Experiment set5IT054 for Klebsiella michiganensis M5al

Compare to:

D,L-Malic Acid carbon source

200 most detrimental genes:

  gene name fitness t score description  
BWI76_RS26175 +4.4 30.4 DeoR/GlpR family transcriptional regulator compare
BWI76_RS22240 +2.6 20.3 transcriptional regulator compare
BWI76_RS01800 +2.4 11.4 glucose-6-phosphate isomerase compare
BWI76_RS26180 +2.4 4.1 rhomboid family intramembrane serine protease GlpG compare
BWI76_RS01125 +2.3 11.3 4-alpha-L-fucosyltransferase compare
BWI76_RS25300 +2.1 8.4 hybrid sensor histidine kinase/response regulator compare
BWI76_RS01135 +2.0 9.9 lipopolysaccharide N-acetylmannosaminouronosyltransferase compare
BWI76_RS21165 +1.9 6.0 Fe-S cluster assembly transcriptional regulator IscR compare
BWI76_RS01105 +1.9 7.1 glucose-1-phosphate thymidylyltransferase compare
BWI76_RS01115 +1.9 9.3 dTDP-4-amino-4,6-dideoxygalactose transaminase compare
BWI76_RS01090 +1.9 6.8 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
BWI76_RS00295 +1.8 10.8 transcriptional regulator RbsR compare
BWI76_RS19935 +1.6 3.6 hypothetical protein compare
BWI76_RS16205 +1.6 10.2 NAD(P) transhydrogenase subunit alpha compare
BWI76_RS01095 +1.5 6.0 UDP-N-acetyl-D-mannosamine dehydrogenase compare
BWI76_RS05425 +1.5 10.1 EEP domain-containing protein compare
BWI76_RS16055 +1.5 5.6 malonate decarboxylase subunit epsilon compare
BWI76_RS01080 +1.5 8.9 undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase compare
BWI76_RS16200 +1.4 6.1 NAD(P) transhydrogenase subunit beta compare
BWI76_RS24400 +1.4 9.1 outer membrane channel protein TolC compare
BWI76_RS21250 +1.4 7.4 two-component system response regulator GlrR compare
BWI76_RS20230 +1.3 2.2 hypothetical protein compare
BWI76_RS09725 +1.3 5.2 MurR/RpiR family transcriptional regulator compare
BWI76_RS01585 +1.3 8.2 transcriptional regulator compare
BWI76_RS26575 +1.3 5.6 universal stress protein B compare
BWI76_RS05350 +1.3 7.7 Rcs stress response system protein RcsF compare
BWI76_RS00290 +1.3 6.8 Ribokinase (EC 2.7.1.15) (from data) compare
BWI76_RS03105 +1.3 2.0 myo-inosose-2 dehydratase compare
BWI76_RS06540 +1.2 4.3 DNA-binding protein HU-beta compare
BWI76_RS22815 +1.2 8.0 hybrid sensor histidine kinase/response regulator compare
BWI76_RS15015 +1.2 2.1 DUF2132 domain-containing protein compare
BWI76_RS06150 +1.2 9.3 transcriptional regulator compare
BWI76_RS24385 +1.2 8.7 phosphodiesterase compare
BWI76_RS16050 +1.2 3.4 malonate decarboxylase holo-ACP synthase compare
BWI76_RS24575 +1.2 1.6 hypothetical protein compare
BWI76_RS19910 +1.1 7.2 phosphotransferase RcsD compare
BWI76_RS16485 +1.1 2.3 ribonuclease T compare
BWI76_RS03045 +1.1 1.8 hypothetical protein compare
BWI76_RS19920 +1.1 7.2 hybrid sensor histidine kinase/response regulator compare
BWI76_RS01110 +1.1 3.1 TDP-fucosamine acetyltransferase compare
BWI76_RS26765 +1.1 6.3 phosphodiesterase compare
BWI76_RS14670 +1.1 3.4 hypothetical protein compare
BWI76_RS01995 +1.1 1.6 AraC family transcriptional regulator compare
BWI76_RS21255 +1.1 6.5 hypothetical protein compare
BWI76_RS08645 +1.1 2.5 molybdate ABC transporter substrate-binding protein compare
BWI76_RS13195 +1.1 2.7 glutamate dehydrogenase compare
BWI76_RS16935 +1.1 1.6 shikimate dehydrogenase compare
BWI76_RS11435 +1.0 2.2 hypothetical protein compare
BWI76_RS13970 +1.0 2.2 ABC transporter compare
BWI76_RS16470 +1.0 2.0 transcriptional repressor NemR compare
BWI76_RS16715 +1.0 7.1 hypothetical protein compare
BWI76_RS01100 +1.0 2.9 dTDP-glucose 4,6-dehydratase compare
BWI76_RS15215 +1.0 1.3 N-acetyltransferase compare
BWI76_RS03285 +1.0 2.1 hypothetical protein compare
BWI76_RS21245 +1.0 3.1 nitrogen regulatory protein P-II compare
BWI76_RS15960 +1.0 3.0 LysR family transcriptional regulator compare
BWI76_RS20530 +1.0 4.7 hypothetical protein compare
BWI76_RS24810 +0.9 2.9 hypothetical protein compare
BWI76_RS17045 +0.9 1.5 hypothetical protein compare
BWI76_RS13215 +0.9 1.8 type I glyceraldehyde-3-phosphate dehydrogenase compare
BWI76_RS01560 +0.9 3.2 Rsd/AlgQ family anti-sigma factor compare
BWI76_RS12040 +0.9 1.5 hypothetical protein compare
BWI76_RS24920 +0.9 2.1 YraN family protein compare
BWI76_RS24965 +0.9 2.0 SCP2 domain-containing protein compare
BWI76_RS20900 +0.9 1.7 outer membrane protein assembly factor BamC compare
BWI76_RS11520 +0.9 1.3 hypothetical protein compare
BWI76_RS21260 +0.9 4.8 two-component sensor histidine kinase compare
BWI76_RS19750 +0.9 2.6 elongation factor P-like protein YeiP compare
BWI76_RS06805 +0.9 1.7 primosomal replication protein N'' compare
BWI76_RS18335 +0.9 5.8 DNA-binding response regulator compare
BWI76_RS12470 +0.9 1.7 thiosulfate sulfurtransferase PspE compare
BWI76_RS25545 +0.9 2.7 hypothetical protein compare
BWI76_RS04305 +0.9 0.8 molecular chaperone DnaJ compare
BWI76_RS23305 +0.9 1.6 NADP(H)-dependent aldo-keto reductase compare
BWI76_RS09240 +0.9 3.4 phosphoadenosine phosphosulfate reductase compare
BWI76_RS11810 +0.8 2.6 outer membrane protein OmpW compare
BWI76_RS15135 +0.8 3.4 hypothetical protein compare
BWI76_RS07640 +0.8 1.8 short chain dehydrogenase compare
BWI76_RS19835 +0.8 3.7 nucleoid-associated protein YejK compare
BWI76_RS15195 +0.8 2.2 DUF4186 domain-containing protein compare
BWI76_RS24380 +0.8 3.5 esterase YqiA compare
BWI76_RS08735 +0.8 3.4 Urocanate hydratase (EC 4.2.1.49) (from data) compare
BWI76_RS24490 +0.8 4.5 glycerol-3-phosphate acyltransferase compare
BWI76_RS01120 +0.8 2.7 O-antigen translocase compare
BWI76_RS18360 +0.8 2.3 aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase family protein compare
BWI76_RS14980 +0.8 1.9 hypothetical protein compare
BWI76_RS09085 +0.8 3.2 molybdopterin molybdenumtransferase MoeA compare
BWI76_RS22645 +0.8 4.0 RNA polymerase sigma factor RpoS compare
BWI76_RS20310 +0.8 2.0 hypothetical protein compare
BWI76_RS08655 +0.8 2.0 molybdenum ABC transporter ATP-binding protein compare
BWI76_RS21710 +0.8 3.9 nitroreductase compare
BWI76_RS13330 +0.8 1.5 tellurite resistance methyltransferase TehB compare
BWI76_RS13250 +0.8 1.1 cytochrome b561 compare
BWI76_RS01260 +0.8 3.7 lysophospholipase L2 compare
BWI76_RS17805 +0.8 1.2 membrane protein compare
BWI76_RS15290 +0.8 1.3 transcriptional regulator compare
BWI76_RS12485 +0.8 3.1 TyrR family transcriptional regulator compare
BWI76_RS24610 +0.7 3.0 dihydroxyacetone kinase compare
BWI76_RS16195 +0.7 1.3 hypothetical protein compare
BWI76_RS08585 +0.7 1.4 nicotinamide riboside transporter PnuC compare
BWI76_RS18755 +0.7 1.2 adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase compare
BWI76_RS16190 +0.7 2.1 universal stress protein UspE compare
BWI76_RS17570 +0.7 1.1 iron-sulfur-binding protein compare
BWI76_RS20795 +0.7 1.1 ethanolamine catabolic microcompartment shell protein EutN compare
BWI76_RS23690 +0.7 1.6 putative glyoxalase/bleomycin resistance protein/dioxygenase compare
BWI76_RS06405 +0.7 1.0 2-dehydropantoate 2-reductase compare
BWI76_RS06465 +0.7 1.5 IclR family transcriptional regulator compare
BWI76_RS09870 +0.7 4.6 aromatic amino acid aminotransferase compare
BWI76_RS11410 +0.7 1.5 leucine efflux protein compare
BWI76_RS06205 +0.7 2.8 recombination-associated protein RdgC compare
BWI76_RS18060 +0.7 1.6 hypothetical protein compare
BWI76_RS11675 +0.7 1.4 arginine N-succinyltransferase compare
BWI76_RS20940 +0.7 1.5 uracil/xanthine transporter compare
BWI76_RS18915 +0.7 1.4 NAD(P)-dependent oxidoreductase compare
BWI76_RS08275 +0.7 1.2 LexA regulated protein compare
BWI76_RS14050 +0.7 1.8 AP endonuclease, family 2 compare
BWI76_RS12855 +0.7 1.6 enamine deaminase RidA compare
BWI76_RS02655 +0.7 1.6 hypothetical protein compare
BWI76_RS10910 +0.7 1.8 hypothetical protein compare
BWI76_RS12565 +0.7 3.8 SAM-dependent methyltransferase compare
BWI76_RS14065 +0.7 0.8 hypothetical protein compare
BWI76_RS15150 +0.7 2.8 outer membrane efflux protein compare
BWI76_RS05755 +0.7 4.2 beta-ketoacyl-[acyl-carrier-protein] synthase II compare
BWI76_RS12585 +0.7 2.8 transcriptional regulator compare
BWI76_RS26210 +0.7 3.7 glycogen debranching enzyme compare
BWI76_RS06285 +0.6 2.2 peroxiredoxin compare
BWI76_RS22375 +0.6 2.2 pectin acetylesterase compare
BWI76_RS06745 +0.6 2.1 N-acetyltransferase GCN5 compare
BWI76_RS09080 +0.6 1.4 molybdopterin-synthase adenylyltransferase MoeB compare
BWI76_RS18390 +0.6 1.8 hypothetical protein compare
BWI76_RS22100 +0.6 2.4 multidrug effux MFS transporter subunit EmrB compare
BWI76_RS02255 +0.6 2.8 chaperone-modulator protein CbpM compare
BWI76_RS11635 +0.6 1.0 ABC transporter compare
BWI76_RS16120 +0.6 1.1 4-carboxymuconolactone decarboxylase compare
BWI76_RS00865 +0.6 2.6 DNA-binding transcriptional regulator OxyR compare
BWI76_RS10435 +0.6 2.0 suppressor for copper-sensitivity C compare
BWI76_RS12070 +0.6 0.9 hypothetical protein compare
BWI76_RS11440 +0.6 0.9 hypothetical protein compare
BWI76_RS21285 +0.6 1.4 HAD family hydrolase compare
BWI76_RS00790 +0.6 3.2 bifunctional aspartokinase II/homoserine dehydrogenase II compare
BWI76_RS12790 +0.6 1.1 lactate dehydrogenase compare
BWI76_RS07745 +0.6 3.3 isochorismate synthase EntC compare
BWI76_RS26780 +0.6 3.9 cellulose synthase regulator BcsB compare
BWI76_RS21910 +0.6 2.8 glyoxylate/hydroxypyruvate reductase A compare
BWI76_RS19310 +0.6 1.5 ABC transporter permease compare
BWI76_RS02090 +0.6 2.2 membrane protein compare
BWI76_RS07710 +0.6 1.7 invasin-like protein compare
BWI76_RS20720 +0.6 0.9 hypothetical protein compare
BWI76_RS18140 +0.6 2.1 zinc ABC transporter permease compare
BWI76_RS25285 +0.6 0.7 HPr family phosphocarrier protein compare
BWI76_RS05950 +0.6 1.2 polar amino acid ABC transporter inner membrane subunit compare
BWI76_RS09335 +0.6 0.9 baseplate assembly protein W compare
BWI76_RS16300 +0.6 1.7 bifunctional beta-cystathionase/maltose regulon regulatory protein compare
BWI76_RS09315 +0.6 1.1 hypothetical protein compare
BWI76_RS16915 +0.6 2.5 alpha/beta hydrolase fold protein compare
BWI76_RS06780 +0.6 2.7 MexE family multidrug efflux RND transporter periplasmic adaptor subunit compare
BWI76_RS23245 +0.6 1.1 hypothetical protein compare
BWI76_RS26660 +0.6 2.9 transcription elongation factor GreB compare
BWI76_RS19105 +0.6 3.8 GalU regulator GalF compare
BWI76_RS22465 +0.6 2.4 hemin ABC transporter substrate-binding protein compare
BWI76_RS24770 +0.6 1.4 hypothetical protein compare
BWI76_RS11640 +0.6 1.8 ABC transporter membrane protein compare
BWI76_RS21905 +0.6 2.3 class II aldolase compare
BWI76_RS15190 +0.6 3.7 GGDEF domain-containing protein compare
BWI76_RS02225 +0.6 1.3 phosphonate C-P lyase system protein PhnG compare
BWI76_RS17915 +0.6 2.2 membrane protein compare
BWI76_RS19510 +0.6 3.1 beta-glucosidase compare
BWI76_RS02455 +0.6 3.8 fumarate reductase flavoprotein subunit compare
BWI76_RS21715 +0.6 1.5 transcriptional regulator compare
BWI76_RS08650 +0.6 1.8 molybdate ABC transporter permease compare
BWI76_RS17860 +0.6 1.3 YoaH family protein compare
BWI76_RS06630 +0.6 1.9 hypothetical protein compare
BWI76_RS27520 +0.6 2.1 sodium/glutamate symporter compare
BWI76_RS26285 +0.6 2.3 glycerophosphodiester phosphodiesterase compare
BWI76_RS21460 +0.6 1.1 translation inhibitor protein RaiA compare
BWI76_RS27445 +0.6 2.3 fructose-bisphosphatase class II compare
BWI76_RS05810 +0.6 0.9 hypothetical protein compare
BWI76_RS11895 +0.6 2.1 AraC family transcriptional regulator compare
BWI76_RS10060 +0.6 1.0 acylphosphatase compare
BWI76_RS18175 +0.6 1.9 hydrolase compare
BWI76_RS08820 +0.6 2.5 molybdenum cofactor biosynthesis protein compare
BWI76_RS01380 +0.6 1.7 YigZ family protein compare
BWI76_RS14870 +0.6 1.8 hypothetical protein compare
BWI76_RS17820 +0.6 1.6 hypothetical protein compare
BWI76_RS09330 +0.5 1.5 baseplate assembly protein V compare
BWI76_RS09450 +0.5 0.9 30S ribosomal protein S6--L-glutamate ligase compare
BWI76_RS04895 +0.5 1.7 hypothetical protein compare
BWI76_RS27635 +0.5 1.4 AraC family transcriptional regulator compare
BWI76_RS00475 +0.5 2.7 sulfurtransferase FdhD compare
BWI76_RS07740 +0.5 1.2 Fe2+-enterobactin ABC transporter substrate-binding protein compare
BWI76_RS01335 +0.5 1.4 DNase TatD compare
BWI76_RS06075 +0.5 1.4 taurine transporter subunit compare
BWI76_RS17900 +0.5 2.1 PTS mannose transporter subunit IID compare
BWI76_RS14155 +0.5 1.8 transketolase compare
BWI76_RS06775 +0.5 3.1 multidrug efflux RND transporter permease subunit compare
BWI76_RS27005 +0.5 2.2 hypothetical protein compare
BWI76_RS15985 +0.5 2.2 LysR family transcriptional regulator compare
BWI76_RS09440 +0.5 1.7 hypothetical protein compare
BWI76_RS18595 +0.5 1.6 hypothetical protein compare
BWI76_RS24080 +0.5 1.3 DUF179 domain-containing protein compare


Specific Phenotypes

For 23 genes in this experiment

For carbon source D,L-Malic Acid in Klebsiella michiganensis M5al

For carbon source D,L-Malic Acid across organisms