Experiment set5IT057 for Sphingomonas koreensis DSMZ 15582

Compare to:

LB with D-Cycloserine 0.064 mg/ml

200 most detrimental genes:

  gene name fitness t score description  
Ga0059261_2119 +1.7 6.2 Flagellar motor protein compare
Ga0059261_2120 +1.6 5.7 hypothetical protein compare
Ga0059261_2121 +1.4 10.6 hypothetical protein compare
Ga0059261_2118 +1.3 8.2 flagellar motor stator protein MotA compare
Ga0059261_3948 +1.1 4.2 type II secretion system protein H compare
Ga0059261_2117 +1.0 8.5 Transposase and inactivated derivatives compare
Ga0059261_2124 +0.9 5.3 hypothetical protein compare
Ga0059261_2400 +0.9 5.3 Uncharacterized conserved protein compare
Ga0059261_2403 +0.9 4.5 hypothetical protein compare
Ga0059261_2125 +0.8 5.4 ATP-dependent helicase HrpB compare
Ga0059261_2547 +0.8 1.5 tRNA compare
Ga0059261_2402 +0.8 6.7 phage portal protein, HK97 family compare
Ga0059261_2132 +0.8 3.0 transcriptional regulator, BadM/Rrf2 family compare
Ga0059261_1527 +0.8 2.0 hypothetical protein compare
Ga0059261_2115 +0.8 7.0 transcriptional regulator, TetR family compare
Ga0059261_2116 +0.8 6.7 Integrase compare
Ga0059261_2404 +0.7 5.8 Protein of unknown function (DUF2793)/Caudovirus prohead protease compare
Ga0059261_2408 +0.7 6.3 Acetyltransferases compare
Ga0059261_2406 +0.7 5.4 Glutathione-dependent formaldehyde-activating enzyme compare
Ga0059261_2131 +0.7 4.2 large conductance mechanosensitive channel protein compare
Ga0059261_3944 +0.7 4.1 hypothetical protein compare
Ga0059261_2126 +0.7 3.2 ETC complex I subunit conserved region compare
Ga0059261_3957 +0.7 4.2 prepilin-type N-terminal cleavage/methylation domain compare
Ga0059261_0083 +0.7 1.6 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B (EC 6.3.5.-) compare
Ga0059261_1311 +0.6 3.4 Nitroreductase compare
Ga0059261_2129 +0.6 3.8 Beta-propeller domains of methanol dehydrogenase type compare
Ga0059261_3952 +0.6 4.7 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB compare
Ga0059261_2114 +0.6 6.1 Outer membrane receptor proteins, mostly Fe transport compare
Ga0059261_2113 +0.6 5.3 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) compare
Ga0059261_2407 +0.6 4.3 AraC-type DNA-binding domain-containing proteins compare
Ga0059261_2128 +0.6 2.8 Predicted membrane protein compare
Ga0059261_2396 +0.6 3.6 hypothetical protein compare
Ga0059261_2130 +0.6 4.8 Uncharacterized conserved protein compare
Ga0059261_3940 +0.6 3.8 hypothetical protein compare
Ga0059261_1904 +0.6 2.1 Asparaginase compare
Ga0059261_3941 +0.6 5.5 Predicted phosphatase compare
Ga0059261_2401 +0.6 5.1 Spermine/spermidine synthase compare
Ga0059261_2063 +0.6 3.1 Flagellar biosynthesis protein, FliO compare
Ga0059261_3945 +0.6 4.1 type II secretion system protein D compare
Ga0059261_2397 +0.6 4.4 Uncharacterized conserved protein compare
Ga0059261_2112 +0.6 4.8 Transcriptional regulator compare
Ga0059261_0770 +0.6 1.3 hypothetical protein compare
Ga0059261_3951 +0.6 4.0 Type II secretory pathway, component PulM compare
Ga0059261_2127 +0.6 3.7 NUDIX domain compare
Ga0059261_1799 +0.5 1.8 Uncharacterized protein conserved in bacteria (DUF2059) compare
Ga0059261_2390 +0.5 3.7 hypothetical protein compare
Ga0059261_2052 +0.5 2.8 siroheme synthase, N-terminal domain compare
Ga0059261_2134 +0.5 4.1 Beta-lactamase class C and other penicillin binding proteins compare
Ga0059261_2056 +0.5 4.0 Predicted acyl-CoA transferases/carnitine dehydratase compare
Ga0059261_3992 +0.5 2.1 Uncharacterized protein conserved in bacteria compare
Ga0059261_2077 +0.5 2.3 Uncharacterized protein conserved in bacteria compare
Ga0059261_2419 +0.5 3.6 Glutathione S-transferase compare
Ga0059261_2398 +0.5 2.9 hypothetical protein compare
Ga0059261_3949 +0.5 3.7 type II secretion system protein G compare
Ga0059261_3205 +0.5 3.9 transaminase, acetylornithine/succinylornithine family compare
Ga0059261_2395 +0.5 2.8 hypothetical protein compare
Ga0059261_3013 +0.5 2.3 transcriptional regulator, ArsR family compare
Ga0059261_0133 +0.5 1.7 GTP-binding protein HflX compare
Ga0059261_2135 +0.5 4.0 Zn-dependent alcohol dehydrogenases compare
Ga0059261_0889 +0.5 0.8 Cold shock proteins compare
Ga0059261_4060 +0.5 1.6 Predicted membrane protein compare
Ga0059261_2111 +0.5 4.3 Phosphodiesterase/alkaline phosphatase D compare
Ga0059261_2102 +0.5 2.4 hypothetical protein compare
Ga0059261_3950 +0.5 3.8 Type II secretion system (T2SS), protein L compare
Ga0059261_2136 +0.5 3.9 Transcriptional regulator compare
Ga0059261_3947 +0.5 1.2 type II secretion system protein I (GspI) compare
Ga0059261_3443 +0.5 2.9 hypothetical protein compare
Ga0059261_1278 +0.5 2.8 hypothetical protein compare
Ga0059261_3935 +0.4 3.4 hypothetical protein compare
Ga0059261_3931 +0.4 3.5 Predicted membrane protein/domain compare
Ga0059261_1146 +0.4 2.4 Flagellar basal body L-ring protein compare
Ga0059261_2399 +0.4 3.2 PilZ domain compare
Ga0059261_3206 +0.4 3.0 ornithine carbamoyltransferase compare
Ga0059261_2412 +0.4 3.7 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components compare
Ga0059261_3204 +0.4 3.0 hypothetical protein compare
Ga0059261_3934 +0.4 3.0 MoxR-like ATPases compare
Ga0059261_2411 +0.4 4.0 Uncharacterized protein conserved in bacteria compare
Ga0059261_2415 +0.4 3.5 Phytoene/squalene synthetase compare
Ga0059261_3201 +0.4 3.7 Metallo-beta-lactamase superfamily compare
Ga0059261_3197 +0.4 2.6 Acetyltransferases, including N-acetylases of ribosomal proteins compare
Ga0059261_1213 +0.4 1.3 hypothetical protein compare
Ga0059261_3946 +0.4 2.4 Type IV pilus biogenesis/PDZ domain compare
Ga0059261_3938 +0.4 2.9 Imidazolonepropionase and related amidohydrolases compare
Ga0059261_2059 +0.4 3.2 Flagellar biosynthesis pathway, component FlhB compare
Ga0059261_2393 +0.4 3.5 Predicted membrane protein compare
Ga0059261_2060 +0.4 3.0 flagellar biosynthetic protein FliR compare
Ga0059261_3198 +0.4 3.2 Beta-lactamase class A compare
Ga0059261_2109 +0.4 1.4 hypothetical protein compare
Ga0059261_2068 +0.4 2.1 hypothetical protein compare
Ga0059261_3646 +0.4 1.5 Uncharacterized stress protein (general stress protein 26) compare
Ga0059261_3280 +0.4 0.9 Uncharacterized conserved protein compare
Ga0059261_1145 +0.4 1.1 flagella basal body P-ring formation protein FlgA compare
Ga0059261_2053 +0.4 2.5 Mg2+ and Co2+ transporters compare
Ga0059261_3953 +0.4 3.1 Type II secretory pathway, component PulF compare
Ga0059261_3214 +0.4 2.7 hypothetical protein compare
Ga0059261_3937 +0.4 3.0 Imidazolonepropionase and related amidohydrolases compare
Ga0059261_2229 +0.4 1.4 Predicted transcriptional regulators compare
Ga0059261_2110 +0.4 3.4 Outer membrane receptor for ferrienterochelin and colicins compare
Ga0059261_2143 +0.4 2.1 Zn-dependent proteases compare
Ga0059261_2593 +0.4 1.6 hypothetical protein compare
Ga0059261_2987 +0.4 1.0 hypothetical protein compare
Ga0059261_3200 +0.4 3.1 Opacity protein and related surface antigens compare
Ga0059261_2058 +0.4 3.0 Flagellar capping protein compare
Ga0059261_2050 +0.4 1.7 hypothetical protein compare
Ga0059261_3936 +0.4 2.5 hypothetical protein compare
Ga0059261_3954 +0.3 2.9 Homoserine acetyltransferase compare
Ga0059261_3928 +0.3 1.9 Predicted thioesterase compare
Ga0059261_4013 +0.3 1.1 hypothetical protein compare
Ga0059261_2066 +0.3 3.0 Flagellar basal body-associated protein compare
Ga0059261_2387 +0.3 2.6 HIRAN domain compare
Ga0059261_2074 +0.3 2.6 Sigma-54 interaction domain/Bacterial regulatory protein, Fis family compare
Ga0059261_1214 +0.3 0.9 hypothetical protein compare
Ga0059261_3195 +0.3 2.7 Uncharacterized protein affecting Mg2+/Co2+ transport compare
Ga0059261_2137 +0.3 2.9 ABC-type multidrug transport system, ATPase and permease components compare
Ga0059261_1759 +0.3 1.6 Phosphoadenosine phosphosulfate reductase family compare
Ga0059261_3193 +0.3 2.9 Dolichyl-phosphate-mannose-protein mannosyltransferase compare
Ga0059261_2436 +0.3 2.0 hypothetical protein compare
Ga0059261_3579 +0.3 1.4 hypothetical protein compare
Ga0059261_0660 +0.3 2.0 Short-chain dehydrogenase involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) compare
Ga0059261_3624 +0.3 1.5 hypothetical protein compare
Ga0059261_3932 +0.3 2.7 Uncharacterized membrane protein compare
Ga0059261_3203 +0.3 2.7 ABC-type multidrug transport system, permease component compare
Ga0059261_2739 +0.3 1.5 heat-inducible transcription repressor HrcA compare
Ga0059261_4214 +0.3 0.9 Enoyl-CoA hydratase/carnithine racemase compare
Ga0059261_2144 +0.3 1.6 thymidine kinase (EC 2.7.1.21) compare
Ga0059261_3449 +0.3 2.3 G/U mismatch-specific uracil-DNA glycosylase (EC 3.2.2.-) compare
Ga0059261_2842 +0.3 2.0 SnoaL-like domain compare
Ga0059261_2384 +0.3 2.4 Phage capsid scaffolding protein (GPO) serine peptidase compare
Ga0059261_3604 +0.3 0.9 Uncharacterized protein conserved in bacteria compare
Ga0059261_2534 +0.3 1.3 3-hydroxyacyl-CoA dehydrogenase compare
Ga0059261_2047 +0.3 2.6 transcriptional regulator, TetR family compare
Ga0059261_0594 +0.3 1.8 RND family efflux transporter, MFP subunit compare
Ga0059261_3684 +0.3 1.6 hypothetical protein compare
Ga0059261_0586 +0.3 1.6 hypothetical protein compare
Ga0059261_2309 +0.3 1.8 transcriptional regulator, LacI family compare
Ga0059261_1707 +0.3 1.1 hypothetical protein compare
Ga0059261_3896 +0.3 0.9 integration host factor, beta subunit compare
Ga0059261_3194 +0.3 2.2 O-acetylhomoserine sulfhydrylase (EC:2.5.1.49) (from data) compare
Ga0059261_0557 +0.3 1.4 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Ga0059261_3026 +0.3 0.7 Cation efflux family compare
Ga0059261_0556 +0.3 1.4 Signal transduction histidine kinase compare
Ga0059261_3207 +0.3 1.6 Disulfide bond chaperones of the HSP33 family compare
Ga0059261_1406 +0.3 0.9 Acetyltransferase (GNAT) family compare
Ga0059261_0720 +0.3 1.2 Predicted small integral membrane protein compare
Ga0059261_2386 +0.3 2.6 phage portal protein, PBSX family compare
Ga0059261_3990 +0.3 1.9 hypothetical protein compare
Ga0059261_0274 +0.3 1.7 transcriptional regulator, TraR/DksA family compare
Ga0059261_0633 +0.3 1.0 Acetyltransferases, including N-acetylases of ribosomal proteins compare
Ga0059261_0656 +0.3 1.2 Predicted dehydrogenases and related proteins compare
Ga0059261_2347 +0.3 1.3 hypothetical protein compare
Ga0059261_3522 +0.3 1.5 Micrococcal nuclease (thermonuclease) homologs compare
Ga0059261_2057 +0.3 2.1 flagellar biosynthetic protein FliS compare
Ga0059261_2583 +0.3 1.9 Uncharacterized conserved protein (DUF2285) compare
Ga0059261_3800 +0.3 1.4 Cold shock proteins compare
Ga0059261_2389 +0.3 2.5 Predicted Co/Zn/Cd cation transporters compare
Ga0059261_2422 +0.3 1.6 Uncharacterized protein conserved in bacteria compare
Ga0059261_0593 +0.3 1.5 Outer membrane protein compare
Ga0059261_0455 +0.3 1.8 transcriptional regulator, AraC family compare
Ga0059261_3678 +0.3 1.8 Domain of unknown function (DUF4440) compare
Ga0059261_2320 +0.3 1.7 Uncharacterized relative of glutathione S-transferase, MAPEG superfamily compare
Ga0059261_0596 +0.3 1.6 Cation efflux family compare
Ga0059261_0579 +0.3 2.4 Neutral trehalase compare
Ga0059261_3224 +0.3 1.9 Acyl dehydratase compare
Ga0059261_2051 +0.3 2.3 diaminopimelate decarboxylase (EC 4.1.1.20) (from data) compare
Ga0059261_2049 +0.3 1.9 argininosuccinate lyase compare
Ga0059261_2277 +0.3 0.8 hypothetical protein compare
Ga0059261_0525 +0.3 0.9 Transcriptional regulator compare
Ga0059261_2929 +0.3 0.8 oxygen-dependent methionine synthase, methyltransferase component MesD (from data) compare
Ga0059261_3963 +0.3 2.0 Histidine ammonia-lyase (EC 4.3.1.3) (from data) compare
Ga0059261_2139 +0.3 2.0 Siderophore-interacting FAD-binding domain compare
Ga0059261_1811 +0.3 1.1 ATP:cob(I)alamin adenosyltransferase compare
Ga0059261_3226 +0.3 1.9 Uncharacterized protein conserved in bacteria compare
Ga0059261_1443 +0.3 2.1 Hemolysins and related proteins containing CBS domains compare
Ga0059261_1496 +0.3 1.3 uroporphyrin-III C-methyltransferase compare
Ga0059261_2108 +0.3 2.1 acetyl-CoA acetyltransferases compare
Ga0059261_0095 +0.3 1.6 Ribosomal protein L7/L12 C-terminal domain compare
Ga0059261_3165 +0.3 1.7 PEP phosphonomutase and related enzymes compare
Ga0059261_0266 +0.3 0.5 hypothetical protein compare
Ga0059261_1431 +0.3 1.0 hypothetical protein compare
Ga0059261_2045 +0.3 2.3 Sugar phosphate permease compare
Ga0059261_2142 +0.3 2.3 tRNA pseudouridine(55) synthase compare
Ga0059261_2069 +0.3 2.1 ATPase, FliI/YscN family compare
Ga0059261_1112 +0.3 1.7 hypothetical protein compare
Ga0059261_3303 +0.3 1.1 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) compare
Ga0059261_2640 +0.3 1.3 Asp/Glu/Hydantoin racemase compare
Ga0059261_3445 +0.3 1.9 PHP domain compare
Ga0059261_1022 +0.3 1.3 hypothetical protein compare
Ga0059261_1292 +0.3 0.7 hypothetical protein compare
Ga0059261_3622 +0.3 1.6 hypothetical protein compare
Ga0059261_2351 +0.3 1.1 hypothetical protein compare
Ga0059261_2041 +0.3 2.0 Short-chain alcohol dehydrogenase of unknown specificity compare
Ga0059261_3933 +0.2 1.7 Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) compare
Ga0059261_1075 +0.2 0.7 Uncharacterized protein conserved in bacteria compare
Ga0059261_2054 +0.2 2.0 Response regulator receiver domain compare
Ga0059261_1138 +0.2 1.0 hypothetical protein compare
Ga0059261_0065 +0.2 1.6 ABC-type dipeptide transport system, periplasmic component compare
Ga0059261_3027 +0.2 0.9 Predicted transcriptional regulators compare
Ga0059261_1035 +0.2 0.7 hypothetical protein compare
Ga0059261_2072 +0.2 1.7 flagellar basal-body M-ring protein/flagellar hook-basal body protein (fliF) compare
Ga0059261_1577 +0.2 2.2 L-glutamine and L-histidine transporter (from data) compare


Specific Phenotypes

For 1 genes in this experiment

For stress D-Cycloserine in Sphingomonas koreensis DSMZ 15582

For stress D-Cycloserine across organisms