Experiment set5IT051 for Methanococcus maripaludis S2

200 most important genes:

gene	name	fitness	t score	description
MMP_RS01175		-3.7	-6.4	triphosphoribosyl-dephospho-CoA synthase
MMP_RS06700		-3.2	-19.6	hypothetical protein
MMP_RS06680		-3.0	-18.9	Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain
MMP_RS06685		-2.9	-19.3	formate dehydrogenase H subunit alpha selenocysteine-containing
MMP_RS06355		-2.9	-6.3	molybdenum cofactor biosynthesis protein MoaE
MMP_RS03315		-2.8	-3.0	ferrous iron transport protein A
MMP_RS01020		-2.8	-2.8	3 4-dihydroxy-2-butanone-4-phosphate synthase
MMP_RS01755		-2.6	-3.2	DUF2097 domain-containing protein
MMP_RS05515		-2.5	-13.4	cyclic pyranopterin monophosphate synthase MoaC
MMP_RS08635		-2.5	-3.6	UbiA family prenyltransferase
MMP_RS08820		-2.5	-6.8	hypothetical protein
MMP_RS03435		-2.4	-4.4	ketol-acid reductoisomerase
MMP_RS06400		-2.4	-3.4	4Fe-4S binding protein
MMP_RS06345		-2.3	-15.5	formate dehydrogenase accessory sulfurtransferase FdhD
MMP_RS03600		-2.3	-5.1	triose-phosphate isomerase
MMP_RS03015		-2.3	-13.2	GTP 3' 8-cyclase MoaA
MMP_RS02010		-2.2	-11.9	PHP domain-containing protein
MMP_RS01005		-2.2	-3.4	riboflavin synthase
MMP_RS06715		-2.2	-17.1	cache domain-containing protein
MMP_RS07635		-2.2	-9.2	MogA/MoaB family molybdenum cofactor biosynthesis protein
MMP_RS07445		-2.2	-8.7	helix-turn-helix domain-containing protein
MMP_RS00115		-2.1	-15.7	radical SAM protein
MMP_RS06925		-2.1	-5.2	ribonuclease VapC4
MMP_RS01500		-2.1	-4.4	CBS domain-containing protein
MMP_RS06350		-2.1	-9.6	HesA/MoeB/ThiF family protein
MMP_RS06295		-2.0	-9.0	methanogenesis marker 14 protein
MMP_RS02195		-2.0	-6.8	tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
MMP_RS01265		-2.0	-4.1	hypothetical protein
MMP_RS00895		-2.0	-4.8	hypothetical protein
MMP_RS08460		-1.9	-4.7	proteasome-activating nucleotidase
MMP_RS07005		-1.9	-1.3	4Fe-4S binding protein
MMP_RS00305		-1.9	-3.8	phosphoribosyl-ATP diphosphatase
MMP_RS06730		-1.9	-2.4	phosphopantothenate/pantothenate synthetase
MMP_RS08745		-1.9	-10.4	CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase
MMP_RS05875		-1.9	-5.8	hydroxyethylthiazole kinase
MMP_RS00515		-1.9	-2.5	DUF655 domain-containing protein
MMP_RS03400		-1.9	-5.0	archease
MMP_RS07545		-1.9	-2.6	HTH domain-containing protein
MMP_RS04685		-1.9	-5.4	DUF126 domain-containing protein
MMP_RS08300		-1.9	-2.2	metal-sulfur cluster assembly factor
MMP_RS03025		-1.8	-8.0	molybdenum cofactor guanylyltransferase
MMP_RS06720		-1.8	-10.8	response regulator transcription factor
MMP_RS04780		-1.8	-4.3	ribonuclease P
MMP_RS01220		-1.8	-9.3	hypothetical protein
MMP_RS02135		-1.8	-5.7	DUF5612 domain-containing protein
MMP_RS01610		-1.8	-5.4	hypothetical protein
MMP_RS04585		-1.8	-8.7	AIR synthase related protein
MMP_RS04775		-1.8	-5.0	adenosylhomocysteinase
MMP_RS07575		-1.7	-8.0	RNA ligase partner protein
MMP_RS00295		-1.7	-4.4	gamma carbonic anhydrase family protein
MMP_RS08210		-1.7	-3.8	phosphatidylglycerophosphatase A
MMP_RS07845		-1.7	-4.0	LL-diaminopimelate aminotransferase
MMP_RS05555		-1.7	-3.5	DUF4040 domain-containing protein
MMP_RS06705		-1.7	-6.6	formate/nitrite transporter family protein
MMP_RS03035		-1.7	-5.3	4-hydroxy-tetrahydrodipicolinate synthase
MMP_RS08720		-1.6	-2.2	4Fe-4S binding protein
MMP_RS02235		-1.6	-11.5	CBS domain-containing protein
MMP_RS06625		-1.6	-3.6	DNA primase
MMP_RS07525		-1.6	-9.0	4Fe-4S binding protein
MMP_RS06895		-1.5	-2.5	selenocysteine-specific translation elongation factor
MMP_RS08790		-1.5	-4.1	translation initiation factor IF-2 subunit alpha
MMP_RS05920		-1.5	-1.5	50S ribosomal protein L37e
MMP_RS07730		-1.5	-3.3	pyruvate synthase subunit beta
MMP_RS00300		-1.5	-1.3	6 7-dimethyl-8-ribityllumazine synthase
MMP_RS05540		-1.5	-4.7	hypothetical protein
MMP_RS00685		-1.5	-4.5	2-phospho-L-lactate guanylyltransferase
MMP_RS06285		-1.5	-4.1	precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT
MMP_RS06270		-1.5	-5.9	TIGR00300 family protein
MMP_RS02240		-1.5	-3.2	methanogenesis marker 7 protein
MMP_RS08715		-1.4	-3.3	formylmethanofuran dehydrogenase subunit B
MMP_RS07600		-1.4	-5.1	Ni-sirohydrochlorin a c-diamide synthase
MMP_RS00110		-1.4	-3.5	hypothetical protein
MMP_RS06120		-1.4	-2.8	UPF0147 family protein
MMP_RS08645		-1.4	-7.6	UPF0179 family protein
MMP_RS02800		-1.4	-5.5	nucleotidyltransferase domain-containing protein
MMP_RS02355		-1.3	-4.2	30S ribosomal protein S27ae
MMP_RS06340		-1.3	-9.1	phosphoadenosine phosphosulfate reductase family protein
MMP_RS06020		-1.3	-6.2	archaeoflavoprotein AfpA
MMP_RS07380		-1.3	-2.3	transcription elongation factor Spt5
MMP_RS01225		-1.3	-5.3	DUF5379 domain-containing protein
MMP_RS03640		-1.3	-4.4	archaeal proteasome endopeptidase complex subunit beta
MMP_RS07735		-1.2	-1.8	2-ketoisovalerate ferredoxin oxidoreductase subunit alpha
MMP_RS02165		-1.2	-6.7	tRNA-dihydrouridine synthase
MMP_RS07755		-1.2	-2.2	DUF555 domain-containing protein
MMP_RS02280		-1.2	-1.7	DUF211 domain-containing protein
MMP_RS03960		-1.2	-1.3	hypothetical protein
MMP_RS01325		-1.2	-3.9	dihydroneopterin aldolase family protein
MMP_RS06630		-1.2	-1.5	UPF0058 family protein
MMP_RS07580		-1.2	-3.9	DUF356 domain-containing protein
MMP_RS00290		-1.2	-6.0	hypothetical protein
MMP_RS07765		-1.2	-7.1	sodium:alanine symporter family protein
MMP_RS06885		-1.2	-2.9	50S ribosome-binding GTPase
MMP_RS07605		-1.2	-3.6	diadenylate cyclase
MMP_RS01385		-1.1	-1.1	imidazole glycerol phosphate synthase subunit HisH
MMP_RS02190		-1.1	-2.3	sulfopyruvate decarboxylase subunit alpha
MMP_RS01250		-1.1	-6.5	tRNA (guanine(26)-N(2))-dimethyltransferase
MMP_RS07750		-1.1	-4.1	DUF357 domain-containing protein
MMP_RS01380		-1.1	-4.4	PHP domain-containing protein
MMP_RS07200		-1.1	-4.8	[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
MMP_RS05815		-1.1	-2.2	NOL1/NOP2/sun family putative RNA methylase
MMP_RS05430		-1.0	-4.4	TIGR00288 family NYN domain-containing protein
MMP_RS05265		-1.0	-3.1	2-isopropylmalate synthase
MMP_RS08320		-1.0	-6.5	molybdopterin molybdotransferase MoeA
MMP_RS05245		-1.0	-7.4	archaeosine biosynthesis radical SAM protein RaSEA
MMP_RS08165		-1.0	-2.0	phosphoglycerate dehydrogenase
MMP_RS06475		-1.0	-4.1	FAD-dependent oxidoreductase
MMP_RS01800		-1.0	-3.6	TIGR00303 family protein
MMP_RS01365		-0.9	-4.5	archaeal proteasome endopeptidase complex subunit alpha
MMP_RS08435		-0.9	-2.2	Era-like GTP-binding protein
MMP_RS08200		-0.9	-8.0	archaeosine synthase subunit alpha
MMP_RS00315		-0.9	-3.6	Nif3-like dinuclear metal center hexameric protein
MMP_RS07365		-0.9	-7.6	2-phosphoglycerate kinase
MMP_RS07695		-0.9	-6.3	DUF3236 domain-containing protein
MMP_RS05445		-0.9	-5.7	CoB--CoM heterodisulfide reductase subunit B
MMP_RS01720		-0.9	-1.0	replication factor C large subunit
MMP_RS01830		-0.9	-1.7	tRNA-Val
MMP_RS02885		-0.8	-6.4	molybdopterin biosynthesis protein
MMP_RS01980		-0.8	-6.5	trimeric intracellular cation channel family protein
MMP_RS06485		-0.8	-1.4	zinc ribbon domain-containing protein
MMP_RS06865		-0.8	-2.2	HypC/HybG/HupF family hydrogenase formation chaperone
MMP_RS08915		-0.8	-1.7	2 5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase
MMP_RS00320		-0.8	-2.6	class I SAM-dependent methyltransferase
MMP_RS04890		-0.8	-0.8	adenylyltransferase/cytidyltransferase family protein
MMP_RS03095		-0.8	-5.1	diphthine synthase
MMP_RS04615		-0.8	-4.3	PDGLE domain-containing protein
MMP_RS07700		-0.8	-4.4	DUF1188 domain-containing protein
MMP_RS00725		-0.8	-3.9	5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC
MMP_RS00730		-0.8	-4.2	5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB
MMP_RS05545		-0.8	-3.0	pyridoxal phosphate-dependent aminotransferase
MMP_RS05510		-0.8	-5.9	Rrf2 family transcriptional regulator
MMP_RS01180		-0.8	-1.1	XTP/dITP diphosphatase
MMP_RS04605		-0.8	-4.7	cobalt ECF transporter T component CbiQ
MMP_RS04850		-0.8	-6.5	UPF0254 family protein
MMP_RS03580		-0.8	-2.4	signal recognition particle-docking protein FtsY
MMP_RS07425		-0.8	-3.8	GTP-binding protein
MMP_RS05765		-0.8	-3.8	M42 family metallopeptidase
MMP_RS02875		-0.8	-5.6	chorismate pyruvate-lyase family protein
MMP_RS01840		-0.7	-3.6	TIGR00289 family protein
MMP_RS03155		-0.7	-5.0	precorrin-6A reductase
MMP_RS06215		-0.7	-2.4	30S ribosomal protein S6e
MMP_RS00810		-0.7	-4.4	topoisomerase DNA-binding C4 zinc finger domain-containing protein
MMP_RS01030		-0.7	-1.9	MTAP family purine nucleoside phosphorylase
MMP_RS08330		-0.7	-4.3	NADH-quinone oxidoreductase subunit H
MMP_RS06105		-0.7	-4.6	hydrogenase maturation peptidase HycI
MMP_RS00620		-0.7	-5.3	4Fe-4S binding protein
MMP_RS07630		-0.7	-1.7	ATP-binding cassette domain-containing protein
MMP_RS09020		-0.7	-1.8	hypothetical protein
MMP_RS02345		-0.7	-2.9	GTP-dependent dephospho-CoA kinase family protein
MMP_RS00675		-0.7	-1.4	nitroreductase family protein
MMP_RS05550		-0.7	-0.9	cation:proton antiporter
MMP_RS07435		-0.7	-1.2	GMP synthase subunit A
MMP_RS00050		-0.7	-4.2	AarF/UbiB family protein
MMP_RS02245		-0.7	-2.7	hypothetical protein
MMP_RS02900		-0.7	-0.6	imidazoleglycerol-phosphate dehydratase HisB
MMP_RS03555		-0.7	-3.8	transcriptional regulator
MMP_RS01985		-0.6	-2.7	F420-dependent methylenetetrahydromethanopterin dehydrogenase
MMP_RS00040		-0.6	-3.3	TIGR03576 family pyridoxal phosphate-dependent enzyme
MMP_RS05345		-0.6	-3.2	hypothetical protein
MMP_RS02145		-0.6	-2.7	winged helix-turn-helix transcriptional regulator
MMP_RS07385		-0.6	-1.2	protein translocase SEC61 complex subunit gamma
MMP_RS05095		-0.6	-3.7	CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon
MMP_RS07535		-0.6	-3.9	4Fe-4S binding protein
MMP_RS03470		-0.6	-4.3	phosphoadenosine phosphosulfate reductase family protein
MMP_RS05060		-0.6	-4.9	AAA family ATPase
MMP_RS07190		-0.6	-3.9	chromosome segregation protein SMC
MMP_RS04620		-0.6	-4.4	cobalt transporter CbiM
MMP_RS06855		-0.6	-4.5	hypothetical protein
MMP_RS03385		-0.6	-1.1	cation diffusion facilitator family transporter
MMP_RS01795		-0.6	-1.5	methanogenesis marker 6 protein
MMP_RS06200		-0.6	-4.8	M24 family metallopeptidase
MMP_RS00120		-0.6	-3.5	LysR family transcriptional regulator
MMP_RS05070		-0.6	-3.9	4Fe-4S dicluster domain-containing protein
MMP_RS05845		-0.6	-1.4	tRNA-intron lyase
MMP_RS01335		-0.6	-2.4	prefoldin subunit beta
MMP_RS05425		-0.6	-2.3	monovalent cation/H+ antiporter complex subunit F
MMP_RS02130		-0.5	-2.2	zinc metalloprotease HtpX
MMP_RS03305		-0.5	-3.7	winged helix-turn-helix domain-containing protein
MMP_RS06870		-0.5	-3.0	DedA family protein
MMP_RS05075		-0.5	-4.3	acetyl-CoA decarbonylase/synthase complex subunit gamma
MMP_RS05065		-0.5	-3.0	CooT family nickel-binding protein
MMP_RS08650		-0.5	-1.6	glutamine--fructose-6-phosphate transaminase (isomerizing)
MMP_RS01780		-0.5	-3.8	TrmJ/YjtD family RNA methyltransferase
MMP_RS00985		-0.5	-3.1	CDC48 family AAA ATPase
MMP_RS06940		-0.5	-1.1	polyprenyl diphosphate synthase
MMP_RS05090		-0.5	-3.9	CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta
MMP_RS00695		-0.5	-0.7	biotin--[acetyl-CoA-carboxylase] ligase
MMP_RS03250		-0.5	-1.8	MJ1244 family protein
MMP_RS06930		-0.5	-3.8	MBL fold metallo-hydrolase
MMP_RS00830		-0.5	-2.5	purine phosphoribosyltransferase family protein
MMP_RS03490		-0.5	-1.6	DUF2115 domain-containing protein
MMP_RS08445		-0.5	-1.7	DUF2099 family protein
MMP_RS06395		-0.5	-2.6	ThiF family adenylyltransferase
MMP_RS05100		-0.5	-4.1	CO dehydrogenase/acetyl-CoA synthase complex subunit alpha
MMP_RS06175		-0.5	-3.2	winged helix-turn-helix transcriptional regulator
MMP_RS07860		-0.5	-0.6	hypothetical protein
MMP_RS08240		-0.5	-3.5	methanogenesis marker 16 metalloprotein
MMP_RS04710		-0.5	-0.8	hypothetical protein
MMP_RS00915		-0.5	-2.6	DUF116 domain-containing protein
MMP_RS06525		-0.5	-1.1	YciI family protein
MMP_RS05440		-0.5	-3.3	winged helix-turn-helix transcriptional regulator

Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments