI76_RS02815 -4.1 -2.6 fructose-bisphosphatase class I compare
BWI76_RS27385 -4.1 -7.2 orotate phosphoribosyltransferase compare
BWI76_RS01610 -4.0 -6.4 phosphoribosylamine--glycine ligase compare
BWI76_RS00835 -4.0 -11.6 phosphoenolpyruvate carboxylase compare
BWI76_RS17735 -4.0 -3.4 D-amino acid dehydrogenase small subunit conserved
BWI76_RS11845 -4.0 -2.6 tryptophan synthase subunit beta compare
BWI76_RS15825 -3.9 -3.9 hypothetical protein compare
BWI76_RS11965 -3.9 -4.3 orotidine-5'-phosphate decarboxylase compare
BWI76_RS04680 -3.9 -10.3 2-isopropylmalate synthase compare
BWI76_RS09660 -3.8 -2.6 DNA translocase FtsK compare
BWI76_RS20435 -3.7 -2.3 chorismate synthase compare
BWI76_RS27390 -3.7 -4.8 ribonuclease PH compare
BWI76_RS04465 -3.7 -4.8 carbamoyl-phosphate synthase small subunit compare
BWI76_RS21465 -3.7 -3.7 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS11855 -3.6 -5.9 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS11850 -3.5 -6.9 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS00400 -3.5 -2.3 glutamine synthetase compare
BWI76_RS05015 -3.4 -2.8 transcriptional regulator compare
BWI76_RS23365 -3.4 -8.9 LysR family transcriptional regulator compare
BWI76_RS07065 -3.3 -8.3 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS09640 -3.3 -6.5 cysteine/glutathione ABC transporter permease/ATP-binding protein CydD compare
BWI76_RS23240 -3.2 -4.3 exonuclease V subunit gamma compare
BWI76_RS20350 -3.1 -7.2 amidophosphoribosyltransferase compare
BWI76_RS00805 -3.1 -5.8 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS23230 -3.1 -3.0 exodeoxyribonuclease V subunit beta compare
BWI76_RS08395 -3.1 -2.9 succinate dehydrogenase cytochrome b556 large subunit compare
BWI76_RS00785 -3.1 -5.8 cystathionine gamma-synthase compare
BWI76_RS02530 -3.1 -3.2 tRNA dimethylallyltransferase compare
BWI76_RS02410 -3.0 -2.1 EF-P beta-lysylation protein EpmB compare
BWI76_RS22755 -2.9 -7.1 phosphoadenosine phosphosulfate reductase compare
BWI76_RS06525 -2.9 -5.7 ATP-dependent Clp protease proteolytic subunit compare
BWI76_RS25070 -2.9 -2.1 hypothetical protein compare
BWI76_RS26075 -2.7 -5.6 DNA adenine methylase compare
BWI76_RS20270 -2.6 -7.6 hypothetical protein compare
BWI76_RS00965 -2.6 -1.9 acetolactate synthase 2 small subunit compare
BWI76_RS24900 -2.6 -2.9 DeoR family transcriptional regulator compare
BWI76_RS24285 -2.5 -7.5 cystathionine beta-lyase compare
BWI76_RS09635 -2.5 -3.4 amino acid ABC transporter ATP-binding protein compare
BWI76_RS22765 -2.5 -10.7 sulfite reductase subunit alpha compare
BWI76_RS26175 -2.4 -4.5 DeoR/GlpR family transcriptional regulator compare
BWI76_RS25425 -2.4 -2.5 arginine repressor compare
BWI76_RS20650 -2.3 -2.2 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS22760 -2.3 -5.6 sulfite reductase subunit beta compare
BWI76_RS01185 -2.3 -2.7 adenylate cyclase compare
BWI76_RS02735 -2.3 -4.4 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS04530 -2.3 -2.3 peptidylprolyl isomerase SurA compare
BWI76_RS17720 -2.2 -2.1 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS08525 -2.2 -4.6 colicin transporter compare
BWI76_RS02985 -2.2 -4.9 reactive intermediate/imine deaminase compare
BWI76_RS08405 -2.1 -2.8 succinate dehydrogenase flavoprotein subunit compare
BWI76_RS21100 -2.1 -3.7 nucleoside-diphosphate kinase compare
BWI76_RS20995 -2.1 -4.5 RNA degradosome polyphosphate kinase compare
BWI76_RS05260 -2.0 -2.2 chaperone compare
BWI76_RS23885 -1.9 -2.4 2-octaprenylphenol hydroxylase compare
BWI76_RS14075 -1.9 -1.9 TetR family transcriptional regulator compare
BWI76_RS03415 -1.8 -6.3 LacI family transcriptional regulator compare
BWI76_RS27475 -1.8 -9.9 regulatory protein GntR family protein compare
BWI76_RS05790 -1.7 -2.0 phage DNA-binding protein compare
BWI76_RS20440 -1.7 -3.1 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS19460 -1.7 -2.8 lipoprotein compare
BWI76_RS15850 -1.6 -1.5 DUF1317 domain-containing protein compare
BWI76_RS26460 -1.6 -5.2 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS14050 -1.6 -2.7 AP endonuclease, family 2 compare
BWI76_RS11610 -1.6 -2.5 glutamate dehydrogenase compare
BWI76_RS07820 -1.6 -2.0 S-methyl-5-thioribose kinase compare
BWI76_RS25420 -1.6 -5.4 malate dehydrogenase compare
BWI76_RS23020 -1.6 -3.0 cobalamin biosynthesis protein CbiQ compare
BWI76_RS06530 -1.6 -3.7 ATP-dependent Clp protease ATP-binding subunit ClpX compare
BWI76_RS20720 -1.5 -1.4 hypothetical protein compare
BWI76_RS23265 -1.5 -3.9 hypothetical protein compare
BWI76_RS12450 -1.5 -2.6 phage shock protein PspA compare
BWI76_RS22420 -1.5 -1.6 LacI family transcriptional regulator compare
BWI76_RS15835 -1.5 -1.0 hypothetical protein compare
BWI76_RS23480 -1.5 -8.5 EAL domain-containing protein compare
BWI76_RS16315 -1.5 -1.9 SirA-like protein compare
BWI76_RS16805 -1.4 -2.1 basic amino acid ABC transporter substrate-binding protein compare
BWI76_RS22805 -1.4 -7.2 GTP diphosphokinase compare
BWI76_RS08210 -1.4 -1.6 N-acetylglucosamine-6-phosphate deacetylase compare
BWI76_RS09190 -1.4 -3.2 hypothetical protein compare
BWI76_RS02970 -1.4 -5.7 trehalose operon repressor compare
BWI76_RS06185 -1.4 -6.9 shikimate kinase II compare
BWI76_RS08520 -1.4 -3.3 colicin transporter TolQ compare
BWI76_RS03080 -1.4 -3.5 (Fe-S)-cluster assembly protein compare
BWI76_RS19010 -1.3 -3.3 polysaccharide pyruvyl transferase yvff compare
BWI76_RS00345 -1.3 -2.3 protein disulfide oxidoreductase DsbA compare
BWI76_RS00430 -1.3 -3.3 GNAT family N-acetyltransferase compare
BWI76_RS16760 -1.3 -3.9 lipase compare
BWI76_RS06730 -1.3 -2.1 lac repressor compare
BWI76_RS08730 -1.3 -2.3 histidine utilization repressor compare
BWI76_RS10530 -1.3 -2.1 GntR family transcriptional regulator with compare
BWI76_RS06810 -1.3 -2.2 hypothetical protein compare
BWI76_RS15920 -1.3 -1.5 hypothetical protein compare
BWI76_RS19330 -1.2 -1.3 HAD family hydrolase compare
BWI76_RS27915 -1.2 -2.0 YceK/YidQ family lipoprotein compare
BWI76_RS22625 -1.2 -1.9 transcriptional regulator compare
BWI76_RS20150 -1.2 -1.7 NADH:ubiquinone oxidoreductase subunit J compare
BWI76_RS24945 -1.2 -1.1 glutamine amidotransferase compare
BWI76_RS00985 -1.2 -4.3 transcriptional regulator IlvY compare
BWI76_RS21580 -1.1 -1.9 SsrA-binding protein compare
BWI76_RS24060 -1.1 -3.1 SprT family protein compare
BWI76_RS08500 -1.1 -2.8 cytochrome d ubiquinol oxidase subunit 2 compare
BWI76_RS06595 -1.1 -2.2 hypothetical protein compare
BWI76_RS12090 -1.1 -1.4 HNH endonuclease compare
BWI76_RS11580 -1.1 -2.3 L-asparaginase 1 compare
BWI76_RS22240 -1.1 -4.1 transcriptional regulator compare
BWI76_RS05680 -1.1 -3.7 LacI family transcriptional regulator compare
BWI76_RS09520 -1.1 -2.3 arginine ABC transporter ATP-binding protein ArtP compare
BWI76_RS25600 -1.1 -1.0 tRNA-Thr compare
BWI76_RS22450 -1.1 -1.8 selenoprotein W-related protein compare
BWI76_RS00355 -1.1 -2.3 DNA polymerase I compare
BWI76_RS00180 -1.1 -1.9 F0F1 ATP synthase subunit epsilon compare
BWI76_RS15955 -1.0 -7.2 transcriptional regulator compare
BWI76_RS05120 -1.0 -4.5 bifunctional glycosyl transferase/transpeptidase compare
BWI76_RS06535 -1.0 -3.1 endopeptidase La compare
BWI76_RS16275 -1.0 -2.0 fumarate hydratase FumA compare
BWI76_RS27440 -1.0 -2.8 DNA helicase RecG compare
BWI76_RS07465 -1.0 -2.6 TetR family transcriptional regulator compare
BWI76_RS25975 -1.0 -5.0 phosphoribulokinase compare
BWI76_RS18090 -1.0 -2.6 phosphoribosylglycinamide formyltransferase 2 compare
BWI76_RS03225 -1.0 -5.2 transcriptional regulator compare
BWI76_RS15840 -1.0 -2.2 prophage protein compare
BWI76_RS15810 -1.0 -3.4 hypothetical protein compare
BWI76_RS11235 -1.0 -1.2 hypothetical protein compare
BWI76_RS13595 -1.0 -3.4 transcriptional regulator compare
BWI76_RS23320 -1.0 -1.3 hypothetical protein compare
BWI76_RS15830 -1.0 -1.7 hypothetical protein compare
BWI76_RS00440 -1.0 -1.3 CopG family transcriptional regulator compare
BWI76_RS27425 -1.0 -2.0 DNA-directed RNA polymerase subunit omega compare
BWI76_RS07675 -1.0 -2.5 DeoR family transcriptional regulator compare
BWI76_RS22690 -1.0 -2.9 adenylyl-sulfate kinase compare
BWI76_RS27075 -1.0 -3.6 IclR family transcriptional regulator compare
BWI76_RS06340 -1.0 -1.1 hypothetical protein compare
BWI76_RS26440 -0.9 -1.2 hypothetical protein compare
BWI76_RS16090 -0.9 -1.8 two-component system response regulator DcuR compare
BWI76_RS07780 -0.9 -1.3 hypothetical protein compare
BWI76_RS26390 -0.9 -3.5 cell division protein FtsX compare
BWI76_RS20380 -0.9 -1.0 tRNA pseudouridine(38-40) synthase TruA compare
BWI76_RS21685 -0.9 -1.3 hypothetical protein compare
BWI76_RS27175 -0.9 -1.7 hypothetical protein compare
BWI76_RS21165 -0.9 -1.6 Fe-S cluster assembly transcriptional regulator IscR compare
BWI76_RS13435 -0.9 -1.5 hypothetical protein compare
BWI76_RS03665 -0.9 -1.5 ABC transporter ATP-binding protein compare
BWI76_RS23030 -0.9 -1.8 cobalamin biosynthesis protein CbiM compare
BWI76_RS01350 -0.9 -0.8 NAD(P)H-flavin reductase compare
BWI76_RS09025 -0.9 -1.3 GntR family transcriptional regulator compare
BWI76_RS06495 -0.9 -4.0 cytochrome ubiquinol oxidase subunit II compare


Specific Phenotypes

For 1 genes in this experiment

For carbon source L-Alanine in Klebsiella michiganensis M5al

For carbon source L-Alanine across organisms