Experiment set5IT055 for Pseudomonas fluorescens FW300-N2E2

Compare to:

LB with Hydroxylamine hydrochloride 0.5 M

200 most detrimental genes:

  gene name fitness t score description  
Pf6N2E2_2428 +4.9 8.7 Thiol-disulfide isomerase and thioredoxins compare
Pf6N2E2_2552 +4.8 11.1 Cytochrome c heme lyase subunit CcmH compare
Pf6N2E2_634 +4.1 27.9 NAD-specific glutamate dehydrogenase (EC 1.4.1.2), large form compare
Pf6N2E2_5554 +3.6 20.3 FIG023103: Predicted transmembrane protein compare
Pf6N2E2_4803 +3.4 6.3 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
Pf6N2E2_2527 +3.4 14.8 Oxidoreductase, short chain dehydrogenase/reductase family compare
Pf6N2E2_5130 +3.2 2.4 hypothetical protein compare
Pf6N2E2_3672 +3.2 19.3 Glutamate-ammonia-ligase adenylyltransferase (EC 2.7.7.42) compare
Pf6N2E2_3885 +3.0 5.6 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) compare
Pf6N2E2_5317 +3.0 20.0 Cytochrome O ubiquinol oxidase subunit II (EC 1.10.3.-) compare
Pf6N2E2_3261 +2.7 10.4 hypothetical protein compare
Pf6N2E2_3304 +2.7 9.9 probable periplasmic protein NMA1059 compare
Pf6N2E2_5156 +2.6 6.7 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_4418 +2.5 2.1 Diaminopimelate epimerase (EC 5.1.1.7) compare
Pf6N2E2_2526 +2.5 2.4 Similar to phosphoglycolate phosphatase, clustered with ubiquinone biosynthesis SAM-dependent O-methyltransferase compare
Pf6N2E2_2518 +2.5 2.6 Cyclohexadienyl dehydrogenase (EC 1.3.1.12)(EC 1.3.1.43) / 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19) compare
Pf6N2E2_5318 +2.4 20.1 Cytochrome O ubiquinol oxidase subunit I (EC 1.10.3.-) compare
Pf6N2E2_5321 +2.4 14.1 Heme O synthase, protoheme IX farnesyltransferase (EC 2.5.1.-) COX10-CtaB compare
Pf6N2E2_5320 +2.4 12.2 Cytochrome O ubiquinol oxidase subunit IV (EC 1.10.3.-) compare
Pf6N2E2_3541 +2.3 4.2 Putative multicopper oxidases compare
Pf6N2E2_2872 +2.3 15.8 Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) compare
Pf6N2E2_4452 +2.3 5.1 Porphobilinogen synthase (EC 4.2.1.24) compare
Pf6N2E2_2534 +2.2 5.4 Cell division protein BolA compare
Pf6N2E2_5319 +2.2 10.7 Cytochrome O ubiquinol oxidase subunit III (EC 1.10.3.-) compare
Pf6N2E2_4433 +2.1 10.8 Uncharacterized protein EC-HemY, likely associated with heme metabolism based on gene clustering with hemC, hemD in Proteobacteria (unrelated to HemY-type PPO in GramPositives) compare
Pf6N2E2_1696 +2.1 1.4 Alkanesulfonates-binding protein compare
Pf6N2E2_3190 +2.0 5.3 Iron-sulfur cluster regulator IscR compare
Pf6N2E2_4987 +2.0 2.1 MaoC-like domain protein compare
Pf6N2E2_2438 +2.0 2.9 hypothetical protein compare
Pf6N2E2_2488 +2.0 1.7 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_3886 +1.9 4.5 ADP compounds hydrolase NudE (EC 3.6.1.-) compare
Pf6N2E2_5965 +1.9 1.2 transcriptional regulator compare
Pf6N2E2_2074 +1.9 2.5 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_4159 +1.9 4.1 Cytochrome c4 compare
Pf6N2E2_1617 +1.9 1.9 COG2199: FOG: GGDEF domain compare
Pf6N2E2_5662 +1.9 11.2 L-Arginine ABC transporter, permease protein AotM (from data) compare
Pf6N2E2_2309 +1.9 2.8 hypothetical protein compare
Pf6N2E2_624 +1.9 5.4 hypothetical protein PA3071 compare
Pf6N2E2_3899 +1.9 10.2 Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49) compare
Pf6N2E2_3856 +1.9 8.0 Lysine-arginine-ornithine-binding periplasmic protein precursor (TC 3.A.1.3.1) compare
Pf6N2E2_2795 +1.9 3.0 putative exported protein compare
Pf6N2E2_4432 +1.9 6.7 Uroporphyrinogen-III synthase (EC 4.2.1.75) compare
Pf6N2E2_2646 +1.8 2.9 FIG00953416: hypothetical protein compare
Pf6N2E2_2306 +1.8 6.4 Cytochrome c oxidase subunit CcoO (EC 1.9.3.1) compare
Pf6N2E2_5661 +1.8 9.2 L-Arginine ABC transporter, permease protein AotQ (from data) compare
Pf6N2E2_2176 +1.8 2.2 Amidases related to nicotinamidase compare
Pf6N2E2_2310 +1.8 11.3 Cytochrome c oxidase subunit CcoN (EC 1.9.3.1) compare
Pf6N2E2_5846 +1.8 10.8 Nucleoside ABC transporter, periplasmic nucleoside-binding protein compare
Pf6N2E2_5243 +1.8 2.7 hypothetical protein compare
Pf6N2E2_4181 +1.8 2.0 Organic hydroperoxide resistance protein compare
Pf6N2E2_3183 +1.7 4.0 Believed to be involved in assembly of Fe-S clusters compare
Pf6N2E2_2912 +1.7 2.3 FIG00954094: hypothetical protein compare
Pf6N2E2_5660 +1.6 7.0 L-Arginine ABC transporter, periplasmic substrate-binding component (from data) compare
Pf6N2E2_5067 +1.6 7.1 MFS general substrate transporter compare
Pf6N2E2_625 +1.6 5.2 MoxR-like ATPase in aerotolerance operon compare
Pf6N2E2_525 +1.6 5.7 C4-type zinc finger protein, DksA/TraR family compare
Pf6N2E2_2699 +1.6 6.7 Fe(2+)/alpha-ketoglutarate-dependent dioxygenase LpxO compare
Pf6N2E2_4554 +1.6 10.1 Thiol-disulfide isomerase and thioredoxins compare
Pf6N2E2_5714 +1.5 2.5 Flavoprotein WrbA compare
Pf6N2E2_1040 +1.5 1.6 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) compare
Pf6N2E2_6047 +1.5 1.6 hypothetical protein compare
Pf6N2E2_5845 +1.5 5.3 Nucleoside ABC transporter, periplasmic nucleoside-binding protein compare
Pf6N2E2_4459 +1.5 1.3 Transcriptional regulator, GntR family compare
Pf6N2E2_5425 +1.5 1.6 hypothetical protein compare
Pf6N2E2_2180 +1.5 2.9 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
Pf6N2E2_1022 +1.4 2.2 Butyryl-CoA dehydrogenase (EC 1.3.99.2) compare
Pf6N2E2_3351 +1.4 5.2 tRNA pseudouridine synthase B (EC 4.2.1.70) compare
Pf6N2E2_5340 +1.4 3.3 Stringent starvation protein A compare
Pf6N2E2_4747 +1.4 3.6 Transmembrane sensor compare
Pf6N2E2_2313 +1.4 3.7 Cytochrome c oxidase subunit CcoP (EC 1.9.3.1) compare
Pf6N2E2_5316 +1.4 2.9 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf6N2E2_314 +1.4 1.7 Isochorismatase (EC 3.3.2.1) compare
Pf6N2E2_6031 +1.3 2.9 hypothetical protein compare
Pf6N2E2_4048 +1.3 5.2 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_5170 +1.3 8.2 FIG00955330: hypothetical protein compare
Pf6N2E2_1014 +1.3 1.5 Nitrate/nitrite transporter compare
Pf6N2E2_2693 +1.3 0.9 3-oxoacyl-[acyl-carrier-protein] synthase, KASIII (EC 2.3.1.180) compare
Pf6N2E2_5772 +1.3 2.6 DUF1232 domain-containing protein compare
Pf6N2E2_500 +1.3 2.0 Beta-ureidopropionase (EC 3.5.1.6) compare
Pf6N2E2_621 +1.3 5.1 TPR domain protein in aerotolerance operon compare
Pf6N2E2_1997 +1.3 2.9 FIG00956406: hypothetical protein compare
Pf6N2E2_3568 +1.3 1.9 Unsaturated fatty acid biosythesis repressor FabR, TetR family compare
Pf6N2E2_3346 +1.3 5.5 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
Pf6N2E2_578 +1.3 3.4 Mobile element protein compare
Pf6N2E2_4107 +1.3 6.7 Cytochrome oxidase biogenesis protein Sco1/SenC/PrrC, putative copper metallochaperone compare
Pf6N2E2_2308 +1.3 6.8 Cytochrome c oxidase subunit CcoP (EC 1.9.3.1) compare
Pf6N2E2_5864 +1.3 4.0 FIG00953296: hypothetical protein compare
Pf6N2E2_620 +1.2 5.7 BatD compare
Pf6N2E2_2286 +1.2 2.6 FIG00953287: hypothetical protein compare
Pf6N2E2_2823 +1.2 2.7 Multidrug efflux RND membrane fusion protein MexC compare
Pf6N2E2_5175 +1.2 8.8 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_3542 +1.2 7.8 Outer membrane receptor proteins, mostly Fe transport compare
Pf6N2E2_1497 +1.2 2.7 D-2-hydroxyglutarate dehydrogenase compare
Pf6N2E2_187 +1.2 1.8 Urea ABC transporter, ATPase protein UrtE compare
Pf6N2E2_4052 +1.2 1.3 FIG00955481: hypothetical protein compare
Pf6N2E2_3550 +1.2 2.4 Urea ABC transporter, ATPase protein UrtD compare
Pf6N2E2_5664 +1.2 5.7 Arginine pathway regulatory protein ArgR, repressor of arg regulon compare
Pf6N2E2_3589 +1.2 2.5 Lysine decarboxylase family compare
Pf6N2E2_241 +1.2 1.2 hypothetical protein compare
Pf6N2E2_5663 +1.2 4.2 L-Arginine ABC transporter, ATPase component (from data) compare
Pf6N2E2_622 +1.1 2.8 BatA (Bacteroides aerotolerance operon) compare
Pf6N2E2_3825 +1.1 3.4 Nitrogen regulation protein NtrB (EC 2.7.13.3) compare
Pf6N2E2_5794 +1.1 1.8 Ribosomal large subunit pseudouridine synthase A (EC 4.2.1.70) compare
Pf6N2E2_1670 +1.1 2.1 conserved membrane protein compare
Pf6N2E2_88 +1.1 1.2 hypothetical protein compare
Pf6N2E2_2088 +1.1 1.6 SOS-response repressor and protease LexA (EC 3.4.21.88) compare
Pf6N2E2_5158 +1.1 2.7 FIG00954153: hypothetical protein compare
Pf6N2E2_2824 +1.1 6.4 RND efflux system, inner membrane transporter CmeB compare
Pf6N2E2_5257 +1.1 5.6 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) compare
Pf6N2E2_2789 +1.1 1.4 L-lysine permease compare
Pf6N2E2_2069 +1.1 1.4 FIG00953703: hypothetical protein compare
Pf6N2E2_2124 +1.1 0.8 Mg(2+) transport ATPase protein C compare
Pf6N2E2_715 +1.1 2.2 putative membrane protein compare
Pf6N2E2_1896 +1.1 1.9 hypothetical protein compare
Pf6N2E2_3855 +1.1 5.3 Histidine ABC transporter, ATP-binding protein HisP (TC 3.A.1.3.1) compare
Pf6N2E2_3752 +1.1 8.2 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_5902 +1.1 1.8 hypothetical protein compare
Pf6N2E2_2535 +1.1 4.1 FIG00954136: hypothetical protein compare
Pf6N2E2_1613 +1.1 2.2 short-chain dehydrogenase/reductase compare
Pf6N2E2_2386 +1.1 3.1 Magnesium and cobalt transport protein CorA compare
Pf6N2E2_2798 +1.1 2.7 Death on curing protein, Doc toxin compare
Pf6N2E2_2305 +1.1 6.2 Cytochrome c oxidase subunit CcoN (EC 1.9.3.1) compare
Pf6N2E2_2788 +1.1 0.6 Transcriptional regulator, AsnC family compare
Pf6N2E2_5499 +1.1 1.0 hypothetical protein compare
Pf6N2E2_34 +1.1 2.8 Cytosine deaminase (EC 3.5.4.1) compare
Pf6N2E2_4635 +1.1 3.9 ATP-dependent RNA helicase RhlE compare
Pf6N2E2_1247 +1.1 1.9 hypothetical protein compare
Pf6N2E2_1583 +1.1 2.2 ABC-type protease/lipase transport system, ATPase and permease components compare
Pf6N2E2_490 +1.1 2.1 PhaK-like protein compare
Pf6N2E2_3807 +1.1 3.1 Histidine utilization repressor compare
Pf6N2E2_5346 +1.0 2.6 rRNA small subunit methyltransferase I compare
Pf6N2E2_6081 +1.0 2.6 Transcriptional regulator, TetR family, in cluster with 2-hydroxychromene-2-carboxylate isomerase family protein, glutathione-dependent compare
Pf6N2E2_1605 +1.0 2.9 Carboxynorspermidine dehydrogenase, putative (EC 1.1.1.-) compare
Pf6N2E2_4172 +1.0 4.7 Methionine ABC transporter ATP-binding protein compare
Pf6N2E2_579 +1.0 1.3 FIG00962753: hypothetical protein compare
Pf6N2E2_3702 +1.0 1.4 FIG00953907: hypothetical protein compare
Pf6N2E2_1028 +1.0 1.7 Transcriptional regulator, LysR family compare
Pf6N2E2_5863 +1.0 2.1 FIG00956080: hypothetical protein compare
Pf6N2E2_5860 +1.0 5.0 Branched-chain amino acid transport system carrier protein compare
Pf6N2E2_4397 +1.0 2.4 Xanthine phosphoribosyltransferase (EC 2.4.2.22) compare
Pf6N2E2_5869 +1.0 2.0 Helicase subunit of the DNA excision repair complex compare
Pf6N2E2_2986 +1.0 2.2 Transcriptional regulator, LuxR family compare
Pf6N2E2_2293 +1.0 2.4 COG0488: ATPase components of ABC transporters with duplicated ATPase domains compare
Pf6N2E2_5555 +1.0 0.8 Cold shock protein CspA compare
Pf6N2E2_5632 +1.0 2.5 Aromatic amino acid transport protein AroP compare
Pf6N2E2_5961 +1.0 3.7 Transcriptional regulator, TetR family compare
Pf6N2E2_1386 +1.0 2.4 amino acid ABC transporter, periplasmic substrate-binding protein compare
Pf6N2E2_2007 +1.0 1.9 Error-prone, lesion bypass DNA polymerase V (UmuC) compare
Pf6N2E2_440 +1.0 1.2 FIG00954920: hypothetical protein compare
Pf6N2E2_5366 +1.0 2.2 DNA-binding heavy metal response regulator compare
Pf6N2E2_1293 +1.0 2.0 COG2879, Hypothetical small protein yjiX compare
Pf6N2E2_647 +1.0 1.5 General secretion pathway protein G compare
Pf6N2E2_4733 +1.0 1.2 hypothetical protein compare
Pf6N2E2_1316 +1.0 2.4 P-hydroxyphenylacetate hydroxylase C1:reductase component compare
Pf6N2E2_4342 +1.0 2.6 Protein phosphatase ImpM compare
Pf6N2E2_2580 +1.0 2.3 Flagellar biosynthesis protein FliP compare
Pf6N2E2_1566 +1.0 2.5 FIG00960770: hypothetical protein compare
Pf6N2E2_86 +1.0 2.1 FIG022160: hypothetical toxin compare
Pf6N2E2_5073 +1.0 1.2 Large-conductance mechanosensitive channel compare
Pf6N2E2_3110 +1.0 3.4 Putative lipoprotein in cluster with COG2110 compare
Pf6N2E2_3627 +0.9 4.1 Thiosulfate sulfurtransferase, rhodanese (EC 2.8.1.1) compare
Pf6N2E2_4169 +0.9 4.3 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_2582 +0.9 1.8 Flagellar motor switch protein FliN compare
Pf6N2E2_1714 +0.9 2.7 FIG01218476: hypothetical protein compare
Pf6N2E2_2642 +0.9 4.9 putative patatin-like phospholipase compare
Pf6N2E2_2335 +0.9 2.6 Transcriptional regulator, GntR family compare
Pf6N2E2_3171 +0.9 1.0 hypothetical protein compare
Pf6N2E2_4928 +0.9 1.3 Permeases of the major facilitator superfamily compare
Pf6N2E2_5327 +0.9 2.0 Outer membrane protein assembly factor YaeT precursor compare
Pf6N2E2_4121 +0.9 1.6 Ribosomal RNA small subunit methyltransferase B (EC 2.1.1.-) compare
Pf6N2E2_5861 +0.9 4.0 FIG00953885: hypothetical protein compare
Pf6N2E2_3238 +0.9 3.0 TRAP-type C4-dicarboxylate transport system, periplasmic component compare
Pf6N2E2_3829 +0.9 4.0 Protein export cytoplasm chaperone protein (SecB, maintains protein to be exported in unfolded state) compare
Pf6N2E2_2311 +0.9 5.2 Cytochrome c oxidase subunit CcoO (EC 1.9.3.1) compare
Pf6N2E2_603 +0.9 1.6 FIG00953934: hypothetical protein compare
Pf6N2E2_3844 +0.9 1.3 hypothetical protein compare
Pf6N2E2_1723 +0.9 1.9 Transcriptional regulator, TetR family compare
Pf6N2E2_4305 +0.9 0.8 FIG00959590: hypothetical protein compare
Pf6N2E2_3275 +0.9 2.7 FOG: TPR repeat compare
Pf6N2E2_2591 +0.9 2.6 Flagellar assembly protein FliH compare
Pf6N2E2_495 +0.9 1.5 YD repeat protein compare
Pf6N2E2_3014 +0.9 1.2 P2-like prophage tail protein X compare
Pf6N2E2_1482 +0.9 3.0 Probable periplasmic spermidine/putrescine-binding protein compare
Pf6N2E2_3799 +0.9 2.1 Histidine ammonia-lyase (EC 4.3.1.3) (from data) compare
Pf6N2E2_4248 +0.9 3.2 SAM-dependent methyltransferases compare
Pf6N2E2_5176 +0.9 3.4 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_4334 +0.9 3.0 Uncharacterized protein ImpC compare
Pf6N2E2_3539 +0.9 1.2 FIG00955840: hypothetical protein compare
Pf6N2E2_4579 +0.9 0.9 Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) compare
Pf6N2E2_2694 +0.9 4.0 ATP-dependent RNA helicase HrpA (EC 3.6.4.13) compare
Pf6N2E2_3826 +0.9 2.6 Nitrogen regulation protein NR(I) compare
Pf6N2E2_1746 +0.9 1.9 Spermidine Putrescine ABC transporter permease component potC (TC_3.A.1.11.1) compare
Pf6N2E2_2181 +0.9 1.2 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf6N2E2_1844 +0.9 1.9 MaoC-related acyl dehydratase compare
Pf6N2E2_3630 +0.8 2.4 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_1666 +0.8 1.5 Transcriptional regulator, LysR family compare
Pf6N2E2_1477 +0.8 2.2 hypothetical protein compare
Pf6N2E2_204 +0.8 1.0 hypothetical protein compare
Pf6N2E2_1328 +0.8 2.5 Methyl-accepting chemotaxis protein compare
Pf6N2E2_3062 +0.8 1.9 Membrane-associated zinc metalloprotease compare


Specific Phenotypes

For 24 genes in this experiment

For stress Hydroxylamine hydrochloride in Pseudomonas fluorescens FW300-N2E2

For stress Hydroxylamine hydrochloride across organisms