Experiment set5IT054 for Klebsiella michiganensis M5al

Compare to:

D,L-Malic Acid carbon source

200 most important genes:

  gene name fitness t score description  
BWI76_RS18955 -8.3 -5.8 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS21475 -8.2 -5.7 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS18950 -7.9 -5.4 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS00850 -7.8 -10.7 acetylglutamate kinase compare
BWI76_RS18930 -7.3 -4.0 histidinol-phosphate transaminase compare
BWI76_RS08520 -7.3 -4.8 colicin transporter TolQ compare
BWI76_RS04250 -7.2 -7.0 homoserine kinase compare
BWI76_RS05840 -7.1 -4.9 glutamate 5-kinase compare
BWI76_RS20965 -7.1 -5.7 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS18935 -7.0 -8.3 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS01615 -6.9 -8.2 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS11965 -6.8 -5.6 orotidine-5'-phosphate decarboxylase compare
BWI76_RS00855 -6.8 -6.6 argininosuccinate lyase compare
BWI76_RS00845 -6.7 -8.0 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS20350 -6.7 -7.9 amidophosphoribosyltransferase compare
BWI76_RS04245 -6.5 -12.6 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS00980 -6.4 -9.8 PLP-dependent threonine dehydratase compare
BWI76_RS05835 -6.4 -4.4 gamma-glutamyl-phosphate reductase compare
BWI76_RS23220 -6.3 -8.6 amino-acid N-acetyltransferase compare
BWI76_RS04645 -6.2 -7.4 3-dehydroquinase compare
BWI76_RS04670 -6.0 -10.0 3-isopropylmalate dehydratase large subunit compare
BWI76_RS04470 -6.0 -10.7 carbamoyl phosphate synthase large subunit compare
BWI76_RS04680 -6.0 -12.0 2-isopropylmalate synthase compare
BWI76_RS23360 -6.0 -4.1 diaminopimelate decarboxylase compare
BWI76_RS04685 -5.9 -11.3 putative leucine operon leader peptide compare
BWI76_RS00805 -5.9 -6.1 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS04665 -5.9 -21.1 3-isopropylmalate dehydratase small subunit compare
BWI76_RS09755 -5.9 -9.8 phosphoserine transaminase compare
BWI76_RS01325 -5.8 -3.8 twin-arginine translocase subunit TatB compare
BWI76_RS01655 -5.7 -8.9 homoserine O-succinyltransferase compare
BWI76_RS04255 -5.7 -9.6 threonine synthase compare
BWI76_RS07070 -5.7 -5.5 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS20355 -5.7 -3.3 colicin V production protein compare
BWI76_RS10990 -5.7 -3.3 dihydroorotase compare
BWI76_RS04160 -5.7 -6.7 phosphoserine phosphatase compare
BWI76_RS18940 -5.7 -6.5 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS18925 -5.6 -8.6 histidinol dehydrogenase compare
BWI76_RS26085 -5.6 -3.8 3-dehydroquinate synthase compare
BWI76_RS18920 -5.6 -4.8 ATP phosphoribosyltransferase compare
BWI76_RS23920 -5.5 -5.9 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS25320 -5.5 -9.4 glutamate synthase compare
BWI76_RS20895 -5.4 -7.4 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS08535 -5.4 -3.5 translocation protein TolB compare
BWI76_RS04465 -5.4 -6.4 carbamoyl-phosphate synthase small subunit compare
BWI76_RS02995 -5.4 -9.6 aspartate carbamoyltransferase compare
BWI76_RS21265 -5.3 -15.1 phosphoribosylformylglycinamidine synthase compare
BWI76_RS22805 -5.3 -11.8 GTP diphosphokinase compare
BWI76_RS05120 -5.3 -12.2 bifunctional glycosyl transferase/transpeptidase compare
BWI76_RS27475 -5.2 -12.2 regulatory protein GntR family protein compare
BWI76_RS04675 -5.2 -8.0 3-isopropylmalate dehydrogenase compare
BWI76_RS09645 -5.1 -2.0 thioredoxin-disulfide reductase compare
BWI76_RS25115 -5.1 -8.1 argininosuccinate synthase compare
BWI76_RS02815 -5.1 -4.4 fructose-bisphosphatase class I compare
BWI76_RS11840 -5.1 -4.0 tryptophan synthase subunit alpha compare
BWI76_RS11850 -5.1 -9.8 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS11855 -4.9 -6.3 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS09910 -4.9 -17.6 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS22755 -4.8 -4.8 phosphoadenosine phosphosulfate reductase compare
BWI76_RS00785 -4.8 -6.6 cystathionine gamma-synthase compare
BWI76_RS11860 -4.8 -8.4 anthranilate synthase component I compare
BWI76_RS10680 -4.7 -4.4 tartrate dehydrogenase compare
BWI76_RS25315 -4.7 -9.4 glutamate synthase large subunit compare
BWI76_RS21140 -4.7 -4.5 molecular chaperone HscA compare
BWI76_RS26455 -4.6 -2.9 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
BWI76_RS23265 -4.6 -4.2 hypothetical protein compare
BWI76_RS24285 -4.5 -8.1 cystathionine beta-lyase compare
BWI76_RS00390 -4.5 -8.6 two-component system sensor histidine kinase NtrB compare
BWI76_RS16250 -4.5 -9.3 DNA-binding response regulator compare
BWI76_RS22760 -4.5 -9.9 sulfite reductase subunit beta compare
BWI76_RS09760 -4.4 -4.6 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS03010 -4.4 -8.2 ornithine carbamoyltransferase compare
BWI76_RS05200 -4.3 -3.0 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS21070 -4.3 -3.4 outer membrane protein assembly factor BamB compare
BWI76_RS25335 -4.3 -5.2 stringent starvation protein A compare
BWI76_RS04510 -4.3 -3.6 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) compare
BWI76_RS23365 -4.3 -5.3 LysR family transcriptional regulator compare
BWI76_RS22765 -4.3 -15.7 sulfite reductase subunit alpha compare
BWI76_RS00385 -4.3 -10.8 nitrogen assimilation regulatory protein compare
BWI76_RS26460 -4.2 -5.3 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS11275 -4.2 -8.5 sensor protein PhoQ compare
BWI76_RS08395 -4.2 -2.8 succinate dehydrogenase cytochrome b556 large subunit compare
BWI76_RS08530 -4.2 -3.3 protein TolA compare
BWI76_RS00990 -4.2 -8.2 ketol-acid reductoisomerase compare
BWI76_RS08385 -4.1 -5.7 citrate (Si)-synthase compare
BWI76_RS22690 -4.1 -4.9 adenylyl-sulfate kinase compare
BWI76_RS25475 -4.1 -13.4 TIGR02099 family protein compare
BWI76_RS16260 -4.1 -2.8 two-component sensor histidine kinase compare
BWI76_RS09660 -4.0 -2.8 DNA translocase FtsK compare
BWI76_RS16965 -4.0 -2.8 murein lipoprotein compare
BWI76_RS11845 -4.0 -3.1 tryptophan synthase subunit beta compare
BWI76_RS00975 -4.0 -5.5 dihydroxy-acid dehydratase compare
BWI76_RS21465 -4.0 -4.4 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS27385 -3.9 -6.1 orotate phosphoribosyltransferase compare
BWI76_RS20435 -3.9 -2.2 chorismate synthase compare
BWI76_RS10685 -3.8 -7.0 LysR family transcriptional regulator compare
BWI76_RS20150 -3.8 -3.7 NADH:ubiquinone oxidoreductase subunit J compare
BWI76_RS05015 -3.7 -3.7 transcriptional regulator compare
BWI76_RS01610 -3.7 -6.9 phosphoribosylamine--glycine ligase compare
BWI76_RS22700 -3.7 -7.0 sulfate adenylyltransferase subunit 2 compare
BWI76_RS20145 -3.6 -2.5 NADH-quinone oxidoreductase subunit K compare
BWI76_RS08525 -3.6 -5.2 colicin transporter compare
BWI76_RS00400 -3.6 -2.2 glutamine synthetase compare
BWI76_RS03080 -3.6 -4.5 (Fe-S)-cluster assembly protein compare
BWI76_RS01210 -3.5 -4.9 tyrosine recombinase XerC compare
BWI76_RS07065 -3.4 -9.0 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS27390 -3.4 -3.9 ribonuclease PH compare
BWI76_RS15975 -3.4 -1.9 hypothetical protein compare
BWI76_RS04705 -3.4 -5.3 DNA-binding transcriptional regulator FruR compare
BWI76_RS01185 -3.3 -2.3 adenylate cyclase compare
BWI76_RS00140 -3.3 -1.8 phosphate transport system regulator PhoU compare
BWI76_RS20640 -3.2 -5.3 cysteine synthase A compare
BWI76_RS19905 -3.2 -6.2 OmpK36 porin compare
BWI76_RS19685 -3.2 -6.5 lysine transporter compare
BWI76_RS22695 -3.1 -6.9 sulfate adenylyltransferase compare
BWI76_RS23240 -3.1 -4.2 exonuclease V subunit gamma compare
BWI76_RS20140 -3.1 -7.5 NADH-quinone oxidoreductase subunit L compare
BWI76_RS03415 -3.1 -5.1 LacI family transcriptional regulator compare
BWI76_RS04240 -3.1 -1.8 thr operon leader peptide compare
BWI76_RS09030 -3.0 -5.8 transpeptidase compare
BWI76_RS20190 -3.0 -9.2 NADH-quinone oxidoreductase subunit A compare
BWI76_RS26670 -3.0 -8.7 two-component sensor histidine kinase compare
BWI76_RS23230 -3.0 -3.5 exodeoxyribonuclease V subunit beta compare
BWI76_RS17720 -2.9 -2.3 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS09640 -2.9 -5.2 cysteine/glutathione ABC transporter permease/ATP-binding protein CydD compare
BWI76_RS03225 -2.9 -9.5 transcriptional regulator compare
BWI76_RS05180 -2.8 -5.4 serine endoprotease DegQ compare
BWI76_RS00985 -2.8 -7.9 transcriptional regulator IlvY compare
BWI76_RS26665 -2.7 -3.3 DNA-binding response regulator compare
BWI76_RS19555 -2.7 -5.3 Beta-glucoside phosphotransferase system, IIA/IIB/IIC components (from data) compare
BWI76_RS27235 -2.6 -8.1 murein hydrolase activator EnvC compare
BWI76_RS16425 -2.6 -3.1 hypothetical protein compare
BWI76_RS06535 -2.6 -6.5 endopeptidase La compare
BWI76_RS25425 -2.5 -2.3 arginine repressor compare
BWI76_RS08405 -2.5 -2.9 succinate dehydrogenase flavoprotein subunit compare
BWI76_RS20130 -2.5 -8.0 NADH-quinone oxidoreductase subunit N compare
BWI76_RS05450 -2.5 -2.3 ribonuclease HI compare
BWI76_RS06525 -2.5 -5.8 ATP-dependent Clp protease proteolytic subunit compare
BWI76_RS06495 -2.5 -8.5 cytochrome ubiquinol oxidase subunit II compare
BWI76_RS20170 -2.5 -5.2 NADH-quinone oxidoreductase subunit F compare
BWI76_RS02410 -2.5 -2.3 EF-P beta-lysylation protein EpmB compare
BWI76_RS20155 -2.4 -3.2 NADH-quinone oxidoreductase subunit I compare
BWI76_RS27450 -2.4 -5.9 ferredoxin--NADP(+) reductase compare
BWI76_RS26390 -2.4 -5.4 cell division protein FtsX compare
BWI76_RS26940 -2.4 -8.7 transcriptional regulator compare
BWI76_RS20650 -2.4 -3.1 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS25420 -2.3 -6.2 malate dehydrogenase compare
BWI76_RS25415 -2.3 -4.7 GntR family transcriptional regulator compare
BWI76_RS09635 -2.3 -4.0 amino acid ABC transporter ATP-binding protein compare
BWI76_RS00965 -2.3 -1.7 acetolactate synthase 2 small subunit compare
BWI76_RS20135 -2.3 -5.4 NADH-quinone oxidoreductase subunit M compare
BWI76_RS01070 -2.3 -8.5 thiol reductase thioredoxin compare
BWI76_RS05260 -2.2 -2.2 chaperone compare
BWI76_RS20695 -2.2 -4.9 sulfate/thiosulfate transporter permease subunit compare
BWI76_RS01330 -2.1 -4.4 twin-arginine translocase subunit TatC compare
BWI76_RS07995 -2.1 -4.0 twin-arginine translocase subunit TatA compare
BWI76_RS23420 -2.1 -10.7 LacI family transcriptional regulator compare
BWI76_RS26395 -2.1 -5.4 cell division protein FtsE compare
BWI76_RS09970 -2.1 -3.2 porin OmpA compare
BWI76_RS20165 -2.0 -7.0 NADH-quinone oxidoreductase subunit G compare
BWI76_RS27075 -2.0 -6.2 IclR family transcriptional regulator compare
BWI76_RS20995 -2.0 -5.2 RNA degradosome polyphosphate kinase compare
BWI76_RS05680 -2.0 -5.1 LacI family transcriptional regulator compare
BWI76_RS19705 -2.0 -4.3 kinase compare
BWI76_RS19840 -2.0 -1.8 hypothetical protein compare
BWI76_RS25410 -2.0 -8.3 GntR family transcriptional regulator with compare
BWI76_RS27305 -2.0 -6.4 glycosyl transferase compare
BWI76_RS25280 -2.0 -2.4 RNase adaptor protein RapZ compare
BWI76_RS03880 -1.9 -5.2 homoprotocatechuate degradation operon regulator, HpaR compare
BWI76_RS27860 -1.9 -5.9 D-serine dehydratase compare
BWI76_RS06605 -1.9 -5.2 ammonium transporter compare
BWI76_RS07435 -1.9 -6.4 LacI family transcriptional regulator compare
BWI76_RS06475 -1.9 -1.7 protoheme IX farnesyltransferase compare
BWI76_RS23340 -1.9 -2.1 transcriptional regulator compare
BWI76_RS21450 -1.8 -3.2 23S rRNA pseudouridine(1911/1915/1917) synthase compare
BWI76_RS06185 -1.8 -9.1 shikimate kinase II compare
BWI76_RS02580 -1.7 -1.7 23S rRNA (guanosine(2251)-2'-O)-methyltransferase compare
BWI76_RS15825 -1.7 -1.5 hypothetical protein compare
BWI76_RS00180 -1.7 -2.2 F0F1 ATP synthase subunit epsilon compare
BWI76_RS27310 -1.7 -6.5 glycosyltransferase compare
BWI76_RS21350 -1.7 -2.8 anti-RNA polymerase sigma factor SigE compare
BWI76_RS23830 -1.7 -8.2 hypothetical protein compare
BWI76_RS21075 -1.7 -2.3 membrane protein compare
BWI76_RS24025 -1.6 -7.4 agmatinase compare
BWI76_RS05005 -1.6 -3.0 polynucleotide adenylyltransferase compare
BWI76_RS06485 -1.6 -2.9 cytochrome o ubiquinol oxidase subunit III compare
BWI76_RS19010 -1.6 -3.5 polysaccharide pyruvyl transferase yvff compare
BWI76_RS25975 -1.6 -5.9 phosphoribulokinase compare
BWI76_RS08210 -1.5 -2.1 N-acetylglucosamine-6-phosphate deacetylase compare
BWI76_RS20700 -1.5 -7.2 sulfate/thiosulfate transporter subunit compare
BWI76_RS02735 -1.5 -3.4 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS20180 -1.5 -4.2 NADH-quinone oxidoreductase subunit C/D compare
BWI76_RS15955 -1.5 -10.0 transcriptional regulator compare
BWI76_RS26055 -1.5 -6.3 siroheme synthase compare
BWI76_RS25070 -1.5 -1.6 hypothetical protein compare
BWI76_RS02610 -1.5 -3.9 transcriptional regulator compare
BWI76_RS08110 -1.5 -2.9 glutamate/aspartate ABC transporter substrate-binding protein compare
BWI76_RS20160 -1.5 -2.8 NADH-quinone oxidoreductase subunit H compare
BWI76_RS15990 -1.5 -4.1 serine protease compare
BWI76_RS01680 -1.4 -4.8 transcriptional regulator IclR compare
BWI76_RS01350 -1.4 -1.1 NAD(P)H-flavin reductase compare


Specific Phenotypes

For 23 genes in this experiment

For carbon source D,L-Malic Acid in Klebsiella michiganensis M5al

For carbon source D,L-Malic Acid across organisms