Experiment set5IT053 for Methanococcus maripaludis S2

200 most important genes:

gene	name	fitness	t score	description
MMP_RS06110		-1.2	-3.1	ATP-dependent protease LonB
MMP_RS05920		-1.2	-0.8	50S ribosomal protein L37e
MMP_RS07765		-1.2	-6.8	sodium:alanine symporter family protein
MMP_RS08460		-1.2	-2.7	proteasome-activating nucleotidase
MMP_RS08745		-1.1	-5.3	CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase
MMP_RS05280		-1.1	-5.2	COG1361 S-layer family protein
MMP_RS08650		-1.0	-2.8	glutamine--fructose-6-phosphate transaminase (isomerizing)
MMP_RS06175		-1.0	-6.1	winged helix-turn-helix transcriptional regulator
MMP_RS05285		-1.0	-4.5	MMPL family transporter
MMP_RS03600		-1.0	-1.6	triose-phosphate isomerase
MMP_RS07380		-1.0	-1.5	transcription elongation factor Spt5
MMP_RS03110		-1.0	-4.2	glycosyltransferase family 2 protein
MMP_RS03435		-0.9	-1.4	ketol-acid reductoisomerase
MMP_RS03300		-0.9	-0.8	TOBE domain-containing protein
MMP_RS01175		-0.9	-3.2	triphosphoribosyl-dephospho-CoA synthase
MMP_RS07545		-0.8	-1.1	HTH domain-containing protein
MMP_RS01500		-0.8	-1.8	CBS domain-containing protein
MMP_RS08820		-0.8	-3.3	hypothetical protein
MMP_RS01795		-0.8	-1.2	methanogenesis marker 6 protein
MMP_RS06840		-0.8	-0.9	DNA-directed RNA polymerase subunit N
MMP_RS00915		-0.7	-4.2	DUF116 domain-containing protein
MMP_RS03340		-0.7	-0.6	ABC transporter ATP-binding protein
MMP_RS02145		-0.7	-3.7	winged helix-turn-helix transcriptional regulator
MMP_RS04955		-0.7	-3.2	DNA topoisomerase I
MMP_RS01225		-0.7	-3.0	DUF5379 domain-containing protein
MMP_RS08940		-0.7	-0.9	MetS family NSS transporter small subunit
MMP_RS02410		-0.7	-1.5	ABC transporter substrate-binding protein
MMP_RS05875		-0.7	-2.3	hydroxyethylthiazole kinase
MMP_RS08300		-0.7	-0.8	metal-sulfur cluster assembly factor
MMP_RS02595		-0.7	-1.0	putative zinc-binding protein
MMP_RS02045		-0.7	-1.2	tRNA-Met
MMP_RS01100		-0.7	-1.3	ABC transporter ATP-binding protein
MMP_RS05535		-0.7	-2.8	hypothetical protein
MMP_RS00685		-0.7	-2.5	2-phospho-L-lactate guanylyltransferase
MMP_RS04775		-0.6	-2.1	adenosylhomocysteinase
MMP_RS06860		-0.6	-1.4	4Fe-4S binding protein
MMP_RS08195		-0.6	-4.0	hypothetical protein
MMP_RS05315		-0.6	-1.5	hypothetical protein
MMP_RS08380		-0.6	-3.5	phosphatase PAP2 family protein
MMP_RS06540		-0.6	-2.0	3-methyl-2-oxobutanoate dehydrogenase subunit VorB
MMP_RS00305		-0.6	-0.9	phosphoribosyl-ATP diphosphatase
MMP_RS00515		-0.6	-0.7	DUF655 domain-containing protein
MMP_RS00320		-0.6	-1.2	class I SAM-dependent methyltransferase
MMP_RS02195		-0.6	-2.3	tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
MMP_RS01005		-0.6	-0.9	riboflavin synthase
MMP_RS00910		-0.6	-3.4	2-phosphosulfolactate phosphatase
MMP_RS04055		-0.6	-1.0	hypothetical protein
MMP_RS01725		-0.6	-1.7	class I SAM-dependent methyltransferase family protein
MMP_RS06355		-0.6	-1.6	molybdenum cofactor biosynthesis protein MoaE
MMP_RS02965		-0.5	-2.2	carboxymuconolactone decarboxylase family protein
MMP_RS07845		-0.5	-1.6	LL-diaminopimelate aminotransferase
MMP_RS07385		-0.5	-1.3	protein translocase SEC61 complex subunit gamma
MMP_RS01240		-0.5	-1.1	7-cyano-7-deazaguanine synthase QueC
MMP_RS00125		-0.5	-0.9	DUF2798 domain-containing protein
MMP_RS06590		-0.5	-1.6	GNAT family N-acetyltransferase
MMP_RS01925		-0.5	-3.0	DUF1616 domain-containing protein
MMP_RS00300		-0.5	-0.4	6 7-dimethyl-8-ribityllumazine synthase
MMP_RS06285		-0.5	-1.3	precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT
MMP_RS04685		-0.5	-1.6	DUF126 domain-containing protein
MMP_RS05515		-0.5	-3.2	cyclic pyranopterin monophosphate synthase MoaC
MMP_RS06130		-0.5	-1.7	peptidylprolyl isomerase
MMP_RS07970		-0.5	-1.8	hypothetical protein
MMP_RS00315		-0.5	-2.2	Nif3-like dinuclear metal center hexameric protein
MMP_RS04945		-0.5	-2.3	hypothetical protein
MMP_RS00395		-0.5	-0.9	MGMT family protein
MMP_RS03490		-0.5	-1.0	DUF2115 domain-containing protein
MMP_RS06865		-0.5	-1.3	HypC/HybG/HupF family hydrogenase formation chaperone
MMP_RS08600		-0.5	-1.3	flagellar protein D
MMP_RS07815		-0.5	-0.7	DUF2120 domain-containing protein
MMP_RS03875		-0.5	-2.2	hypothetical protein
MMP_RS08200		-0.5	-3.9	archaeosine synthase subunit alpha
MMP_RS01720		-0.5	-1.1	replication factor C large subunit
MMP_RS05505		-0.5	-2.6	class IV adenylate cyclase
MMP_RS01365		-0.5	-1.6	archaeal proteasome endopeptidase complex subunit alpha
MMP_RS00110		-0.4	-1.2	hypothetical protein
MMP_RS05890		-0.4	-3.2	ATP-dependent helicase
MMP_RS01030		-0.4	-1.5	MTAP family purine nucleoside phosphorylase
MMP_RS03025		-0.4	-1.8	molybdenum cofactor guanylyltransferase
MMP_RS01830		-0.4	-0.8	tRNA-Val
MMP_RS00430		-0.4	-1.7	hypothetical protein
MMP_RS07640		-0.4	-1.9	mechanosensitive ion channel family protein
MMP_RS07735		-0.4	-0.4	2-ketoisovalerate ferredoxin oxidoreductase subunit alpha
MMP_RS06190		-0.4	-2.7	tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO
MMP_RS00655		-0.4	-1.4	hypothetical protein
MMP_RS02175		-0.4	-0.4	DUF1611 domain-containing protein
MMP_RS07630		-0.4	-0.7	ATP-binding cassette domain-containing protein
MMP_RS05510		-0.4	-2.7	Rrf2 family transcriptional regulator
MMP_RS06290		-0.4	-1.7	DNA repair and recombination protein RadA
MMP_RS02165		-0.4	-2.3	tRNA-dihydrouridine synthase
MMP_RS07600		-0.4	-1.2	Ni-sirohydrochlorin a c-diamide synthase
MMP_RS03390		-0.4	-2.1	malate dehydrogenase
MMP_RS08430		-0.4	-2.0	HAD family hydrolase
MMP_RS07390		-0.4	-1.2	cell division protein FtsZ
MMP_RS01785		-0.4	-1.3	hypothetical protein
MMP_RS02805		-0.4	-0.6	HEPN domain-containing protein
MMP_RS07345		-0.4	-1.8	glycine synthesis protein GlyXL (from data)
MMP_RS01125		-0.4	-2.4	thioredoxin family protein
MMP_RS08590		-0.4	-1.7	flagellin
MMP_RS00990		-0.4	-1.6	hypothetical protein
MMP_RS01250		-0.4	-1.9	tRNA (guanine(26)-N(2))-dimethyltransferase
MMP_RS00905		-0.4	-2.2	phenylacetate--CoA ligase
MMP_RS00665		-0.4	-1.8	hypothetical protein
MMP_RS08750		-0.4	-1.5	hypothetical protein
MMP_RS08995		-0.4	-0.6	hypothetical protein
MMP_RS02605		-0.4	-0.4	MotA/TolQ/ExbB proton channel family protein
MMP_RS06345		-0.4	-2.7	formate dehydrogenase accessory sulfurtransferase FdhD
MMP_RS04780		-0.4	-1.3	ribonuclease P
MMP_RS05845		-0.4	-0.6	tRNA-intron lyase
MMP_RS01790		-0.4	-2.3	restriction endonuclease
MMP_RS01150		-0.3	-1.9	aldo/keto reductase
MMP_RS05110		-0.3	-1.9	16S ribosomal RNA methyltransferase A
MMP_RS01600		-0.3	-0.9	50S ribosomal protein L15e
MMP_RS01495		-0.3	-2.1	TraB/GumN family protein
MMP_RS04870		-0.3	-1.4	TIGR02253 family HAD-type hydrolase
MMP_RS03095		-0.3	-1.6	diphthine synthase
MMP_RS00085		-0.3	-2.3	DNA cytosine methyltransferase
MMP_RS00675		-0.3	-0.4	nitroreductase family protein
MMP_RS08635		-0.3	-0.6	UbiA family prenyltransferase
MMP_RS00345		-0.3	-1.9	DUF2666 domain-containing protein
MMP_RS08980		-0.3	-1.5	hypothetical protein
MMP_RS08080		-0.3	-2.7	YchF/TatD family DNA exonuclease
MMP_RS04290		-0.3	-1.8	4Fe-4S binding protein
MMP_RS01980		-0.3	-2.4	trimeric intracellular cation channel family protein
MMP_RS08840		-0.3	-2.3	class I SAM-dependent methyltransferase
MMP_RS01255		-0.3	-2.0	amino acid ABC transporter ATP-binding protein
MMP_RS04015		-0.3	-1.1	hypothetical protein
MMP_RS01700		-0.3	-0.3	dihydroxy-acid dehydratase
MMP_RS07575		-0.3	-1.0	RNA ligase partner protein
MMP_RS00115		-0.3	-2.4	radical SAM protein
MMP_RS01775		-0.3	-0.7	TIGR00297 family protein
MMP_RS00895		-0.3	-0.8	hypothetical protein
MMP_RS02680		-0.3	-1.6	ABC transporter permease
MMP_RS08915		-0.3	-1.3	2 5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase
MMP_RS08100		-0.3	-1.8	8-amino-7-oxononanoate synthase
MMP_RS05265		-0.3	-0.5	2-isopropylmalate synthase
MMP_RS08990		-0.3	-1.5	hypothetical protein
MMP_RS02470		-0.3	-0.5	helix-turn-helix transcriptional regulator
MMP_RS07840		-0.3	-1.1	ribonuclease III
MMP_RS08440		-0.3	-0.8	cell division protein SepF
MMP_RS08290		-0.3	-1.9	DNA-binding protein Alba
MMP_RS08165		-0.3	-0.7	phosphoglycerate dehydrogenase
MMP_RS08390		-0.3	-1.4	DUF5400 domain-containing protein
MMP_RS07955		-0.3	-1.1	FumA C-terminus/TtdB family hydratase beta subunit
MMP_RS05290		-0.3	-1.8	TetR/AcrR family transcriptional regulator
MMP_RS00555		-0.3	-1.6	MFS transporter
MMP_RS08105		-0.3	-1.3	6-carboxyhexanoate--CoA ligase
MMP_RS03965		-0.3	-0.8	hypothetical protein
MMP_RS05560		-0.3	-1.2	deoxyuridine 5'-triphosphate nucleotidohydrolase
MMP_RS01430		-0.3	-1.5	mechanosensitive ion channel family protein
MMP_RS00950		-0.3	-1.7	site-2 protease family protein
MMP_RS06585		-0.3	-0.6	DMT family protein
MMP_RS00035		-0.3	-2.0	DUF2098 family protein
MMP_RS01190		-0.3	-2.0	cadmium-translocating P-type ATPase
MMP_RS01905		-0.3	-2.1	glycosyltransferase
MMP_RS00380		-0.3	-0.9	P-II family nitrogen regulator
MMP_RS06430		-0.3	-1.8	6-carboxytetrahydropterin synthase QueD
MMP_RS01155		-0.3	-1.4	XRE family transcriptional regulator
MMP_RS06535		-0.3	-1.3	2-oxoacid:acceptor oxidoreductase family protein
MMP_RS07985		-0.3	-2.2	nitroreductase family protein
MMP_RS02630		-0.3	-1.7	rubredoxin
MMP_RS01265		-0.3	-0.6	hypothetical protein
MMP_RS01640		-0.3	-1.9	2-oxoacid:acceptor oxidoreductase subunit alpha
MMP_RS02875		-0.3	-1.7	chorismate pyruvate-lyase family protein
MMP_RS04060		-0.3	-1.3	hypothetical protein
MMP_RS05965		-0.3	-1.3	carboxymuconolactone decarboxylase family protein
MMP_RS03020		-0.3	-1.2	peptidylprolyl isomerase
MMP_RS01900		-0.3	-1.9	hypothetical protein
MMP_RS05865		-0.3	-1.1	hypothetical protein
MMP_RS01020		-0.3	-0.3	3 4-dihydroxy-2-butanone-4-phosphate synthase
MMP_RS02975		-0.3	-1.2	DUF2124 domain-containing protein
MMP_RS08395		-0.3	-1.1	DsrE family protein
MMP_RS01325		-0.3	-0.6	dihydroneopterin aldolase family protein
MMP_RS05780		-0.3	-2.0	multidrug resistance efflux transporter family protein
MMP_RS02425		-0.3	-1.5	hypothetical protein
MMP_RS06545		-0.3	-1.0	ferredoxin family protein
MMP_RS00620		-0.3	-1.5	4Fe-4S binding protein
MMP_RS08585		-0.3	-1.4	flagellin
MMP_RS02230		-0.3	-1.7	sodium-dependent transporter
MMP_RS02540		-0.3	-1.9	DUF2283 domain-containing protein
MMP_RS01045		-0.3	-1.3	diphthamide biosynthesis enzyme Dph2
MMP_RS07750		-0.3	-1.2	DUF357 domain-containing protein
MMP_RS05490		-0.3	-1.4	IMPACT family protein
MMP_RS06335		-0.3	-0.8	HAD family hydrolase
MMP_RS06710		-0.2	-1.1	selenium-binding protein
MMP_RS05685		-0.2	-1.8	winged helix-turn-helix domain-containing protein
MMP_RS02720		-0.2	-0.8	molybdate ABC transporter substrate-binding protein
MMP_RS08665		-0.2	-1.9	hypothetical protein
MMP_RS05455		-0.2	-1.8	DUF167 domain-containing protein
MMP_RS07195		-0.2	-1.5	M20 family metallo-hydrolase
MMP_RS03080		-0.2	-0.9	universal stress protein
MMP_RS02995		-0.2	-1.3	acyl-CoA thioesterase
MMP_RS07090		-0.2	-1.3	tRNA (adenine-N1)-methyltransferase
MMP_RS01655		-0.2	-0.6	DsrE family protein
MMP_RS07700		-0.2	-1.6	DUF1188 domain-containing protein
MMP_RS00770		-0.2	-1.1	hypothetical protein
MMP_RS06440		-0.2	-1.2	CBS domain-containing protein
MMP_RS00560		-0.2	-1.4	cation:proton antiporter
MMP_RS08075		-0.2	-1.4	DUF749 domain-containing protein
MMP_RS07445		-0.2	-1.5	helix-turn-helix domain-containing protein
MMP_RS02440		-0.2	-1.4	hypothetical protein

Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments

For stress EDTA across organisms