Experiment set5IT053 for Klebsiella michiganensis M5al

Compare to:

D-Sorbitol carbon source

200 most important genes:

  gene name fitness t score description  
BWI76_RS18950 -7.7 -5.3 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS04160 -7.6 -7.3 phosphoserine phosphatase compare
BWI76_RS20350 -7.2 -7.3 amidophosphoribosyltransferase compare
BWI76_RS11850 -6.8 -10.3 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS11965 -6.7 -4.9 orotidine-5'-phosphate decarboxylase compare
BWI76_RS01655 -6.6 -9.1 homoserine O-succinyltransferase compare
BWI76_RS18930 -6.6 -6.0 histidinol-phosphate transaminase compare
BWI76_RS09760 -6.5 -6.1 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS20965 -6.5 -4.7 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS23920 -6.4 -4.4 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS21465 -6.2 -6.1 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS07070 -6.2 -4.3 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS00805 -6.1 -5.2 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS23220 -6.0 -8.3 amino-acid N-acetyltransferase compare
BWI76_RS05840 -6.0 -5.7 glutamate 5-kinase compare
BWI76_RS04470 -6.0 -10.0 carbamoyl phosphate synthase large subunit compare
BWI76_RS00835 -5.9 -12.7 phosphoenolpyruvate carboxylase compare
BWI76_RS00850 -5.9 -10.2 acetylglutamate kinase compare
BWI76_RS04465 -5.9 -5.7 carbamoyl-phosphate synthase small subunit compare
BWI76_RS11860 -5.8 -8.9 anthranilate synthase component I compare
BWI76_RS11855 -5.7 -7.4 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS04675 -5.7 -6.8 3-isopropylmalate dehydrogenase compare
BWI76_RS18940 -5.7 -6.7 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS04670 -5.7 -9.6 3-isopropylmalate dehydratase large subunit compare
BWI76_RS04665 -5.6 -20.4 3-isopropylmalate dehydratase small subunit compare
BWI76_RS01615 -5.6 -10.7 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS07065 -5.5 -9.1 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS04255 -5.4 -10.4 threonine synthase compare
BWI76_RS18920 -5.4 -4.7 ATP phosphoribosyltransferase compare
BWI76_RS04685 -5.3 -11.4 putative leucine operon leader peptide compare
BWI76_RS24285 -5.2 -8.7 cystathionine beta-lyase compare
BWI76_RS00855 -5.2 -8.0 argininosuccinate lyase compare
BWI76_RS00990 -5.2 -9.4 ketol-acid reductoisomerase compare
BWI76_RS18925 -5.2 -6.5 histidinol dehydrogenase compare
BWI76_RS18935 -5.1 -6.3 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS23360 -5.1 -4.9 diaminopimelate decarboxylase compare
BWI76_RS21475 -5.1 -5.4 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS09645 -5.1 -2.1 thioredoxin-disulfide reductase compare
BWI76_RS11840 -5.0 -4.1 tryptophan synthase subunit alpha compare
BWI76_RS05015 -4.9 -4.5 transcriptional regulator compare
BWI76_RS04245 -4.9 -15.6 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS00975 -4.9 -11.7 dihydroxy-acid dehydratase compare
BWI76_RS00980 -4.8 -12.0 PLP-dependent threonine dehydratase compare
BWI76_RS22230 -4.7 -8.8 Sorbitol-6-phosphate 2-dehydrogenase (EC 1.1.1.140) (from data) conserved
BWI76_RS00965 -4.7 -1.9 acetolactate synthase 2 small subunit compare
BWI76_RS20895 -4.7 -4.3 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS05835 -4.7 -3.9 gamma-glutamyl-phosphate reductase compare
BWI76_RS21265 -4.7 -12.8 phosphoribosylformylglycinamidine synthase compare
BWI76_RS25115 -4.6 -7.8 argininosuccinate synthase compare
BWI76_RS09910 -4.5 -16.7 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS04645 -4.5 -5.6 3-dehydroquinase compare
BWI76_RS11845 -4.5 -1.9 tryptophan synthase subunit beta compare
BWI76_RS00785 -4.5 -7.5 cystathionine gamma-synthase compare
BWI76_RS02995 -4.4 -8.7 aspartate carbamoyltransferase compare
BWI76_RS00845 -4.4 -8.1 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS04680 -4.4 -11.1 2-isopropylmalate synthase compare
BWI76_RS25600 -4.3 -1.8 tRNA-Thr compare
BWI76_RS26455 -4.2 -4.1 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
BWI76_RS04240 -4.2 -1.9 thr operon leader peptide compare
BWI76_RS09755 -4.2 -6.2 phosphoserine transaminase compare
BWI76_RS05200 -4.1 -2.8 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS22755 -4.1 -9.5 phosphoadenosine phosphosulfate reductase compare
BWI76_RS18955 -4.1 -7.8 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS22760 -4.1 -8.6 sulfite reductase subunit beta compare
BWI76_RS26085 -4.0 -3.1 3-dehydroquinate synthase compare
BWI76_RS22765 -4.0 -10.7 sulfite reductase subunit alpha compare
BWI76_RS23365 -4.0 -7.6 LysR family transcriptional regulator compare
BWI76_RS04250 -4.0 -5.1 homoserine kinase compare
BWI76_RS20355 -4.0 -3.2 colicin V production protein compare
BWI76_RS00985 -4.0 -8.0 transcriptional regulator IlvY compare
BWI76_RS08385 -4.0 -5.5 citrate (Si)-synthase compare
BWI76_RS27165 -3.9 -4.6 mannitol-1-phosphate 5-dehydrogenase compare
BWI76_RS03010 -3.9 -6.0 ornithine carbamoyltransferase compare
BWI76_RS20435 -3.7 -2.2 chorismate synthase compare
BWI76_RS22220 -3.6 -6.3 PTS glucitol/sorbitol transporter subunit IIB compare
BWI76_RS01610 -3.5 -5.4 phosphoribosylamine--glycine ligase compare
BWI76_RS01210 -3.5 -4.3 tyrosine recombinase XerC compare
BWI76_RS00400 -3.4 -2.2 glutamine synthetase compare
BWI76_RS22690 -3.4 -3.0 adenylyl-sulfate kinase compare
BWI76_RS27385 -3.4 -6.6 orotate phosphoribosyltransferase compare
BWI76_RS23230 -3.3 -2.2 exodeoxyribonuclease V subunit beta compare
BWI76_RS10990 -3.2 -2.0 dihydroorotase compare
BWI76_RS01185 -3.2 -2.2 adenylate cyclase compare
BWI76_RS01200 -3.2 -3.0 diaminopimelate epimerase compare
BWI76_RS22225 -3.0 -7.2 PTS sorbitol transporter subunit IIA compare
BWI76_RS25645 -3.0 -8.7 shikimate dehydrogenase compare
BWI76_RS21100 -2.9 -4.3 nucleoside-diphosphate kinase compare
BWI76_RS22805 -2.9 -8.5 GTP diphosphokinase compare
BWI76_RS26460 -2.9 -4.1 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS02735 -2.8 -4.9 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS22215 -2.8 -5.3 PTS sorbitol transporter subunit IIC compare
BWI76_RS20970 -2.7 -2.2 phosphoribosylglycinamide formyltransferase compare
BWI76_RS17720 -2.7 -2.2 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS27390 -2.7 -3.0 ribonuclease PH compare
BWI76_RS23240 -2.7 -4.0 exonuclease V subunit gamma compare
BWI76_RS09660 -2.7 -3.0 DNA translocase FtsK compare
BWI76_RS26055 -2.7 -6.9 siroheme synthase compare
BWI76_RS20650 -2.6 -2.5 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS15825 -2.5 -3.9 hypothetical protein compare
BWI76_RS25320 -2.4 -9.5 glutamate synthase compare
BWI76_RS00390 -2.4 -6.5 two-component system sensor histidine kinase NtrB compare
BWI76_RS26000 -2.3 -6.6 aspartate aminotransferase family protein compare
BWI76_RS25315 -2.3 -10.3 glutamate synthase large subunit compare
BWI76_RS21070 -2.1 -2.6 outer membrane protein assembly factor BamB compare
BWI76_RS06185 -2.1 -9.5 shikimate kinase II compare
BWI76_RS20640 -2.0 -6.0 cysteine synthase A compare
BWI76_RS14625 -2.0 -1.9 protein TolA compare
BWI76_RS20440 -2.0 -1.3 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS00345 -1.9 -3.1 protein disulfide oxidoreductase DsbA compare
BWI76_RS11900 -1.8 -1.6 cob(I)yrinic acid a,c-diamide adenosyltransferase compare
BWI76_RS27425 -1.8 -1.9 DNA-directed RNA polymerase subunit omega compare
BWI76_RS00180 -1.8 -1.5 F0F1 ATP synthase subunit epsilon compare
BWI76_RS06680 -1.7 -1.4 hypothetical protein compare
BWI76_RS18605 -1.7 -2.7 oxidoreductase molybdopterin-binding protein compare
BWI76_RS01800 -1.7 -2.8 glucose-6-phosphate isomerase compare
BWI76_RS18385 -1.7 -1.7 hypothetical protein compare
BWI76_RS01325 -1.7 -2.2 twin-arginine translocase subunit TatB compare
BWI76_RS27440 -1.7 -3.9 DNA helicase RecG compare
BWI76_RS17370 -1.7 -2.6 nitrate transporter NasD compare
BWI76_RS04955 -1.6 -1.9 hypoxanthine phosphoribosyltransferase compare
BWI76_RS02530 -1.6 -1.4 tRNA dimethylallyltransferase compare
BWI76_RS15830 -1.6 -3.3 hypothetical protein compare
BWI76_RS00960 -1.6 -4.3 acetolactate synthase 2 catalytic subunit compare
BWI76_RS26570 -1.5 -3.4 anion permease compare
BWI76_RS00385 -1.5 -7.4 nitrogen assimilation regulatory protein compare
BWI76_RS15660 -1.5 -1.0 hypothetical protein compare
BWI76_RS19690 -1.5 -2.8 LysR family transcriptional regulator compare
BWI76_RS22695 -1.4 -3.8 sulfate adenylyltransferase compare
BWI76_RS15760 -1.4 -2.0 hypothetical protein compare
BWI76_RS13820 -1.4 -2.5 hypothetical protein compare
BWI76_RS02580 -1.4 -1.7 23S rRNA (guanosine(2251)-2'-O)-methyltransferase compare
BWI76_RS02985 -1.4 -4.4 reactive intermediate/imine deaminase compare
BWI76_RS13435 -1.4 -2.0 hypothetical protein compare
BWI76_RS11335 -1.4 -1.5 tautomerase compare
BWI76_RS23885 -1.4 -1.0 2-octaprenylphenol hydroxylase compare
BWI76_RS08580 -1.3 -2.4 quinolinate synthetase compare
BWI76_RS08405 -1.3 -3.3 succinate dehydrogenase flavoprotein subunit compare
BWI76_RS12090 -1.3 -1.3 HNH endonuclease compare
BWI76_RS09655 -1.3 -4.1 leucine-responsive regulatory protein compare
BWI76_RS15605 -1.3 -2.1 hypothetical protein compare
BWI76_RS23030 -1.3 -2.4 cobalamin biosynthesis protein CbiM compare
BWI76_RS25425 -1.3 -1.7 arginine repressor compare
BWI76_RS21140 -1.2 -1.7 molecular chaperone HscA compare
BWI76_RS04715 -1.2 -1.7 division/cell wall cluster transcriptional repressor MraZ compare
BWI76_RS17975 -1.2 -3.5 tail-specific protease compare
BWI76_RS01890 -1.2 -3.4 transcriptional regulator Zur compare
BWI76_RS21580 -1.2 -1.9 SsrA-binding protein compare
BWI76_RS16315 -1.1 -2.0 SirA-like protein compare
BWI76_RS14075 -1.1 -1.6 TetR family transcriptional regulator compare
BWI76_RS07725 -1.1 -1.3 iron-enterobactin transporter permease compare
BWI76_RS21370 -1.1 -1.5 ATP-dependent RNA helicase SrmB compare
BWI76_RS02815 -1.1 -2.2 fructose-bisphosphatase class I compare
BWI76_RS06535 -1.1 -3.4 endopeptidase La compare
BWI76_RS17300 -1.1 -1.3 tRNA-Tyr compare
BWI76_RS09960 -1.1 -1.7 Lon protease compare
BWI76_RS10835 -1.1 -1.5 hypothetical protein compare
BWI76_RS23480 -1.1 -6.6 EAL domain-containing protein compare
BWI76_RS13590 -1.1 -1.6 hypothetical protein compare
BWI76_RS05005 -1.1 -2.2 polynucleotide adenylyltransferase compare
BWI76_RS07985 -1.0 -0.9 fluoride ion transporter CrcB compare
BWI76_RS17980 -1.0 -3.8 RNA chaperone ProQ compare
BWI76_RS09110 -1.0 -1.8 glutathione ABC transporter permease GsiD compare
BWI76_RS09150 -1.0 -2.6 DNA-binding transcriptional repressor DeoR compare
BWI76_RS20995 -1.0 -3.5 RNA degradosome polyphosphate kinase compare
BWI76_RS22950 -1.0 -1.9 membrane protein compare
BWI76_RS15715 -1.0 -2.4 putative ninG protein compare
BWI76_RS01195 -1.0 -1.3 membrane protein compare
BWI76_RS20380 -1.0 -1.0 tRNA pseudouridine(38-40) synthase TruA compare
BWI76_RS03105 -1.0 -0.9 myo-inosose-2 dehydratase compare
BWI76_RS04270 -1.0 -2.4 transaldolase compare
BWI76_RS15810 -1.0 -2.6 hypothetical protein compare
BWI76_RS08275 -0.9 -1.1 LexA regulated protein compare
BWI76_RS21165 -0.9 -1.5 Fe-S cluster assembly transcriptional regulator IscR compare
BWI76_RS08520 -0.9 -2.2 colicin transporter TolQ compare
BWI76_RS24955 -0.9 -1.7 hypothetical protein compare
BWI76_RS06765 -0.9 -1.7 transcriptional regulator compare
BWI76_RS22840 -0.9 -1.4 transposase compare
BWI76_RS13645 -0.9 -1.3 N-hydroxyarylamine O-acetyltransferase compare
BWI76_RS24260 -0.9 -2.3 hypothetical protein compare
BWI76_RS25065 -0.9 -1.1 polyribonucleotide nucleotidyltransferase compare
BWI76_RS17775 -0.9 -2.4 hypothetical protein compare
BWI76_RS25335 -0.9 -2.0 stringent starvation protein A compare
BWI76_RS21810 -0.9 -1.5 universal stress protein compare
BWI76_RS15685 -0.9 -1.9 hypothetical protein compare
BWI76_RS09530 -0.9 -1.0 hypothetical protein compare
BWI76_RS06635 -0.9 -1.4 methylated-DNA--protein-cysteine methyltransferase compare
BWI76_RS23165 -0.9 -2.5 ATP:cob(I)alamin adenosyltransferase compare
BWI76_RS06530 -0.9 -2.7 ATP-dependent Clp protease ATP-binding subunit ClpX compare
BWI76_RS11105 -0.9 -1.9 aminodeoxychorismate lyase compare
BWI76_RS12680 -0.9 -1.9 oxidoreductase compare
BWI76_RS21480 -0.9 -1.8 phospho-2-dehydro-3-deoxyheptonate aldolase compare
BWI76_RS15360 -0.8 -2.6 hypothetical protein compare
BWI76_RS11980 -0.8 -1.4 DeoR family transcriptional regulator compare
BWI76_RS19035 -0.8 -4.2 dTDP-rhamnosyl transferase compare
BWI76_RS13965 -0.8 -1.8 binding-protein-dependent transport system inner membrane protein compare
BWI76_RS09970 -0.8 -1.5 porin OmpA compare
BWI76_RS23265 -0.8 -1.9 hypothetical protein compare
BWI76_RS05120 -0.8 -3.9 bifunctional glycosyl transferase/transpeptidase compare
BWI76_RS16200 -0.8 -2.1 NAD(P) transhydrogenase subunit beta compare
BWI76_RS09190 -0.8 -2.8 hypothetical protein compare


Specific Phenotypes

For 4 genes in this experiment

For carbon source D-Sorbitol in Klebsiella michiganensis M5al

For carbon source D-Sorbitol across organisms