Experiment set5IT053 for Methanococcus maripaludis S2

Compare to:

Formate with EDTA 3.9 mM

200 most detrimental genes:

  gene name fitness t score description  
MMP_RS03960 +2.5 3.3 hypothetical protein compare
MMP_RS02800 +2.2 11.4 nucleotidyltransferase domain-containing protein compare
MMP_RS02100 +1.2 4.2 metallophosphoesterase compare
MMP_RS01610 +1.2 4.3 hypothetical protein compare
MMP_RS01545 +1.2 1.5 CBS domain-containing protein compare
MMP_RS01370 +1.1 7.4 acetate--CoA ligase family protein compare
MMP_RS06705 +1.0 4.5 formate/nitrite transporter family protein compare
MMP_RS08720 +1.0 1.7 4Fe-4S binding protein compare
MMP_RS05435 +1.0 7.6 5'/3'-nucleotidase SurE compare
MMP_RS07605 +1.0 3.1 diadenylate cyclase compare
MMP_RS07180 +1.0 4.4 DEAD/DEAH box helicase compare
MMP_RS06925 +1.0 3.2 ribonuclease VapC4 compare
MMP_RS02355 +1.0 3.5 30S ribosomal protein S27ae compare
MMP_RS02345 +1.0 2.9 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS00325 +0.9 1.4 RNA-binding protein compare
MMP_RS03320 +0.9 4.0 metal-dependent transcriptional regulator compare
MMP_RS02790 +0.9 1.5 class III signal peptide-containing protein compare
MMP_RS00130 +0.9 1.3 nickel-responsive transcriptional regulator NikR compare
MMP_RS01650 +0.9 1.4 sulfurtransferase TusA family protein compare
MMP_RS04090 +0.8 1.2 hypothetical protein compare
MMP_RS05250 +0.8 1.3 NFYB/HAP3 family transcription factor subunit compare
MMP_RS05540 +0.7 2.8 hypothetical protein compare
MMP_RS04520 +0.7 2.4 nucleoside deaminase compare
MMP_RS06625 +0.7 1.7 DNA primase compare
MMP_RS08355 +0.7 3.4 Na(+)/H(+) antiporter subunit B compare
MMP_RS00450 +0.7 1.0 4Fe-4S binding protein compare
MMP_RS06000 +0.7 1.5 divalent-cation tolerance protein CutA compare
MMP_RS06720 +0.7 5.0 response regulator transcription factor compare
MMP_RS02010 +0.7 3.3 PHP domain-containing protein compare
MMP_RS03475 +0.7 0.5 hypothetical protein compare
MMP_RS01800 +0.7 2.2 TIGR00303 family protein compare
MMP_RS08785 +0.6 0.9 RNA-protein complex protein Nop10 compare
MMP_RS07540 +0.6 2.5 CBS domain-containing protein compare
MMP_RS03685 +0.6 3.7 Mrp/NBP35 family ATP-binding protein compare
MMP_RS01885 +0.6 3.2 Gfo/Idh/MocA family oxidoreductase compare
MMP_RS08360 +0.6 1.5 hypothetical protein compare
MMP_RS07365 +0.6 4.8 2-phosphoglycerate kinase compare
MMP_RS07075 +0.6 2.4 phosphomannomutase/phosphoglucomutase compare
MMP_RS06975 +0.6 0.9 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS01575 +0.6 3.0 aldolase compare
MMP_RS03400 +0.6 1.5 archease compare
MMP_RS03145 +0.6 3.6 fibrillarin-like rRNA/tRNA 2'-O-methyltransferase compare
MMP_RS07860 +0.6 0.6 hypothetical protein compare
MMP_RS01525 +0.6 1.4 nucleoside-diphosphate kinase compare
MMP_RS06375 +0.5 3.5 ATP-dependent sacrificial sulfur transferase LarE compare
MMP_RS08320 +0.5 3.1 molybdopterin molybdotransferase MoeA compare
MMP_RS03430 +0.5 3.5 bile acid:sodium symporter family protein compare
MMP_RS04020 +0.5 3.4 hypothetical protein compare
MMP_RS06770 +0.5 3.3 DHH family phosphoesterase compare
MMP_RS01220 +0.5 3.4 hypothetical protein compare
MMP_RS07705 +0.5 3.7 transcriptional regulator compare
MMP_RS06715 +0.5 4.1 cache domain-containing protein compare
MMP_RS06730 +0.5 1.2 phosphopantothenate/pantothenate synthetase compare
MMP_RS04985 +0.5 1.0 DUF2180 family protein compare
MMP_RS05085 +0.5 1.6 AAA family ATPase compare
MMP_RS05850 +0.5 1.3 Ldh family oxidoreductase compare
MMP_RS00060 +0.5 1.1 3-dehydroquinate synthase II compare
MMP_RS00335 +0.5 2.2 5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH compare
MMP_RS00740 +0.5 1.3 cyclase family protein compare
MMP_RS00565 +0.5 1.3 CBS domain-containing protein compare
MMP_RS02475 +0.5 0.9 hypothetical protein compare
MMP_RS03440 +0.5 0.8 MoaD/ThiS family protein compare
MMP_RS07555 +0.5 0.5 monovalent cation/H+ antiporter subunit E compare
MMP_RS07925 +0.4 1.3 haloacid dehalogenase compare
MMP_RS06475 +0.4 1.8 FAD-dependent oxidoreductase compare
MMP_RS08365 +0.4 1.6 energy conserving hydrogenase EhbF compare
MMP_RS03205 +0.4 0.7 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS00710 +0.4 1.0 hypothetical protein compare
MMP_RS06530 +0.4 1.8 bifunctional hexulose-6-phosphate synthase/ribonuclease regulator compare
MMP_RS08215 +0.4 1.3 DUF483 domain-containing protein compare
MMP_RS08070 +0.4 2.8 DUF2096 domain-containing protein compare
MMP_RS03800 +0.4 1.0 hypothetical protein compare
MMP_RS04715 +0.4 2.2 CBS domain-containing protein compare
MMP_RS06915 +0.4 1.3 metallophosphoesterase compare
MMP_RS01110 +0.4 2.1 FmdE family protein compare
MMP_RS00985 +0.4 2.3 CDC48 family AAA ATPase compare
MMP_RS00750 +0.4 1.0 fumarate hydratase compare
MMP_RS03775 +0.4 0.9 4Fe-4S dicluster domain-containing protein compare
MMP_RS00050 +0.4 1.9 AarF/UbiB family protein compare
MMP_RS03405 +0.4 1.4 RNA 3'-terminal phosphate cyclase compare
MMP_RS01975 +0.4 2.9 hypothetical protein compare
MMP_RS03335 +0.4 1.7 ABC transporter permease compare
MMP_RS09020 +0.4 0.8 hypothetical protein compare
MMP_RS08275 +0.4 2.9 hypothetical protein compare
MMP_RS06480 +0.4 2.0 ABC transporter substrate-binding protein compare
MMP_RS08345 +0.4 2.4 4Fe-4S binding protein compare
MMP_RS07095 +0.4 0.9 PspC domain-containing protein compare
MMP_RS07835 +0.4 1.5 TldD/PmbA family protein compare
MMP_RS08235 +0.4 1.3 hypothetical protein compare
MMP_RS08340 +0.4 1.2 4Fe-4S binding protein compare
MMP_RS01675 +0.4 0.8 hypothetical protein compare
MMP_RS00810 +0.4 2.0 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS01930 +0.4 2.5 hypothetical protein compare
MMP_RS05580 +0.4 3.1 glycosyltransferase compare
MMP_RS06340 +0.4 2.3 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS05990 +0.4 1.4 DsrE family protein compare
MMP_RS04430 +0.4 1.3 DUF1847 domain-containing protein compare
MMP_RS08370 +0.4 0.3 cation:proton antiporter subunit C compare
MMP_RS04105 +0.4 1.1 MarR family transcriptional regulator compare
MMP_RS06225 +0.4 2.4 DNA double-strand break repair nuclease NurA compare
MMP_RS04145 +0.3 0.8 hypothetical protein compare
MMP_RS07190 +0.3 1.6 chromosome segregation protein SMC compare
MMP_RS06610 +0.3 1.3 DUF2334 domain-containing protein compare
MMP_RS03150 +0.3 2.1 phosphoglycerate mutase compare
MMP_RS05065 +0.3 1.2 CooT family nickel-binding protein compare
MMP_RS05675 +0.3 1.2 phosphate ABC transporter ATP-binding protein PstB compare
MMP_RS06015 +0.3 1.7 flavodoxin family protein compare
MMP_RS05930 +0.3 0.9 3-isopropylmalate dehydratase large subunit compare
MMP_RS02315 +0.3 1.9 RimK family alpha-L-glutamate ligase compare
MMP_RS02255 +0.3 1.8 hypothetical protein compare
MMP_RS07005 +0.3 0.2 4Fe-4S binding protein compare
MMP_RS04610 +0.3 0.8 Dabb family protein compare
MMP_RS01920 +0.3 2.5 glycosyltransferase family 2 protein compare
MMP_RS01945 +0.3 1.8 DUF4350 domain-containing protein compare
MMP_RS06895 +0.3 0.7 selenocysteine-specific translation elongation factor compare
MMP_RS05635 +0.3 2.0 NAD-dependent epimerase/dehydratase family protein compare
MMP_RS08660 +0.3 1.6 DHH family phosphoesterase compare
MMP_RS08335 +0.3 1.2 NADH-quinone oxidoreductase subunit B family protein compare
MMP_RS06370 +0.3 1.2 biotin synthase BioB compare
MMP_RS04485 +0.3 2.4 putative beta-lysine N-acetyltransferase compare
MMP_RS06140 +0.3 0.7 radical SAM protein compare
MMP_RS02885 +0.3 2.6 molybdopterin biosynthesis protein compare
MMP_RS05365 +0.3 1.0 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH compare
MMP_RS09035 +0.3 0.6 hypothetical protein compare
MMP_RS04360 +0.3 0.9 hypothetical protein compare
MMP_RS07355 +0.3 0.4 transcription factor S compare
MMP_RS00100 +0.3 2.2 tRNA pseudouridine(13) synthase TruD compare
MMP_RS06170 +0.3 2.2 ABC transporter ATP-binding protein compare
MMP_RS06165 +0.3 1.7 ABC transporter permease compare
MMP_RS02930 +0.3 0.8 class I SAM-dependent methyltransferase compare
MMP_RS04740 +0.3 0.9 DUF473 domain-containing protein compare
MMP_RS02970 +0.3 2.0 hypothetical protein compare
MMP_RS00250 +0.3 2.3 Flp pilus assembly complex ATPase component TadA compare
MMP_RS07330 +0.3 2.5 membrane protein compare
MMP_RS00635 +0.3 1.0 energy-coupling factor transporter transmembrane protein EcfT compare
MMP_RS08310 +0.3 0.7 TMEM165/GDT1 family protein compare
MMP_RS04720 +0.3 0.8 DedA family protein compare
MMP_RS03465 +0.3 0.4 adenine phosphoribosyltransferase compare
MMP_RS04265 +0.3 0.9 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS01420 +0.3 0.8 hypothetical protein compare
MMP_RS06630 +0.3 0.4 UPF0058 family protein compare
MMP_RS02290 +0.3 1.6 MBL fold metallo-hydrolase compare
MMP_RS01745 +0.3 1.9 AMP phosphorylase compare
MMP_RS00625 +0.3 1.0 hypothetical protein compare
MMP_RS00475 +0.3 1.1 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS04040 +0.3 1.3 hypothetical protein compare
MMP_RS01450 +0.3 1.4 tRNA pseudouridine(38-40) synthase TruA compare
MMP_RS07580 +0.3 1.2 DUF356 domain-containing protein compare
MMP_RS04515 +0.3 1.8 betaine/proline/choline family ABC transporter ATP-binding protein compare
MMP_RS06875 +0.3 1.2 FAD-dependent oxidoreductase compare
MMP_RS03830 +0.3 1.3 exodeoxyribonuclease VII large subunit compare
MMP_RS03485 +0.3 0.6 TIGR00267 family protein compare
MMP_RS04700 +0.3 1.6 hypothetical protein compare
MMP_RS02365 +0.3 1.4 nitrogen fixation compare
MMP_RS02825 +0.3 1.5 mechanosensitive ion channel family protein compare
MMP_RS05415 +0.3 0.8 DUF22 domain-containing protein compare
MMP_RS04275 +0.3 1.3 hydrogenase iron-sulfur subunit compare
MMP_RS00480 +0.3 1.2 hypothetical protein compare
MMP_RS00930 +0.3 0.9 ABC transporter permease compare
MMP_RS08350 +0.3 0.4 hypothetical protein compare
MMP_RS06920 +0.3 1.9 AAA family ATPase compare
MMP_RS05975 +0.3 0.5 hypothetical protein compare
MMP_RS06940 +0.3 0.8 polyprenyl diphosphate synthase compare
MMP_RS08330 +0.3 1.3 NADH-quinone oxidoreductase subunit H compare
MMP_RS03065 +0.3 0.9 AzlC family ABC transporter permease compare
MMP_RS06905 +0.3 0.9 hypothetical protein compare
MMP_RS05420 +0.3 1.3 DUF61 family protein compare
MMP_RS06035 +0.2 1.7 glycosyltransferase family 2 protein compare
MMP_RS00375 +0.2 1.4 ammonium transporter compare
MMP_RS05640 +0.2 1.5 UTP--glucose-1-phosphate uridylyltransferase GalU compare
MMP_RS04885 +0.2 1.6 sulfite exporter TauE/SafE family protein compare
MMP_RS05910 +0.2 0.9 cell division ATPase MinD compare
MMP_RS07615 +0.2 1.5 energy-coupling factor ABC transporter permease compare
MMP_RS07435 +0.2 0.5 GMP synthase subunit A compare
MMP_RS03250 +0.2 1.0 MJ1244 family protein compare
MMP_RS05460 +0.2 1.5 YcaO-related McrA-glycine thioamidation protein compare
MMP_RS05150 +0.2 1.0 hypothetical protein compare
MMP_RS02915 +0.2 1.0 amino acid ABC transporter permease compare
MMP_RS08435 +0.2 0.7 Era-like GTP-binding protein compare
MMP_RS01145 +0.2 1.3 ABC transporter ATP-binding protein compare
MMP_RS01620 +0.2 0.6 hypothetical protein compare
MMP_RS05700 +0.2 1.2 TfuA-related McrA-glycine thioamidation protein compare
MMP_RS06155 +0.2 0.4 DUF4186 domain-containing protein compare
MMP_RS03660 +0.2 1.6 MATE family efflux transporter compare
MMP_RS03615 +0.2 1.6 4Fe-4S binding protein compare
MMP_RS02360 +0.2 1.0 hypothetical protein compare
MMP_RS03100 +0.2 1.1 hypothetical protein compare
MMP_RS00880 +0.2 1.2 ribosome assembly RNA-binding protein YhbY compare
MMP_RS04480 +0.2 2.0 lysine 2 3-aminomutase compare
MMP_RS04215 +0.2 1.5 nickel pincer cofactor biosynthesis protein LarB compare
MMP_RS00530 +0.2 1.5 tRNA pseudouridine(54/55) synthase Pus10 compare
MMP_RS07120 +0.2 1.5 coenzyme F420 hydrogenase subunit alpha compare
MMP_RS08315 +0.2 0.4 S-methyl-5-thioribose-1-phosphate isomerase compare
MMP_RS06500 +0.2 1.3 ATP-binding protein compare
MMP_RS08675 +0.2 0.9 class III signal peptide-containing protein compare
MMP_RS06745 +0.2 1.0 DUF2119 domain-containing protein compare
MMP_RS08705 +0.2 1.6 sulfopyruvate decarboxylase subunit beta compare
MMP_RS01210 +0.2 1.1 sodium:solute symporter compare
MMP_RS03745 +0.2 0.9 phenylacetate--CoA ligase compare
MMP_RS00960 +0.2 1.2 iron export ABC transporter permease subunit FetB compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments

For stress EDTA across organisms