Experiment set5IT055 for Klebsiella michiganensis M5al

Compare to:

L-Malic acid disodium salt monohydrate carbon source

200 most detrimental genes:

  gene name fitness t score description  
BWI76_RS24575 +1.8 2.7 hypothetical protein compare
BWI76_RS21245 +1.4 4.6 nitrogen regulatory protein P-II compare
BWI76_RS15215 +1.2 1.7 N-acetyltransferase compare
BWI76_RS17805 +1.2 2.0 membrane protein compare
BWI76_RS17045 +1.1 1.9 hypothetical protein compare
BWI76_RS16675 +1.1 2.8 ABC transporter compare
BWI76_RS20785 +1.0 1.8 ethanolamine utilization protein EutJ compare
BWI76_RS20795 +1.0 1.4 ethanolamine catabolic microcompartment shell protein EutN compare
BWI76_RS09690 +0.9 2.5 dimethyl sulfoxide reductase compare
BWI76_RS04565 +0.9 2.8 bifunctional tRNA pseudouridine(32) synthase/ribosomal large subunit pseudouridine synthase RluA compare
BWI76_RS09560 +0.9 2.2 DoxX family membrane protein compare
BWI76_RS13250 +0.9 1.3 cytochrome b561 compare
BWI76_RS17200 +0.9 1.7 hypothetical protein compare
BWI76_RS00750 +0.9 2.7 ATP-dependent protease ATP-binding subunit HslU compare
BWI76_RS24920 +0.9 1.9 YraN family protein compare
BWI76_RS23125 +0.9 1.0 propanediol dehydratase small subunit compare
BWI76_RS12040 +0.9 1.3 hypothetical protein compare
BWI76_RS13785 +0.9 1.7 ABC transporter permease compare
BWI76_RS11775 +0.8 2.2 2-deoxy-D-gluconate 3-dehydrogenase compare
BWI76_RS26330 +0.8 3.4 ABC transporter ATP-binding protein compare
BWI76_RS03180 +0.8 1.4 phage transcriptional regulator, AlpA compare
BWI76_RS09830 +0.8 2.0 tRNA uridine 5-oxyacetic acid(34) methyltransferase CmoM compare
BWI76_RS09305 +0.8 3.2 hypothetical protein compare
BWI76_RS08735 +0.8 2.3 Urocanate hydratase (EC 4.2.1.49) (from data) compare
BWI76_RS20560 +0.8 2.0 hypothetical protein compare
BWI76_RS21740 +0.8 2.0 transcriptional regulator, LysR family protein compare
BWI76_RS12875 +0.8 1.4 bifunctional deaminase-reductase compare
BWI76_RS01630 +0.8 1.2 16S ribosomal RNA compare
BWI76_RS15365 +0.8 3.5 hypothetical protein compare
BWI76_RS06475 +0.8 1.3 protoheme IX farnesyltransferase compare
BWI76_RS22935 +0.8 1.5 L-fucose mutarotase compare
BWI76_RS25935 +0.8 3.1 glutathione-regulated potassium-efflux system ancillary protein KefG compare
BWI76_RS11895 +0.8 2.7 AraC family transcriptional regulator compare
BWI76_RS13300 +0.8 3.0 carboxylesterase compare
BWI76_RS11700 +0.8 1.1 hypothetical protein compare
BWI76_RS07255 +0.8 2.4 hypothetical protein compare
BWI76_RS21165 +0.8 1.8 Fe-S cluster assembly transcriptional regulator IscR compare
BWI76_RS05790 +0.7 1.6 phage DNA-binding protein compare
BWI76_RS16115 +0.7 2.6 fumarate hydratase compare
BWI76_RS20050 +0.7 1.4 hypothetical protein compare
BWI76_RS14980 +0.7 1.7 hypothetical protein compare
BWI76_RS22090 +0.7 1.5 transcriptional regulator compare
BWI76_RS23245 +0.7 1.3 hypothetical protein compare
BWI76_RS15035 +0.7 0.7 metal ABC transporter permease compare
BWI76_RS18335 +0.7 4.4 DNA-binding response regulator compare
BWI76_RS02180 +0.7 0.8 hypothetical protein compare
BWI76_RS16140 +0.7 2.4 3-oxoadipate CoA-transferase compare
BWI76_RS20145 +0.7 1.5 NADH-quinone oxidoreductase subunit K compare
BWI76_RS18235 +0.7 1.8 trehalose-phosphatase compare
BWI76_RS24270 +0.7 1.2 membrane protein compare
BWI76_RS03105 +0.7 0.9 myo-inosose-2 dehydratase compare
BWI76_RS15150 +0.7 2.2 outer membrane efflux protein compare
BWI76_RS13420 +0.7 0.9 ABC transporter permease compare
BWI76_RS19310 +0.7 1.2 ABC transporter permease compare
BWI76_RS15120 +0.7 3.2 hypothetical protein compare
BWI76_RS11900 +0.7 1.1 cob(I)yrinic acid a,c-diamide adenosyltransferase compare
BWI76_RS01335 +0.6 3.1 DNase TatD compare
BWI76_RS15930 +0.6 1.8 dimethylsulfoxide reductase, chain B compare
BWI76_RS07760 +0.6 1.5 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase compare
BWI76_RS14670 +0.6 1.2 hypothetical protein compare
BWI76_RS10435 +0.6 2.1 suppressor for copper-sensitivity C compare
BWI76_RS10735 +0.6 1.6 hypothetical protein compare
BWI76_RS04600 +0.6 1.8 inner membrane protein compare
BWI76_RS24380 +0.6 2.6 esterase YqiA compare
BWI76_RS21015 +0.6 3.0 LysR family transcriptional regulator compare
BWI76_RS21915 +0.6 3.6 short-chain dehydrogenase/reductase SDR compare
BWI76_RS19695 +0.6 1.7 membrane protein compare
BWI76_RS16900 +0.6 0.9 4-hydroxy-2-oxovalerate aldolase compare
BWI76_RS15965 +0.6 2.7 MFS transporter compare
BWI76_RS15950 +0.6 1.4 dethiobiotin synthase compare
BWI76_RS15975 +0.6 1.0 hypothetical protein compare
BWI76_RS27745 +0.6 1.3 PTS sugar transporter subunit IIB compare
BWI76_RS06630 +0.6 2.9 hypothetical protein compare
BWI76_RS16910 +0.6 1.6 2-keto-4-pentenoate hydratase compare
BWI76_RS27225 +0.6 2.1 rhodanese-like domain-containing protein compare
BWI76_RS18240 +0.6 1.4 L-arabinose ABC transporter permease AraH compare
BWI76_RS11180 +0.6 2.6 hypothetical protein compare
BWI76_RS15795 +0.6 2.2 bacteriophage CII family protein compare
BWI76_RS19770 +0.6 1.2 bifunctional murein DD-endopeptidase/murein LD-carboxypeptidase compare
BWI76_RS26285 +0.6 2.6 glycerophosphodiester phosphodiesterase compare
BWI76_RS05785 +0.6 1.0 CI repressor compare
BWI76_RS08650 +0.6 1.8 molybdate ABC transporter permease compare
BWI76_RS09940 +0.6 1.2 paraquat-inducible protein B compare
BWI76_RS22205 +0.6 1.6 cation ABC transporter ATP-binding protein compare
BWI76_RS16920 +0.6 1.4 3-(2,3-dihydroxyphenyl)propionate dioxygenase compare
BWI76_RS09895 +0.6 1.8 aliphatic sulfonates ABC transporter ATP-binding protein compare
BWI76_RS13215 +0.6 1.0 type I glyceraldehyde-3-phosphate dehydrogenase compare
BWI76_RS06065 +0.6 2.4 taurine ABC transporter substrate-binding protein compare
BWI76_RS05045 +0.6 1.0 general secretion pathway protein GspM compare
BWI76_RS20610 +0.6 1.6 LysR family transcriptional regulator compare
BWI76_RS06265 +0.6 1.8 antibiotic biosynthesis monooxygenase compare
BWI76_RS10245 +0.6 1.1 aspartate aminotransferase compare
BWI76_RS12050 +0.6 2.1 hypothetical protein compare
BWI76_RS07595 +0.6 1.8 putative oxidoreductase compare
BWI76_RS00740 +0.6 2.1 ribonuclease E activity regulator RraA compare
BWI76_RS25415 +0.6 2.3 GntR family transcriptional regulator compare
BWI76_RS18810 +0.6 1.4 nitrogenase iron protein compare
BWI76_RS12870 +0.6 1.6 putative phytanoyl-CoA dioxygenase compare
BWI76_RS18225 +0.6 2.0 universal stress protein C compare
BWI76_RS13360 +0.6 3.4 benzoate transporter compare
BWI76_RS17155 +0.6 1.0 hypothetical protein compare
BWI76_RS17470 +0.6 1.3 MerR family transcriptional regulator compare
BWI76_RS21910 +0.6 1.6 glyoxylate/hydroxypyruvate reductase A compare
BWI76_RS08275 +0.6 0.8 LexA regulated protein compare
BWI76_RS16450 +0.6 2.6 fusaric acid resistance protein compare
BWI76_RS27455 +0.6 1.3 DUF805 domain-containing protein compare
BWI76_RS18535 +0.6 2.8 alpha/beta hydrolase compare
BWI76_RS16665 +0.6 2.2 ABC transporter permease compare
BWI76_RS19615 +0.5 1.7 vancomycin high temperature exclusion protein compare
BWI76_RS21235 +0.5 1.0 hypothetical protein compare
BWI76_RS16485 +0.5 0.8 ribonuclease T compare
BWI76_RS02920 +0.5 1.6 addiction module toxin RelE compare
BWI76_RS09570 +0.5 2.2 hydroxylamine reductase compare
BWI76_RS25375 +0.5 0.9 hypothetical protein compare
BWI76_RS10295 +0.5 1.3 short chain dehydrogenase/reductase family oxidoreductase compare
BWI76_RS22620 +0.5 1.7 3-octaprenyl-4-hydroxybenzoate carboxy-lyase compare
BWI76_RS16795 +0.5 1.6 amino acid ABC transporter ATPase compare
BWI76_RS26210 +0.5 2.8 glycogen debranching enzyme compare
BWI76_RS07740 +0.5 1.0 Fe2+-enterobactin ABC transporter substrate-binding protein compare
BWI76_RS00790 +0.5 2.1 bifunctional aspartokinase II/homoserine dehydrogenase II compare
BWI76_RS26280 +0.5 1.4 hypothetical protein compare
BWI76_RS11345 +0.5 1.4 LysR family transcriptional regulator compare
BWI76_RS00090 +0.5 2.5 multidrug transporter subunit MdtL compare
BWI76_RS12510 +0.5 2.9 peptide ABC transporter substrate-binding protein compare
BWI76_RS05985 +0.5 2.6 branched-chain amino acid ABC transporter permease compare
BWI76_RS16680 +0.5 1.8 ABC transporter substrate-binding protein compare
BWI76_RS12480 +0.5 1.5 TIGR01620 family protein compare
BWI76_RS18755 +0.5 0.8 adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase compare
BWI76_RS15315 +0.5 2.3 DNA-binding protein compare
BWI76_RS15800 +0.5 1.3 transcriptional regulator compare
BWI76_RS13020 +0.5 2.5 NmrA family protein compare
BWI76_RS10450 +0.5 1.4 tRNA-Tyr compare
BWI76_RS16895 +0.5 0.9 3-(3-hydroxy-phenyl)propionate transporter MhpT compare
BWI76_RS25450 +0.5 1.8 p-hydroxybenzoic acid efflux subunit AaeA compare
BWI76_RS13820 +0.5 1.7 hypothetical protein compare
BWI76_RS27005 +0.5 1.6 hypothetical protein compare
BWI76_RS26525 +0.5 1.3 nickel-responsive transcriptional regulator NikR compare
BWI76_RS10580 +0.5 1.7 amino acid ABC transporter permease compare
BWI76_RS08600 +0.5 2.5 3-deoxy-7-phosphoheptulonate synthase compare
BWI76_RS08250 +0.5 2.0 tricarballylate utilization protein B compare
BWI76_RS02700 +0.5 2.9 D-serine/D-alanine/glycine transporter compare
BWI76_RS03905 +0.5 1.7 2-oxo-3-deoxygalactonate kinase compare
BWI76_RS24470 +0.5 2.7 hypothetical protein compare
BWI76_RS11835 +0.5 1.0 putative regulatory protein MarR compare
BWI76_RS11585 +0.5 1.6 signal peptide peptidase A compare
BWI76_RS10475 +0.5 1.6 binding-protein-dependent transport system inner membrane protein compare
BWI76_RS01995 +0.5 0.6 AraC family transcriptional regulator compare
BWI76_RS08350 +0.5 1.0 carboxylase compare
BWI76_RS26920 +0.5 1.6 DNA-3-methyladenine glycosylase I compare
BWI76_RS11490 +0.5 2.3 MltA-interacting protein MipA compare
BWI76_RS01560 +0.5 2.0 Rsd/AlgQ family anti-sigma factor compare
BWI76_RS17530 +0.5 1.3 hypothetical protein compare
BWI76_RS04895 +0.5 1.1 hypothetical protein compare
BWI76_RS23755 +0.5 1.5 transcriptional regulator compare
BWI76_RS19195 +0.5 1.9 nickel ABC transporter permease compare
BWI76_RS15015 +0.5 0.7 DUF2132 domain-containing protein compare
BWI76_RS07970 +0.5 0.9 hypothetical protein compare
BWI76_RS12470 +0.5 0.9 thiosulfate sulfurtransferase PspE compare
BWI76_RS21075 +0.5 0.6 membrane protein compare
BWI76_RS25410 +0.5 3.0 GntR family transcriptional regulator with compare
BWI76_RS15045 +0.5 1.4 LysR family transcriptional regulator compare
BWI76_RS11155 +0.5 1.3 penicillin-binding protein activator LpoB compare
BWI76_RS13895 +0.5 1.1 LysR family transcriptional regulator compare
BWI76_RS15345 +0.5 1.3 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase compare
BWI76_RS12585 +0.5 1.4 transcriptional regulator compare
BWI76_RS05235 +0.5 0.7 hypothetical protein compare
BWI76_RS15985 +0.5 1.8 LysR family transcriptional regulator compare
BWI76_RS10010 +0.5 3.7 hypothetical protein compare
BWI76_RS25435 +0.5 1.1 membrane protein compare
BWI76_RS25655 +0.5 1.7 DNA topoisomerase type IA zn finger domain-containing protein compare
BWI76_RS20055 +0.5 2.7 2-succinylbenzoate-CoA ligase compare
BWI76_RS27635 +0.5 1.0 AraC family transcriptional regulator compare
BWI76_RS14230 +0.5 1.2 flavin monoamine oxidase family protein compare
BWI76_RS10760 +0.5 0.9 nitroreductase family protein compare
BWI76_RS14575 +0.5 1.3 TENA/THI-4 family protein compare
BWI76_RS11410 +0.5 1.1 leucine efflux protein compare
BWI76_RS07755 +0.5 1.4 isochorismatase compare
BWI76_RS18360 +0.5 0.7 aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase family protein compare
BWI76_RS19935 +0.5 0.8 hypothetical protein compare
BWI76_RS07345 +0.5 2.0 family 3 extracellular solute-binding protein compare
BWI76_RS09160 +0.5 2.0 multidrug transporter MdfA compare
BWI76_RS08745 +0.5 1.6 proline-specific permease compare
BWI76_RS09935 +0.5 1.8 paraquat-inducible membrane protein A compare
BWI76_RS18415 +0.5 1.2 very short patch repair endonuclease compare
BWI76_RS08590 +0.5 1.7 zinc transporter ZitB compare
BWI76_RS11250 +0.5 0.6 spermidine/putrescine ABC transporter permease PotB compare
BWI76_RS23205 +0.5 2.2 propanediol utilization protein PduX compare
BWI76_RS27105 +0.5 2.2 3-keto-L-gulonate-6-phosphate decarboxylase compare
BWI76_RS18070 +0.5 0.9 DNA polymerase III subunit epsilon compare
BWI76_RS27680 +0.4 1.9 TetR family transcriptional regulator compare
BWI76_RS21340 +0.4 1.1 SoxR reducing system protein RseC compare
BWI76_RS00295 +0.4 2.9 transcriptional regulator RbsR compare
BWI76_RS22190 +0.4 2.5 hypothetical protein compare
BWI76_RS04010 +0.4 2.4 hypothetical protein compare
BWI76_RS15095 +0.4 2.0 isochorismatase compare
BWI76_RS20945 +0.4 1.2 uracil phosphoribosyltransferase compare
BWI76_RS03015 +0.4 0.9 RNase E inhibitor protein compare
BWI76_RS09080 +0.4 1.2 molybdopterin-synthase adenylyltransferase MoeB compare
BWI76_RS10430 +0.4 1.0 thiol:disulfide interchange protein DsbG compare
BWI76_RS12080 +0.4 0.9 hypothetical protein compare


Specific Phenotypes

None in this experiment

For Klebsiella michiganensis M5al in carbon source experiments

For carbon source L-Malic acid disodium salt monohydrate across organisms