Experiment set5IT050 for Methanococcus maripaludis S2

200 most important genes:

gene	name	fitness	t score	description
MMP_RS01175		-3.9	-10.9	triphosphoribosyl-dephospho-CoA synthase
MMP_RS06700		-3.8	-17.2	hypothetical protein
MMP_RS06685		-3.3	-19.4	formate dehydrogenase H subunit alpha selenocysteine-containing
MMP_RS02900		-3.3	-1.3	imidazoleglycerol-phosphate dehydratase HisB
MMP_RS06680		-3.2	-22.2	Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain
MMP_RS08820		-2.9	-9.2	hypothetical protein
MMP_RS02010		-2.8	-12.9	PHP domain-containing protein
MMP_RS07005		-2.7	-1.4	4Fe-4S binding protein
MMP_RS06345		-2.7	-15.5	formate dehydrogenase accessory sulfurtransferase FdhD
MMP_RS05515		-2.7	-10.4	cyclic pyranopterin monophosphate synthase MoaC
MMP_RS02280		-2.6	-2.3	DUF211 domain-containing protein
MMP_RS01020		-2.5	-2.6	3 4-dihydroxy-2-butanone-4-phosphate synthase
MMP_RS03015		-2.5	-14.1	GTP 3' 8-cyclase MoaA
MMP_RS06355		-2.5	-5.9	molybdenum cofactor biosynthesis protein MoaE
MMP_RS06350		-2.4	-9.8	HesA/MoeB/ThiF family protein
MMP_RS08635		-2.4	-3.3	UbiA family prenyltransferase
MMP_RS07635		-2.4	-9.0	MogA/MoaB family molybdenum cofactor biosynthesis protein
MMP_RS07445		-2.3	-8.2	helix-turn-helix domain-containing protein
MMP_RS02235		-2.3	-15.3	CBS domain-containing protein
MMP_RS01265		-2.3	-4.1	hypothetical protein
MMP_RS06715		-2.3	-17.2	cache domain-containing protein
MMP_RS06720		-2.2	-12.5	response regulator transcription factor
MMP_RS08300		-2.2	-2.5	metal-sulfur cluster assembly factor
MMP_RS00300		-2.1	-1.4	6 7-dimethyl-8-ribityllumazine synthase
MMP_RS06705		-2.1	-8.2	formate/nitrite transporter family protein
MMP_RS04780		-2.1	-4.9	ribonuclease P
MMP_RS08460		-2.0	-4.8	proteasome-activating nucleotidase
MMP_RS02355		-2.0	-4.6	30S ribosomal protein S27ae
MMP_RS01795		-2.0	-2.3	methanogenesis marker 6 protein
MMP_RS01005		-2.0	-3.2	riboflavin synthase
MMP_RS00515		-2.0	-2.3	DUF655 domain-containing protein
MMP_RS02195		-2.0	-4.8	tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
MMP_RS03025		-1.9	-7.3	molybdenum cofactor guanylyltransferase
MMP_RS06285		-1.9	-4.4	precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT
MMP_RS00115		-1.9	-12.8	radical SAM protein
MMP_RS08720		-1.8	-3.1	4Fe-4S binding protein
MMP_RS07525		-1.8	-10.4	4Fe-4S binding protein
MMP_RS07845		-1.8	-4.0	LL-diaminopimelate aminotransferase
MMP_RS04685		-1.8	-6.9	DUF126 domain-containing protein
MMP_RS03435		-1.8	-3.1	ketol-acid reductoisomerase
MMP_RS01500		-1.8	-4.0	CBS domain-containing protein
MMP_RS06020		-1.8	-7.2	archaeoflavoprotein AfpA
MMP_RS03315		-1.8	-2.8	ferrous iron transport protein A
MMP_RS08745		-1.8	-8.2	CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase
MMP_RS01220		-1.8	-9.8	hypothetical protein
MMP_RS02135		-1.8	-5.0	DUF5612 domain-containing protein
MMP_RS06895		-1.8	-3.4	selenocysteine-specific translation elongation factor
MMP_RS00305		-1.7	-2.2	phosphoribosyl-ATP diphosphatase
MMP_RS06295		-1.7	-8.8	methanogenesis marker 14 protein
MMP_RS06925		-1.7	-3.7	ribonuclease VapC4
MMP_RS07575		-1.7	-6.9	RNA ligase partner protein
MMP_RS01225		-1.7	-8.9	DUF5379 domain-containing protein
MMP_RS05875		-1.6	-6.0	hydroxyethylthiazole kinase
MMP_RS00895		-1.6	-3.6	hypothetical protein
MMP_RS06340		-1.6	-10.7	phosphoadenosine phosphosulfate reductase family protein
MMP_RS08790		-1.6	-3.3	translation initiation factor IF-2 subunit alpha
MMP_RS01610		-1.6	-5.0	hypothetical protein
MMP_RS07545		-1.6	-2.5	HTH domain-containing protein
MMP_RS06400		-1.5	-3.0	4Fe-4S binding protein
MMP_RS04775		-1.5	-4.0	adenosylhomocysteinase
MMP_RS05540		-1.5	-4.7	hypothetical protein
MMP_RS03475		-1.5	-1.1	hypothetical protein
MMP_RS04585		-1.5	-8.5	AIR synthase related protein
MMP_RS02800		-1.5	-6.2	nucleotidyltransferase domain-containing protein
MMP_RS00685		-1.4	-4.4	2-phospho-L-lactate guanylyltransferase
MMP_RS06475		-1.4	-7.4	FAD-dependent oxidoreductase
MMP_RS01755		-1.4	-1.0	DUF2097 domain-containing protein
MMP_RS01365		-1.4	-3.5	archaeal proteasome endopeptidase complex subunit alpha
MMP_RS02240		-1.4	-6.0	methanogenesis marker 7 protein
MMP_RS08645		-1.4	-6.7	UPF0179 family protein
MMP_RS09020		-1.4	-2.4	hypothetical protein
MMP_RS07735		-1.4	-1.7	2-ketoisovalerate ferredoxin oxidoreductase subunit alpha
MMP_RS06270		-1.4	-5.4	TIGR00300 family protein
MMP_RS08715		-1.4	-2.4	formylmethanofuran dehydrogenase subunit B
MMP_RS07765		-1.3	-9.3	sodium:alanine symporter family protein
MMP_RS00295		-1.3	-3.4	gamma carbonic anhydrase family protein
MMP_RS06730		-1.3	-3.1	phosphopantothenate/pantothenate synthetase
MMP_RS00675		-1.3	-2.1	nitroreductase family protein
MMP_RS06625		-1.3	-3.3	DNA primase
MMP_RS03035		-1.3	-3.7	4-hydroxy-tetrahydrodipicolinate synthase
MMP_RS06315		-1.2	-1.3	cobalt-precorrin-7 (C(5))-methyltransferase
MMP_RS08210		-1.2	-3.4	phosphatidylglycerophosphatase A
MMP_RS03400		-1.2	-3.0	archease
MMP_RS07600		-1.2	-2.3	Ni-sirohydrochlorin a c-diamide synthase
MMP_RS06865		-1.2	-2.1	HypC/HybG/HupF family hydrogenase formation chaperone
MMP_RS03640		-1.2	-4.1	archaeal proteasome endopeptidase complex subunit beta
MMP_RS07730		-1.2	-2.7	pyruvate synthase subunit beta
MMP_RS05920		-1.2	-1.2	50S ribosomal protein L37e
MMP_RS04890		-1.1	-1.1	adenylyltransferase/cytidyltransferase family protein
MMP_RS05845		-1.1	-2.4	tRNA-intron lyase
MMP_RS05555		-1.1	-2.4	DUF4040 domain-containing protein
MMP_RS05815		-1.1	-2.4	NOL1/NOP2/sun family putative RNA methylase
MMP_RS02165		-1.1	-7.7	tRNA-dihydrouridine synthase
MMP_RS00290		-1.1	-7.2	hypothetical protein
MMP_RS08320		-1.1	-6.8	molybdopterin molybdotransferase MoeA
MMP_RS00110		-1.1	-3.8	hypothetical protein
MMP_RS01180		-1.1	-1.2	XTP/dITP diphosphatase
MMP_RS01700		-1.0	-1.3	dihydroxy-acid dehydratase
MMP_RS02875		-1.0	-5.7	chorismate pyruvate-lyase family protein
MMP_RS01250		-1.0	-4.8	tRNA (guanine(26)-N(2))-dimethyltransferase
MMP_RS06885		-1.0	-2.7	50S ribosome-binding GTPase
MMP_RS01980		-1.0	-8.3	trimeric intracellular cation channel family protein
MMP_RS01385		-1.0	-1.0	imidazole glycerol phosphate synthase subunit HisH
MMP_RS00735		-1.0	-3.0	5 10-methenyltetrahydromethanopterin hydrogenase
MMP_RS05245		-1.0	-6.9	archaeosine biosynthesis radical SAM protein RaSEA
MMP_RS00060		-1.0	-1.6	3-dehydroquinate synthase II
MMP_RS08915		-1.0	-2.2	2 5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase
MMP_RS00320		-1.0	-2.5	class I SAM-dependent methyltransferase
MMP_RS01800		-1.0	-3.4	TIGR00303 family protein
MMP_RS05445		-1.0	-6.2	CoB--CoM heterodisulfide reductase subunit B
MMP_RS01985		-1.0	-4.9	F420-dependent methylenetetrahydromethanopterin dehydrogenase
MMP_RS03600		-1.0	-1.4	triose-phosphate isomerase
MMP_RS01325		-1.0	-1.9	dihydroneopterin aldolase family protein
MMP_RS07385		-0.9	-1.7	protein translocase SEC61 complex subunit gamma
MMP_RS07695		-0.9	-6.5	DUF3236 domain-containing protein
MMP_RS05430		-0.9	-3.9	TIGR00288 family NYN domain-containing protein
MMP_RS01380		-0.9	-3.5	PHP domain-containing protein
MMP_RS05265		-0.9	-2.2	2-isopropylmalate synthase
MMP_RS00315		-0.9	-5.3	Nif3-like dinuclear metal center hexameric protein
MMP_RS07750		-0.9	-2.3	DUF357 domain-containing protein
MMP_RS03555		-0.9	-6.5	transcriptional regulator
MMP_RS00725		-0.9	-6.1	5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC
MMP_RS03445		-0.9	-1.4	methanogenesis marker 17 protein
MMP_RS07580		-0.9	-3.6	DUF356 domain-containing protein
MMP_RS07350		-0.9	-2.4	preprotein translocase subunit Sec61beta
MMP_RS07755		-0.9	-1.0	DUF555 domain-containing protein
MMP_RS02885		-0.9	-7.2	molybdopterin biosynthesis protein
MMP_RS06105		-0.8	-5.4	hydrogenase maturation peptidase HycI
MMP_RS06395		-0.8	-2.9	ThiF family adenylyltransferase
MMP_RS08200		-0.8	-7.4	archaeosine synthase subunit alpha
MMP_RS05765		-0.8	-3.7	M42 family metallopeptidase
MMP_RS06120		-0.8	-2.4	UPF0147 family protein
MMP_RS06975		-0.8	-2.5	sulfide-dependent adenosine diphosphate thiazole synthase
MMP_RS07700		-0.8	-5.2	DUF1188 domain-containing protein
MMP_RS02245		-0.8	-2.6	hypothetical protein
MMP_RS05060		-0.8	-6.7	AAA family ATPase
MMP_RS03580		-0.8	-3.3	signal recognition particle-docking protein FtsY
MMP_RS08330		-0.8	-5.0	NADH-quinone oxidoreductase subunit H
MMP_RS04615		-0.8	-3.9	PDGLE domain-containing protein
MMP_RS07535		-0.8	-5.1	4Fe-4S binding protein
MMP_RS08725		-0.8	-2.6	Ni/Fe hydrogenase subunit alpha
MMP_RS05545		-0.8	-3.1	pyridoxal phosphate-dependent aminotransferase
MMP_RS04870		-0.8	-3.0	TIGR02253 family HAD-type hydrolase
MMP_RS00620		-0.8	-4.3	4Fe-4S binding protein
MMP_RS05510		-0.8	-3.7	Rrf2 family transcriptional regulator
MMP_RS06200		-0.8	-5.8	M24 family metallopeptidase
MMP_RS06930		-0.8	-5.5	MBL fold metallo-hydrolase
MMP_RS00050		-0.7	-3.9	AarF/UbiB family protein
MMP_RS07380		-0.7	-2.3	transcription elongation factor Spt5
MMP_RS05450		-0.7	-4.0	CoB--CoM heterodisulfide reductase subunit C
MMP_RS01195		-0.7	-1.6	metalloregulator ArsR/SmtB family transcription factor
MMP_RS04850		-0.7	-6.3	UPF0254 family protein
MMP_RS07390		-0.7	-2.5	cell division protein FtsZ
MMP_RS04605		-0.7	-4.8	cobalt ECF transporter T component CbiQ
MMP_RS08445		-0.7	-2.5	DUF2099 family protein
MMP_RS01030		-0.7	-2.1	MTAP family purine nucleoside phosphorylase
MMP_RS00730		-0.7	-4.1	5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB
MMP_RS06370		-0.7	-2.4	biotin synthase BioB
MMP_RS07775		-0.7	-4.5	alanine dehydrogenase
MMP_RS02345		-0.7	-2.1	GTP-dependent dephospho-CoA kinase family protein
MMP_RS03155		-0.7	-4.5	precorrin-6A reductase
MMP_RS04875		-0.7	-2.6	energy-converting hydrogenase B subunit P
MMP_RS00120		-0.7	-2.8	LysR family transcriptional regulator
MMP_RS07630		-0.7	-1.2	ATP-binding cassette domain-containing protein
MMP_RS04620		-0.7	-4.9	cobalt transporter CbiM
MMP_RS07190		-0.7	-4.0	chromosome segregation protein SMC
MMP_RS05850		-0.6	-3.5	Ldh family oxidoreductase
MMP_RS03960		-0.6	-0.8	hypothetical protein
MMP_RS07425		-0.6	-3.2	GTP-binding protein
MMP_RS05440		-0.6	-5.3	winged helix-turn-helix transcriptional regulator
MMP_RS01720		-0.6	-1.5	replication factor C large subunit
MMP_RS07555		-0.6	-0.8	monovalent cation/H+ antiporter subunit E
MMP_RS05100		-0.6	-5.7	CO dehydrogenase/acetyl-CoA synthase complex subunit alpha
MMP_RS02175		-0.6	-0.9	DUF1611 domain-containing protein
MMP_RS03250		-0.6	-3.2	MJ1244 family protein
MMP_RS05425		-0.6	-2.0	monovalent cation/H+ antiporter complex subunit F
MMP_RS07685		-0.6	-3.5	TIGR01212 family radical SAM protein
MMP_RS07200		-0.6	-2.6	[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
MMP_RS07605		-0.6	-1.8	diadenylate cyclase
MMP_RS05065		-0.6	-3.1	CooT family nickel-binding protein
MMP_RS00695		-0.6	-1.0	biotin--[acetyl-CoA-carboxylase] ligase
MMP_RS05345		-0.6	-3.6	hypothetical protein
MMP_RS08165		-0.6	-0.9	phosphoglycerate dehydrogenase
MMP_RS05055		-0.6	-5.1	DUF166 domain-containing protein
MMP_RS08100		-0.6	-3.8	8-amino-7-oxononanoate synthase
MMP_RS02190		-0.6	-2.3	sulfopyruvate decarboxylase subunit alpha
MMP_RS08095		-0.6	-4.0	dethiobiotin synthase
MMP_RS06175		-0.6	-3.7	winged helix-turn-helix transcriptional regulator
MMP_RS04500		-0.6	-4.5	adenosylmethionine--8-amino-7-oxononanoate transaminase
MMP_RS05550		-0.6	-0.7	cation:proton antiporter
MMP_RS06855		-0.6	-3.6	hypothetical protein
MMP_RS03305		-0.6	-3.6	winged helix-turn-helix domain-containing protein
MMP_RS01830		-0.6	-1.5	tRNA-Val
MMP_RS05080		-0.5	-4.3	acetyl-CoA decarbonylase/synthase complex subunit delta
MMP_RS05095		-0.5	-3.3	CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon
MMP_RS00810		-0.5	-2.8	topoisomerase DNA-binding C4 zinc finger domain-containing protein
MMP_RS06940		-0.5	-1.4	polyprenyl diphosphate synthase
MMP_RS00720		-0.5	-3.6	metal-dependent hydrolase
MMP_RS03300		-0.5	-0.9	TOBE domain-containing protein
MMP_RS06215		-0.5	-1.8	30S ribosomal protein S6e

Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments