Experiment set5IT054 for Methanococcus maripaludis S2

200 most important genes:

gene	name	fitness	t score	description
MMP_RS01240		-1.5	-2.8	7-cyano-7-deazaguanine synthase QueC
MMP_RS05920		-1.4	-1.1	50S ribosomal protein L37e
MMP_RS08300		-1.4	-1.5	metal-sulfur cluster assembly factor
MMP_RS02145		-1.4	-7.0	winged helix-turn-helix transcriptional regulator
MMP_RS01960		-1.4	-1.0	hypothetical protein
MMP_RS06175		-1.2	-5.0	winged helix-turn-helix transcriptional regulator
MMP_RS07380		-1.1	-2.1	transcription elongation factor Spt5
MMP_RS03340		-1.1	-1.0	ABC transporter ATP-binding protein
MMP_RS02280		-1.0	-1.1	DUF211 domain-containing protein
MMP_RS05535		-1.0	-3.6	hypothetical protein
MMP_RS07765		-1.0	-7.2	sodium:alanine symporter family protein
MMP_RS08745		-0.9	-4.4	CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase
MMP_RS08635		-0.9	-1.8	UbiA family prenyltransferase
MMP_RS07350		-0.9	-1.9	preprotein translocase subunit Sec61beta
MMP_RS01225		-0.9	-4.1	DUF5379 domain-containing protein
MMP_RS08650		-0.9	-2.1	glutamine--fructose-6-phosphate transaminase (isomerizing)
MMP_RS03445		-0.9	-1.0	methanogenesis marker 17 protein
MMP_RS07735		-0.8	-0.9	2-ketoisovalerate ferredoxin oxidoreductase subunit alpha
MMP_RS08820		-0.7	-3.2	hypothetical protein
MMP_RS06840		-0.7	-1.0	DNA-directed RNA polymerase subunit N
MMP_RS02900		-0.7	-0.5	imidazoleglycerol-phosphate dehydratase HisB
MMP_RS00515		-0.7	-0.5	DUF655 domain-containing protein
MMP_RS07845		-0.7	-2.2	LL-diaminopimelate aminotransferase
MMP_RS02240		-0.7	-2.3	methanogenesis marker 7 protein
MMP_RS02165		-0.7	-4.0	tRNA-dihydrouridine synthase
MMP_RS05280		-0.7	-3.6	COG1361 S-layer family protein
MMP_RS06120		-0.7	-1.4	UPF0147 family protein
MMP_RS01175		-0.7	-2.8	triphosphoribosyl-dephospho-CoA synthase
MMP_RS03110		-0.6	-3.5	glycosyltransferase family 2 protein
MMP_RS05515		-0.6	-2.7	cyclic pyranopterin monophosphate synthase MoaC
MMP_RS05510		-0.6	-3.7	Rrf2 family transcriptional regulator
MMP_RS01020		-0.6	-0.9	3 4-dihydroxy-2-butanone-4-phosphate synthase
MMP_RS01830		-0.6	-1.0	tRNA-Val
MMP_RS00750		-0.6	-2.0	fumarate hydratase
MMP_RS01365		-0.6	-2.1	archaeal proteasome endopeptidase complex subunit alpha
MMP_RS03315		-0.6	-1.0	ferrous iron transport protein A
MMP_RS00125		-0.6	-1.3	DUF2798 domain-containing protein
MMP_RS03520		-0.6	-1.7	YwbE family protein
MMP_RS01500		-0.6	-1.6	CBS domain-containing protein
MMP_RS08195		-0.6	-3.9	hypothetical protein
MMP_RS09055		-0.6	-0.8	CAP domain-containing protein
MMP_RS06735		-0.6	-2.6	class I SAM-dependent rRNA methyltransferase
MMP_RS06110		-0.6	-1.8	ATP-dependent protease LonB
MMP_RS01180		-0.6	-0.9	XTP/dITP diphosphatase
MMP_RS05875		-0.6	-1.9	hydroxyethylthiazole kinase
MMP_RS00115		-0.5	-3.6	radical SAM protein
MMP_RS08940		-0.5	-0.9	MetS family NSS transporter small subunit
MMP_RS08600		-0.5	-1.5	flagellar protein D
MMP_RS00320		-0.5	-1.0	class I SAM-dependent methyltransferase
MMP_RS08995		-0.5	-1.0	hypothetical protein
MMP_RS01720		-0.5	-1.0	replication factor C large subunit
MMP_RS02195		-0.5	-2.0	tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
MMP_RS04890		-0.5	-0.5	adenylyltransferase/cytidyltransferase family protein
MMP_RS01900		-0.5	-3.6	hypothetical protein
MMP_RS03020		-0.5	-1.7	peptidylprolyl isomerase
MMP_RS01100		-0.5	-1.2	ABC transporter ATP-binding protein
MMP_RS02605		-0.5	-0.7	MotA/TolQ/ExbB proton channel family protein
MMP_RS03025		-0.5	-2.7	molybdenum cofactor guanylyltransferase
MMP_RS05285		-0.5	-1.9	MMPL family transporter
MMP_RS03095		-0.5	-2.1	diphthine synthase
MMP_RS00345		-0.5	-2.7	DUF2666 domain-containing protein
MMP_RS00915		-0.5	-2.1	DUF116 domain-containing protein
MMP_RS07355		-0.5	-0.6	transcription factor S
MMP_RS00685		-0.5	-2.3	2-phospho-L-lactate guanylyltransferase
MMP_RS01645		-0.5	-1.2	SWIM zinc finger family protein
MMP_RS01195		-0.5	-0.9	metalloregulator ArsR/SmtB family transcription factor
MMP_RS07645		-0.5	-2.8	aldehyde dehydrogenase family protein
MMP_RS03965		-0.5	-1.4	hypothetical protein
MMP_RS08555		-0.5	-2.2	hypothetical protein
MMP_RS01430		-0.5	-2.7	mechanosensitive ion channel family protein
MMP_RS06540		-0.5	-1.3	3-methyl-2-oxobutanoate dehydrogenase subunit VorB
MMP_RS08370		-0.5	-0.4	cation:proton antiporter subunit C
MMP_RS07640		-0.5	-2.2	mechanosensitive ion channel family protein
MMP_RS03395		-0.5	-2.0	hypothetical protein
MMP_RS06555		-0.5	-1.4	cupin domain-containing protein
MMP_RS02450		-0.5	-1.7	hypothetical protein
MMP_RS06345		-0.5	-3.3	formate dehydrogenase accessory sulfurtransferase FdhD
MMP_RS08390		-0.4	-1.9	DUF5400 domain-containing protein
MMP_RS00895		-0.4	-1.8	hypothetical protein
MMP_RS05975		-0.4	-1.0	hypothetical protein
MMP_RS05140		-0.4	-2.0	helix-turn-helix transcriptional regulator
MMP_RS06865		-0.4	-1.3	HypC/HybG/HupF family hydrogenase formation chaperone
MMP_RS07815		-0.4	-0.8	DUF2120 domain-containing protein
MMP_RS03400		-0.4	-1.2	archease
MMP_RS00950		-0.4	-1.6	site-2 protease family protein
MMP_RS08200		-0.4	-3.0	archaeosine synthase subunit alpha
MMP_RS03385		-0.4	-0.6	cation diffusion facilitator family transporter
MMP_RS01805		-0.4	-2.2	NUDIX hydrolase
MMP_RS01325		-0.4	-1.0	dihydroneopterin aldolase family protein
MMP_RS00155		-0.4	-2.1	heavy metal-binding domain-containing protein
MMP_RS04870		-0.4	-2.2	TIGR02253 family HAD-type hydrolase
MMP_RS04685		-0.4	-1.3	DUF126 domain-containing protein
MMP_RS00910		-0.4	-2.1	2-phosphosulfolactate phosphatase
MMP_RS01495		-0.4	-2.0	TraB/GumN family protein
MMP_RS01725		-0.4	-1.4	class I SAM-dependent methyltransferase family protein
MMP_RS01115		-0.4	-2.7	molybdopterin molybdotransferase MoeA
MMP_RS08990		-0.4	-2.6	hypothetical protein
MMP_RS01785		-0.4	-1.9	hypothetical protein
MMP_RS08445		-0.4	-1.8	DUF2099 family protein
MMP_RS01925		-0.4	-2.0	DUF1616 domain-containing protein
MMP_RS06485		-0.4	-0.5	zinc ribbon domain-containing protein
MMP_RS03490		-0.4	-0.9	DUF2115 domain-containing protein
MMP_RS07955		-0.4	-1.9	FumA C-terminus/TtdB family hydratase beta subunit
MMP_RS06610		-0.4	-1.7	DUF2334 domain-containing protein
MMP_RS00695		-0.4	-0.4	biotin--[acetyl-CoA-carboxylase] ligase
MMP_RS06860		-0.4	-1.0	4Fe-4S binding protein
MMP_RS02965		-0.4	-1.6	carboxymuconolactone decarboxylase family protein
MMP_RS00705		-0.3	-1.2	hypothetical protein
MMP_RS00295		-0.3	-1.0	gamma carbonic anhydrase family protein
MMP_RS07710		-0.3	-1.9	cell division protein FtsZ
MMP_RS03550		-0.3	-0.9	DUF2124 domain-containing protein
MMP_RS07385		-0.3	-0.6	protein translocase SEC61 complex subunit gamma
MMP_RS06130		-0.3	-1.2	peptidylprolyl isomerase
MMP_RS04875		-0.3	-1.5	energy-converting hydrogenase B subunit P
MMP_RS06190		-0.3	-2.5	tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO
MMP_RS04585		-0.3	-2.2	AIR synthase related protein
MMP_RS01460		-0.3	-0.8	hypothetical protein
MMP_RS05835		-0.3	-0.4	secondary thiamine-phosphate synthase enzyme YjbQ
MMP_RS01095		-0.3	-2.1	iron ABC transporter permease
MMP_RS08770		-0.3	-2.1	hypothetical protein
MMP_RS00110		-0.3	-1.1	hypothetical protein
MMP_RS06055		-0.3	-1.8	peroxiredoxin
MMP_RS02170		-0.3	-1.2	CBS domain-containing protein
MMP_RS03620		-0.3	-2.5	hypothetical protein
MMP_RS06585		-0.3	-0.8	DMT family protein
MMP_RS08585		-0.3	-1.7	flagellin
MMP_RS05525		-0.3	-1.8	calcium/sodium antiporter
MMP_RS01275		-0.3	-1.9	class III signal peptide-containing protein
MMP_RS01005		-0.3	-0.6	riboflavin synthase
MMP_RS05555		-0.3	-0.6	DUF4040 domain-containing protein
MMP_RS05290		-0.3	-1.8	TetR/AcrR family transcriptional regulator
MMP_RS05815		-0.3	-0.6	NOL1/NOP2/sun family putative RNA methylase
MMP_RS00965		-0.3	-1.3	hypothetical protein
MMP_RS04780		-0.3	-0.9	ribonuclease P
MMP_RS04185		-0.3	-2.2	aldo/keto reductase
MMP_RS05505		-0.3	-1.9	class IV adenylate cyclase
MMP_RS02190		-0.3	-0.8	sulfopyruvate decarboxylase subunit alpha
MMP_RS01980		-0.3	-2.1	trimeric intracellular cation channel family protein
MMP_RS00770		-0.3	-1.3	hypothetical protein
MMP_RS08665		-0.3	-2.3	hypothetical protein
MMP_RS06350		-0.3	-1.6	HesA/MoeB/ThiF family protein
MMP_RS05295		-0.3	-2.1	minichromosome maintenance protein MCM
MMP_RS04500		-0.3	-2.2	adenosylmethionine--8-amino-7-oxononanoate transaminase
MMP_RS07915		-0.3	-1.7	DUF4870 domain-containing protein
MMP_RS02745		-0.3	-1.0	hypothetical protein
MMP_RS02425		-0.3	-1.7	hypothetical protein
MMP_RS08380		-0.3	-1.7	phosphatase PAP2 family protein
MMP_RS07090		-0.3	-1.8	tRNA (adenine-N1)-methyltransferase
MMP_RS05545		-0.3	-0.9	pyridoxal phosphate-dependent aminotransferase
MMP_RS07560		-0.3	-1.0	prefoldin subunit alpha
MMP_RS08840		-0.3	-1.9	class I SAM-dependent methyltransferase
MMP_RS06430		-0.3	-1.5	6-carboxytetrahydropterin synthase QueD
MMP_RS04135		-0.3	-2.2	DUF3737 family protein
MMP_RS02175		-0.3	-0.3	DUF1611 domain-containing protein
MMP_RS00665		-0.3	-1.3	hypothetical protein
MMP_RS00905		-0.3	-1.4	phenylacetate--CoA ligase
MMP_RS04360		-0.3	-1.0	hypothetical protein
MMP_RS02405		-0.3	-1.1	hypothetical protein
MMP_RS04305		-0.3	-1.0	hypothetical protein
MMP_RS02875		-0.3	-1.7	chorismate pyruvate-lyase family protein
MMP_RS01685		-0.3	-1.0	indolepyruvate oxidoreductase subunit beta
MMP_RS06680		-0.3	-2.0	Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain
MMP_RS01905		-0.3	-1.7	glycosyltransferase
MMP_RS04955		-0.3	-1.0	DNA topoisomerase I
MMP_RS08485		-0.3	-1.7	tungstate ABC transporter substrate-binding protein WtpA
MMP_RS07685		-0.3	-1.6	TIGR01212 family radical SAM protein
MMP_RS03895		-0.3	-1.0	hypothetical protein
MMP_RS00825		-0.3	-0.7	fumarylacetoacetate hydrolase family protein
MMP_RS02020		-0.3	-1.2	gamma-glutamylcyclotransferase
MMP_RS03870		-0.3	-1.3	purine NTPase
MMP_RS00625		-0.3	-1.1	hypothetical protein
MMP_RS02230		-0.3	-1.3	sodium-dependent transporter
MMP_RS00040		-0.3	-1.1	TIGR03576 family pyridoxal phosphate-dependent enzyme
MMP_RS05315		-0.3	-0.7	hypothetical protein
MMP_RS04165		-0.2	-1.1	TetR/AcrR family transcriptional regulator
MMP_RS00400		-0.2	-1.5	tributyrin esterase
MMP_RS04100		-0.2	-0.9	hypothetical protein
MMP_RS03065		-0.2	-0.8	AzlC family ABC transporter permease
MMP_RS08265		-0.2	-1.3	rubrerythrin
MMP_RS07820		-0.2	-1.1	UPF0104 family protein
MMP_RS03080		-0.2	-0.6	universal stress protein
MMP_RS01650		-0.2	-0.4	sulfurtransferase TusA family protein
MMP_RS07125		-0.2	-1.3	coenzyme F420-reducing hydrogenase FrhD protein
MMP_RS07200		-0.2	-1.2	[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
MMP_RS02785		-0.2	-1.2	MarR family transcriptional regulator
MMP_RS01085		-0.2	-0.6	hypothetical protein
MMP_RS01780		-0.2	-1.6	TrmJ/YjtD family RNA methyltransferase
MMP_RS07545		-0.2	-0.4	HTH domain-containing protein
MMP_RS06710		-0.2	-1.1	selenium-binding protein
MMP_RS04090		-0.2	-0.5	hypothetical protein
MMP_RS02960		-0.2	-1.4	class I SAM-dependent methyltransferase family protein
MMP_RS02940		-0.2	-1.5	TatD family hydrolase
MMP_RS05110		-0.2	-1.2	16S ribosomal RNA methyltransferase A
MMP_RS01330		-0.2	-1.8	DHH family phosphoesterase
MMP_RS08410		-0.2	-0.8	DUF169 domain-containing protein
MMP_RS01490		-0.2	-1.3	tetratricopeptide repeat protein
MMP_RS05500		-0.2	-1.3	2-isopropylmalate synthase
MMP_RS06570		-0.2	-0.6	DUF190 domain-containing protein
MMP_RS05925		-0.2	-0.8	small nuclear ribonucleoprotein
MMP_RS00090		-0.2	-1.0	CoA-binding protein

Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments

For stress EDTA across organisms