Experiment set5IT051 for Klebsiella michiganensis M5al

Compare to:

m-Inositol carbon source

200 most important genes:

  gene name fitness t score description  
BWI76_RS18950 -7.8 -5.4 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS04675 -7.1 -6.9 3-isopropylmalate dehydrogenase compare
BWI76_RS05840 -7.0 -4.8 glutamate 5-kinase compare
BWI76_RS18930 -6.8 -6.1 histidinol-phosphate transaminase compare
BWI76_RS11965 -6.8 -5.7 orotidine-5'-phosphate decarboxylase compare
BWI76_RS07070 -6.4 -4.4 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS05015 -6.4 -4.4 transcriptional regulator compare
BWI76_RS18940 -6.3 -7.4 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS04670 -6.2 -10.3 3-isopropylmalate dehydratase large subunit compare
BWI76_RS00990 -6.1 -8.0 ketol-acid reductoisomerase compare
BWI76_RS18920 -5.7 -5.5 ATP phosphoribosyltransferase compare
BWI76_RS04250 -5.7 -8.3 homoserine kinase compare
BWI76_RS01615 -5.6 -10.8 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS20355 -5.6 -3.9 colicin V production protein compare
BWI76_RS26085 -5.6 -3.8 3-dehydroquinate synthase compare
BWI76_RS04470 -5.6 -11.3 carbamoyl phosphate synthase large subunit compare
BWI76_RS18925 -5.5 -8.4 histidinol dehydrogenase compare
BWI76_RS00850 -5.5 -10.9 acetylglutamate kinase compare
BWI76_RS11860 -5.5 -10.5 anthranilate synthase component I compare
BWI76_RS04645 -5.5 -6.9 3-dehydroquinase compare
BWI76_RS21265 -5.4 -13.3 phosphoribosylformylglycinamidine synthase compare
BWI76_RS25115 -5.4 -6.6 argininosuccinate synthase compare
BWI76_RS00805 -5.3 -5.6 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS20965 -5.3 -3.7 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS01655 -5.2 -7.8 homoserine O-succinyltransferase compare
BWI76_RS22805 -5.2 -11.7 GTP diphosphokinase compare
BWI76_RS05835 -5.2 -3.6 gamma-glutamyl-phosphate reductase compare
BWI76_RS04160 -5.2 -6.3 phosphoserine phosphatase compare
BWI76_RS11850 -5.2 -12.5 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS00855 -5.1 -8.6 argininosuccinate lyase compare
BWI76_RS09645 -5.1 -2.1 thioredoxin-disulfide reductase compare
BWI76_RS20895 -5.1 -7.0 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS00980 -5.1 -12.7 PLP-dependent threonine dehydratase compare
BWI76_RS04465 -5.1 -6.0 carbamoyl-phosphate synthase small subunit compare
BWI76_RS09755 -5.0 -7.5 phosphoserine transaminase compare
BWI76_RS23920 -5.0 -6.6 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS04255 -5.0 -10.6 threonine synthase compare
BWI76_RS00965 -4.8 -2.0 acetolactate synthase 2 small subunit compare
BWI76_RS04685 -4.8 -10.0 putative leucine operon leader peptide compare
BWI76_RS04245 -4.8 -17.3 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS18935 -4.7 -10.1 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS18955 -4.7 -6.2 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS00785 -4.6 -7.0 cystathionine gamma-synthase compare
BWI76_RS11855 -4.6 -9.6 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS04665 -4.5 -18.2 3-isopropylmalate dehydratase small subunit compare
BWI76_RS23915 -4.5 -2.5 5-formyltetrahydrofolate cyclo-ligase compare
BWI76_RS02995 -4.4 -9.8 aspartate carbamoyltransferase compare
BWI76_RS00985 -4.4 -7.8 transcriptional regulator IlvY compare
BWI76_RS04240 -4.3 -2.0 thr operon leader peptide compare
BWI76_RS20350 -4.3 -8.9 amidophosphoribosyltransferase compare
BWI76_RS00835 -4.3 -12.5 phosphoenolpyruvate carboxylase compare
BWI76_RS21475 -4.2 -4.7 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS03095 -4.2 -7.1 Inositol 2-dehydrogenase (EC 1.1.1.18) (from data) conserved
BWI76_RS07065 -4.2 -8.2 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS23360 -4.2 -4.7 diaminopimelate decarboxylase compare
BWI76_RS02815 -4.2 -2.9 fructose-bisphosphatase class I compare
BWI76_RS03010 -4.2 -8.1 ornithine carbamoyltransferase compare
BWI76_RS24285 -4.1 -7.6 cystathionine beta-lyase compare
BWI76_RS09760 -4.1 -4.9 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS09660 -4.0 -2.8 DNA translocase FtsK compare
BWI76_RS00975 -4.0 -7.1 dihydroxy-acid dehydratase compare
BWI76_RS22760 -4.0 -8.2 sulfite reductase subunit beta compare
BWI76_RS08385 -4.0 -2.4 citrate (Si)-synthase compare
BWI76_RS27385 -3.9 -8.7 orotate phosphoribosyltransferase compare
BWI76_RS23365 -3.9 -4.3 LysR family transcriptional regulator compare
BWI76_RS20435 -3.9 -2.3 chorismate synthase compare
BWI76_RS00845 -3.8 -7.4 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS22765 -3.8 -9.8 sulfite reductase subunit alpha compare
BWI76_RS09910 -3.8 -15.0 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS11840 -3.8 -4.3 tryptophan synthase subunit alpha compare
BWI76_RS23220 -3.8 -6.5 amino-acid N-acetyltransferase compare
BWI76_RS11845 -3.7 -3.7 tryptophan synthase subunit beta compare
BWI76_RS01610 -3.7 -7.7 phosphoribosylamine--glycine ligase compare
BWI76_RS23240 -3.7 -3.5 exonuclease V subunit gamma compare
BWI76_RS27440 -3.6 -5.4 DNA helicase RecG compare
BWI76_RS00400 -3.5 -2.3 glutamine synthetase compare
BWI76_RS10990 -3.5 -4.0 dihydroorotase compare
BWI76_RS04680 -3.5 -9.1 2-isopropylmalate synthase compare
BWI76_RS21465 -3.4 -5.7 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS01210 -3.4 -2.5 tyrosine recombinase XerC compare
BWI76_RS08535 -3.4 -3.1 translocation protein TolB compare
BWI76_RS22755 -3.4 -8.5 phosphoadenosine phosphosulfate reductase compare
BWI76_RS00140 -3.2 -1.9 phosphate transport system regulator PhoU compare
BWI76_RS20640 -3.2 -6.3 cysteine synthase A compare
BWI76_RS22690 -3.0 -4.4 adenylyl-sulfate kinase compare
BWI76_RS03105 -2.9 -1.7 myo-inosose-2 dehydratase compare
BWI76_RS01185 -2.9 -2.8 adenylate cyclase compare
BWI76_RS17720 -2.9 -2.4 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS26055 -2.8 -9.5 siroheme synthase compare
BWI76_RS03090 -2.7 -13.2 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase IolD (EC 3.7.1.22) (from data) conserved
BWI76_RS15825 -2.7 -2.8 hypothetical protein compare
BWI76_RS02735 -2.6 -6.1 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS03100 -2.6 -4.3 protein iolH compare
BWI76_RS23230 -2.6 -3.8 exodeoxyribonuclease V subunit beta compare
BWI76_RS26460 -2.5 -5.1 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS03075 -2.5 -8.5 5-deoxy-D-glucuronate isomerase (EC 5.3.1.30) (from data) conserved
BWI76_RS23265 -2.5 -3.3 hypothetical protein compare
BWI76_RS25645 -2.4 -8.9 shikimate dehydrogenase compare
BWI76_RS26455 -2.4 -3.8 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
BWI76_RS26570 -2.3 -4.1 anion permease compare
BWI76_RS00180 -2.3 -1.9 F0F1 ATP synthase subunit epsilon compare
BWI76_RS08520 -2.2 -4.5 colicin transporter TolQ compare
BWI76_RS05200 -2.2 -3.4 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS03085 -2.1 -10.8 5-dehydro-2-deoxygluconokinase (EC 2.7.1.92); possible 5-dehydro-2-deoxyphosphogluconate aldolase DUF2090 (EC 4.1.2.29) (from data) conserved
BWI76_RS00390 -2.0 -5.3 two-component system sensor histidine kinase NtrB compare
BWI76_RS09640 -2.0 -4.1 cysteine/glutathione ABC transporter permease/ATP-binding protein CydD compare
BWI76_RS27390 -2.0 -2.2 ribonuclease PH compare
BWI76_RS25320 -2.0 -5.0 glutamate synthase compare
BWI76_RS20650 -1.9 -3.1 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS20970 -1.9 -2.1 phosphoribosylglycinamide formyltransferase compare
BWI76_RS09970 -1.9 -3.4 porin OmpA compare
BWI76_RS26390 -1.8 -4.1 cell division protein FtsX compare
BWI76_RS20440 -1.8 -2.3 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS26000 -1.8 -4.5 aspartate aminotransferase family protein compare
BWI76_RS24100 -1.8 -5.1 YggS family pyridoxal phosphate enzyme compare
BWI76_RS18730 -1.8 -5.5 LysR family transcriptional regulator conserved
BWI76_RS17290 -1.8 -6.2 formyltetrahydrofolate deformylase compare
BWI76_RS01800 -1.8 -4.3 glucose-6-phosphate isomerase compare
BWI76_RS17980 -1.7 -4.8 RNA chaperone ProQ compare
BWI76_RS04510 -1.7 -2.7 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) compare
BWI76_RS02530 -1.7 -2.9 tRNA dimethylallyltransferase compare
BWI76_RS08525 -1.7 -3.2 colicin transporter compare
BWI76_RS00345 -1.7 -3.5 protein disulfide oxidoreductase DsbA compare
BWI76_RS26075 -1.7 -4.1 DNA adenine methylase compare
BWI76_RS03070 -1.7 -5.0 Methylmalonate-semialdehyde dehydrogenase [inositol] (EC 1.2.1.27) (from data) conserved
BWI76_RS01885 -1.7 -1.8 CsbD family protein compare
BWI76_RS25315 -1.7 -8.7 glutamate synthase large subunit compare
BWI76_RS06525 -1.7 -4.0 ATP-dependent Clp protease proteolytic subunit compare
BWI76_RS27430 -1.6 -1.6 (p)ppGpp synthetase compare
BWI76_RS20995 -1.6 -4.1 RNA degradosome polyphosphate kinase compare
BWI76_RS25335 -1.6 -2.3 stringent starvation protein A compare
BWI76_RS08530 -1.6 -3.1 protein TolA compare
BWI76_RS23480 -1.5 -9.1 EAL domain-containing protein compare
BWI76_RS16275 -1.5 -2.9 fumarate hydratase FumA compare
BWI76_RS15830 -1.5 -2.3 hypothetical protein compare
BWI76_RS15835 -1.5 -1.0 hypothetical protein compare
BWI76_RS18735 -1.5 -3.9 tautomerase family protein compare
BWI76_RS26395 -1.5 -2.7 cell division protein FtsE compare
BWI76_RS01200 -1.5 -2.3 diaminopimelate epimerase compare
BWI76_RS05260 -1.4 -1.9 chaperone compare
BWI76_RS01385 -1.4 -2.1 potassium transporter compare
BWI76_RS27435 -1.4 -4.7 tRNA (guanosine(18)-2'-O)-methyltransferase TrmH compare
BWI76_RS06340 -1.4 -1.5 hypothetical protein compare
BWI76_RS08980 -1.3 -1.5 DNA starvation/stationary phase protection protein compare
BWI76_RS00960 -1.3 -3.5 acetolactate synthase 2 catalytic subunit compare
BWI76_RS25065 -1.3 -1.9 polyribonucleotide nucleotidyltransferase compare
BWI76_RS04530 -1.3 -1.7 peptidylprolyl isomerase SurA compare
BWI76_RS01565 -1.3 -2.0 NADH pyrophosphatase compare
BWI76_RS12420 -1.3 -1.4 peptide ABC transporter substrate-binding protein SapA compare
BWI76_RS26685 -1.2 -3.2 glutathione-disulfide reductase compare
BWI76_RS20910 -1.2 -6.4 glycine cleavage system transcriptional repressor compare
BWI76_RS06185 -1.2 -5.2 shikimate kinase II compare
BWI76_RS22695 -1.2 -3.3 sulfate adenylyltransferase compare
BWI76_RS19690 -1.2 -1.9 LysR family transcriptional regulator compare
BWI76_RS01275 -1.2 -4.0 LysR family transcriptional regulator compare
BWI76_RS21100 -1.2 -3.2 nucleoside-diphosphate kinase compare
BWI76_RS05120 -1.2 -5.7 bifunctional glycosyl transferase/transpeptidase compare
BWI76_RS07465 -1.1 -2.8 TetR family transcriptional regulator compare
BWI76_RS18165 -1.1 -2.0 NUDIX pyrophosphatase compare
BWI76_RS07510 -1.1 -2.4 hypothetical protein compare
BWI76_RS13215 -1.1 -1.4 type I glyceraldehyde-3-phosphate dehydrogenase compare
BWI76_RS06730 -1.1 -2.8 lac repressor compare
BWI76_RS00385 -1.1 -4.8 nitrogen assimilation regulatory protein compare
BWI76_RS24075 -1.1 -2.8 glutathione synthase compare
BWI76_RS27875 -1.1 -1.3 membrane protein compare
BWI76_RS25160 -1.1 -1.7 transcription elongation factor GreA compare
BWI76_RS15665 -1.1 -3.2 hypothetical protein compare
BWI76_RS08580 -1.1 -2.8 quinolinate synthetase compare
BWI76_RS25070 -1.1 -1.3 hypothetical protein compare
BWI76_RS01170 -1.1 -3.4 uroporphyrinogen-III C-methyltransferase compare
BWI76_RS15810 -1.1 -4.5 hypothetical protein compare
BWI76_RS14775 -1.1 -1.6 creatinine amidohydrolase compare
BWI76_RS09615 -1.1 -2.0 ATP-dependent Clp protease ATP-binding subunit ClpA compare
BWI76_RS01070 -1.1 -3.5 thiol reductase thioredoxin compare
BWI76_RS21480 -1.1 -3.3 phospho-2-dehydro-3-deoxyheptonate aldolase compare
BWI76_RS04705 -1.0 -4.5 DNA-binding transcriptional regulator FruR compare
BWI76_RS09520 -1.0 -2.1 arginine ABC transporter ATP-binding protein ArtP compare
BWI76_RS15760 -1.0 -1.7 hypothetical protein compare
BWI76_RS11565 -1.0 -6.5 DeoR family transcriptional regulator compare
BWI76_RS19685 -1.0 -3.3 lysine transporter compare
BWI76_RS24900 -1.0 -1.3 DeoR family transcriptional regulator compare
BWI76_RS19215 -1.0 -1.8 proline-specific peptidase compare
BWI76_RS25505 -1.0 -3.8 RNase E specificity factor CsrD compare
BWI76_RS07725 -1.0 -1.3 iron-enterobactin transporter permease compare
BWI76_RS09190 -1.0 -2.4 hypothetical protein compare
BWI76_RS15060 -1.0 -1.9 MarR family transcriptional regulator compare
BWI76_RS16360 -1.0 -1.4 electron transport complex subunit RsxB compare
BWI76_RS27815 -1.0 -6.6 acetolactate synthase catalytic subunit compare
BWI76_RS01350 -1.0 -0.8 NAD(P)H-flavin reductase compare
BWI76_RS21360 -1.0 -4.7 L-aspartate oxidase compare
BWI76_RS03880 -1.0 -1.9 homoprotocatechuate degradation operon regulator, HpaR compare
BWI76_RS09670 -1.0 -3.7 recombination factor protein RarA compare
BWI76_RS17975 -0.9 -3.7 tail-specific protease compare
BWI76_RS22120 -0.9 -5.3 glutamate--cysteine ligase compare
BWI76_RS22420 -0.9 -1.5 LacI family transcriptional regulator compare
BWI76_RS04270 -0.9 -3.0 transaldolase compare
BWI76_RS19325 -0.9 -1.0 mandelate racemase compare
BWI76_RS26620 -0.9 -1.1 Fe-S biogenesis protein NfuA compare
BWI76_RS16955 -0.9 -1.4 hypothetical protein compare
BWI76_RS25600 -0.9 -0.9 tRNA-Thr compare


Specific Phenotypes

For 6 genes in this experiment

For carbon source m-Inositol in Klebsiella michiganensis M5al

For carbon source m-Inositol across organisms